EKS-OTG-00156

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00156

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	521.9	4.1E-157	90	383	294

Status

Unreviewed

Ensembl Protein

ENSOGAP00000018107

UniProt Accession

H0XPR6;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000028901	ENSOGAP00000018107	ENSOGAT00000030973

Organism

Otolemur garnettii

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

MAMTAGTTTT FPMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE VAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLTEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILR 360

FCIDSENRIG NSGVEEIKSH PFFEGVDWGH IRERPAAIPI EIKSIDDTSN FDDFPESDIL 420

QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT QRGSIPTYMK AGKL 464

Nucleotide Sequence
(FASTA)

ATGGCAATGA CGGCAGGGAC TACAACAACC TTTCCTATGA GCAACCATAC CCGAGAAAGA 60

GTGACGGTAG CCAAGCTCAC ACTGGAGAAT TTTTACAGCA ACCTAATTTT ACAACATGAA 120

GAGAGAGAGA CAAGGCAGAA GAAATTAGAA GTGGCCATGG AAGAGGAAGG ATTGGCAGAT 180

GAAGAGAAAA AGTTACGCCG ATCACAGCAT GCTCGCAAAG AAACAGAATT CCTACGGCTC 240

AAGAGGACCA GACTTGGCTT AGATGACTTT GAGTCTTTGA AAGTTATAGG AAGAGGAGCA 300

TTTGGAGAGG TGCGGCTGGT CCAAAAGAAA GATACAGGCC ATATCTATGC AATGAAGATA 360

CTGAGAAAGG CTGATATGCT TGAAAAGGAG CAGGTGGCCC ATATCCGAGC AGAAAGAGAT 420

ATTTTGGTAG AAGCAGATGG TGCCTGGGTA GTGAAGATGT TTTACAGTTT TCAAGATAAG 480

AGGAACCTTT ATCTAATCAT GGAATTTCTC CCTGGAGGTG ACATGATGAC ATTACTAATG 540

AAGAAAGACA CCTTGACAGA AGAGGAAACA CAGTTCTACA TTTCAGAGAC TGTTCTGGCA 600

ATAGATGCAA TCCACCAGTT GGGTTTTATC CATCGGGATA TTAAACCAGA CAACCTTTTA 660

TTGGATGCCA AGGGTCATGT AAAATTATCT GATTTTGGTT TATGCACGGG ATTAAAGAAA 720

GCTCACAGGA CTGAATTCTA TAGAAATCTC ACACACAACC CACCAAGTGA CTTCTCATTT 780

CAGAACATGA ACTCAAAGAG GAAAGCAGAA ACTTGGAAGA AGAACAGGAG ACAACTGGCC 840

TATTCCACAG TTGGGACGCC AGATTATATT GCTCCTGAAG TGTTCATGCA GACTGGTTAC 900

AACAAACTGT GTGACTGGTG GTCTTTGGGA GTGATTATGT ACGAAATGCT AATAGGATAT 960

CCACCTTTCT GCTCTGAAAC GCCTCAAGAA ACATACAGAA AAGTGATGAA CTGGAAAGAG 1020

ACGCTGGTGT TTCCTCCAGA GGTACCTATC TCTGAGAAAG CCAAGGACTT AATTCTCAGA 1080

TTTTGTATTG ATTCTGAAAA CAGAATTGGA AATAGTGGAG TAGAAGAAAT AAAAAGTCAT 1140

CCCTTTTTTG AAGGTGTAGA CTGGGGGCAC ATAAGGGAAA GACCAGCAGC AATTCCTATA 1200

GAAATTAAGA GCATTGATGA CACTTCAAAT TTTGATGACT TCCCTGAATC TGATATTTTA 1260

CAACCAGTGC CAAATACCAC AGAACCAGAC TACAAATCCA AAGACTGGGT TTTTCTCAAT 1320

TATACCTATA AAAGATTTGA AGGGTTGACT CAACGTGGCT CTATCCCCAC CTACATGAAA 1380

GCTGGGAAAC TATGA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++Gv+eik+hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKSHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCIDSENRI GNSGVEEIKS HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013