EKS-ORN-00544

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00544

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	533.1	1.8E-160	82	339	258

Status

Unreviewed

Ensembl Protein

ENSONIP00000000573

UniProt Accession

I3IVD4;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000000452	ENSONIP00000000573	ENSONIT00000000572
ENSONIG00000000452	ENSONIP00000000574	ENSONIT00000000573

Organism

Oreochromis niloticus

Functional Description

Protein Length

415

Protein Sequence
(FASTA)

MKDKTTSLTS FMKQRRMGLN DFIQRLATNS YACKHSEVQS ILNLSPPQDP ELMNTNPSPP 60

PSPSQQINLG PSSNPSAKPS DFHFLKVIGK GSFGKVLLAR HRTDDNFYAV KVLQKKAILK 120

KKEEKHIMSE RNVLLKNVKH PFLVGLHYSF QTADKLYFVL DYINGGELFY HLQRERCFLE 180

PRARFYAAEI ASALGYLHSL NIVYRDLKPE NILLDSQGHI ILTDFGLCKE NIEPNGTTST 240

FCGTPEYLAP EVLHKQPYDR TVDWWCLGAV LYEMLYGLPP FYSRNTAEMY DNILNKPLQL 300

KPNISNSARH LLEGLLQKDR TKRLGCSDDF IEIKNHIFFT PINWDDLNAK KITPPFNPNV 360

TGPNDLRHFD PEFTDEPVPS SIGCSPDSAL VTASIKEAAE AFVGFSYAPS MDSYL 415

Nucleotide Sequence
(FASTA)

ATGAAAGACA AAACGACATC TCTGACGTCT TTTATGAAAC AAAGGAGGAT GGGTCTGAAC 60

GACTTCATTC AGAGGCTTGC CACAAACTCC TACGCCTGCA AGCATTCCGA GGTTCAGTCC 120

ATCCTGAACT TGAGTCCTCC TCAGGATCCT GAGCTCATGA ACACAAACCC CTCTCCTCCT 180

CCCAGTCCAT CCCAACAGAT CAACCTCGGC CCATCATCCA ATCCTTCGGC CAAGCCCAGC 240

GACTTCCACT TCCTCAAGGT TATCGGCAAG GGCAGCTTCG GAAAGGTTTT GCTTGCACGC 300

CATCGCACGG ATGACAACTT CTACGCTGTC AAAGTCTTAC AGAAGAAGGC CATTCTCAAG 360

AAGAAGGAGG AAAAACACAT CATGTCAGAG AGGAATGTGC TGTTGAAGAA TGTCAAGCAC 420

CCGTTCTTGG TGGGCCTGCA CTATTCTTTC CAAACAGCGG ACAAACTGTA CTTCGTCTTG 480

GACTACATCA ATGGCGGAGA GTTGTTCTAC CACCTGCAGA GAGAGCGCTG CTTCCTCGAG 540

CCCAGAGCCA GGTTCTATGC AGCAGAGATC GCCAGCGCAC TGGGATACCT GCACTCACTA 600

AACATTGTCT ACAGAGACCT GAAACCAGAG AACATCCTGC TGGACTCCCA GGGACACATC 660

ATTCTCACAG ATTTTGGACT CTGCAAGGAG AACATTGAAC CCAACGGGAC AACATCGACT 720

TTCTGCGGTA CTCCAGAGTA TTTGGCTCCT GAGGTGTTGC ACAAGCAGCC GTATGACAGG 780

ACAGTAGACT GGTGGTGTTT AGGAGCTGTT CTCTATGAGA TGCTGTATGG CCTGCCTCCG 840

TTCTACAGCC GCAACACAGC GGAGATGTAC GACAACATCC TGAACAAGCC ACTGCAGCTG 900

AAACCCAACA TTTCCAACTC GGCTAGACAC CTGCTGGAGG GCCTGCTGCA AAAAGACCGG 960

ACAAAGAGAC TGGGCTGCTC CGACGACTTC ATTGAAATTA AGAACCACAT ATTCTTTACC 1020

CCCATCAACT GGGATGACCT CAATGCAAAG AAGATCACCC CTCCCTTCAA CCCTAATGTG 1080

ACGGGGCCCA ATGACCTGCG GCACTTTGAT CCGGAGTTCA CAGACGAGCC GGTACCCAGC 1140

TCCATCGGTT GCTCCCCAGA CAGTGCACTC GTCACAGCCA GCATCAAAGA GGCGGCCGAG 1200

GCCTTTGTGG GCTTCTCTTA TGCCCCATCT ATGGACTCCT ACCTATAG 1248

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+flkvigkgsfgkvlla++++d++fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 82    FHFLKVIGKGSFGKVLLARHRTDDNFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  141

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqta+klyfvldy+nggelf+hlqrer+fleprarfyaaeiasalgylhsln

Q: 142   FLVGLHYSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN  201

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh++ltdfglcke+ie + ttstfcgtpeylapevl+k+pydrt

Q: 202   IVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRT  261

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysr++aemydnilnkplqlkp+is++a++lle+ll+kdr+

Q: 262   VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNSARHLLEGLLQKDRT  321

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlg  +df+eiknh+ff

Q: 322   KRLGCSDDFIEIKNHIFF  339

         *****************9

Domain Sequence
(FASTA)

FHFLKVIGKG SFGKVLLARH RTDDNFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHYSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHII LTDFGLCKEN IEPNGTTSTF CGTPEYLAPE VLHKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNISNSARHL LEGLLQKDRT 240

KRLGCSDDFI EIKNHIFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013