EKS-OTG-00214

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00214

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	481.6	5.7E-145	4	286	283

Status

Unreviewed

Ensembl Protein

ENSOGAP00000014581

UniProt Accession

H0XF17;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000016285	ENSOGAP00000014581	ENSOGAT00000016292

Organism

Otolemur garnettii

Functional Description

Protein Length

592

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKETGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIDYLHGNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL TPHLQNIFST SPIFAGVVLP 240

QVQHLKNARK KYPKLNGLLA DIVHACLQID PAERISSTDL LNHEYFTRDG FIEKFIPELR 300

AKLLQEAKVN SFIKPKENCK ENELMRDERK TMYTNTLLSS SVGGKETEKE KRPKDIKVRF 360

TKVRGGKGDI SEPKKTEYES RYCQQDAIEN AHAISEDIKP VFIEPPNPVN PSTNSNDMKE 420

NLHSGGCMTM PPINLTSGNL MAANLSSTLP HSNIRLTERA KKRRTSSQSI GQAIYNGRQE 480

DAGPTQSQME KGIFNERTGQ SDQMANENKR KLNFSRTDRK EFHFPELPFT IQSKDIKGME 540

AKQTKVLKRD SKKTDSSKIP TLLNMDQNQE KQEGGDGHCE GKNLKRNRFF FW 592

Nucleotide Sequence
(FASTA)

ATGGAGATGT ACGAAACCCT TGGAAAAGTG GGAGAGGGAA GTTACGGAAC AGTCATGAAA 60

TGTAAACACA AGGAAACGGG ACAGATAGTG GCCATTAAGA TATTTTATGA GAAACCAGAA 120

AAGTCTGTCA ACAAAATTGC AACAAGAGAA ATAAAGTTTC TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATTTGATTGA AGTTTTTAGA CAGAAGAAGA AAATTCATTT AGTATTTGAA 240

TTTATTGACC ACACAGTATT AGATGAGTTA CAGCATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA AATATCTCTT CCAGATCCTT CGAGCAATTG ACTATCTTCA TGGTAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACAAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACACTA GCAGCTCCAG GGGACATTTA TACGGATTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACTTC TTATGGAAAA 540

CCTGTGGATA TTTGGGCTTT GGGCTGTATG ATCATTGAAA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGCA GCTCTGATTT GGATTTACTC CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCACT TGCAGAATAT CTTTTCTACA AGTCCCATTT TTGCTGGGGT GGTCCTTCCT 720

CAAGTTCAAC ATCTCAAAAA TGCAAGAAAA AAATACCCAA AGCTTAATGG ATTGTTGGCA 780

GATATAGTTC ATGCTTGTTT ACAAATTGAT CCTGCTGAGA GGATATCATC TACTGATCTT 840

TTGAATCATG AGTATTTTAC CAGGGATGGA TTTATTGAAA AATTCATACC AGAACTAAGA 900

GCTAAATTAC TACAGGAAGC AAAAGTCAAT TCATTCATCA AGCCAAAAGA AAATTGTAAA 960

GAAAATGAAC TTATGAGAGA TGAAAGAAAA ACAATGTATA CCAATACACT GCTAAGTAGC 1020

TCAGTAGGGG GAAAGGAAAC AGAAAAAGAG AAAAGGCCCA AGGATATCAA AGTCAGATTT 1080

ACTAAAGTCA GAGGAGGAAA AGGAGATATC TCAGAACCGA AAAAGACAGA GTATGAAAGT 1140

CGATATTGTC AACAAGATGC AATTGAAAAT GCTCATGCTA TATCTGAAGA TATAAAACCT 1200

GTATTCATTG AACCACCAAA CCCTGTCAAT CCTAGCACTA ATTCTAATGA TATGAAAGAA 1260

AATCTGCATT CTGGAGGTTG TATGACAATG CCACCCATCA ATCTAACTAG TGGTAATCTG 1320

ATGGCTGCAA ATCTCAGTTC AACTCTCCCT CACTCTAATA TAAGGTTAAC TGAAAGAGCA 1380

AAAAAGAGAC GTACTTCTTC GCAATCAATT GGACAAGCTA TATATAATGG CAGGCAAGAG 1440

GATGCAGGTC CCACTCAAAG CCAAATGGAA AAGGGTATAT TTAATGAGCG AACAGGTCAA 1500

AGTGATCAAA TGGCAAATGA GAACAAAAGG AAGCTGAATT TTTCCAGAAC TGACAGGAAA 1560

GAATTCCATT TTCCAGAATT GCCTTTTACA ATACAGTCAA AGGATATTAA AGGAATGGAA 1620

GCTAAACAGA CAAAAGTGTT GAAAAGGGAT TCAAAGAAAA CAGATTCATC TAAAATACCA 1680

ACTTTACTTA ATATGGATCA AAATCAAGAA AAACAGGAGG GTGGAGATGG CCATTGTGAG 1740

GGGAAGAATT TGAAGAGGAA CAGATTTTTT TTCTGG 1776

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKETGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+ai+++h nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHGNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifs++++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSTSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ++l++++kkypkln +l+d++++cl++dpaer+s+++ll+heyf

Q: 243   QHLKNARKKYPKLNGLLADIVHACLQIDPAERISSTDLLNHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KETGQIVAIK IFYEKPEKSV NKIATREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI DYLHGNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLTPH LQNIFSTSPI FAGVVLPQVQ 240

HLKNARKKYP KLNGLLADIV HACLQIDPAE RISSTDLLNH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013