EPS-OTG-00029

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00029

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.7	1.9E-56	234	487	254

Status

Unreviewed

Ensembl Protein

ENSOGAP00000017817

UniProt Accession

H0XNX6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000030979	ENSOGAP00000017817	ENSOGAT00000030287

Organism

Otolemur garnettii

Functional Description

Protein Length

755

Protein Sequence
(FASTA)

MAGCSPEEKT YRRFLELFLG EFRGPCGGGE PEPEPEPESE PEPEPEPELV AAEAAEASVE 60

DPEEEAATVA ATEEGEQEQD PEPEEGAVEE DAVAAVEGEE EEEVAAVAPG HPAVPPPPQP 120

QLPPLPPLPR PLSERITREE VEGESLDLCL QQLYKYNCPS FLAAALARAT SDEVLQSDLS 180

AHYIPKETDG TEGTVEIETV KLARSVFTKL HEICCSWVKD FPLRRRPQLY YETSIHAIKN 240

MRRKMEDKHV CIPDFNMLFN LEDQEEQAYF AVFDGHGGVD AAIYASVHLH VNLVRQEMFP 300

HDPAEALCRA FRVTDERFVQ KAARESLRCG TTGVVTFIRG NMLHVAWVGD SQVMLVRKGQ 360

AVELMKPHKP DREDEKQRIE ALGGCVVWFG AWRVNGSLSV SRAIGDAEHK PYICGDADSA 420

STVLDGTEDY LILACDGFYD TVNPDEAVKV VSDHLKENNG DSSMVAHKLV ASARDAGSSD 480

NITVIVVFLR DMNKAVNVSE ESDWTENSFQ GGQEDGGDDK ETHGECKRPW PQHQCSAPAD 540

LGYDGRVDSF TDRTSLSPGS QINVLEEPGY LDLTQIEASK PHSAQFLPPV EMFGPGTPKK 600

ANLTNELIME KKSVQSSLPQ WSGAGEFPAS FNLGSTGQQM HRMESLSPVC PGLENEQFKS 660

LGNRVSRLSH LRHHYSKRRH GFRFSPKFYS FLFAQELSHK TGPSLSSLTR SGKRNRMLSS 720

LLRRPNSWKG HSENMRQLSK SHEIPYPDLR WSYKI 755

Nucleotide Sequence
(FASTA)

