EKS-ORN-00318

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00318

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.9	2.1E-101	18	270	253

Status

Unreviewed

Ensembl Protein

ENSONIP00000003507

UniProt Accession

I3J3R7;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000002797	ENSONIP00000003508	ENSONIT00000003509
ENSONIG00000002797	ENSONIP00000003507	ENSONIT00000003508

Organism

Oreochromis niloticus

Functional Description

Protein Length

559

Protein Sequence
(FASTA)

MAERQQQKHE GRVKIGHYIL GDTLGVGTFG KVKIGEHQLT GHKVAVKILN RQKIRSLDVV 60

GKIKREIQNL KLFRHPHIIK LYQVISTPTD FFMVMEYVSG GELFDYICKN GRVEDTEARR 120

LFQQIISAVD YCHRHMVVHR DLKPENVLLD ANKNAKIADF GLSNMMSDGE FLRTSCGSPN 180

YAAPEVISGR LYAGPEVDIW SCGVILYALL CGTLPFDDEH VPTLFKKIRG GVFYIPEYLT 240

RSVASLLMLM LQVDPLKRAT IKDIREHEWF KQDLPGYLFP EDPSYDATVL DEEAVREVCE 300

KFECTESEVV TSLYSGDPQD QLAVAYHLII DNRRIMTQAS EFYLASSPPQ GSFIEEGMPL 360

PPGVKPHPER MPPLLADSPK SRCPLDALNT TRPKPLAVKK AKWHLGIRSQ SRPYDIMAEV 420

YRAMKQLNFD WKAVFLNIYL LRVRRKNPVT GNLVKMSLQL YQVDNRSYLL DFKSIDDDII 480

EAVGFKSGSS TPQRSGSTAG LHRPRLSIDS ATPAIDLPQL SSSLPGSLSG SSHLLTPRQG 540

SHTMDFFEMC ASLITTLAR 559

Nucleotide Sequence
(FASTA)

ATGGCAGAGA GGCAACAACA GAAACACGAA GGCAGGGTAA AGATCGGCCA TTACATCCTC 60

GGCGACACGC TCGGAGTGGG GACATTCGGC AAAGTGAAGA TTGGTGAGCA TCAGTTGACA 120

GGCCATAAAG TGGCTGTGAA GATCCTGAAC AGACAGAAGA TCCGTAGTCT CGATGTTGTG 180

GGGAAGATCA AACGAGAGAT CCAGAATCTT AAGCTGTTCA GACACCCACA CATCATCAAG 240

CTGTACCAGG TCATAAGCAC ACCGACAGAT TTTTTCATGG TCATGGAGTA TGTGTCGGGA 300

GGCGAGCTGT TTGATTACAT CTGCAAGAAT GGACGGGTGG AGGACACTGA AGCACGCCGC 360

CTCTTCCAGC AGATTATCTC AGCTGTAGAC TACTGTCACC GGCACATGGT GGTCCACAGA 420

GACCTCAAAC CTGAGAATGT CCTATTGGAT GCCAATAAGA ATGCAAAGAT AGCAGACTTT 480

GGACTGTCAA ACATGATGTC AGATGGAGAA TTCCTACGAA CTAGCTGTGG CTCACCCAAC 540

TATGCAGCTC CAGAAGTCAT CTCAGGAAGA CTCTACGCAG GCCCAGAAGT TGACATCTGG 600

AGCTGTGGTG TGATTCTGTA TGCCCTGCTG TGTGGCACCC TGCCCTTTGA TGATGAGCAT 660

GTCCCCACAC TGTTTAAGAA GATCAGAGGA GGTGTCTTTT ACATCCCAGA GTACCTGACC 720

CGCTCTGTGG CCTCGTTGCT GATGCTAATG CTGCAGGTGG ATCCTTTGAA GAGAGCCACC 780

ATTAAAGACA TCAGGGAACA CGAATGGTTT AAGCAGGACC TACCAGGCTA CCTTTTCCCA 840

GAGGATCCGT CATATGATGC AACTGTTCTG GATGAAGAGG CTGTCAGGGA AGTGTGCGAG 900

AAGTTTGAAT GCACTGAATC TGAGGTTGTG ACCAGCCTGT ACAGTGGAGA TCCACAGGAT 960

CAGTTAGCCG TAGCCTATCA CCTCATCATA GATAACAGGC GCATCATGAC CCAGGCCAGT 1020

GAATTCTATT TGGCGTCCAG TCCTCCACAG GGCTCCTTTA TAGAGGAGGG AATGCCGTTA 1080

CCCCCTGGAG TTAAACCTCA CCCAGAGAGG ATGCCTCCGC TCTTGGCTGA CAGCCCAAAG 1140

TCTCGTTGTC CTCTGGATGC TCTCAACACC ACTCGGCCTA AACCGCTGGC AGTGAAGAAG 1200

GCTAAGTGGC ACCTGGGTAT CAGGAGTCAG AGCAGACCCT ATGATATCAT GGCTGAGGTG 1260

TACAGAGCTA TGAAGCAACT CAACTTTGAC TGGAAGGCTG TTTTTTTAAA TATTTATTTA 1320

TTGCGAGTGC GAAGGAAGAA TCCAGTGACA GGCAACTTGG TGAAAATGAG CCTGCAGCTC 1380

TATCAAGTGG ACAACAGGTC CTACCTCCTT GACTTCAAGA GCATTGATGA TGACATCATC 1440

GAGGCAGTGG GCTTTAAATC GGGCTCATCC ACTCCTCAGA GGTCAGGTTC CACAGCCGGT 1500

CTCCACAGGC CCAGACTGAG CATTGACTCG GCAACCCCAG CGATTGATCT GCCCCAGCTC 1560

AGCTCCTCTC TCCCGGGATC CCTGTCTGGT AGCTCCCATC TACTCACCCC ACGTCAGGGA 1620

TCACACACCA TGGACTTCTT TGAAATGTGT GCCAGTCTGA TCACTACACT AGCACGCTGA 1680

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk  +h++t++kvavKi++++k+ s + + kikrEi+ lk ++hp+

Q: 18    YILGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIrSLDVVGKIKREIQNLKLFRHPH  77

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++gr++ +ear+lf+q++sav+Y+h++ +

Q: 78    IIKLYQVISTPTDFFMVMEYVSGGELFDYICKNGRVEDTEARRLFQQIISAVDYCHRHMV  137

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 138   VHRDLKPENVLLDANKNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  197

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + ip++l+++++sLl  +L+vdp k

Q: 198   DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLTRSVASLLMLMLQVDPLK  257

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 258   RATIKDIREHEWF  270

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKIGEH QLTGHKVAVK ILNRQKIRSL DVVGKIKREI QNLKLFRHPH 60

IIKLYQVIST PTDFFMVMEY VSGGELFDYI CKNGRVEDTE ARRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDANKNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSCGVILY ALLCGTLPFD DEHVPTLFKK IRGGVFYIPE YLTRSVASLL MLMLQVDPLK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013