EKS-OTG-00394

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00394

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	337.6	5.8E-101	1049	1312	264

Status

Unreviewed

Ensembl Protein

ENSOGAP00000015040

UniProt Accession

H0XG56;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000016799	ENSOGAP00000015040	ENSOGAT00000016804

Organism

Otolemur garnettii

Functional Description

Protein Length

1316

Protein Sequence
(FASTA)

MSSMPTPERH AESLLDICHD TNSSPTDTMT VTKNRNIILQ SISSGEESDQ DDDCGHSILV 60

SEERDPSGDR QHWQPRTEGV EIIMTFPNDV SHPQEMSQED LKENNQTAPM HLEWVPAHSV 120

SPSNEIEMVN LRTKTLATQP LLLKKEESSK ELLDMNLGFL TPRPCLEPSI SKSVTREDTP 180

HFLKGQQRKS GEFSTSDMKC SSRRNEFSLS PLALLPIRSG GFTIPQSHKV PKEKATVPSF 240

IHKRSEPVSQ SDQFSSLNKQ EEAPFKALIH QTLRSSDSSI WSRNMCPFRK ANHHRQHLAM 300

KENWKSREIE GHDKIEIFHI EKEQSLMSFK NFKAGNTPTD KQENIDCHGG KMTKAEECSR 360

YLSSRRKESS GTRNCEQDAE FECTIRAKYS EITPSQDEKV RNNKTGSKSA SLHKGEAVGP 420

NDILEEFTLL KSLSNGVFDD PVEKLQECQN GIETNMKVST NEADKQEMNG LVPLIHITLP 480

ANETPKEPAI AKPNLLKGRG TAHDSRSVNI LAHQEHDKHK MNTHRNKLDS KTKASNKTSQ 540

NFMISAESCI KPTRHKTRIK TQSFPALGFV DSRLQQSPKF QRRMPQIEKK PSAYRTQKPK 600

RQSFPCICKN PGRKKSYVPF SVQPTEPRLN YLDLKYSDMF KEINSTANGP GIYEMFGTPV 660

YCHIREAEQH ENKYYREICS ALSGRCVTNK CRSSNSERNS NSRTKCSQKR PHIKPAKSSL 720

GTKQQHKVLI SKEKSCTVVG RNLSDVENLD GISESDWQIK SSGNDFLSFK HEVHPMNVAH 780

TSERSTDQNE FLPVSDLSIV EEVSMEESAD EGDISNHQIL AMSLRDLQEL EELHHQTPFV 840

TSENSWAVPS EKSTQNVLQE EQNTSFGKIK CNQILANDLE FDSVSDKSKT LINFSFQEKQ 900

ESVSSQTHQR WVYSLDHDSL ENTSITDETF GKALNYANSI SQESLDSLKN EELTDELLGC 960

LAAELLALDE KDNNSCQMMV NQTDLENLNL RLSRRGNATK ELGREKTNVK IQRDSDGFRI 1020

CDREEKFLNS NGKKTFSENT LKYEESILWT KGEILGKGAY GTVYCGLTSQ GQLIAVKQVA 1080

LDTSDKLATE KEYRKLQEEV DLLKALKHVN IVAYLGTCLE ENIVSIFMEF VPGGSISSII 1140

NRFGPLPEMV FCKYTEQILQ GIAYLHENCV VHRDIKGNNV MLMPTGIIKL IDFGCAKRLA 1200

WAGLNGTHSD MLKSMHGTPY WMAPEVINES GYGRKSDIWS IGCTVFEMAT GKPPLASMDR 1260

MAAMFYIGAH RGLMPPLPDH FSEDAADFVR VCLTRDQHER PSAFQLLQHS FLKRSH 1316

Nucleotide Sequence
(FASTA)

