EKS-OTG-00096

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00096

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.2	3.1E-133	2153	2477	325

Status

Unreviewed

Ensembl Protein

ENSOGAP00000012253

UniProt Accession

H0X9K8;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000013669	ENSOGAP00000012253	ENSOGAT00000013683

Organism

Otolemur garnettii

Functional Description

Protein Length

2549

Protein Sequence
(FASTA)

MLGTGPAAAT TTTVTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFEVK RALEWLGADR NEGRRHAAVL VLRELAISVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPQQSNAL VGLLGYSSHQ GLMGFGASPS PAKSTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPGIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPGL TTLPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSIHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR IVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEVPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR STAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD VLICRIVKGY TLADEEEDPL IYHHRMLRSS QGDALASGPV ETGPMKKLHV 1260

STINLQKAWG AARRVSKDDW LEWLRRLSLE LLKDSSSPSL RSCWALAQAY NPMARDLFNA 1320

AFVSCWSELN EDQQDELIRS IELALTSQDI AEVTQTLLNL AEFMEHSDKG PLPLRDDNGI 1380

VLLGERAAKC RAYAKALHYK ELEFQKGPTP AILESLISIN NKLQQPEAAA GVLEYAMKHF 1440

GELEIQATWY EKLHEWEDAL VAYDKKMDTN KDDPELMLGR MRCLEALGEW GQLHQQCCEK 1500

WTLVNDETQA KMARMAAAAA WGLGQWDSME EYTCMIPRDT HDGAFYRAVL ALHQDLFSLA 1560

QQCIDKARDL LDAELTAMAG ESYSRAYGAM VSCHMLSELE EVIQYKLVPE RREIIRQIWW 1620

ERLQGCQRIV EDWQKILMVR SLVVSPHEDM RTWLKYASLC GKSGRLALAH KTLVLLLGVD 1680

PSRQLDHPLP TVHPQVTYAY MKNMWKSARK IDAFQHMQHF VQTMQQQAQH AIATEDQQHK 1740

QELHKLMARC FLKLGEWQLN LQGINESTIP KVLQYYSAAT EHDRSWYKAW HAWAVMNFEA 1800

VLHYKHQNQA RDEKKKLRHA SGANITSATT AATTAATAAA AASTEGSNSE SEAESTESSP 1860

SPSPLQKKVT EDLSKTLLMY TVPAVQGFFR SISLSRGNNL QDTLRVLTLW FDYGHWPDVN 1920

EALVEGVKAI QIDTWLQVIP QLIARIDTPR PLVGRLIHQL LTDIGRYHPQ ALIYPLTVAS 1980

KSTTTARHNA ANKILKNMCE HSNTLVQQAM MVSEELIRVA ILWHEMWHEG LEEASRLYFG 2040

ERNVKGMFEV LEPLHAMMER GPQTLKETSF NQAYGRDLME AQEWCRKYMK SGNVKDLTQA 2100

WDLYYHVFRR ISKQLPQLTS LELQYVSPKL LMCRDLELAV PGTYDPNQPI IRIQSIAPSL 2160

QVITSKQRPR KLTLMGSNGH EFVFLLKGHE DLRQDERVMQ LFGLVNTLLA NDPTSLRKNL 2220

SIQRYAVIPL STNSGLIGWV PHCDTLHALI RDYREKKKIL LNIEHRIMLR MAPDYDHLTL 2280

MQKVEVFEHA VNNTAGDDLA KLLWLKSPSS EVWFDRRTNY TRSLAVMSMV GYILGLGDRH 2340

PSNLMLDRLS GKILHIDFGD CFEVAMTREK FPEKIPFRLT RMLTNAMEVT GLDGNYRITC 2400

HTVMEVLREH KDSVMAVLEA FVYDPLLNWR LMDTNTKGNK RSRTRTDSYS AGQSVEILDG 2460

VELGEPAHKK TGTTVPESIH SFIGDGLVKP EALNKKAIQI INRVRDKLTG RDFSHDDTLD 2520

VPTQVELLIK QATSHENLCQ CYIGWCPFW 2549

Nucleotide Sequence
(FASTA)

