EKS-OTG-00251

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00251

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	340.0	7.1E-102	27	279	253

Status

Unreviewed

Ensembl Protein

ENSOGAP00000010694

UniProt Accession

H0X5V2;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000011950	ENSOGAP00000010694	ENSOGAT00000011953

Organism

Otolemur garnettii

Functional Description

Protein Length

559

Protein Sequence
(FASTA)

MRRLSSWRKM ATAEKQKHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR 60

QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPSDI FMVMEYVSGG ELFDYICKNG 120

RLDEKESRRL FQQILSGVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF 180

LRTSCGSPNY AAPEVISGRL YAGPEVDIWS SGVILYALLC GTLPFDDDHV PTLFKKICDG 240

IFYTPQYLNP SVISLLKHML QVDPMKRATI KDIREHEWFK QDLPKYLFPE DPSYSSTMID 300

DEALKEVCEK FECSEEEVLS CLYNRNHQDP LAVAYHLIID NRRIMNEAKD FYLATSPPDS 360

FLDDHHLTRP HPERVPFLVA ETPRARHTLD ELNPQKSKHQ GVRKAKWHLG IRSQSRPNDI 420

MAEVCRAIKQ LDYEWKVVNP YYLRVRRKNP VTSTYSKMSL QLYQVDSRTY LLDFRSIDDE 480

ITEAKSGTAT PQRSGSVSNY RSCQRNDSDA EAQGKSSEVS LTSSVTSLDS SPVDLTPRPG 540

SHTIEFFEMC ANLIKILAQ 559

Nucleotide Sequence
(FASTA)

ATGCGCAGAC TCAGTTCCTG GAGAAAGATG GCGACAGCCG AGAAGCAGAA ACACGACGGG 60

CGGGTGAAGA TCGGCCACTA CATCCTGGGA GACACGCTAG GGGTCGGCAC CTTTGGCAAA 120

GTGAAGGTTG GTAAACATGA ATTGACTGGG CATAAAGTTG CTGTGAAGAT TCTCAATCGA 180

CAGAAGATTC GAAGCCTCGA TGTGGTAGGA AAAATCCGCA GAGAAATCCA GAACCTCAAG 240

CTTTTCAGGC ATCCTCATAT AATTAAACTG TACCAGGTCA TCAGTACACC ATCTGATATT 300

TTCATGGTGA TGGAATATGT CTCAGGAGGA GAGCTATTTG ATTATATCTG TAAAAATGGA 360

AGGCTGGATG AAAAAGAAAG TCGACGTCTG TTCCAACAAA TCCTTTCTGG TGTAGATTAT 420

TGTCACAGGC ATATGGTGGT CCATAGAGAT TTGAAACCTG AAAATGTCCT GCTTGATGCA 480

CACATGAATG CAAAGATAGC TGATTTTGGT CTTTCAAACA TGATGTCAGA TGGTGAATTT 540

TTAAGAACAA GTTGTGGCTC ACCCAACTAT GCTGCGCCAG AAGTAATTTC AGGAAGGTTA 600

TATGCAGGCC CAGAGGTGGA TATATGGAGC AGTGGGGTTA TTCTCTATGC TTTATTATGT 660

GGAACGCTTC CATTTGATGA TGATCATGTG CCAACTCTTT TTAAGAAGAT TTGTGATGGA 720

ATCTTTTATA CCCCTCAGTA TTTAAATCCC TCTGTGATTA GCCTCCTGAA ACACATGCTG 780

CAGGTGGATC CCATGAAGAG GGCCACAATC AAAGACATCA GGGAACATGA ATGGTTTAAA 840

CAGGACCTTC CAAAATATCT CTTTCCTGAG GATCCATCAT ATAGTTCAAC CATGATTGAT 900

GATGAAGCCT TAAAAGAAGT ATGTGAAAAA TTTGAATGCT CAGAGGAAGA GGTCCTCAGC 960

TGCCTTTATA ATAGGAATCA CCAGGACCCT TTGGCAGTTG CCTACCATCT CATAATCGAT 1020

AACAGGAGAA TAATGAATGA AGCCAAAGAT TTCTACTTGG CGACGAGCCC ACCTGATTCT 1080

TTTCTCGATG ATCACCATCT GACTCGGCCC CATCCTGAAA GAGTACCATT CTTGGTTGCT 1140

GAAACACCAA GGGCACGCCA TACCCTTGAT GAATTAAATC CACAGAAATC CAAACACCAA 1200

GGCGTACGGA AAGCAAAATG GCATTTAGGA ATTAGAAGTC AAAGTCGACC AAATGATATC 1260

ATGGCAGAAG TATGTAGAGC AATTAAACAG TTGGATTATG AGTGGAAGGT GGTAAACCCA 1320

TATTATTTGC GTGTACGAAG GAAGAATCCT GTGACAAGCA CATACTCCAA AATGAGCCTA 1380

CAGTTATATC AAGTGGATAG CAGAACTTAC TTACTGGATT TCCGTAGTAT TGATGATGAA 1440

ATTACAGAAG CCAAATCAGG GACTGCTACT CCACAGAGAT CGGGATCAGT TAGCAACTAT 1500

CGATCTTGCC AAAGGAATGA TTCAGATGCT GAGGCTCAAG GAAAATCCTC AGAAGTTTCT 1560

CTTACCTCAT CTGTGACCTC ACTTGACTCT TCTCCTGTTG ATTTAACTCC AAGACCAGGA 1620

AGTCACACGA TAGAATTTTT TGAGATGTGT GCAAATCTAA TTAAAATTCT TGCACAGTAA 1680

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ kh++t++kvavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 27    YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  86

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++grl+eke+r+lf+q++s+v+Y+h++ +

Q: 87    IIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMV  146

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 147   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  206

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 207   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMK  266

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 267   RATIKDIREHEWF  279

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGKH ELTGHKVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PSDIFMVMEY VSGGELFDYI CKNGRLDEKE SRRLFQQILS GVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFYTPQ YLNPSVISLL KHMLQVDPMK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013