EKS-OTG-00292

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00292

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	326.6	1.3E-97	202	503	302

Status

Unreviewed

Ensembl Protein

ENSOGAP00000016883

UniProt Accession

H0XL93;

Protein Name

Protein Synonyms/Alias

Gene Name

AMHR2

Gene Synonyms/Alias

AMHR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000028440	ENSOGAP00000016883	ENSOGAT00000029556

Organism

Otolemur garnettii

Functional Description

Protein Length

560

Protein Sequence
(FASTA)

MLGSLGLWAL RPTAVQAPPN RRTCVFFEAP GVRGSTKTLG ELLGTGPGPP RVIRCLYSHC 60

CFGIWNLTQD QAQVEMQGCR DSDEPGCEAL HCEPTPRAHP SPGSTLFTCS CGTDFCNANY 120

SHLPPPGSPG TPGAQGPQAS PGESIWMALV LLGLFLLLLL LLGSIILVLL QRKACRVQGG 180

PEPEPDSGRD WSEELPELPE LCFSQVIQEG GHTVVWAGRL RGELVAIKAF PARAVAQFRA 240

ERALYELPGL QHDHIVRFIT ASRGGPSPLL SGPLLVLELH PKGSLCHYLT QHTNDWGSSL 300

RMALSLAQGL AFLHEERWQD GQYKPGIAHR DLSSQNVLIR EDGSCAIGDL GLALVLPGLT 360

QPSAWAPTQL QGPAAIMEAG TQRYMAPELL DKTLDLQDWG TALRRADIYS LALLLWEILS 420

RCPDLRPDSR PPPFQLAYEA ELGSTPTTCE LWTLAVEERR RPYIPSTWCC FVTDPGGLRE 480

LLEDCWDADP EARLTAECVQ QRLAALACPP EVPSFPESSP HSCPPLCPED CTLPPSPAIS 540

PMGFRKPKNK TVQQGSCCRN 560

Nucleotide Sequence
(FASTA)