ATGAGTTCTA TGCCCACACC AGAAAGACAT GCTGAATCGC TGCTTGACAT TTGTCATGAT 60

ACAAACTCTT CTCCAACTGA TACGATGACA GTTACCAAAA ATCGAAACAT AATCTTGCAA 120

AGCATCAGCA GCGGTGAGGA GTCTGACCAA GATGATGACT GCGGTCACTC TATCCTGGTT 180

AGTGAAGAAA GGGACCCCAG CGGTGACAGA CAGCACTGGC AGCCCAGAAC AGAAGGTGTT 240

GAGATCATTA TGACTTTTCC AAATGATGTC AGTCATCCCC AAGAAATGAG CCAAGAAGAT 300

TTAAAAGAAA ACAATCAGAC AGCTCCAATG CATCTAGAAT GGGTACCAGC ACATTCAGTT 360

TCTCCTTCAA ATGAAATTGA GATGGTGAAC CTCAGGACAA AGACTTTAGC CACACAGCCT 420

TTACTTCTGA AGAAAGAGGA AAGTTCCAAG GAGCTCCTTG ACATGAACTT GGGCTTTTTG 480

ACGCCAAGAC CTTGTTTAGA ACCAAGTATC TCCAAGTCTG TAACCAGAGA AGATACTCCT 540

CATTTCCTGA AGGGGCAGCA AAGAAAATCT GGAGAGTTTT CCACTTCAGA CATGAAGTGC 600

AGCAGCCGAA GAAATGAGTT CTCTCTGTCA CCATTGGCAC TGTTGCCTAT ACGATCTGGT 660

GGCTTTACCA TCCCCCAGAG CCACAAGGTT CCAAAAGAGA AGGCAACCGT TCCATCCTTC 720

ATCCATAAGC GCTCAGAGCC TGTCAGTCAA TCTGATCAGT TTAGTTCATT GAACAAGCAG 780

GAGGAAGCAC CATTTAAGGC ACTGATCCAT CAGACTCTCA GGTCTTCTGA TAGCTCCATT 840

TGGTCAAGAA ACATGTGCCC TTTTCGGAAG GCTAACCATC ATAGACAACA CTTGGCAATG 900

AAGGAGAACT GGAAATCCAG GGAAATAGAA GGACATGACA AAATTGAAAT CTTTCACATT 960

GAAAAGGAGC AATCTTTGAT GTCTTTTAAG AATTTTAAGG CTGGCAATAC TCCCACAGAT 1020

AAGCAAGAGA ATATTGACTG CCATGGTGGT AAAATGACAA AAGCAGAAGA GTGCTCTCGA 1080

TATCTCTCAT CAAGAAGGAA AGAGAGTTCA GGAACCAGAA ACTGTGAACA AGATGCAGAA 1140

TTTGAATGTA CCATTCGAGC CAAATATTCA GAGATCACTC CAAGCCAGGA TGAAAAGGTG 1200

AGAAATAATA AAACTGGTTC AAAAAGTGCT TCGTTACATA AAGGTGAAGC AGTTGGACCA 1260

AACGATATTT TAGAAGAGTT TACTCTACTT AAAAGCTTGT CCAATGGAGT CTTTGATGAC 1320

CCAGTGGAAA AGCTCCAAGA ATGTCAGAAT GGGATAGAAA CAAACATGAA AGTATCAACG 1380

AATGAAGCAG ACAAACAAGA AATGAATGGG TTGGTGCCTC TTATCCATAT CACTCTCCCT 1440

GCAAATGAAA CGCCCAAGGA ACCAGCTATA GCCAAACCAA ACCTCCTAAA AGGAAGGGGA 1500

ACTGCACACG ACAGCCGTAG TGTCAACATA CTTGCGCACC AGGAACATGA CAAACATAAG 1560

ATGAATACCC ACAGAAATAA ATTGGATTCA AAGACCAAGG CAAGTAATAA GACATCTCAG 1620

AATTTCATGA TTTCTGCTGA AAGCTGCATT AAACCTACCA GGCATAAAAC CAGAATAAAA 1680

ACTCAAAGTT TTCCTGCTTT GGGGTTTGTT GACTCCAGGC TTCAGCAGTC ACCCAAGTTT 1740

CAAAGAAGAA TGCCACAGAT CGAGAAGAAG CCATCAGCTT ACCGGACTCA GAAACCTAAA 1800

AGGCAATCAT TTCCTTGCAT CTGTAAAAAT CCGGGAAGAA AAAAGTCATA TGTTCCTTTC 1860

TCTGTTCAAC CAACAGAGCC AAGACTAAAT TACCTAGATC TTAAATATAG TGACATGTTT 1920

AAAGAAATCA ATTCAACTGC TAATGGTCCC GGAATCTATG AGATGTTTGG GACCCCTGTT 1980

TATTGTCACA TTCGAGAAGC TGAACAGCAT GAAAACAAGT ATTACCGAGA GATATGCTCA 2040

GCTCTGTCAG GCAGGTGTGT CACCAATAAA TGTCGATCCT CAAACAGTGA GAGGAACAGC 2100

AATAGCAGAA CAAAATGTTC TCAGAAAAGA CCACATATTA AGCCCGCAAA GTCTTCACTT 2160

GGCACAAAAC AACAGCACAA AGTCTTAATT TCTAAAGAAA AGAGCTGCAC GGTGGTAGGC 2220

CGCAACCTAT CTGATGTTGA AAATCTTGAT GGTATTTCAG AATCAGACTG GCAAATAAAA 2280

TCTTCAGGAA ATGACTTTCT ATCTTTCAAA CATGAAGTTC ATCCCATGAA CGTGGCTCAC 2340

ACTTCTGAAC GGTCCACTGA CCAGAACGAA TTCCTTCCTG TTTCAGACTT ATCCATTGTT 2400

GAAGAAGTTT CTATGGAAGA GTCTGCTGAT GAAGGAGACA TTTCTAACCA TCAGATACTT 2460

GCCATGAGCC TCAGAGATCT GCAAGAACTT GAAGAGCTAC ATCACCAAAC TCCATTTGTC 2520

ACTTCAGAAA ACAGCTGGGC AGTACCCAGT GAGAAGAGTA CCCAGAATGT ACTGCAAGAA 2580

