EPS-OTG-00055

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00055

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	284.7	3.6E-85	130	300	171

Status

Unreviewed

Ensembl Protein

ENSOGAP00000011173

UniProt Accession

H0X707;

Protein Name

Protein Synonyms/Alias

Gene Name

TENC1

Gene Synonyms/Alias

TENC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000012472	ENSOGAP00000011173	ENSOGAT00000012483

Organism

Otolemur garnettii

Functional Description

Protein Length

1416

Protein Sequence
(FASTA)

EGGGVCVRRG PPVQSSALGT LLRKESRTRR MKPRKAEPHS FREKVFRKKP PVCAVCKVTI 60

DGTGVSCRVC KMATHRKCEA KVTSSCQALP PVELRRNTAP VRRIEHLGST KSLNYSKQRS 120

TLPRSFSLDP LMERRWDLDL TYVTERILAA AFPSRPDEQQ HRGHLRELAH VLQSKHRDKY 180

LLFNLSEKRH DLTRLNPKVQ DFGWPELHAP PLDKLCSICK AMETWLSADP QHVVVLYCKG 240

SKGKLGVIVS AYMHYSKISA GADQALATLT MRKFCEDKVA TELQPSQRRY IGYFSGLLSG 300

SIRMNSSPLF LHYVLVPMLP AFEPSTGFQP FLKIYQSMQL VYTSGVYHIA GPGPQQLCIG 360

LEPALLLKGD VMVTCYHKGG HGTDRTLVFR VQFHTCTIHG PRLAFPKDQL DEAWTDERFP 420

FQASVEFVFS SSPEKIKGNT PRNDPSVSVD YNTTEPAVRW DSYENFNRHH EDSVDGSLTH 480

TRGPLDGSPY AQVQRAPRQT PPAPSPEPPP PPMLSVSSDS GHSSTLTTEP AAESPGRPPP 540

TAAERQELDR LLGGCGVASG GRGAGRETAI LDDEEQPPVG GGPHLGVYSS HRLALSRHCS 600

CRQGYREACG VPSGGYYRPE GTLERRRLPY GGFEGPPQGY AEASMEKRRL CRSLSEGPYP 660

YPPELGKPPN GDFGYRSPAY REVVILEDPA LPALCSCPAC DEKLALPTAA LYGLRLEREA 720

GEGWASEAAK PLLHPVRPGP PLPLLVPTCG HHHAPVPEYS CLKPPRAGEE GHEGCSYTMC 780

PEGRYGHPGC PALVTYSCGG AVPTYCPAYG RVPHSCGSPG EGRGYPSPGT HSPRAGSISP 840

GSPPYPQSRK LSYEIPAEEG GSRYPLPGHL ASAGPLASAE SPEPVSWREG PSGHSTLPRS 900

PQDPQGSASS ELSGPSIPLH TSSPVQGKES TRRQDTRSPT LAPMQRLSPG EGLPSVPQGG 960

AGKAPELPAR NGPEPAASGL CSPTSTPSSP ADWPQERSPG GHSDTASPQG PVPTTLPGLR 1020

HTPWQSPRGP PDSPDGSPLT PVPTQMPWLV TSPEPPQSSP TPAFPLAAAY DTNGPTQPPL 1080

PEKRHLLGPG QQTGPWGPEQ ASPPARGTNH HVTFAPLLPD SAPQAPEPPM QESQSNVKFV 1140

QDTSKFWYKP HLSRDQAIAL LKDKDPGAFL IRDSHSFQGA YGLALKVATP PPSAQPWKGD 1200

PLEQLVRHFL IETGPKGVKI KGCPSEPYFG SLSALVSQHS ISPISLPCCL RIPSKDPLEE 1260

TPEAPVPSNM STAADLLRQG AACSVLYLTS VETESLTGPQ AVARASSAAL SCTPRPTPAV 1320

VHFKVSAQGI TLTDNQRKLF FRRHYPVNSI TFSSTDPQDR RWTNPDGTTS KIFGFVAKKP 1380

GSPWENVCHL FAELDPDQPA GAIVTFITKV LLGQRK 1416

Nucleotide Sequence
(FASTA)

