EKS-ORN-00265

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00265

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	528.0	5.4E-159	4	287	284

Status

Unreviewed

Ensembl Protein

ENSONIP00000000615

UniProt Accession

I3IVH5;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000000483	ENSONIP00000000615	ENSONIT00000000614

Organism

Oreochromis niloticus

Functional Description

Protein Length

354

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNKDTGQIV AIKKFVESED NPIIKKIALR EIRMLKQLKH 60

SNLVNLIEVF RRKRKLHLVF EYCDHTVLNE LDRHPRGVPE HLVKSITWQT LQAVNFCHKQ 120

NCIHRDVKPE NILITKHQVI KLCDFGFARI LTGPCDYYTD YVATRWYRAP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGTP LWPGKSDMDQ LYLIIKTLGD LIPRHQQVFS NNQFFCGVSI 240

PEPQQMESLE QKYPNLSQQT LSLMKGCLRM DPSERLTCEQ LLQHPYFDSL RERNESTSRQ 300

QDRSGNKRTR LPRRHDFCAL QYLPQLTSSG FFPALDNKRY YNNLRKFNYH LPNI 354

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ACGAGAAGAT TGGGAAGATT GGAGAGGGCT CATACGGAGT CGTCTTCAAG 60

TGCAGAAACA AAGACACGGG CCAGATCGTC GCCATCAAGA AGTTTGTCGA GTCAGAGGAT 120

AATCCCATCA TTAAAAAAAT TGCACTGAGG GAGATCAGGA TGCTCAAGCA ACTGAAACAC 180

TCAAACCTGG TGAATCTGAT CGAAGTGTTT CGACGCAAAC GGAAGCTTCA CCTGGTCTTC 240

GAGTACTGCG ATCACACCGT CCTCAACGAG CTGGACCGCC ATCCCAGAGG CGTCCCAGAG 300

CATCTTGTAA AAAGTATAAC CTGGCAGACT CTTCAGGCTG TCAACTTCTG CCACAAACAG 360

AATTGCATCC ATAGAGACGT CAAGCCAGAG AATATTCTCA TCACCAAGCA TCAAGTCATC 420

AAACTCTGCG ACTTTGGGTT CGCCAGGATA CTCACTGGGC CATGTGACTA CTACACAGAC 480

TACGTTGCGA CCCGCTGGTA TCGCGCCCCC GAACTGCTAG TGGGAGACAC TCAGTACGGC 540

CCCCCGGTGG ACGTGTGGGC AATCGGTTGC GTGTTCGCTG AGCTCCTGTC GGGGACGCCT 600

CTGTGGCCCG GGAAGTCGGA CATGGATCAG CTGTACCTGA TCATAAAGAC CCTCGGAGAT 660

CTGATTCCTC GACACCAGCA GGTCTTCAGC AACAACCAGT TCTTCTGTGG AGTATCCATT 720

CCAGAGCCAC AACAGATGGA ATCTTTGGAG CAAAAGTATC CAAACCTCTC ACAGCAAACT 780

CTGAGCCTGA TGAAGGGCTG TCTGCGGATG GACCCGTCTG AGCGGCTGAC CTGTGAGCAG 840

CTCCTCCAGC ATCCGTACTT CGACAGCCTG AGAGAAAGAA ACGAGAGCAC ATCTCGACAG 900

CAGGACCGCT CCGGCAACAA AAGGACACGT TTACCTCGCA GACACGATTT TTGTGCTCTA 960

CAGTATTTGC CACAGTTGAC CAGCAGCGGC TTCTTTCCAG CTCTGGACAA TAAGAGGTAC 1020

TACAACAACC TGCGCAAATT CAACTATCAC CTACCGAACA TCTAA 1065

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrnkdtgqivaikkf+esed++ +kkialrei++lkqlkh nl

Q: 4     YEKIGKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDNPIIKKIALREIRMLKQLKHSNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+kl+lvfey+d+tvl+el+r+p+Gv+e+lvk+i++q+l+a++fchk+n+i

Q: 64    VNLIEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVPEHLVKSITWQTLQAVNFCHKQNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfar+l++p d+ytdyvatrwyrapellvgdt+yG++v

Q: 124   HRDVKPENILITKHQVIKLCDFGFARILTGPCDYYTDYVATRWYRAPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G+pl+pgksd+dqly+i+ktlG+liprhq++fs+n++f Gv++pe+

Q: 184   DVWAIGCVFAELLSGTPLWPGKSDMDQLYLIIKTLGDLIPRHQQVFSNNQFFCGVSIPEP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++esle+kyp+l++ +l+l+k+cl++dp+erl+ce+ll+h+yf

Q: 244   QQMESLEQKYPNLSQQTLSLMKGCLRMDPSERLTCEQLLQHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN KDTGQIVAIK KFVESEDNPI IKKIALREIR MLKQLKHSNL 60

VNLIEVFRRK RKLHLVFEYC DHTVLNELDR HPRGVPEHLV KSITWQTLQA VNFCHKQNCI 120

HRDVKPENIL ITKHQVIKLC DFGFARILTG PCDYYTDYVA TRWYRAPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGTPLWP GKSDMDQLYL IIKTLGDLIP RHQQVFSNNQ FFCGVSIPEP 240

QQMESLEQKY PNLSQQTLSL MKGCLRMDPS ERLTCEQLLQ HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013