EKS-OTG-00221

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00221

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	596.8	1.2E-179	156	512	357

Status

Unreviewed

Ensembl Protein

ENSOGAP00000011763

UniProt Accession

H0X8F0;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000013125	ENSOGAP00000011763	ENSOGAT00000013135

Organism

Otolemur garnettii

Functional Description

Protein Length

581

Protein Sequence
(FASTA)

MAVRQALGRG LQLGRALLLR LTAKPGPVYG WGRPGPAAGW GRGERPGWAV GPGAEPRRVG 60

LGLPDRYRFF RQSVAGLAAR LQRQFVMRAR GGAGPCGRAV FLAFGLGLGL IEEKQAEGRR 120

AASACQEIQE IFTQKNKLVP NPLDTRRWQG FQLEEYLIGQ SIGKGCSAAV YEATMPALPQ 180

NQEMAKTLEL LPGKEPGIIP QGRKETQAAG APAFPLAIKM MWNISAGSSS EAIFSTMSQE 240

LVPASRVALA GEYGAVTDRK PKGGPKQLAP HPNIIRVLRA FTSSVPLLPG ALVDYPDVLP 300

PRLHPEGLGH GRTLFLVMKN YPCTLRQYLR ENTPSPHLAT LMTLQLLEGV DHLVQQGIAH 360

RDLKSDNILV ELDADGCPWL VITDFGCCLA DESIGLQLPF TSWYVDRGGN GCLMAPEVST 420

AHPGPRAVID YSKADAWAVG AIAYEIFGLA NPFYGQGKAH LESRSYQEAQ LPALPESVPR 480

DMRQLVKSLL QREPSKRPSA RVAANVLHLS LWGEQILALK NLKLDRMIGW LLQQSAVTLL 540

ADRLTEKSCV ETKMKMLFLA NLEWEALCQA ALLLCSWRAA P 581

Nucleotide Sequence
(FASTA)