GAAGGGGGTG GAGTATGTGT TAGGAGGGGT CCTCCTGTCC AGTCCTCGGC CCTGGGAACG 60

CTGCTGAGGA AAGAGAGCAG AACTAGGAGA ATGAAGCCTA GGAAAGCTGA GCCACACAGC 120

TTCCGGGAGA AGGTTTTCCG GAAGAAACCT CCAGTCTGTG CAGTGTGTAA GGTGACCATC 180

GACGGGACAG GCGTCTCATG CAGAGTCTGC AAGATGGCAA CACACAGAAA ATGTGAAGCA 240

AAGGTGACTT CTTCCTGTCA GGCCTTGCCT CCTGTGGAGC TGCGACGAAA CACAGCCCCA 300

GTCAGGCGCA TAGAGCATCT GGGATCCACC AAATCTCTAA ACTATTCAAA GCAGCGGAGC 360

ACTCTGCCTA GGAGCTTCAG CCTGGACCCG CTCATGGAGA GGCGCTGGGA CCTGGACCTC 420

ACCTACGTGA CGGAACGCAT CCTGGCCGCC GCCTTCCCCT CGCGGCCCGA TGAACAGCAA 480

CACCGGGGCC ACCTGCGAGA GTTGGCCCAC GTGCTGCAAT CCAAACACCG CGACAAGTAC 540

CTGCTCTTCA ACCTTTCAGA GAAAAGGCAT GACCTGACCC GCCTAAACCC CAAGGTCCAG 600

GATTTTGGCT GGCCTGAGCT GCATGCCCCA CCCCTGGACA AGTTGTGCTC CATCTGCAAA 660

GCCATGGAGA CGTGGCTCAG TGCTGACCCA CAGCACGTTG TGGTACTGTA TTGCAAGGGA 720

AGCAAAGGCA AGCTCGGGGT CATTGTTTCT GCCTACATGC ACTACAGCAA GATCTCTGCA 780

GGGGCAGACC AAGCACTGGC TACTCTTACC ATGCGGAAAT TCTGTGAGGA CAAGGTGGCC 840

ACAGAACTTC AGCCCTCCCA GCGCCGATAC ATTGGCTATT TCAGTGGGCT GCTATCTGGC 900

TCCATCAGGA TGAACAGCAG TCCTCTCTTC CTGCACTATG TGCTCGTGCC CATGCTTCCA 960

GCCTTCGAAC CCAGCACAGG CTTCCAGCCC TTCCTGAAAA TCTATCAGTC CATGCAGCTC 1020

GTCTACACAT CCGGAGTCTA CCACATCGCA GGCCCTGGTC CCCAGCAGCT CTGCATTGGC 1080

CTGGAGCCAG CACTCCTCCT CAAAGGCGAT GTCATGGTCA CATGCTATCA CAAGGGTGGC 1140

CATGGCACAG ACCGGACTCT TGTGTTCCGA GTCCAGTTCC ACACATGCAC CATCCATGGA 1200

CCACGGCTCG CCTTCCCCAA GGACCAGCTG GACGAGGCCT GGACTGATGA GAGGTTCCCC 1260

TTCCAAGCCT CAGTGGAGTT TGTGTTTTCC TCTAGCCCTG AGAAGATCAA AGGTAACACT 1320

CCACGGAATG ATCCCTCTGT CTCTGTTGAC TACAATACCA CAGAGCCTGC CGTGCGATGG 1380

GACTCCTACG AGAACTTCAA CCGGCACCAT GAAGACAGTG TGGATGGCTC CCTGACCCAT 1440

ACCCGTGGTC CCTTGGACGG CAGTCCCTAT GCCCAGGTGC AGCGGGCACC CCGCCAGACC 1500

CCACCAGCAC CTTCTCCAGA GCCACCCCCA CCCCCCATGC TCTCTGTCAG CAGTGACTCC 1560

GGCCACTCAT CCACACTCAC CACAGAGCCA GCTGCTGAGT CCCCTGGCCG GCCGCCTCCT 1620

ACAGCTGCTG AGCGGCAGGA GCTAGATCGC CTCCTGGGAG GCTGTGGAGT GGCCAGTGGG 1680

GGCCGAGGGG CTGGGCGTGA GACGGCCATC TTAGATGACG AAGAGCAGCC CCCTGTGGGT 1740

