EKS-OTG-00206

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00206

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	452.9	4.1E-136	4	285	282

Status

Unreviewed

Ensembl Protein

ENSOGAP00000015535

UniProt Accession

H0XHE5;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000028062	ENSOGAP00000015535	ENSOGAT00000024415

Organism

Otolemur garnettii

Functional Description

Protein Length

419

Protein Sequence
(FASTA)

FLDYKTIGKI GEGTFSEVMK MQNLRDGKYY ACKQMKQHFE SIEQVNNLRE IQALRRLHPH 60

PNILTLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRHPL SEKKIMYYMY QLCKSLDHMH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT 180

YKMDLWSAGC VFYEIASLRP LFPGANELDQ ISKIHDVIGT PAQKTLIKFK QSRAMSFDFP 240

FKKGSGIPLL TTNLSQQCLS LLHAMVAYDP DERITAHQAL QHPYFKEQRA IEKQALASHR 300

KACFPEHPMA LEPLSNNWQM SKEGRKQKQS LKQEEDHPKR QEPAYIMELP KLKLSGMSKL 360

SSYSSPTLQS VFGSGINGKV PVLRPLKCVG ANKKTDPQKD MKPALKQYRL PTIERKGGG 419

Nucleotide Sequence
(FASTA)

TTTTTAGACT ACAAAACAAT TGGCAAAATA GGAGAGGGAA CATTTTCTGA AGTTATGAAG 60

ATGCAGAACC TGAGAGATGG AAAGTACTAT GCTTGTAAAC AAATGAAACA GCACTTTGAA 120

AGTATTGAGC AAGTGAACAA TCTACGAGAG ATACAAGCAC TGAGGCGCCT GCACCCACAC 180

CCAAACATTC TTACGCTGCA TGAAGTGGTT TTTGACAGAA AATCTGGTTC TCTTGCACTA 240

ATATGTGAAC TTATGGATAT GAATATCTAT GAGCTAATAC GAGGGAGAAG ACATCCATTA 300

TCAGAAAAAA AAATTATGTA CTATATGTAC CAGTTATGTA AATCCCTTGA TCATATGCAC 360

AGAAATGGAA TATTTCACAG AGATGTAAAA CCAGAAAATA TACTAATAAA GCAGGATGTT 420

CTAAAATTAG GGGACTTTGG GTCCTGCCGG AGTGTGTATT CCAAGCAGCC ATATACTGAA 480

TACATCTCTA CGCGCTGGTA CAGAGCCCCA GAGTGTCTCC TCACTGATGG GTTCTACACA 540

TACAAGATGG ACCTGTGGAG CGCTGGCTGT GTGTTCTACG AGATTGCCAG CCTGCGACCC 600

CTCTTCCCTG GTGCCAATGA ACTGGACCAA ATCTCAAAAA TCCATGATGT CATCGGCACA 660

CCTGCTCAGA AGACCCTCAT CAAGTTCAAA CAGTCGAGAG CTATGAGTTT TGATTTTCCT 720

TTTAAAAAGG GATCAGGAAT ACCTCTACTG ACAACCAATT TGTCCCAGCA ATGCCTCTCC 780

CTCCTGCATG CAATGGTGGC CTATGATCCC GATGAGAGAA TCACTGCCCA TCAGGCCCTG 840

CAGCATCCCT ACTTCAAAGA ACAGAGGGCA ATCGAGAAGC AGGCTCTGGC CAGCCACAGA 900

AAAGCTTGCT TTCCAGAGCA CCCTATGGCA CTGGAACCAC TCAGTAACAA CTGGCAAATG 960

TCAAAGGAGG GCAGAAAACA GAAACAGTCC CTAAAGCAAG AGGAGGACCA TCCCAAGAGA 1020

CAAGAACCGG CCTACATAAT GGAACTGCCC AAACTAAAGC TTTCAGGAAT GTCCAAACTG 1080

TCATCTTACT CCAGCCCCAC ACTGCAGTCA GTGTTTGGAT CTGGAATAAA TGGAAAAGTC 1140

CCAGTGTTGA GGCCCTTGAA GTGTGTTGGT GCAAACAAGA AGACAGATCC GCAGAAGGAC 1200

ATGAAACCTG CCCTGAAACA GTATCGCTTG CCCACCATAG AGAGGAAAGG TGGAGGG 1257

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+ev+++++l++g+++a+k+mk++fes+e+v+nlre+++l++l +h+ni

Q: 4     YKTIGKIGEGTFSEVMKMQNLRDGKYYACKQMKQHFESIEQVNNLREIQALRRLHPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++sl+l++elm++n+y+li++rr+ lse+k++ ++yq++k+l+++h++g

Q: 64    LTLHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMYYMYQLCKSLDHMHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+v+sk+Pyt+y+strwyraPe+ll++g+y+++

Q: 124   IFHRDVKPENILIK-QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlw++Gcv++e+a+lrplfPGa+e+dqi+ki++v+GtP++k++ + +k+++a++++fp+

Q: 183   MDLWSAGCVFYEIASLRPLFPGANELDQISKIHDVIGTPAQKTLIK-FKQSRAMSFDFPF  241

         *********************************************9.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++ l++n+s+++l+ll++++aydPder+ta+qal++pyf

Q: 242   KKGSGIPLLTTNLSQQCLSLLHAMVAYDPDERITAHQALQHPYF  285

         *******************************************9

Domain Sequence
(FASTA)

YKTIGKIGEG TFSEVMKMQN LRDGKYYACK QMKQHFESIE QVNNLREIQA LRRLHPHPNI 60

LTLHEVVFDR KSGSLALICE LMDMNIYELI RGRRHPLSEK KIMYYMYQLC KSLDHMHRNG 120

IFHRDVKPEN ILIKQDVLKL GDFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGFYTYKM 180

DLWSAGCVFY EIASLRPLFP GANELDQISK IHDVIGTPAQ KTLIKFKQSR AMSFDFPFKK 240

GSGIPLLTTN LSQQCLSLLH AMVAYDPDER ITAHQALQHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013