GAACAGAATA CATCTTTTGG TAAAATAAAG TGTAATCAAA TTTTAGCTAA TGATCTGGAG 2640

TTTGATAGTG TTTCAGACAA GTCTAAAACG CTTATAAATT TCTCTTTCCA AGAGAAACAA 2700

GAAAGTGTAT CTTCCCAGAC ACATCAACGT TGGGTATATT CTTTGGATCA TGATAGTTTG 2760

GAAAATACAT CAATCACAGA TGAAACATTC GGAAAAGCTT TAAATTATGC AAATTCAATT 2820

TCCCAAGAAA GCCTGGACTC CTTAAAGAAT GAAGAATTGA CAGATGAACT ATTAGGTTGT 2880

TTAGCTGCAG AATTATTGGC TCTTGATGAG AAAGATAATA ACTCTTGCCA AATGATGGTG 2940

AATCAAACAG ATCTTGAAAA CCTAAATCTT CGCCTCAGTA GGAGAGGAAA TGCCACAAAA 3000

GAATTGGGGA GAGAGAAAAC AAATGTCAAA ATACAGAGAG ACAGTGATGG GTTTAGGATA 3060

TGTGACAGGG AGGAGAAATT TCTCAACTCA AATGGAAAGA AGACATTTTC TGAAAATACT 3120

TTAAAATATG AAGAGTCTAT CCTGTGGACC AAGGGTGAGA TCCTTGGGAA GGGAGCCTAC 3180

GGCACAGTAT ACTGTGGTCT CACTAGCCAA GGGCAGCTAA TAGCTGTAAA ACAGGTAGCT 3240

TTGGATACCT CTGATAAATT AGCTACTGAA AAAGAATACC GGAAACTACA GGAAGAAGTA 3300

GATTTACTCA AAGCACTGAA ACACGTCAAC ATTGTGGCCT ATTTGGGGAC ATGCTTGGAA 3360

GAGAACATTG TGAGCATTTT CATGGAGTTT GTTCCTGGTG GCTCAATCTC TAGTATTATA 3420

AACCGTTTTG GGCCATTGCC TGAGATGGTG TTCTGTAAAT ATACAGAACA AATTCTGCAA 3480

GGTATTGCTT ATCTCCATGA GAACTGTGTG GTGCATCGAG ATATCAAAGG AAATAATGTT 3540

ATGCTCATGC CAACGGGAAT AATAAAGCTG ATTGATTTTG GCTGTGCCAA GCGTTTGGCC 3600

TGGGCAGGAT TAAATGGTAC CCATAGTGAC ATGCTTAAGT CCATGCATGG GACTCCATAT 3660

TGGATGGCTC CCGAAGTCAT CAATGAATCT GGCTATGGAA GGAAATCAGA TATTTGGAGC 3720

ATTGGCTGCA CTGTGTTTGA GATGGCCACA GGCAAACCTC CACTGGCTTC CATGGACAGG 3780

ATGGCAGCCA TGTTTTACAT CGGAGCACAC CGAGGGCTGA TGCCTCCTTT ACCAGACCAC 3840

TTCTCTGAAG ACGCAGCAGA CTTCGTACGT GTGTGTCTAA CCAGGGATCA GCATGAGCGA 3900

CCTTCTGCTT TCCAGCTTCT GCAGCACTCC TTCTTGAAGA GAAGTCACTG A 3951

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++g+l+avK+v++++ +k +++ke+++l+eE++llk+lk

Q: 1049  WTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTsDKLATEKEYRKLQEEVDLLKALK  1107

         89*****************8.89***********8614556778****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv y+G++ ee+ ++if+E+v+gGs+ss+++++g+l e+v++kyt+qil+g+ayLHe

Q: 1108  HVNIVAYLGTCLEENIVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTEQILQGIAYLHE  1167

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 1168  NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHsdmLKSMHGTPYWMAPEVI  1227

         **********************************999988877899**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++p+++se+

Q: 1228  NES--GYGRKSDIWSIGCTVFEMATGKPPLASM-DRMAAMFYIGAHRgLMPPLPDHFSED  1284

         988..****************************.9**********9979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LL+h+fl

Q: 1285  AADFVRVCLTRDQHERPSAFQLLQHSFL  1312

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGQLIAVKQ VALDTSDKLA TEKEYRKLQE EVDLLKALKH 60

VNIVAYLGTC LEENIVSIFM EFVPGGSISS IINRFGPLPE MVFCKYTEQI LQGIAYLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGLNGTH SDMLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSIGCTVFEM ATGKPPLASM DRMAAMFYIG AHRGLMPPLP DHFSEDAADF 240

VRVCLTRDQH ERPSAFQLLQ HSFL 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013