ATGCTGGGGT CTCTGGGACT TTGGGCATTA CGTCCCACAG CTGTGCAAGC ACCTCCAAAC 60

AGGCGGACCT GTGTGTTCTT TGAGGCCCCC GGAGTGCGGG GAAGCACAAA GACACTGGGA 120

GAACTGCTAG GTACAGGACC AGGGCCCCCC AGGGTTATCC GCTGCCTCTA CAGCCACTGC 180

TGCTTTGGGA TCTGGAACCT GACCCAAGAC CAGGCACAGG TGGAGATGCA AGGATGCCGA 240

GACAGTGATG AGCCAGGCTG TGAGGCCCTC CATTGTGAGC CAACCCCCCG AGCCCACCCC 300

AGCCCTGGCT CTACTCTCTT CACTTGCTCC TGTGGCACCG ACTTCTGTAA TGCCAATTAT 360

AGCCACCTGC CTCCTCCAGG GAGCCCTGGG ACTCCTGGTG CCCAGGGTCC CCAGGCCTCC 420

CCAGGTGAGT CCATCTGGAT GGCACTGGTG CTGCTGGGAC TGTTCCTCCT CCTGTTGCTG 480

TTGCTAGGCA GCATCATCTT GGTTCTACTA CAGCGAAAGG CCTGCAGAGT ACAAGGTGGG 540

CCAGAGCCAG AGCCAGACTC AGGCAGAGAC TGGAGTGAGG AGCTACCTGA GCTGCCCGAG 600

CTATGTTTCT CTCAGGTTAT CCAAGAAGGA GGTCACACAG TGGTATGGGC CGGGCGGCTG 660

CGAGGTGAGC TGGTAGCCAT CAAGGCCTTC CCTGCAAGGG CTGTGGCCCA GTTTCGAGCT 720

GAGAGAGCAT TGTACGAGCT GCCAGGCCTA CAGCACGACC ACATTGTCCG CTTTATCACT 780

GCCAGCCGTG GGGGCCCTAG CCCTTTGCTT TCAGGGCCCC TGCTGGTACT GGAACTACAC 840

CCCAAGGGCT CCCTATGCCA CTACTTGACC CAGCACACAA ATGACTGGGG GAGTTCCCTG 900

CGGATGGCAC TGTCTCTGGC CCAGGGTCTG GCATTTCTCC ATGAGGAGCG CTGGCAGGAT 960

GGTCAATATA AACCGGGTAT TGCCCACCGA GATCTGAGCA GCCAGAATGT GCTCATTAGG 1020

GAAGATGGGT CATGTGCAAT TGGAGACTTG GGTCTTGCCT TGGTGCTCCC TGGCCTCACT 1080

CAGCCCTCTG CCTGGGCCCC TACTCAACTG CAAGGTCCAG CTGCCATCAT GGAGGCTGGC 1140

ACCCAGAGGT ACATGGCACC AGAGCTCTTG GACAAGACTC TGGACCTACA GGACTGGGGC 1200

ACAGCCCTCC GGCGAGCTGA TATTTACTCT CTGGCTCTCC TCCTATGGGA GATCCTGAGC 1260

CGCTGTCCTG ATTTGAGGCC TGACAGCAGA CCACCACCCT TCCAACTGGC CTATGAGGCA 1320

GAACTTGGCA GTACCCCCAC CACCTGTGAG CTATGGACCT TGGCAGTGGA GGAGAGGAGG 1380

CGTCCCTACA TCCCATCTAC CTGGTGTTGC TTTGTCACAG ACCCTGGTGG GCTGAGAGAA 1440

CTCCTAGAGG ACTGCTGGGA TGCAGACCCA GAAGCACGGT TGACAGCTGA GTGTGTACAG 1500

CAGCGCCTGG CTGCCCTGGC CTGCCCTCCG GAGGTCCCCT CCTTCCCAGA GAGCTCTCCA 1560

CACAGCTGCC CACCTCTCTG CCCAGAAGAC TGTACTTTAC CTCCTTCTCC TGCCATCTCG 1620

CCCATGGGCT TTAGAAAACC AAAAAATAAA ACGGTTCAGC AAGGCTCTTG CTGCAGGAAT 1680

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++++i++G ++ Vw+++lrge vA+K+f+++  a++++E+++y+++ l+h++i++fi+a

Q: 202   CFSQVIQEGGHTVVWAGRLRGELVAIKAFPARAVAQFRAERALYELPGLQHDHIVRFITA  261

         5789********************************************************

S: 62    dk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

          +   + +l+  llv+e+h+kgsL++yL+++t d+ ++lr+alsla+Gla+LHee ++++

Q: 262   SRgGPSPLLSGPLLVLELHPKGSLCHYLTQHTNDWGSSLRMALSLAQGLAFLHEE-RWQD  320

         **9999*************************************************.8999

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee........ldlaansqvG  172

         g++Kp iaHRDl+s+N+l+++d++c+i+DlGLal l   ++         +  aa++++G

Q: 321   GQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPsawaptqlQGPAAIMEAG  380

         **********************************77666665588898888899******

S: 173   tkRYmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfee  229

         t+RYmaPE+l+++l+l+d+  a++raD+Ysl+L+lWE++sRc +  +d++ ++++l++e+

Q: 381   TQRYMAPELLDKTLDLQDWGtALRRADIYSLALLLWEILSRCPDlrPDSRPPPFQLAYEA  440

         *******************99***********************999*************

S: 230   vvgsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvk  288

         ++gs+P++ e++++ ve++ rP ip++w +   +   l++lle+cWdadpeaRlta++v+

Q: 441   ELGSTPTTCELWTLAVEERRRPYIPSTWCCFVtDPGGLRELLEDCWDADPEARLTAECVQ  500

         ****************************99765899************************

S: 289   krl  291

+rl

Q: 501   QRL  503

Domain Sequence
(FASTA)

CFSQVIQEGG HTVVWAGRLR GELVAIKAFP ARAVAQFRAE RALYELPGLQ HDHIVRFITA 60

SRGGPSPLLS GPLLVLELHP KGSLCHYLTQ HTNDWGSSLR MALSLAQGLA FLHEERWQDG 120

QYKPGIAHRD LSSQNVLIRE DGSCAIGDLG LALVLPGLTQ PSAWAPTQLQ GPAAIMEAGT 180

QRYMAPELLD KTLDLQDWGT ALRRADIYSL ALLLWEILSR CPDLRPDSRP PPFQLAYEAE 240

LGSTPTTCEL WTLAVEERRR PYIPSTWCCF VTDPGGLREL LEDCWDADPE ARLTAECVQQ 300

RL 302

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR015771	; Anti-muellerian_hrmn_rcpt_II.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013