EPS-OTG-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OTG-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	204.0	3.3E-60	64	321	258

Status

Unreviewed

Ensembl Protein

ENSOGAP00000019198

UniProt Accession

H0XSV6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1N

Gene Synonyms/Alias

PPM1N;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOGAG00000033341	ENSOGAP00000019198	ENSOGAT00000028746

Organism

Otolemur garnettii

Functional Description

Protein Length

427

Protein Sequence
(FASTA)

MAALARLLER LLRPTRKEKE GEEEEEEEGE AGRRALARPQ SLLAAPRCAQ QPHGGAAASW 60

GLRFGASAAQ GWRARMEDAH CAWLTLPGLP PGWAFFAVLD GHGGARAARF GARHLPGHVI 120

EALGPTPGEP EGVRWALRRA FLTADERLRS LWPRGEQGGS TAVALLVSPR FLYLAHCGDS 180

RAVLSRAGAV AFSTEDHRPF RPRERERIHD AGGTICRRRI EGSLAVSRAL GDFAYKEAPG 240

RPPEQQLVSA EPEVAALARQ AEDEFMVLAS DGVWDAISGA DLAGLVASRL RLGLAPELLC 300

AQLLDTCLCK GSLDNMTCIL VCFPGAPRPC EEALRRELAL DTALGHRVAE LCASAQEPPS 360

LNSVFMTLAS EDIPDLPPGG GLYCKATIIA EAYSQLFQAS RECWEKGQDE AGKLTGTHSD 420

SVLDLEA 427

Nucleotide Sequence
(FASTA)

ATGGCTGCCC TTGCCCGCTT GCTGGAGCGT CTCCTCCGAC CTACTCGCAA GGAAAAGGAG 60

GGGGAAGAGG AGGAAGAAGA GGAGGGTGAG GCGGGGCGCC GGGCTCTAGC TCGGCCTCAG 120

TCTCTCCTGG CTGCACCGCG ATGCGCCCAG CAGCCACACG GGGGTGCCGC AGCGTCTTGG 180

GGCCTGCGCT TCGGGGCAAG CGCAGCTCAG GGCTGGCGCG CACGCATGGA GGACGCGCAC 240

TGCGCTTGGC TCACTTTACC TGGGTTGCCC CCGGGCTGGG CTTTCTTTGC TGTACTCGAC 300

GGCCACGGCG GGGCGCGAGC TGCTCGCTTT GGTGCGCGCC ACCTGCCTGG CCACGTGATC 360

GAGGCGCTGG GCCCCACACC TGGCGAGCCT GAGGGCGTAC GCTGGGCGCT GCGCCGAGCT 420

TTCTTGACCG CGGACGAGCG CCTGCGTTCT CTCTGGCCCC GCGGCGAACA GGGCGGCTCC 480

ACGGCTGTGG CATTGCTCGT CTCTCCGCGC TTTCTATACC TGGCGCACTG CGGTGACTCT 540

CGTGCGGTGC TGAGCCGCGC CGGCGCTGTG GCCTTCAGCA CCGAGGACCA TCGACCTTTC 600

CGTCCCCGGG AACGCGAGCG CATCCACGAC GCGGGCGGCA CCATCTGCCG CCGGCGCATC 660

GAGGGCTCTC TGGCCGTGTC GCGAGCACTA GGCGACTTTG CTTACAAGGA GGCTCCGGGG 720

AGGCCCCCAG AGCAGCAGCT CGTTTCCGCG GAGCCTGAAG TGGCCGCACT GGCACGCCAG 780

GCTGAGGACG AGTTCATGGT CCTGGCCTCC GACGGAGTGT GGGACGCTAT ATCTGGTGCT 840

GACCTGGCCG GGCTGGTAGC TTCGCGCCTC CGTTTAGGCC TGGCCCCAGA GCTTCTTTGC 900

GCGCAACTGT TGGACACGTG TCTGTGCAAG GGCAGCCTGG ACAACATGAC CTGCATCCTG 960

GTCTGCTTCC CAGGGGCTCC CAGACCTTGT GAGGAGGCCC TCAGGAGAGA GCTGGCGCTG 1020

GACACAGCCT TGGGCCACAG AGTTGCTGAG CTGTGTGCCT CTGCTCAGGA GCCCCCCAGC 1080

CTAAACAGTG TTTTTATGAC TCTGGCCTCA GAAGACATCC CCGATTTACC TCCTGGGGGA 1140

GGGCTGTACT GCAAGGCCAC CATCATCGCT GAAGCTTATT CTCAGCTCTT CCAGGCCTCA 1200

AGAGAGTGCT GGGAGAAAGG GCAAGATGAG GCTGGGAAGC TCACTGGCAC CCATTCGGAC 1260

TCTGTCTTGG ACTTGGAAGC CTGA 1284

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++ +g+r  meda+ +   +   p     +aff+v DGhgg ++a+f + +l  ++

Q: 64    FGASAAQGWRARMEDAHCAWLTLPGLPPG---WAFFAVLDGHGGARAARFGARHLPGHVI  120

         68899************875555555554...****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         e l  + +e + v+ al++aFl+ de+l    +   + ++ Gstav  l+++  ly a++

Q: 121   EALGPTPGEPEGVRWALRRAFLTADERL---RSLWPRGEQGGSTAVALLVSPRFLYLAHC  177

         ****999999999999************...444456999********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSravL+r g +   ++dH+p r++E+eRi +agg++ ++   R+ G+LavsRalGd+

Q: 178   GDSRAVLSRAGAVAFSTEDHRPFRPRERERIHDAGGTICRR---RIEGSLAVSRALGDFA  234

         ************9**************************99...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v++ePev    ++ edef++LasDG+wd +s  ++  lv ++l+ +

Q: 235   YKeapgrppeqQLVSAEPEVAALARQAEDEFMVLASDGVWDAISGADLAGLVASRLRLGL  294

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         a++  + +L++++l +gs dn++ i+v

Q: 295   APELLCAQLLDTCLCKGSLDNMTCILV  321

         **********************99876

Domain Sequence
(FASTA)

FGASAAQGWR ARMEDAHCAW LTLPGLPPGW AFFAVLDGHG GARAARFGAR HLPGHVIEAL 60

GPTPGEPEGV RWALRRAFLT ADERLRSLWP RGEQGGSTAV ALLVSPRFLY LAHCGDSRAV 120

LSRAGAVAFS TEDHRPFRPR ERERIHDAGG TICRRRIEGS LAVSRALGDF AYKEAPGRPP 180

EQQLVSAEPE VAALARQAED EFMVLASDGV WDAISGADLA GLVASRLRLG LAPELLCAQL 240

LDTCLCKGSL DNMTCILV 258

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013