EKS-OTG-00270

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00270

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	366.8	5.9E-110	14	266	253

Status

Unreviewed

Ensembl Protein

ENSOGAP00000018500

UniProt Accession

H0XQV8;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK5

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000027767	ENSOGAP00000018500	ENSOGAT00000024090

Organism

Otolemur garnettii

Functional Description

Protein Length

607

Protein Sequence
(FASTA)

VAAFLRDPSS GRVYRRGKLI GKGAFSHCYK LTDMSTSAVF ALKVVPRRGA GHLCPGGKVE 60

REITLHSCLR HRNIVAFHGH FADRDHVYMV LEYCSRQSLA HVLKARHTLT EPEVRYYLRG 120

LVSGLRYLHQ RHIVHRDLKP SNFFLNKNME VKIGDLGLAA RVGPGGHCHR VLCGTPNFQA 180

PEVISRNGHS CQSDIWALGC IMYMVLTGTP PFMAAPLSEM YQNIRDGHYP EPAHLSPNAR 240

HLIARLLAPN PGERPSLDHL LEDDFFTQGF TPDRLPPHSC HSPPIFTIPL PLGRLFQKAG 300

QLLLSQCRPP CEYITHYPCP HPQRYISRGK QFLCVLSLPR QRAGHRGVLE ERPPLTSAAP 360

CSGLPVQEVS QPLGYGVRIQ NLAANESVST EPEGSQKLEV EVAIRNLQLC LDAGPSAIRN 420

PPGEQQPVIW ALKWVDYSSK YGFGYQLSDG SSGVLLRDGT HMALRSPGGQ VCYMPDRGKL 480

ETFTLRDVPR LLGTKLAVLR LFACHMQQQL RKEGAPPMPT LPARPSLCLL RFLASKQALL 540

LLFNNGTVQV SLTGVQAHLV LSGEGEELLL THWEQGHPGT SYSLGILRSH GCTLATRQLL 600

HHALCML 607

Nucleotide Sequence
(FASTA)

