EKS-OTG-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	514.6	5.0E-155	4	287	284

Status

Unreviewed

Ensembl Protein

ENSOGAP00000012814

UniProt Accession

H0XAY3;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000014294	ENSOGAP00000012814	ENSOGAT00000014302

Organism

Otolemur garnettii

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

MEKYEKIRKI GEGSYGDVFK CRNRDTGQIV AIKRFLESED DPVIKKIAHR EIRMLKQLKH 60

PNLVTLLEVF RRKRRLHLVF EYCDRTVLHE LDRYQRGVPE HLVKSITWQT LQAVNFCHKH 120

NCIHRDVKPE NILITKHSVI KLCDFGFARL LTGPSDCYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGAP LWPGKSDVDQ LYLIRKTLGD LIPRHQQVFS TNQYFSGVKI 240

PDPEDMEPLE LKFPNFSYPA LEVLKGCLHM DPGERLACEQ LLKHPYFDSI REIGDLAKEH 300

DKPTWKTLKY SQKHLPRVKV MHCFTETSKL QHLPQLTSGS ILPALNDKKY YSHTKKLNYR 360

FPNI 364

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ATGAGAAAAT TAGGAAAATT GGAGAAGGAT CCTACGGAGA TGTTTTCAAA 60

TGTAGGAACA GGGACACGGG TCAAATTGTG GCCATAAAGA GGTTTCTGGA ATCCGAAGAC 120

GACCCAGTCA TCAAGAAGAT CGCCCACCGG GAAATCCGCA TGCTCAAGCA ACTCAAGCAC 180

CCCAACCTGG TCACCCTCCT GGAGGTCTTC AGGAGGAAAC GGAGGCTCCA CCTGGTGTTT 240

GAATATTGTG ACCGCACAGT TCTCCACGAA TTGGACAGAT ACCAACGAGG GGTACCAGAA 300

CATCTCGTGA AGAGCATAAC TTGGCAGACG CTGCAAGCTG TAAACTTTTG CCACAAACAC 360

AACTGTATAC ATAGAGATGT AAAGCCAGAA AATATTCTCA TCACAAAACA TTCAGTGATT 420

AAGCTTTGCG ACTTTGGATT TGCCCGGCTT TTGACTGGAC CAAGTGACTG CTACACAGAC 480

TATGTGGCTA CCAGGTGGTA CCGCTCCCCG GAACTGCTGG TGGGTGACAC ACAGTACGGC 540

CCCCCAGTAG ATGTTTGGGC AATTGGCTGT GTCTTTGCTG AGCTGCTATC AGGAGCGCCT 600

CTGTGGCCAG GAAAGTCAGA TGTGGACCAG CTGTACCTGA TTAGGAAAAC CCTGGGAGAT 660

CTCATCCCTA GGCACCAGCA AGTATTTAGC ACAAATCAGT ACTTCAGCGG GGTGAAAATT 720

CCAGATCCTG AAGATATGGA ACCACTTGAA TTAAAGTTTC CAAACTTCTC TTATCCTGCC 780

CTGGAGGTCT TAAAGGGCTG TCTCCACATG GACCCTGGCG AGAGACTGGC CTGTGAACAG 840

CTGTTGAAGC ACCCTTATTT TGACAGCATC AGAGAAATAG GAGATTTGGC AAAAGAACAT 900

GACAAACCAA CATGGAAGAC CCTAAAATAC AGCCAAAAGC ACCTGCCGAG GGTAAAAGTG 960

ATGCACTGTT TTACAGAAAC ATCCAAGTTG CAGCACCTCC CTCAGCTAAC GAGCGGCAGC 1020

ATCCTTCCAG CTTTGAATGA CAAGAAGTAC TACTCTCATA CCAAGAAACT TAACTACCGT 1080

TTTCCAAACA TTTAA 1095

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+ k+GeGsyG v+kcrn+dtgqivaik+flesedd+++kkia rei++lkqlkh+nl

Q: 4     YEKIRKIGEGSYGDVFKCRNRDTGQIVAIKRFLESEDDPVIKKIAHREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v llevfrrk++l+lvfey+d+tvl+el+ry++Gv+e+lvk+i++q+l+a++fchk+n+i

Q: 64    VTLLEVFRRKRRLHLVFEYCDRTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfarll++p+d ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILITKHSVIKLCDFGFARLLTGPSDCYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+irktlG+liprhq++fs+n++f+Gvk+p++

Q: 184   DVWAIGCVFAELLSGAPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le k+p+ ++ +l++lk+cl++dp erl+ce+llkh+yf

Q: 244   EDMEPLELKFPNFSYPALEVLKGCLHMDPGERLACEQLLKHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIRKIGEG SYGDVFKCRN RDTGQIVAIK RFLESEDDPV IKKIAHREIR MLKQLKHPNL 60

VTLLEVFRRK RRLHLVFEYC DRTVLHELDR YQRGVPEHLV KSITWQTLQA VNFCHKHNCI 120

HRDVKPENIL ITKHSVIKLC DFGFARLLTG PSDCYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGAPLWP GKSDVDQLYL IRKTLGDLIP RHQQVFSTNQ YFSGVKIPDP 240

EDMEPLELKF PNFSYPALEV LKGCLHMDPG ERLACEQLLK HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013