ATGCTTGGGA CCGGGCCTGC CGCCGCCACC ACCACTACCG TCACATCTAG CAATGTGAGT 60

GTTCTGCAGC AGTTCGCCAG TGGCCTGAAG AGTCGGAATG AGGAGACCAG AGCCAAAGCT 120

GCCAAGGAGC TCCAGCACTA TGTCACCATG GAGCTTCGAG AGATGAGCCA AGAGGAATCC 180

ACTCGCTTTT ATGATCAGCT GAACCATCAC ATTTTTGAAC TGGTTTCCAG CTCAGATGCT 240

AATGAGAGGA AAGGGGGCAT CTTGGCCATA GCCAGCCTCA TAGGAGTGGA AGGTGGGAAT 300

GCCACCCGAA TTGGCAGGTT TGCCAACTAT CTTCGGAACC TCCTCCCCTC CAATGACCCA 360

GTTGTCATGG AAATGGCATC CAAGGCGATT GGCCGCCTTG CCATGGCCGG GGACACTTTC 420

ACAGCAGAGT ACGTGGAGTT CGAGGTGAAG CGAGCCCTGG AATGGCTGGG TGCTGACCGC 480

AACGAGGGCC GCAGACATGC AGCCGTCCTG GTTCTCCGTG AGCTGGCCAT CAGCGTCCCC 540

ACCTTCTTCT TCCAGCAAGT GCAACCCTTC TTTGACAACA TCTTTGTGGC TGTGTGGGAC 600

CCCAAGCAGG CCATCCGCGA GGGAGCTGTG GCCGCCCTTC GTGCTTGTCT GATTCTCACC 660

ACCCAGCGTG AGCCGAAGGA GATGCAGAAG CCCCAGTGGT ACAGGCACAC ATTTGAAGAA 720

GCAGAGAAAG GGTTTGATGA AACCTTGGCC AAAGAGAAGG GCATGAATCG GGATGATCGG 780

ATCCACGGAG CCTTGCTGAT CCTCAACGAG CTGGTCCGGA TCAGCAGCAT GGAGGGAGAG 840

CGTTTGAGAG AAGAAATGGA GGAAATCACA CAGCAGCAGC TGGTGCATGA CAAGTACTGC 900

AAAGATCTCA TGGGCTTTGG AACGAAACCT CGTCACATTA CCCCCTTCAC CAGTTTCCAG 960

GCTGTCCAGC CCCAGCAGTC AAATGCCTTG GTGGGGCTGC TGGGGTACAG CTCTCACCAG 1020

GGCCTCATGG GATTTGGGGC TTCCCCCAGC CCAGCGAAGT CCACTCTGGT GGAGAGTCGG 1080

TGCTGCAGGG ACTTGATGGA GGAGAAATTC GATCAGGTGT GCCAGTGGGT GCTGAAATGC 1140

AGAAATAGCA AGAACTCACT GATCCAAATG ACAATCCTTA ATTTGCTGCC CCGTTTGGCT 1200

GCATTCCGGC CTTCTGCATT CACAGATACC CAGTACCTCC AAGATACCAT GAACCACGTC 1260

CTAAGCTGTG TCAAGAAGGA GAAGGAACGT ACTGCAGCCT TCCAAGCCCT GGGGCTACTT 1320

TCAGTGGCTG TAAGGTCTGA GTTTAAGGTC TATTTGCCTC GTGTGCTGGA CATCATCCGG 1380

GCAGCCCTGC CCCCTAAGGA CTTCGCCCAT AAGAGGCAGA AGGCAATGCA GGTGGATGCC 1440

ACAGTGTTCA CATGCATTAG CATGCTGGCA CGAGCAATGG GGCCGGGCAT CCAGCAGGAC 1500

