EKS-OTG-00428

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00428

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	441.3	1.3E-132	163	422	260

Status

Unreviewed

Ensembl Protein

ENSOGAP00000011066

UniProt Accession

H0X6R0;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000012362	ENSOGAP00000011066	ENSOGAT00000012368

Organism

Otolemur garnettii

Functional Description

Protein Length

499

Protein Sequence
(FASTA)

IQRDYTMDYK ESCPSVSIPS SDEHREKKKR FTVYKVLVSV GRSEWFVFRR YAEFDKLYNT 60

LKKQFPAMAL KIPAKRIFGD NFDPDFIKQR RAGLNEFIQN LVRHPELYNH PDVRAFLQMD 120

SPKHQSDPSE DEDERSIQKV LHSTSQNINL GPSGNPHAKP TDFDFLKVIG KGSFGKVLLA 180

KRKLDGKFYA VKVLQKKIVL NRKEQKHIMA ERNVLLKNVK HPFLVGLHYS FQTTEKLYFV 240

LDFVNGGELF VGKVHKRKAP WHEATDRLHG HTCHQAIEHE HNLDLLFRFL RFEIILSASV 300

GHVVLTDFGL CKEGIAISDT TTTFCGTPEY LAPEVIRKQP YDNTVDWWCL GAVLYEMLYG 360

LPPFYCRDVA EMYDNILHKP LNLRPGVSLT AWSILEELLE KDRQNRLGAK EDFLEIQNHP 420

FFESLSWTDL VQKKIPPPFN PNVAGPDDIR NFDTAFTEET VPYSVCVSSD YSVVNASVLE 480

ADDAFLGFSY APPSEDLFL 499

Nucleotide Sequence
(FASTA)

ATTCAAAGAG ATTATACCAT GGACTACAAG GAAAGCTGCC CAAGTGTAAG CATTCCCAGC 60

TCTGATGAAC ACAGAGAGAA AAAGAAGAGG TTCACTGTTT ATAAAGTTCT GGTCTCAGTG 120

GGCAGGAGTG AATGGTTTGT CTTCAGGAGA TATGCAGAGT TTGATAAACT TTATAATACT 180

TTAAAGAAGC AGTTTCCTGC TATGGCCTTG AAGATTCCTG CCAAGAGAAT ATTTGGTGAT 240

AATTTTGATC CAGATTTTAT TAAACAAAGA AGAGCAGGAC TGAATGAATT TATTCAGAAC 300

CTAGTTAGAC ATCCAGAGCT CTATAACCAT CCAGATGTCA GAGCATTCCT TCAAATGGAC 360

AGTCCAAAAC ATCAGTCAGA TCCATCTGAA GATGAGGATG AAAGAAGTAT TCAGAAGGTA 420

CTACACTCTA CCTCACAGAA CATCAACCTG GGACCATCTG GAAATCCTCA TGCTAAACCA 480

ACTGACTTTG ATTTCTTAAA AGTTATTGGA AAAGGCAGCT TTGGCAAGGT TCTTCTTGCA 540

AAACGGAAAC TGGATGGAAA ATTTTATGCT GTCAAAGTGT TACAGAAAAA AATAGTTCTC 600

AACAGAAAAG AGCAAAAACA TATTATGGCT GAACGTAATG TGCTTTTGAA AAATGTGAAA 660

CATCCATTTT TGGTTGGATT ACATTATTCT TTCCAAACAA CTGAAAAGCT TTATTTTGTT 720

CTGGATTTTG TTAATGGAGG GGAGCTATTT GTTGGGAAGG TTCATAAAAG AAAAGCACCT 780

TGGCACGAAG CAACAGACAG ACTTCATGGA CATACTTGTC ACCAAGCTAT AGAGCATGAG 840

CACAACCTTG ATCTTCTTTT TAGATTTTTA AGATTTGAAA TTATTCTGTC AGCATCTGTG 900

GGACATGTTG TCTTAACAGA TTTTGGGCTT TGTAAAGAAG GAATTGCTAT TTCTGATACT 960

ACAACAACAT TTTGTGGGAC ACCAGAGTAC CTTGCACCTG AAGTAATCAG AAAACAGCCT 1020

TATGATAATA CTGTAGATTG GTGGTGTCTT GGTGCTGTTC TGTATGAAAT GCTGTATGGA 1080

TTGCCTCCTT TTTATTGCCG AGATGTTGCT GAAATGTATG ACAATATCCT TCACAAACCC 1140

CTAAATTTGA GGCCAGGAGT GAGCCTCACA GCCTGGTCCA TTCTGGAGGA ACTTCTAGAA 1200

AAAGACAGGC AAAATCGACT CGGTGCCAAA GAAGACTTTC TTGAAATTCA GAATCATCCT 1260

TTTTTTGAAT CACTCAGCTG GACTGACCTT GTACAAAAGA AGATTCCACC ACCATTTAAT 1320

CCTAATGTGG CTGGACCAGA TGATATCAGG AACTTTGACA CAGCATTCAC AGAAGAAACA 1380

GTTCCGTATT CTGTGTGCGT GTCGTCTGAC TATTCGGTAG TGAATGCCAG TGTTTTGGAG 1440

GCTGATGACG CATTCCTTGG TTTCTCTTAC GCACCTCCTT CAGAAGACTT ATTTTTGTGA 1500

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++l++ke+khimaernvllknvkhp

Q: 163   FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP  222

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhl..qrersfleprarfyaaeiasalgylhs  118

         flvglhysfqt+eklyfvld+vnggelf+    +r+  + e+  r++      a+ + h+

Q: 223   FLVGLHYSFQTTEKLYFVLDFVNGGELFVGKvhKRKAPWHEATDRLHGHTCHQAIEHEHN  282

         ****************************865115666789999*****************

S: 119   lnivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpyd  178

         l++++r l+ e il  s ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd

Q: 283   LDLLFRFLRFEIILSASVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYD  342

         ************************************************************

S: 179   rtvdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekd  238

         +tvdwwclgavlyemlyglppfy+rdvaemydnil+kpl+l+pg+s++a+++leellekd

Q: 343   NTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKD  402

         ************************************************************

S: 239   rkkrlgakedfleiknhvff  258

         r++rlgakedflei+nh+ff

Q: 403   RQNRLGAKEDFLEIQNHPFF  422

         *******************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFVG KVHKRKAPWH EATDRLHGHT CHQAIEHEHN 120

LDLLFRFLRF EIILSASVGH VVLTDFGLCK EGIAISDTTT TFCGTPEYLA PEVIRKQPYD 180

NTVDWWCLGA VLYEMLYGLP PFYCRDVAEM YDNILHKPLN LRPGVSLTAW SILEELLEKD 240

RQNRLGAKED FLEIQNHPFF 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013