EKS-OTG-00284

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00284

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	453.1	3.6E-136	181	468	288

Status

Unreviewed

Ensembl Protein

ENSOGAP00000010706

UniProt Accession

H0X5W2;

Protein Name

Protein Synonyms/Alias

Gene Name

ACVR1C

Gene Synonyms/Alias

ACVR1C;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000011965	ENSOGAP00000010706	ENSOGAT00000011968

Organism

Otolemur garnettii

Functional Description

Protein Length

479

Protein Sequence
(FASTA)

ILKLFALLFP GLKCVCLLCD SSNFTCQTEG ACWASVMLTN GKEQVIKSCV SLPELNAQVF 60

CHSSNNVTKT ECCFTDFCNN ITLHLPTASP NAPKLGPMEL AVVITVPVCL VSIAAMLIAW 120

ACQGRWCTYR KKKRSNVEEP LSECNLANAG KTLKDLIYDV TASGSGSGLP LLVQRTIART 180

IVLQEIVGKG RFGEVWHGRW CGEDVAVKIF SSRDERSWFR EAEIYQTVML RHENILGFIA 240

ADNKDNGTWT QLWLVSEYHE QGSLYDYLNR NIVTVAGMIK LALSIASGLA HLHMEIVGTQ 300

GKPAIAHRDI KSKNILVKKC ETCAIADLGL AVKHDSILNT IDIPQNPKVG TKRYMAPEIL 360

DDTMNVNIFD SFKRADIYSV GLVYWEIARR CSVGGIVEEY QLPYYDMVPS DPSIEEMRKV 420

VCDQKLRPSI PNQWQSCEAL RVMGRIMREC WYANGAARLT ALRIKKTISQ LCVKEDCKA 479

Nucleotide Sequence
(FASTA)

ATTTTAAAGC TTTTTGCCTT ACTCTTTCCA GGACTGAAAT GTGTATGTCT TTTGTGTGAT 60

TCTTCAAACT TTACCTGCCA AACAGAAGGA GCTTGTTGGG CATCAGTTAT GCTAACTAAT 120

GGAAAAGAAC AGGTGATCAA ATCCTGTGTC TCCCTCCCAG AATTAAATGC TCAAGTCTTC 180

TGTCATAGTT CCAATAATGT TACCAAAACC GAGTGCTGCT TCACAGATTT TTGCAACAAC 240

ATAACACTGC ACCTTCCAAC AGCCTCACCA AATGCTCCAA AACTTGGACC CATGGAACTG 300

GCTGTTGTCA TTACTGTGCC TGTGTGCCTC GTGTCCATAG CTGCCATGCT GATAGCATGG 360

GCCTGCCAAG GGCGGTGGTG CACCTATAGG AAGAAAAAGA GATCCAATGT GGAGGAACCG 420

CTCTCTGAGT GCAACCTCGC AAATGCTGGA AAGACCCTTA AAGACCTGAT CTATGATGTG 480

ACTGCCTCCG GTTCTGGCTC TGGTCTACCT CTGTTGGTTC AAAGAACAAT TGCAAGAACG 540

ATTGTACTTC AGGAAATAGT AGGAAAAGGT AGATTTGGTG AGGTGTGGCA TGGACGATGG 600

TGTGGGGAAG ATGTGGCTGT GAAAATATTC TCCTCCAGAG ACGAACGATC ATGGTTTCGA 660

GAGGCAGAAA TTTATCAGAC GGTCATGCTG CGACACGAGA ACATCCTGGG TTTCATTGCC 720

GCTGATAACA AAGATAATGG AACTTGGACT CAGCTTTGGC TTGTATCTGA ATATCATGAA 780

CAGGGTTCCT TATATGACTA TCTGAATAGA AATATAGTGA CAGTGGCTGG AATGATCAAA 840

CTGGCACTTT CAATAGCTAG TGGTCTAGCT CACCTTCATA TGGAGATCGT TGGCACACAA 900

GGGAAACCTG CTATTGCTCA TCGAGATATA AAATCAAAGA ATATTTTAGT GAAAAAATGT 960

GAAACTTGTG CCATAGCAGA TTTGGGGTTG GCTGTGAAGC ACGATTCAAT ACTGAACACT 1020

ATTGACATAC CTCAGAATCC TAAAGTGGGG ACCAAGAGGT ATATGGCTCC TGAAATACTT 1080

GATGACACAA TGAATGTGAA TATCTTTGAC TCTTTTAAAC GAGCAGACAT CTACTCTGTT 1140

GGTCTGGTTT ACTGGGAAAT AGCCCGCAGG TGTTCAGTGG GAGGAATTGT TGAGGAGTAC 1200

CAGTTGCCTT ATTACGACAT GGTGCCTTCA GATCCCTCGA TAGAGGAAAT GAGGAAGGTT 1260

GTGTGTGACC AGAAACTCCG ACCGAGTATC CCAAACCAGT GGCAAAGCTG TGAAGCACTC 1320

CGAGTCATGG GAAGAATAAT GCGTGAGTGT TGGTATGCCA ACGGGGCAGC CCGCCTAACT 1380

GCCCTTCGTA TTAAGAAGAC TATTTCTCAA CTTTGTGTCA AAGAAGACTG CAAAGCCTGA 1440

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         + l+e++gkGr+geVw++++ ge+vAvKifs++de+sw+rE+eiyqtv+lrhenil+fia

Q: 181   IVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIA  240

         5789********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k+++++t+l+lv+eyhe+gsL+dyL+r++++v  +++lals+asGlahLH+eivgt+

Q: 241   ADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQ  300

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRD+kskNilvkk +tc+iaDlGLa+k+++  +++d+ +n +vGtkRYmaPE

Q: 301   G--KPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPE  358

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         +l++++n++ f++fkraD+Ys+gLv+WE+a+Rc+  +++veey+lp++++v+sdPs+eem

Q: 359   ILDDTMNVNIFDSFKRADIYSVGLVYWEIARRCSV-GGIVEEYQLPYYDMVPSDPSIEEM  417

         **********************************9.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         ++vv+++klrP+ip++w+++eal+++ ++++ecW+a+++aRltalr+kk++

Q: 418   RKVVCDQKLRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTI  468

         ************************************************986

Domain Sequence
(FASTA)

IVLQEIVGKG RFGEVWHGRW CGEDVAVKIF SSRDERSWFR EAEIYQTVML RHENILGFIA 60

ADNKDNGTWT QLWLVSEYHE QGSLYDYLNR NIVTVAGMIK LALSIASGLA HLHMEIVGTQ 120

GKPAIAHRDI KSKNILVKKC ETCAIADLGL AVKHDSILNT IDIPQNPKVG TKRYMAPEIL 180

DDTMNVNIFD SFKRADIYSV GLVYWEIARR CSVGGIVEEY QLPYYDMVPS DPSIEEMRKV 240

VCDQKLRPSI PNQWQSCEAL RVMGRIMREC WYANGAARLT ALRIKKTI 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013