ATCAAGGAGC TGCTGGAGCC CATGCTGGCG GTCGGCCTAA GCCCTGCCCT CACTGCTGTG 1560

CTCTACGACC TGAGCCGTCA GATTCCACAG CTGAAGAAGG ACATCCAAGA CGGGCTTCTG 1620

AAAATGCTAT CCCTGGTCCT TATGCACAAA CCCCTCCGGC ACCCAGGCAT GCCCAAGGGC 1680

CTGGCCCATC AGTTGGCCTC CCCCGGCCTC ACAACCCTTC CTGAGGCCAG TGATGTGGGC 1740

AGTATCACTC TTGCCCTCCG AACCCTTGGC AGCTTTGAAT TTGAAGGCCA CTCTCTGACC 1800

CAGTTTGTCC GCCACTGTGC GGATCATTTC CTGAACAGTG AACACAAGGA GATCCGCATG 1860

GAAGCTGCCC GCACCTGCTC TCGCCTGCTC ACGCCCTCCA TCCACCTCAT CAGTGGCCAC 1920

GCTCACGTGG TTAGCCAGAC TGCAGTGCAA GTGGTGGCAG ATGTGCTCAG CAAACTGCTC 1980

GTGGTTGGGA TAACAGACCC TGACCCCGAT ATTCGCTACT GCGTCTTGGC ATCCCTGGAT 2040

GAGCGCTTTG ATGCACACCT GGCCCAAGCA GAGAACTTGC AGGCCCTGTT TGTGGCCCTG 2100

AATGACCAAG TATTTGAGAT CCGGGAGCTG GCCATCTGCA CTGTGGGCCG ACTCAGTAGC 2160

ATGAACCCAG CCTTTGTCAT GCCTTTCCTG CGCAAGATGC TTATCCAGAT TTTGACAGAG 2220

CTGGAGCACA GTGGGATTGG AAGAATCAAA GAGCAAAGTG CCCGCATGCT GGGGCACCTG 2280

GTCTCTAATG CGCCCCGCCT CATCCGCCCC TACATGGAGC CTATTCTGAA GGCTTTGATT 2340

TTGAAACTGA AAGATCCAGA CCCTGATCCA AACCCAGGTG TGATCAATAA TGTCTTGGCT 2400

ACAATAGGAG AATTGGCTCA GGTTAGTGGC CTGGAAATGA GGAAATGGGT TGATGAACTT 2460

TTTATTATTA TCATGGACAT GCTTCAAGAT TCTTCTCTAT TGGCCAAAAG GCAGGTGGCT 2520

CTGTGGACCC TGGGACAGTT GGTGGCCAGC ACTGGCTATG TGGTCGAGCC CTACAGGAAG 2580

TACCCTACTT TGCTTGAGGT GCTACTGAAT TTTCTGAAGA CCGAGCAGAA CCAGGGCACA 2640

CGGCGAGAGG CCATCCGTGT ATTAGGGCTT TTGGGGGCTT TGGATCCCTA CAAGCACAAA 2700

GTGAACATTG GCATGATTGA CCAGTCCCGG GATGCCTCCG CGGTCAGCCT GTCAGAATCC 2760

AAGTCAAGTC AGGATTCCTC TGACTACAGC ACCAGTGAAA TGCTGGTCAA CATGGGAAAC 2820

CTGCCCCTGG ATGAGTTCTA CCCGGCTGTG TCCATGGTGG CCCTGATGCG GATCTTCCGA 2880

GACCAGTCCC TCTCTCATCA TCACACCATG GTTGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCACTGGGAC TCAAGTGTGT GCAGTTCCTG CCCCAGGTCA TGCCCACGTT CCTTAACGTC 3000

