EKS-OTG-00301

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00301

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IKK	432.7	5.6E-130	15	288	274

Status

Unreviewed

Ensembl Protein

ENSOGAP00000012026

UniProt Accession

H0XN60;

Protein Name

Protein Synonyms/Alias

Gene Name

CHUK

Gene Synonyms/Alias

CHUK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000013415	ENSOGAP00000017551	ENSOGAT00000032293
ENSOGAG00000013415	ENSOGAP00000012026	ENSOGAT00000013425

Organism

Otolemur garnettii

Functional Description

Protein Length

745

Protein Sequence
(FASTA)

MERPPGLRPG AGGPWEMRER LGTGGFGNVC LYQHRELDLK VAIKSCRLEL STKNRERWCH 60

EIQIMKKLNH TNVVKACDVP EELNILINDV PLLAMEYCSG GDLRKLLNKP ENCCGLKESQ 120

ILSLLSDIGS GIRYLHENKI IHRDLKPENI VLQDVGGKVT HKIIDLGYAK DVDQGSLCTS 180

FVGTLQYLAP ELFENKPYTA TVDYWSFGTM VFECIAGYRP FLHHLQPFTW HEKIKKKDPK 240

CIFACEEMTG EVRFSSHLPQ PNSLCSLIVE PMENWLQLML NWDPQQRGGP IDHTLKQPRC 300

FLLMDHILNL KIVHILNMTS AKIISFLLPP DESLHSLQSR IERETGISTG SQELLSETGI 360

SLDPRKPASQ CVLDGVRGCD SYMVYLFDKS KTVYEGPFAS RSLSDCVNYI VQDSKIQLPI 420

IQLRKVWAEA VHYVSGLKED YSRLFQGQRA AMLSLLRYNA NLTKMKNTLI SASQQLKAKL 480

EFFHKSIQLD LERYSEQMTY GISSEKMLKA WKEMEEKAIH YAEVGVIGYL EDQIMSLHTE 540

IMELQKSPYG RRQGDLMESL EQRAIDLYKQ LKHRPSDHSY SDSTEMVKII VHTVQSQDRV 600

LKELFGHLSK LLGCKQKIID LLPKVEVALS NIKEADNTVM FMQGKRQKEI WHLLKIACTQ 660

SSARSLVGSS LESAETPQAS AWLPPTSAER EHSLSCVVTP QDGETLAQMI KENLNYLGRV 720

STIIREANEE RGSSMMNLDW SWLTE 745

Nucleotide Sequence
(FASTA)

