EKS-OTG-00421

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OTG-00421

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	427.1	2.2E-128	62	320	259

Status

Unreviewed

Ensembl Protein

ENSOGAP00000016725

UniProt Accession

H0XKT5;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17A

Gene Synonyms/Alias

STK17A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000033031	ENSOGAP00000016725	ENSOGAT00000024911

Organism

Otolemur garnettii

Functional Description

Protein Length

412

Protein Sequence
(FASTA)

MIPLEKPGSG DSSPATATGS GPALRGLSTP RRQPSPQARG LQTEIRAAVR TEPFQDGYSL 60

CPGRELGRGK FAVVRKCIKK DSGKEFAAKF MRKRRKGQDC RMEIIHEIAV LELAQDNPWV 120

INLHEVYETP SEMILVLEYA AGGEIFDQCV ADREEAFKEK DVQRLMRQIL EGVHFLHIHN 180

VVHLDLKPQN ILLTSDSPLG DIKIVDFGLS RIMKNSEELR EIMGTPEYVA PEILSYDPIS 240

MATDMWSIGV LTYVMLTGIS PFLGNNKQET FLNISQMNLS YSEEEFDVVS ESAIDFIKTL 300

LVKKPEDRAT AEECLQHPWL TQNSIQDPSL RVKGALEEPN ALQEGDDSVP EINFGKPETE 360

ESIVTEDLIV VTSYTLGQCR QSEKEKMEQK AISKRFKFEE PLLQEIPGEF IY 412

Nucleotide Sequence
(FASTA)

ATGATCCCTT TGGAGAAGCC GGGCAGCGGT GACTCCTCCC CCGCCACCGC CACTGGCTCG 60

GGCCCGGCCC TCCGGGGTCT GAGCACGCCG CGCCGGCAGC CTTCGCCCCA AGCCCGCGGG 120

CTGCAGACTG AGATCCGCGC CGCAGTACGC ACCGAGCCCT TCCAGGACGG CTACAGCCTG 180

TGCCCCGGCC GGGAGCTGGG CAGGGGAAAA TTTGCAGTGG TGAGGAAATG TATAAAGAAA 240

GATTCTGGGA AAGAATTTGC TGCAAAGTTC ATGAGAAAAA GAAGAAAAGG CCAAGATTGT 300

CGGATGGAAA TAATTCATGA GATTGCTGTA CTTGAACTAG CGCAGGACAA TCCTTGGGTC 360

ATTAATTTAC ATGAAGTTTA TGAGACTCCC TCAGAAATGA TTTTAGTTTT GGAATATGCT 420

GCTGGGGGTG AAATCTTTGA CCAGTGTGTT GCAGACAGAG AAGAAGCCTT TAAAGAAAAA 480

GATGTCCAAA GACTCATGCG ACAGATTCTA GAAGGTGTTC ACTTTTTACA CATTCATAAT 540

GTTGTTCATC TTGATTTGAA GCCTCAGAAT ATTCTGCTGA CAAGTGATTC TCCACTGGGT 600

GACATTAAGA TCGTTGACTT TGGCCTTTCA AGAATAATGA AGAACAGTGA AGAGCTCCGA 660

GAGATTATGG GTACTCCTGA ATATGTGGCT CCTGAAATTC TTAGTTATGA TCCTATCAGC 720

ATGGCAACGG ATATGTGGAG CATTGGCGTT TTAACGTATG TCATGCTTAC AGGAATATCA 780

CCCTTCTTAG GCAATAATAA ACAAGAAACA TTTTTGAACA TCTCACAGAT GAATTTAAGT 840

TATTCTGAGG AAGAGTTTGA TGTTGTATCT GAGTCAGCTA TTGACTTCAT CAAGACACTT 900

TTAGTGAAGA AACCTGAAGA TCGAGCCACT GCAGAAGAAT GTCTACAACA TCCCTGGTTG 960

ACACAGAACA GTATTCAAGA TCCTTCTCTC AGGGTGAAAG GGGCTTTAGA AGAACCAAAT 1020

GCCCTTCAAG AAGGTGATGA TTCTGTGCCT GAAATTAATT TTGGCAAACC AGAAACTGAG 1080

GAATCAATTG TAACAGAGGA CTTAATTGTA GTTACTTCGT ATACTTTAGG ACAGTGCAGA 1140

CAGTCTGAAA AAGAGAAAAT GGAGCAAAAG GCCATTTCCA AACGATTTAA ATTTGAGGAA 1200

CCTTTGCTAC AAGAAATTCC AGGAGAATTT ATCTACTGA 1239

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

          g+elg+Gkfavvrkc++k++Gke+aakf++krr    +++++r+ei +e+avl++++++

Q: 62    PGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRR----KGQDCRMEIIHEIAVLELAQDN  117

         689*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vinlhevye+ s++il+le++aGGe+fd  +++++e+++e+++++l++qilegv++lh

Q: 118   PWVINLHEVYETPSEMILVLEYAAGGEIFDqcVADREEAFKEKDVQRLMRQILEGVHFLH  177

         ******************************988999************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

          +++vhldlkP+nill++ + p gdik++dfGlsr +++++el+ei+GtPe+vaPei++y

Q: 178   IHNVVHLDLKPQNILLTSDS-PLGDIKIVDFGLSRIMKNSEELREIMGTPEYVAPEILSY  236

         *******************9.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p+s++tdmwsiGv+ty++l+g+sPflG++kqet+lnis++nl++see f+ vse+a+df

Q: 237   DPISMATDMWSIGVLTYVMLTGISPFLGNNKQETFLNISQMNLSYSEEEFDVVSESAIDF  296

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i++llvk+pe+r+t+eecl+h+wl

Q: 297   IKTLLVKKPEDRATAEECLQHPWL  320

         ***********************7

Domain Sequence
(FASTA)

PGRELGRGKF AVVRKCIKKD SGKEFAAKFM RKRRKGQDCR MEIIHEIAVL ELAQDNPWVI 60

NLHEVYETPS EMILVLEYAA GGEIFDQCVA DREEAFKEKD VQRLMRQILE GVHFLHIHNV 120

VHLDLKPQNI LLTSDSPLGD IKIVDFGLSR IMKNSEELRE IMGTPEYVAP EILSYDPISM 180

ATDMWSIGVL TYVMLTGISP FLGNNKQETF LNISQMNLSY SEEEFDVVSE SAIDFIKTLL 240

VKKPEDRATA EECLQHPWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013