ATTCGGGTCT GTGATGGGGC CATCCGGGAA TTTTTGTTCC AGCAGCTGGG AATGCTGGTG 3060

TCCTTTGTGA AGAGCCACAT CAGACCTTAC ATGGATGAAA TAGTCACCCT CATGAGAGAA 3120

TTCTGGGTCA TGAACACCTC CATCCAGAGC ACAATCATTC TTCTCATTGA GCAAATTGTG 3180

GTAGCTCTTG GGGGTGAATT TAAACTCTAC CTGCCGCAGC TGATCCCACA TATGCTGCGG 3240

GTCTTTATGC ATGACAACAG CCCAGGCCGC ATTGTCTCCA TCAAGTTGTT GGCTGCGATC 3300

CAGCTGTTTG GTGCCAACCT GGATGACTAT TTGCATTTGC TGTTGCCACC TATTGTGAAG 3360

TTGTTTGATG CCCCCGAAGT TCCACTGCCT TCTCGAAAGG CAGCGTTAGA GACAGTGGAC 3420

CGCCTGACGG AGTCTCTGGA TTTCACTGAC TATGCCTCCC GAATCATTCA CCCTATTGTT 3480

CGAACACTGG ATCAGAGCCC AGAACTGCGT TCCACAGCCA TGGACACATT GTCTTCACTT 3540

GTCTTTCAGC TGGGGAAGAA GTACCAAATT TTCATTCCAA TGGTGAATAA AGTTCTGGTG 3600

CGACATCGAA TCAACCATCA GCGCTATGAT GTGCTCATCT GCAGAATTGT CAAGGGATAC 3660

ACCCTTGCTG ATGAAGAGGA GGACCCTTTG ATTTACCATC ATCGAATGCT TAGGAGCAGC 3720

CAAGGGGATG CATTGGCTAG TGGACCAGTA GAAACAGGAC CCATGAAGAA ACTGCACGTC 3780

AGCACCATCA ACCTCCAGAA GGCCTGGGGA GCAGCCAGGA GGGTCTCCAA GGATGACTGG 3840

CTGGAGTGGC TGAGAAGGCT GAGCCTGGAG CTGCTGAAGG ACTCCTCATC CCCCTCCCTG 3900

CGATCCTGCT GGGCCTTGGC ACAGGCCTAC AACCCAATGG CCAGGGATCT CTTCAATGCT 3960

GCATTTGTGT CCTGCTGGTC TGAACTGAAT GAAGACCAGC AGGATGAGCT CATCAGAAGC 4020

ATCGAGTTGG CCCTCACCTC TCAGGACATC GCTGAAGTCA CACAAACCCT CTTAAACTTG 4080

GCTGAATTCA TGGAACACAG TGACAAGGGC CCCCTGCCAC TGAGAGACGA CAATGGCATT 4140

GTTCTGCTGG GTGAAAGAGC TGCCAAGTGC CGAGCATATG CCAAAGCACT ACACTATAAA 4200

GAACTGGAGT TCCAGAAAGG TCCCACCCCT GCCATTCTAG AATCTCTCAT CAGCATTAAC 4260

AATAAGCTAC AGCAGCCGGA GGCAGCTGCC GGGGTGTTAG AATATGCCAT GAAACACTTT 4320

GGAGAGCTGG AGATCCAGGC TACCTGGTAT GAGAAACTGC ACGAGTGGGA GGATGCTCTT 4380

GTAGCCTATG ATAAGAAGAT GGACACCAAC AAGGATGACC CAGAGCTGAT GCTGGGCCGC 4440

ATGCGCTGCC TCGAGGCCTT GGGTGAATGG GGACAGCTCC ACCAGCAGTG CTGTGAAAAG 4500

TGGACCCTGG TTAATGATGA GACCCAAGCC AAGATGGCCC GGATGGCTGC TGCAGCTGCC 4560

TGGGGTTTGG GTCAGTGGGA CAGCATGGAA GAGTACACCT GTATGATCCC TCGGGACACC 4620

CATGACGGGG CATTCTACAG AGCTGTGCTG GCACTACATC AAGACCTCTT CTCCTTGGCA 4680

CAACAGTGCA TCGACAAGGC CAGGGACCTG CTGGATGCTG AGTTAACTGC GATGGCAGGA 4740

GAGAGCTACA GTCGGGCATA TGGGGCCATG GTTTCTTGCC ACATGCTGTC CGAGCTGGAG 4800