ATGGAGCGGC CCCCGGGGCT GCGGCCGGGC GCGGGCGGGC CCTGGGAGAT GCGGGAGAGG 60

CTGGGCACTG GCGGCTTCGG GAACGTCTGT CTGTACCAGC ATCGGGAACT TGATCTCAAA 120

GTAGCAATTA AGTCTTGTCG CCTCGAGCTA AGTACCAAAA ACAGAGAACG ATGGTGCCAT 180

GAAATCCAGA TCATGAAGAA GTTGAACCAT ACAAATGTTG TAAAAGCCTG TGATGTTCCT 240

GAAGAACTGA ATATTTTGAT TAATGATGTG CCTCTTCTAG CAATGGAATA CTGTTCTGGA 300

GGTGATCTCC GGAAGTTACT CAACAAACCA GAAAATTGTT GTGGACTTAA AGAAAGCCAG 360

ATACTTTCTT TACTAAGTGA CATAGGGTCT GGGATTCGAT ATTTGCATGA AAACAAAATT 420

ATACATAGAG ATCTAAAACC TGAAAATATA GTTCTTCAGG ATGTTGGTGG AAAGGTAACA 480

CATAAAATAA TTGATCTGGG ATATGCCAAA GATGTTGATC AAGGAAGTCT ATGTACATCG 540

TTTGTGGGGA CATTGCAGTA TCTGGCCCCA GAGCTCTTTG AGAATAAGCC TTACACAGCC 600

ACTGTTGATT ATTGGAGCTT TGGGACCATG GTGTTTGAAT GTATTGCTGG ATATAGGCCT 660

TTTTTGCATC ATCTGCAGCC ATTTACCTGG CATGAGAAGA TTAAGAAGAA GGATCCAAAA 720

TGTATATTTG CATGTGAAGA GATGACAGGA GAAGTTCGGT TTAGTAGTCA TTTGCCCCAA 780

CCAAATAGCC TTTGTAGTTT AATAGTAGAA CCCATGGAGA ACTGGCTACA GTTGATGCTG 840

AATTGGGACC CTCAGCAAAG AGGAGGACCT ATTGATCATA CTTTGAAGCA ACCAAGATGC 900

TTTTTATTAA TGGATCATAT TCTGAATTTG AAGATAGTAC ACATCCTAAA TATGACTTCT 960

GCAAAGATAA TTTCTTTTTT GCTACCACCT GATGAAAGTC TTCATTCACT ACAGTCTCGT 1020

ATTGAGCGTG AAACTGGAAT AAGTACTGGT TCTCAAGAGC TACTTTCAGA GACGGGAATT 1080

TCTCTGGATC CTCGGAAGCC AGCTTCTCAA TGTGTTCTAG ATGGAGTTAG AGGCTGTGAT 1140

AGCTACATGG TTTATTTGTT TGATAAAAGT AAGACTGTAT ATGAAGGGCC ATTTGCTTCA 1200

AGAAGTTTAT CTGATTGTGT AAATTATATT GTACAGGACA GCAAAATACA ACTTCCAATT 1260

ATACAGCTGC GTAAAGTATG GGCTGAAGCC GTGCACTATG TGTCTGGGCT AAAAGAAGAC 1320

TATAGCAGGC TCTTTCAAGG ACAAAGAGCA GCAATGTTAA GTCTGCTTAG ATATAATGCT 1380

AATTTGACAA AAATGAAGAA TACTTTGATC TCAGCATCAC AGCAACTGAA AGCTAAATTG 1440

GAATTTTTTC ACAAAAGCAT TCAGCTTGAC TTGGAGAGAT ATAGTGAGCA GATGACTTAT 1500

GGGATATCTT CAGAAAAAAT GCTAAAAGCA TGGAAAGAAA TGGAAGAAAA GGCCATTCAC 1560

TACGCTGAGG TTGGTGTCAT TGGATACCTG GAGGATCAGA TTATGTCCTT GCACACTGAA 1620

ATCATGGAGC TGCAAAAGAG CCCCTATGGA AGACGCCAGG GAGACTTGAT GGAATCTCTG 1680

GAACAACGAG CCATTGATCT TTATAAGCAG TTAAAGCACA GACCTTCAGA TCACTCCTAC 1740

AGCGACAGCA CAGAGATGGT GAAGATCATT GTGCATACTG TGCAGAGTCA GGATCGTGTT 1800

CTCAAAGAGC TGTTTGGTCA TCTGAGCAAG TTGTTGGGCT GTAAGCAGAA GATTATTGAC 1860

CTACTCCCCA AGGTGGAAGT GGCCCTCAGT AACATCAAAG AAGCTGACAA TACTGTCATG 1920

TTTATGCAGG GAAAGAGGCA GAAAGAAATA TGGCATCTCC TTAAAATTGC TTGTACACAG 1980

AGTTCTGCAC GGTCCCTAGT AGGGTCCAGT CTAGAAAGTG CCGAAACCCC CCAAGCATCA 2040

GCATGGCTGC CCCCAACTTC AGCAGAACGT GAACATTCTC TGTCATGCGT GGTAACTCCT 2100

CAAGATGGGG AGACTTTAGC ACAAATGATA AAAGAAAATT TGAACTATCT TGGCCGTGTA 2160

AGCACTATTA TTCGTGAAGC AAATGAGGAA CGTGGCAGTA GTATGATGAA TCTTGACTGG 2220

AGTTGGTTAA CAGAATGA 2238

Domain Profile

S: 1     WelkelLGeGafgnvikarnkktgekiavkvikeesslrprevqvrelevlrklnhkniv  60

         We++e+LG+G+fgnv+ +++++ + k+a+k+++ e+s+++re++++e+++++klnh+n+v

Q: 15    WEMRERLGTGGFGNVCLYQHRELDLKVAIKSCRLELSTKNRERWCHEIQIMKKLNHTNVV  74

         ************************************************************

S: 61    klvdveeelnlasarlkvlvleyCsgGdlrkvLeepenayGLkesevlvvLsdvvaglry  120

         k++dv+eeln++ +++++l++eyCsgGdlrk+L++pen++GLkes++l++Lsd+ +g+ry

Q: 75    KACDVPEELNILINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRY  134

         ************************************************************

S: 121   LrenkivhRDlkPenivllkgedgksiykltDlGaareldddekvvslvGteeYlaPely  180

         L+enki+hRDlkPenivl+++ +gk  +k++DlG+a+++d++++++s+vGt++YlaPel+

Q: 135   LHENKIIHRDLKPENIVLQDV-GGKVTHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELF  193

         ********************9.**************************************

S: 181   eqkkytatvDlWsiGvllyeaitGslPflpfegprrlykkitkkpakaiagtekangeve  240

         e+k ytatvD+Ws+G++++e+i+G++Pfl++ +p+++++ki+kk++k+i+++e+++gev+

Q: 194   ENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMTGEVR  253

         ************************************************************

S: 241   fssslPlsaslssglqeklekllanllevdeekrw  275

         fss+lP+++sl+s+++e +e++l+++l++d+++r+

Q: 254   FSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRG  288

         ********************************986

Domain Sequence
(FASTA)

WEMRERLGTG GFGNVCLYQH RELDLKVAIK SCRLELSTKN RERWCHEIQI MKKLNHTNVV 60

KACDVPEELN ILINDVPLLA MEYCSGGDLR KLLNKPENCC GLKESQILSL LSDIGSGIRY 120

LHENKIIHRD LKPENIVLQD VGGKVTHKII DLGYAKDVDQ GSLCTSFVGT LQYLAPELFE 180

NKPYTATVDY WSFGTMVFEC IAGYRPFLHH LQPFTWHEKI KKKDPKCIFA CEEMTGEVRF 240

SSHLPQPNSL CSLIVEPMEN WLQLMLNWDP QQRG 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>