ATGGCTGGCT GCAGTCCTGA GGAGAAAACT TACCGGCGCT TCCTGGAGCT ATTCCTGGGC 60

GAGTTTCGCG GTCCGTGTGG CGGCGGCGAG CCGGAGCCGG AGCCCGAACC CGAGTCCGAG 120

CCTGAGCCCG AGCCCGAGCC CGAACTGGTA GCAGCTGAGG CGGCCGAGGC TTCGGTTGAG 180

GACCCCGAGG AGGAGGCGGC CACGGTAGCC GCGACAGAGG AGGGGGAGCA GGAGCAAGAC 240

CCGGAGCCCG AGGAGGGGGC GGTGGAGGAG GACGCGGTGG CGGCGGTCGA GGGCGAAGAG 300

GAGGAGGAGG TGGCGGCTGT CGCCCCGGGG CACCCGGCCG TGCCACCGCC GCCGCAGCCC 360

CAGCTGCCCC CGTTGCCCCC GCTGCCGCGG CCGCTGTCGG AGCGCATCAC CCGTGAGGAG 420

GTAGAGGGCG AGAGCCTGGA CCTGTGCCTG CAGCAGCTCT ACAAATATAA TTGCCCTTCC 480

TTTTTGGCCG CTGCTTTAGC CAGAGCCACA TCTGATGAAG TCCTTCAGAG TGATCTTTCT 540

GCACATTATA TACCAAAAGA AACGGATGGC ACAGAAGGGA CTGTGGAGAT TGAGACAGTG 600

AAATTGGCTC GTTCTGTCTT CACCAAACTA CACGAGATTT GCTGCAGCTG GGTGAAAGAC 660

TTCCCTCTCC GCAGGAGACC CCAGCTTTAT TATGAGACAT CAATCCATGC CATCAAAAAC 720

ATGCGCAGGA AAATGGAGGA CAAACATGTC TGCATCCCTG ACTTTAATAT GCTCTTCAAC 780

CTAGAGGACC AGGAAGAACA AGCTTACTTT GCAGTGTTTG ATGGCCACGG GGGAGTGGAT 840

GCTGCCATTT ACGCCTCAGT TCACCTCCAT GTTAACTTAG TTCGCCAGGA GATGTTCCCC 900

CACGATCCTG CTGAGGCGCT GTGCCGGGCT TTCCGGGTCA CTGATGAGCG GTTTGTGCAG 960

AAAGCAGCCA GGGAGAGCTT AAGATGTGGG ACCACCGGAG TCGTAACTTT CATCAGAGGC 1020

AACATGTTGC ACGTGGCCTG GGTGGGTGAT TCCCAGGTTA TGCTTGTGAG AAAGGGCCAA 1080

GCTGTTGAAC TGATGAAGCC CCACAAACCA GACAGAGAGG ATGAAAAGCA GCGAATTGAG 1140

GCCCTTGGAG GTTGTGTAGT CTGGTTTGGT GCCTGGAGGG TGAATGGAAG TCTGTCGGTC 1200

TCCAGAGCTA TTGGAGATGC TGAACATAAG CCGTATATCT GTGGGGATGC CGATTCTGCC 1260

TCCACTGTTT TGGATGGGAC CGAAGACTAC CTCATTCTGG CCTGTGATGG CTTCTATGAT 1320

ACTGTAAACC CTGACGAGGC AGTGAAAGTT GTGTCTGACC ACTTGAAAGA GAATAACGGA 1380

GACAGCAGCA TGGTTGCCCA CAAATTAGTG GCATCAGCTC GCGATGCTGG GTCAAGTGAT 1440

AACATCACTG TTATTGTGGT ATTCCTGAGG GACATGAACA AAGCTGTAAA TGTTAGTGAG 1500

GAATCAGATT GGACAGAGAA CTCTTTTCAA GGAGGGCAAG AAGATGGTGG GGATGATAAG 1560

GAGACTCATG GAGAGTGCAA ACGCCCTTGG CCTCAGCATC AGTGCTCAGC ACCAGCCGAT 1620

CTAGGCTATG ATGGGCGCGT GGATTCATTC ACTGATAGAA CTAGCCTGAG CCCAGGGTCC 1680

CAAATCAACG TGCTGGAAGA ACCAGGCTAC CTAGATCTTA CACAAATAGA AGCAAGCAAA 1740

CCTCACAGTG CCCAGTTTTT GCCACCAGTT GAGATGTTTG GTCCTGGTAC ACCAAAGAAA 1800

GCAAATCTTA CTAATGAGCT AATAATGGAG AAAAAATCAG TTCAATCATC ATTGCCTCAA 1860

TGGAGTGGTG CTGGAGAGTT TCCCGCTTCT TTCAATTTGG GTTCAACAGG GCAGCAGATG 1920

CACAGAATGG AGAGCTTGTC TCCTGTCTGT CCTGGGTTGG AAAATGAACA GTTCAAATCC 1980

CTGGGAAACA GAGTTTCTAG ATTGTCTCAT TTACGCCACC ACTATTCAAA GAGGCGGCAT 2040

GGATTCAGGT TTAGTCCAAA GTTTTATTCA TTTCTCTTTG CTCAAGAGCT TTCCCACAAA 2100

ACAGGCCCTA GCCTATCCTC ACTTACACGA AGTGGGAAGA GAAATAGAAT GTTAAGTTCT 2160

CTGTTACGGA GGCCAAATAG TTGGAAAGGG CACAGTGAAA ACATGAGGCA GCTCAGTAAG 2220

AGTCATGAAA TTCCATACCC AGATCTTCGC TGGAGCTATA AAATATAA 2268

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 234   SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASVHLHVNL  293

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 294   VRQEM----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  347

         99955....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         vGdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 348   VGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  406

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+  +++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 407   AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKeNNGDSSMVA  466

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 467   HKLVASARDAGSSDNITVIVV  487

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASVHLHVNL 60

VRQEMFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>