GAGGTTATCC AGTACAAACT CGTCCCTGAG CGACGAGAGA TCATCCGCCA GATCTGGTGG 4860

GAAAGATTGC AGGGCTGCCA ACGTATTGTA GAAGACTGGC AGAAAATCCT TATGGTGCGA 4920

TCCCTTGTGG TCAGCCCTCA TGAGGACATG AGGACCTGGC TCAAGTATGC AAGTCTATGT 4980

GGCAAGAGTG GCAGGCTGGC TCTTGCTCAT AAAACCTTAG TATTGCTCCT GGGAGTTGAT 5040

CCATCTCGGC AACTTGACCA TCCTCTGCCG ACCGTTCACC CTCAGGTGAC CTATGCCTAC 5100

ATGAAGAATA TGTGGAAGAG CGCTCGCAAG ATCGATGCCT TCCAGCACAT GCAGCACTTT 5160

GTCCAGACCA TGCAGCAGCA GGCCCAGCAC GCCATCGCCA CTGAGGACCA GCAGCACAAA 5220

CAGGAGCTGC ACAAGCTCAT GGCCCGATGC TTCCTGAAAC TTGGGGAGTG GCAGCTGAAC 5280

CTACAGGGCA TCAACGAGAG CACAATCCCC AAAGTGCTGC AGTACTACAG CGCAGCCACG 5340

GAGCACGACC GCAGCTGGTA CAAGGCCTGG CACGCATGGG CAGTGATGAA CTTTGAAGCT 5400

GTACTGCACT ACAAACATCA GAACCAAGCC CGGGACGAGA AGAAGAAACT GCGTCATGCC 5460

AGTGGAGCCA ACATCACCAG TGCCACCACT GCTGCCACCA CAGCTGCCAC TGCTGCTGCT 5520

GCGGCCAGCA CCGAGGGCAG CAACAGCGAG AGCGAGGCTG AGAGCACAGA GAGCAGCCCC 5580

AGCCCTTCTC CTCTGCAGAA GAAGGTCACC GAGGATCTGT CCAAAACCCT CCTGATGTAC 5640

ACTGTTCCCG CAGTTCAGGG CTTCTTCCGT TCCATCTCCT TGTCTCGAGG CAACAACCTC 5700

CAGGATACAC TCAGAGTCCT CACCTTATGG TTTGATTATG GTCACTGGCC AGATGTCAAC 5760

GAAGCCTTGG TGGAAGGTGT GAAAGCCATC CAGATCGACA CTTGGTTACA GGTTATACCT 5820

CAGCTCATTG CAAGAATCGA TACACCCAGA CCCTTGGTGG GACGCCTCAT TCATCAGCTT 5880

CTCACAGACA TTGGTCGGTA CCACCCCCAG GCCCTCATCT ACCCCCTGAC TGTGGCTTCT 5940

AAGTCCACCA CCACAGCCCG GCACAATGCG GCCAACAAGA TCCTGAAGAA CATGTGTGAG 6000

CACAGTAACA CGCTGGTCCA GCAGGCCATG ATGGTGAGTG AGGAGCTGAT CCGAGTGGCC 6060

ATCCTCTGGC ATGAGATGTG GCATGAAGGC CTGGAAGAGG CATCTCGCTT GTATTTTGGG 6120

GAGAGGAATG TGAAAGGCAT GTTCGAGGTG CTGGAGCCTC TGCATGCTAT GATGGAACGG 6180

GGCCCCCAGA CCCTGAAGGA AACGTCCTTT AATCAGGCAT ATGGTCGAGA TTTAATGGAG 6240

GCCCAGGAGT GGTGCAGAAA GTACATGAAA TCAGGGAATG TCAAGGACCT CACCCAAGCC 6300

TGGGACCTCT ATTACCATGT GTTCAGACGG ATCTCCAAAC AGCTGCCTCA GCTCACATCC 6360

TTGGAGCTGC AGTATGTTTC TCCAAAACTT TTAATGTGCC GGGACCTTGA ATTGGCTGTG 6420

CCAGGAACCT ATGACCCCAA CCAGCCAATC ATTCGCATTC AGTCCATAGC ACCGTCTTTG 6480

CAAGTCATCA CGTCCAAGCA GAGGCCCCGG AAGTTGACAC TGATGGGCAG CAACGGGCAT 6540

GAGTTTGTTT TCCTCCTGAA AGGCCATGAA GATCTGAGGC AGGACGAGCG GGTGATGCAG 6600