ATGGCGGTGC GGCAGGCGCT GGGCCGGGGC CTGCAGCTGG GTCGGGCGCT GCTGCTGCGC 60

CTCACGGCCA AGCCTGGCCC GGTCTACGGC TGGGGGCGGC CTGGCCCAGC GGCGGGCTGG 120

GGCCGCGGAG AGCGCCCGGG CTGGGCCGTA GGTCCCGGCG CGGAGCCGCG CAGAGTCGGG 180

CTCGGGCTCC CCGACCGCTA CCGCTTCTTT CGCCAGTCGG TGGCAGGACT GGCGGCACGG 240

CTGCAGCGGC AGTTCGTGAT GCGGGCCCGG GGCGGCGCGG GCCCGTGCGG CCGGGCCGTC 300

TTTCTGGCCT TTGGGCTGGG GCTGGGCCTC ATCGAGGAGA AGCAAGCGGA GGGCCGGCGG 360

GCGGCCTCGG CCTGTCAGGA GATCCAGGAG ATTTTTACCC AGAAAAACAA GCTGGTGCCT 420

AACCCATTGG ATACTAGACG CTGGCAGGGC TTCCAGCTGG AGGAGTATCT TATAGGGCAA 480

TCCATTGGCA AGGGCTGCAG TGCTGCTGTG TATGAAGCCA CCATGCCTGC ATTGCCCCAG 540

AACCAGGAGA TGGCAAAGAC CTTGGAGCTT CTTCCAGGGA AAGAACCAGG TATCATCCCA 600

CAAGGAAGAA AGGAGACTCA AGCTGCAGGG GCCCCTGCCT TCCCCTTAGC CATCAAGATG 660

ATGTGGAACA TCTCGGCGGG CTCTTCTAGC GAAGCCATCT TCAGCACAAT GAGCCAGGAG 720

CTAGTCCCAG CTAGCCGAGT GGCCTTGGCC GGGGAGTATG GCGCAGTTAC GGATAGAAAA 780

CCCAAGGGAG GTCCCAAGCA GTTGGCCCCT CACCCCAACA TCATCCGGGT TCTCCGCGCC 840

TTCACCTCAT CTGTGCCGCT GCTGCCAGGG GCCCTGGTCG ACTACCCTGA TGTGCTGCCT 900

CCACGTCTCC ACCCAGAAGG TCTGGGCCAT GGCCGGACAC TGTTCCTCGT CATGAAGAAC 960

TATCCCTGTA CCCTGCGCCA GTACCTTCGT GAGAACACCC CCAGCCCACA CCTGGCCACC 1020

TTGATGACCC TACAGTTACT GGAAGGAGTG GATCATCTGG TCCAACAGGG CATTGCACAC 1080

AGAGACTTAA AATCTGACAA CATTCTCGTG GAGCTGGACG CAGATGGCTG CCCCTGGCTG 1140

GTGATCACAG ATTTTGGCTG CTGCCTGGCT GACGAGAGCA TCGGCCTGCA GTTGCCCTTC 1200

ACCAGCTGGT ATGTGGATCG GGGTGGAAAC GGCTGCCTGA TGGCTCCTGA GGTGTCCACG 1260

GCCCATCCTG GCCCCAGGGC AGTGATTGAC TACAGCAAGG CTGACGCCTG GGCAGTTGGA 1320

GCCATCGCCT ACGAAATCTT TGGGCTTGCC AATCCCTTTT ATGGCCAAGG CAAGGCCCAC 1380

CTTGAAAGCC GCAGTTACCA AGAGGCTCAA CTTCCTGCAC TGCCTGAGTC GGTTCCTCGA 1440

GACATGAGAC AGCTGGTGAA GTCACTGCTC CAGCGAGAGC CCAGCAAGAG ACCTTCTGCC 1500

CGAGTAGCTG CAAATGTGCT TCATCTCAGC CTCTGGGGTG AACAGATTCT AGCCCTGAAG 1560

AATCTGAAGT TAGACAGGAT GATTGGCTGG CTCCTGCAAC AATCAGCTGT TACTTTGTTG 1620

GCCGACAGGC TCACAGAGAA GAGTTGTGTG GAAACAAAAA TGAAGATGCT CTTTCTAGCC 1680

AACCTAGAGT GGGAAGCGCT CTGCCAGGCA GCCCTCCTCC TCTGCTCATG GAGGGCAGCC 1740

CCTTGA 1746

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeidqesavaakkfp  59

         ylig+++gkgc+aavyeat+++l+q+ e ak l ll gke++ + ++ ++ +a++a++fp

Q: 156   YLIGQSIGKGCSAAVYEATMPALPQNQEMAKTLELLpGKEPGIIPQGRKETQAAGAPAFP  215

         99********************************999***********************

S: 60    laiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPniv  111

         laik+m+ni+a+sssea++++msqelvpasrval+geygav        pk+la+hPni+

Q: 216   LAIKMMWNISAGSSSEAIFSTMSQELVPASRVALAGEYGAVtdrkpkggPKQLAPHPNII  275

         ************************************************************

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rvlraf++sv+llP+al+dyPd+lp+rl+peglg+g+tl+lvmk+y++tlr+yl ++++s

Q: 276   RVLRAFTSSVPLLPGALVDYPDVLPPRLHPEGLGHGRTLFLVMKNYPCTLRQYLRENTPS  335

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         ++la+l+++qlle+vdhlv++g+ahrdlksdnilveld d++P+lvi+dfGCclad+++g

Q: 336   PHLATLMTLQLLEGVDHLVQQGIAHRDLKSDNILVELDADGCPWLVITDFGCCLADESIG  395

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp++s++vd+GGn++lmaPe+sta+pGp+avi+y+kad+WavGa+ayeifgl+nPfyg

Q: 396   LQLPFTSWYVDRGGNGCLMAPEVSTAHPGPRAVIDYSKADAWAVGAIAYEIFGLANPFYG  455

         ************************************************************

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

         +gka+les+syqeaqlPalpesvp ++rqlv +ll+re+skr+sa++aanvl+lsl+

Q: 456   QGKAHLESRSYQEAQLPALPESVPRDMRQLVKSLLQREPSKRPSARVAANVLHLSLW  512

         ********************************************************9

Domain Sequence
(FASTA)

YLIGQSIGKG CSAAVYEATM PALPQNQEMA KTLELLPGKE PGIIPQGRKE TQAAGAPAFP 60

LAIKMMWNIS AGSSSEAIFS TMSQELVPAS RVALAGEYGA VTDRKPKGGP KQLAPHPNII 120

RVLRAFTSSV PLLPGALVDY PDVLPPRLHP EGLGHGRTLF LVMKNYPCTL RQYLRENTPS 180

PHLATLMTLQ LLEGVDHLVQ QGIAHRDLKS DNILVELDAD GCPWLVITDF GCCLADESIG 240

LQLPFTSWYV DRGGNGCLMA PEVSTAHPGP RAVIDYSKAD AWAVGAIAYE IFGLANPFYG 300

QGKAHLESRS YQEAQLPALP ESVPRDMRQL VKSLLQREPS KRPSARVAAN VLHLSLW 357

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>