GTGGCCGCCT TCCTGCGCGA CCCGAGCTCG GGACGCGTCT ATAGACGCGG AAAGCTGATC 60

GGCAAGGGTG CTTTTAGCCA CTGCTACAAG CTGACAGACA TGTCCACAAG TGCTGTGTTT 120

GCCCTCAAGG TGGTTCCTCG ACGTGGGGCT GGGCATCTGT GCCCAGGGGG GAAGGTGGAA 180

CGTGAGATCA CCTTGCATAG CTGCCTGCGA CACCGCAATA TTGTGGCCTT CCACGGACAC 240

TTTGCTGACC GTGACCACGT GTACATGGTG TTGGAGTACT GCAGCCGCCA GTCTTTGGCC 300

CACGTGCTGA AGGCACGGCA CACTCTGACG GAGCCTGAGG TGCGCTATTA CCTGCGAGGC 360

CTGGTCAGTG GCCTTCGCTA CCTGCACCAG CGGCACATTG TGCACCGGGA CCTGAAACCA 420

AGTAATTTCT TTCTTAACAA GAACATGGAG GTGAAGATTG GAGACCTGGG GTTGGCTGCC 480

AGGGTGGGGC CAGGGGGCCA CTGCCACAGA GTGCTCTGCG GGACCCCAAA CTTCCAGGCC 540

CCAGAAGTCA TCTCCAGAAA TGGGCACTCC TGCCAGTCAG ACATCTGGGC TCTGGGCTGC 600

ATCATGTACA TGGTACTGAC TGGCACCCCA CCCTTCATGG CGGCACCTCT GTCTGAGATG 660

TACCAGAACA TCCGCGATGG CCACTACCCC GAGCCTGCCC ACCTGTCACC CAATGCACGC 720

CACCTCATTG CCCGCCTTCT AGCACCCAAC CCAGGCGAAC GGCCCAGCCT GGACCACCTG 780

CTGGAAGATG ACTTCTTCAC ACAGGGTTTC ACTCCAGACC GGCTACCACC CCATTCGTGC 840

CATAGCCCAC CCATCTTCAC CATCCCCCTG CCTCTGGGCA GGCTCTTCCA GAAGGCAGGT 900

CAGCTGCTGC TGTCCCAGTG CCGGCCACCT TGTGAGTACA TCACCCACTA CCCCTGCCCA 960

CATCCCCAAC GCTACATCTC AAGAGGAAAA CAGTTCCTCT GTGTGCTGAG TTTGCCAAGG 1020

CAGAGAGCAG GTCACAGAGG GGTCTTGGAG GAAAGGCCGC CCCTCACCTC TGCTGCTCCC 1080

TGCTCAGGTC TCCCTGTCCA AGAAGTAAGT CAACCATTGG GCTATGGAGT GAGGATCCAG 1140

AACTTAGCGG CAAATGAATC TGTTTCCACA GAGCCAGAGG GGAGCCAGAA GTTGGAGGTG 1200

GAGGTGGCCA TCAGAAACCT GCAGCTCTGC CTGGATGCTG GCCCCTCAGC CATACGGAAC 1260

CCCCCAGGAG AGCAGCAGCC AGTCATCTGG GCCCTCAAGT GGGTGGATTA TTCCAGCAAG 1320

TATGGCTTTG GCTACCAGCT GTCAGATGGG AGCAGCGGTG TTCTGCTTCG GGATGGCACC 1380

CACATGGCCC TGCGCTCCCC AGGAGGCCAA GTCTGCTACA TGCCCGACCG CGGGAAACTG 1440

GAGACCTTCA CCCTGAGGGA TGTGCCGAGG CTGCTGGGGA CCAAGCTGGC CGTGCTGCGG 1500

CTCTTCGCCT GCCACATGCA GCAGCAGCTG AGAAAGGAGG GAGCCCCGCC CATGCCCACA 1560

CTGCCAGCCA GGCCCAGCCT CTGCCTACTG CGCTTCTTGG CATCCAAACA AGCCCTGCTG 1620

CTGCTCTTCA ACAATGGGAC AGTGCAGGTC AGCTTGACTG GAGTCCAGGC CCACCTGGTA 1680

CTGAGTGGTG AGGGTGAGGA GTTGTTGCTC ACCCACTGGG AGCAGGGCCA CCCTGGCACC 1740

TCCTACTCCC TGGGCATCCT GCGGAGCCAC GGCTGCACCT TGGCCACCAG ACAGCTCCTT 1800

CACCATGCTC TCTGTATGCT G 1821

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y+rgkl+GkG+f++cy+l+d++t++vfa+kvvp+    +     kve+ei++h+ l+h+n

Q: 14    YRRGKLIGKGAFSHCYKLTDMSTSAVFALKVVPRRGAGHLCPGGKVEREITLHSCLRHRN  73

         99**********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         iv+++ +f+d+++vy+vle+csr+sla++lk+r++ltepevryylr +vsgl+ylh+++i

Q: 74    IVAFHGHFADRDHVYMVLEYCSRQSLAHVLKARHTLTEPEVRYYLRGLVSGLRYLHQRHI  133

         ************************************************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         +hrdlk +n+fln+++evkigd+Gla+r+ + ++++++lcGtPn++aPev+s++ghs+++

Q: 134   VHRDLKPSNFFLNKNMEVKIGDLGLAARVGPGGHCHRVLCGTPNFQAPEVISRNGHSCQS  193

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         diW+lGci+y++l+G+PPf ++ l+e+y++i++ +y  P++ls++a++lia+ll+++P e

Q: 194   DIWALGCIMYMVLTGTPPFMAAPLSEMYQNIRDGHYPEPAHLSPNARHLIARLLAPNPGE  253

         ************************************************************

S: 241   rpsleevlkdefl  253

         rpsl+++l+d+f+

Q: 254   RPSLDHLLEDDFF  266

         ************8

Domain Sequence
(FASTA)

YRRGKLIGKG AFSHCYKLTD MSTSAVFALK VVPRRGAGHL CPGGKVEREI TLHSCLRHRN 60

IVAFHGHFAD RDHVYMVLEY CSRQSLAHVL KARHTLTEPE VRYYLRGLVS GLRYLHQRHI 120

VHRDLKPSNF FLNKNMEVKI GDLGLAARVG PGGHCHRVLC GTPNFQAPEV ISRNGHSCQS 180

DIWALGCIMY MVLTGTPPFM AAPLSEMYQN IRDGHYPEPA HLSPNARHLI ARLLAPNPGE 240

RPSLDHLLED DFF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013