CTCTTTGGCC TGGTTAACAC CCTTCTGGCC AATGACCCAA CATCTCTTCG GAAAAACCTC 6660

AGCATCCAGA GGTACGCCGT CATCCCTTTG TCAACCAACT CCGGCCTCAT TGGCTGGGTC 6720

CCCCACTGTG ACACGCTGCA TGCCCTGATC CGGGACTACA GGGAGAAAAA GAAGATCCTT 6780

CTGAACATCG AGCATCGCAT CATGCTGCGG ATGGCCCCAG ACTATGACCA CTTGACTCTG 6840

ATGCAGAAGG TGGAGGTGTT TGAGCACGCC GTCAATAACA CAGCTGGGGA CGACCTGGCC 6900

AAGCTGCTGT GGCTCAAAAG CCCCAGCTCC GAGGTGTGGT TTGACCGAAG AACCAATTAT 6960

ACACGCTCTT TAGCGGTCAT GTCAATGGTT GGGTATATTT TGGGCCTGGG AGATAGACAC 7020

CCATCCAACC TGATGCTGGA CCGGCTGAGT GGGAAGATCC TGCACATTGA CTTTGGGGAC 7080

TGCTTTGAGG TTGCTATGAC CAGAGAGAAG TTTCCAGAGA AGATTCCATT CAGACTAACA 7140

AGAATGTTGA CCAATGCTAT GGAGGTTACC GGCCTGGATG GCAACTACAG AATCACATGC 7200

CACACGGTGA TGGAAGTGCT TCGGGAACAC AAGGACAGTG TCATGGCTGT GCTGGAAGCC 7260

TTTGTCTATG ACCCCTTGCT AAACTGGAGG CTAATGGATA CAAATACCAA AGGCAACAAA 7320

CGATCCCGGA CGAGGACCGA TTCCTACTCT GCTGGCCAGT CAGTAGAAAT TTTGGATGGT 7380

GTGGAACTTG GGGAACCAGC CCATAAGAAA ACAGGGACCA CAGTGCCAGA ATCCATTCAT 7440

TCCTTCATTG GAGACGGTTT GGTGAAACCA GAGGCCCTAA ATAAGAAAGC TATTCAGATT 7500

ATCAACAGAG TTCGAGATAA GCTTACTGGC CGGGACTTCT CGCATGACGA TACTTTGGAT 7560

GTTCCAACAC AAGTCGAGCT GCTCATCAAA CAAGCAACAT CCCATGAAAA CCTCTGCCAG 7620

TGCTACATCG GCTGGTGCCC TTTCTGGTAA 7650

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2153  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2212

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2213  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2265

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2266  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2324

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+++

Q: 2325  AVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLT  2384

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2385  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2444

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2445  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2477

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDRHPS NLMLDRLSGK ILHIDFGDCF EVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013