GGAGGCCCCC ACCTTGGAGT GTACTCCAGT CATAGGCTTG CCCTCAGCCG CCACTGCTCC 1800

TGCCGCCAGG GCTACCGGGA GGCCTGTGGA GTCCCCAGTG GGGGGTACTA CCGGCCAGAA 1860

GGAACCCTGG AAAGGCGACG ACTGCCCTAT GGGGGCTTTG AGGGCCCCCC GCAGGGCTAT 1920

GCTGAGGCCT CCATGGAAAA GAGGCGCCTC TGCCGCTCAC TATCTGAGGG GCCCTACCCC 1980

TACCCACCTG AGCTGGGAAA ACCACCCAAT GGGGACTTTG GCTACCGCTC CCCGGCCTAC 2040

CGAGAGGTGG TCATCCTGGA GGACCCTGCA CTGCCTGCCT TATGTTCATG CCCGGCCTGT 2100

GATGAGAAGC TGGCACTACC CACAGCAGCC CTGTATGGAC TGCGGCTGGA GAGAGAGGCT 2160

GGTGAAGGGT GGGCAAGTGA GGCAGCCAAG CCTCTCCTGC ACCCAGTACG GCCTGGGCCC 2220

CCGTTGCCTC TGCTAGTGCC CACCTGTGGG CATCACCATG CCCCAGTGCC TGAGTACAGC 2280

TGCCTGAAGC CACCCAGGGC AGGTGAGGAA GGGCACGAGG GCTGTTCCTA CACCATGTGC 2340

CCTGAGGGCA GGTATGGGCA TCCAGGGTGC CCTGCCCTGG TGACGTACAG CTGTGGAGGA 2400

GCAGTTCCCA CTTACTGCCC AGCATATGGT CGGGTGCCTC ACAGCTGTGG ATCTCCAGGC 2460

GAGGGCAGAG GGTATCCCAG CCCTGGTACC CACTCCCCAC GGGCTGGCTC CATCTCCCCG 2520

GGCAGCCCGC CCTACCCACA ATCCAGGAAG CTGAGCTACG AGATCCCTGC GGAGGAAGGA 2580

GGGAGCAGGT ACCCACTGCC TGGGCACCTC GCCTCAGCAG GACCCTTGGC CTCTGCAGAG 2640

TCACCAGAGC CAGTGTCCTG GAGGGAGGGC CCCAGTGGGC ATAGCACGCT GCCTCGGTCT 2700

CCCCAAGATC CCCAGGGCAG TGCCTCTTCA GAGTTGTCTG GTCCCTCCAT ACCCCTGCAC 2760

ACCAGCAGCC CAGTCCAGGG CAAGGAAAGC ACCCGACGAC AAGACACCAG GTCCCCCACC 2820

TTGGCGCCCA TGCAGAGACT GAGTCCTGGC GAGGGCTTGC CCTCTGTTCC CCAAGGAGGT 2880

GCTGGAAAGG CTCCTGAGCT GCCAGCAAGA AATGGGCCTG AGCCTGCAGC CTCTGGCCTC 2940

TGCTCCCCAA CCTCCACTCC CAGCTCACCT GCTGATTGGC CTCAGGAAAG GAGCCCAGGG 3000

GGCCACTCAG ACACTGCCAG TCCCCAGGGA CCCGTGCCTA CCACACTGCC TGGCCTCCGC 3060

CACACCCCCT GGCAGAGCCC TCGAGGCCCC CCAGACAGCC CAGATGGGTC CCCCCTCACT 3120

CCTGTGCCTA CCCAGATGCC CTGGCTTGTG ACCAGCCCAG AGCCCCCTCA GAGCTCACCC 3180

ACACCTGCCT TCCCCCTGGC TGCCGCTTAT GATACCAATG GCCCTACTCA GCCCCCACTT 3240

CCTGAGAAAC GCCACCTGCT GGGGCCTGGG CAACAGACAG GACCCTGGGG CCCAGAGCAG 3300

GCTTCACCAC CAGCCAGAGG CACCAATCAC CATGTTACCT TCGCACCTCT GCTTCCAGAT 3360

AGTGCCCCTC AAGCCCCAGA GCCCCCCATG CAAGAGAGCC AAAGCAATGT AAAGTTTGTC 3420

CAAGATACAT CTAAGTTCTG GTACAAGCCA CACCTGTCCC GTGACCAAGC CATTGCCTTG 3480

CTGAAAGACA AGGACCCTGG GGCCTTCTTG ATCAGGGACA GTCATTCATT CCAAGGAGCT 3540

