EKS-OTG-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	526.7	1.1E-158	24	291	268

Status

Unreviewed

Ensembl Protein

ENSOGAP00000012888

UniProt Accession

H0XB43;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000014382	ENSOGAP00000012888	ENSOGAT00000014387

Organism

Otolemur garnettii

Functional Description

Protein Length

406

Protein Sequence
(FASTA)

MTLDVGPEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGQEF AVKIMEVTAE 60

RLSPEQLEEV REATRRETHI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT 120

EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDSMQIRLS DFGFSCHLEP 180

GEKLRELCGT PGYLAPEILK CSMDETHPGY GKEVDLWACG VILFTLLAGS PPFWHRRQIL 240

MLRMIMEGQY QFSSPEWDDR SNTVKDLISR LLQVDPEERL TAEQALQHPF FERCEGSQPW 300

NLTPRQRFRV AVWTVLAAGR VALSTHRVRP LTKSALLRDP YALRSVRRLI DNCAFRLYGH 360

WVKKGEQQNR AALFQHRPPG PFPIMGPEEE GDSTTVPEDE AAVVLG 406

Nucleotide Sequence
(FASTA)

ATGACGCTGG ACGTGGGGCC GGAGGATGAG CTGCCCGACT GGGCCGCGGC CAAGGAGTTT 60

TACCAGAAGT ACGACCCTAA GGACGTCATT GGCAGAGGAG TGAGCTCTGT GGTCCGTCGT 120

TGTGTTCATC GAGCTACGGG CCAGGAGTTT GCAGTGAAGA TCATGGAGGT GACAGCTGAG 180

CGGCTGAGTC CTGAGCAGCT GGAGGAGGTG CGAGAAGCCA CACGGCGAGA GACACACATC 240

CTTCGCCAGG TCGCTGGCCA CCCCCACATC ATCACTCTCA TCGATTCCTA CGAGTCTTCT 300

AGCTTCATGT TCCTGGTGTT TGACCTGATG CGGAAGGGAG AGCTGTTTGA CTATCTGACA 360

GAGAAGGTGG CCCTCTCAGA AAAGGAAACC AGGTCCATTA TGAGGTCTCT GCTGGAAGCT 420

GTGAGCTTTC TCCATGCCAA CAACATTGTG CACCGAGACT TGAAGCCTGA GAATATTCTC 480

CTAGATGACA GTATGCAGAT CCGACTTTCA GATTTTGGGT TCTCCTGCCA CTTGGAACCT 540

GGCGAGAAGC TTCGAGAGTT GTGTGGGACC CCAGGGTATC TGGCACCAGA GATCCTTAAA 600

TGCTCGATGG ATGAAACCCA CCCAGGCTAT GGCAAGGAGG TCGACCTCTG GGCCTGTGGG 660

GTGATCTTGT TCACACTCCT GGCTGGCTCA CCACCCTTCT GGCACCGGCG CCAGATCCTG 720

ATGTTACGTA TGATCATGGA GGGCCAGTAC CAGTTTAGTT CACCCGAGTG GGACGACCGT 780

TCAAACACTG TCAAAGACCT GATCTCCAGG CTGCTGCAGG TTGATCCTGA GGAACGCCTG 840

ACAGCTGAAC AGGCCTTACA GCATCCCTTC TTTGAGCGTT GTGAAGGCAG CCAACCCTGG 900

AACCTAACCC CCCGCCAGCG GTTCCGGGTT GCAGTGTGGA CAGTGCTGGC TGCTGGACGA 960

GTGGCCTTAA GCACCCATCG TGTACGTCCA CTGACCAAGA GTGCACTGTT GAGGGATCCT 1020

TACGCACTGC GGTCAGTGCG ACGCCTCATC GACAACTGTG CCTTCCGGCT CTATGGACAC 1080

TGGGTGAAGA AAGGCGAGCA GCAGAACCGA GCAGCCCTCT TTCAGCACCG GCCCCCTGGG 1140

CCTTTTCCCA TAATGGGCCC TGAAGAAGAG GGGGACTCAA CTACTGTACC TGAGGACGAA 1200

GCTGCAGTGG TGCTGGGCTA G 1221

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pk+++GrGvssvvrrc+++atgqefavki++v+ae+ls+e+++e+reat++e++ilrq

Q: 24    YDPKDVIGRGVSSVVRRCVHRATGQEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQ  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v+Ghp+ii+l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++

Q: 84    VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha+nivhrdlkpenilldd ++i+lsdfGfs++le+GeklrelcGtpgylapeilkcsm

Q: 144   LHANNIVHRDLKPENILLDDSMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++pGy+kevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++

Q: 204   DETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+ll+vdpe+rltae+al+hpff

Q: 264   VKDLISRLLQVDPEERLTAEQALQHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKDVIGRG VSSVVRRCVH RATGQEFAVK IMEVTAERLS PEQLEEVREA TRRETHILRQ 60

VAGHPHIITL IDSYESSSFM FLVFDLMRKG ELFDYLTEKV ALSEKETRSI MRSLLEAVSF 120

LHANNIVHRD LKPENILLDD SMQIRLSDFG FSCHLEPGEK LRELCGTPGY LAPEILKCSM 180

DETHPGYGKE VDLWACGVIL FTLLAGSPPF WHRRQILMLR MIMEGQYQFS SPEWDDRSNT 240

VKDLISRLLQ VDPEERLTAE QALQHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013