TATGGGCTAG CCCTCAAAGT GGCCACACCT CCACCCAGTG CTCAGCCCTG GAAAGGGGAC 3600

CCCTTGGAAC AGCTGGTCCG CCATTTCCTC ATTGAGACTG GGCCCAAAGG GGTGAAGATC 3660

AAGGGCTGTC CTAGTGAGCC CTACTTTGGC AGCCTGTCCG CCCTGGTCTC CCAGCACTCC 3720

ATCTCCCCCA TCTCTCTGCC CTGCTGCCTA CGCATTCCCA GTAAAGATCC TCTGGAAGAG 3780

ACCCCAGAGG CTCCAGTGCC TTCCAACATG AGCACAGCGG CGGACCTCCT ACGTCAGGGT 3840

GCTGCCTGCA GCGTACTCTA CCTGACCTCA GTGGAGACAG AATCACTTAC AGGCCCCCAA 3900

GCTGTGGCCC GGGCCAGTTC TGCAGCTCTG AGCTGCACCC CCCGCCCAAC ACCAGCCGTT 3960

GTCCACTTCA AGGTCTCAGC CCAGGGCATT ACACTGACTG ACAACCAAAG GAAGCTATTC 4020

TTTCGCCGCC ATTATCCAGT GAACAGCATC ACCTTCTCCA GCACAGACCC TCAGGACCGG 4080

AGATGGACCA ACCCAGACGG GACCACCTCC AAGATCTTTG GTTTCGTGGC CAAGAAGCCG 4140

GGAAGCCCCT GGGAGAATGT GTGTCACCTC TTTGCAGAGC TTGACCCAGA TCAGCCTGCA 4200

GGCGCCATTG TCACCTTCAT CACCAAAGTT CTTCTGGGCC AGAGAAAATG A 4251

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         +l+e+++dldltyvteri+a++fP++++e+++r++lre++++l+skhr+ky+l+nl se+

Q: 130   PLMERRWDLDLTYVTERILAAAFPSRPDEQQHRGHLRELAHVLQSKHRDKYLLFNL-SEK  188

         79******************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         r+dlt+ln+kv++fg+++l+aP+l+kl+sick++++Wls+d+++vvvl+ckg+kg+lGvi

Q: 189   RHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVI  248

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         v+ay+++s+isa+ad+al+t+++r+++edkva++ qPsqrry+ yfs+ll+g

Q: 249   VSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYIGYFSGLLSG  300

         *************************************************997

Domain Sequence
(FASTA)

PLMERRWDLD LTYVTERILA AAFPSRPDEQ QHRGHLRELA HVLQSKHRDK YLLFNLSEKR 60

HDLTRLNPKV QDFGWPELHA PPLDKLCSIC KAMETWLSAD PQHVVVLYCK GSKGKLGVIV 120

SAYMHYSKIS AGADQALATL TMRKFCEDKV ATELQPSQRR YIGYFSGLLS G 171

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0046872	; F:metal ion binding
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00130	; C1_1; 1.
PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00109	; C1; 1.
SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

Created Date

20-Feb-2013