EKS-ORN-00269

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00269

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	408.9	1.1E-122	29	300	272

Status

Unreviewed

Ensembl Protein

ENSONIP00000003962

UniProt Accession

I3J522;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL5 (2 of 2)

Gene Synonyms/Alias

CDKL5 (2 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000003161	ENSONIP00000003962	ENSONIT00000003963

Organism

Oreochromis niloticus

Functional Description

Protein Length

999

Protein Sequence
(FASTA)

FMISKIGDVL NMIHVMTILL ELFAGLLILI LKTKMKDTNE IVAIKKFKDS EENEEVKETT 60

LRELKMLRTL KQENIVELKE AFRRRGKLYL VFEYVEKNML ELLEELPNGV PSEKARSYIF 120

QLIKAIHWCH KHDIVHRDIK PENLLISSDD VLKLCDFGFA RNLSEGTDAN YTEYVATRWY 180

RSPELLLGAP YGKAVDMWSV GCILGELSDG QPLFPGESEI DQLFTIQKVL GPLPPEQMKL 240

FYNNPRFHGL RFPTVSHPQT LERRYLGIID AALLDLLKNM LLLNPTERFL TEQSLNHHAF 300

QTLRMVERPG PPTPTPVRSS KRKPHHGDNT TPSRSHGGKS SGSHRSSSRE CSSLPRHEDL 360

HPNNDSFLNG NMSAAINLSP TLHPKNYQPQ IFNHSTACSM DLASSNLPHL LSPGETKSKG 420

DFEMNLGSKV SDGPGAKYLK SNFRSQQNRH SFVEGKTNTL QSGDKHSRHN YMEAHSSTPS 480

SSKFAYLNLS KSYGTLSDAK SVGNLNDVHL YADEPTSRYF PSSCLDLTAP GSPAARRVER 540

LGPGTGGRGS MRSERESNTL DSSYRRSSTR HKTSEESKSP DSLDPGESER SHSHSLSAPH 600

DPLSYGQGYT SPFSSQQRPH RHSMYVRRDH QRTHGGDEGL LVGQGIPTRA SSLQLLSPQL 660

QHRTLPRHSG GSSREEDMSR NEQAPTEVTH SRPPIRDSTR DNTASFHTQR KKSEVGLYHD 720

QQTEDGGSSK ENRNIYSESM PRRVGSFYRV PSPRPDNSFH DSRGQGRGSG LSGDGGSLAN 780

HSKRQPAFDP WTGPDTVVLN ASEPSKEKEK QGFFRAIKKK KKKSQMVSGE GVDTVIQKSS 840

RSSSHQSNRH RSRDKSRDRD QDRDRDKDWP PEKLSDSHSS SQPLKSLRKL LHLSSSSSNQ 900

TASSDMRYQP LPNSASAQGG FTESRGHSGV STPQLKARQS AYPLPGQLDS GWHTSALGRP 960

EGNPYPEQMS IKGGQNGHGF GRPSRSRMPN LNDLKETAL 999

Nucleotide Sequence
(FASTA)

TTTATGATTT CAAAGATAGG GGATGTACTT AATATGATTC ATGTGATGAC CATCTTATTG 60

GAGTTATTTG CTGGTTTATT AATTCTGATA TTAAAGACCA AAATGAAGGA CACCAATGAA 120

ATTGTGGCCA TTAAGAAATT CAAGGACAGC GAAGAAAATG AAGAGGTCAA AGAAACGACC 180

CTGCGGGAGC TCAAAATGCT CCGCACCCTC AAGCAGGAGA ATATTGTTGA GCTGAAAGAA 240

GCCTTCCGCC GAAGAGGGAA GCTGTACCTT GTTTTCGAAT ATGTGGAGAA GAATATGCTC 300

GAGCTGCTCG AGGAGTTACC AAACGGTGTG CCGAGTGAAA AAGCGCGCAG CTACATCTTC 360

CAGCTAATCA AAGCAATTCA CTGGTGCCAT AAGCATGACA TTGTTCACCG AGACATAAAG 420

CCAGAAAACC TTCTCATCAG CTCCGATGAC GTCCTCAAGT TATGTGACTT CGGCTTTGCA 480

CGTAATCTCT CTGAGGGGAC TGACGCCAAT TACACCGAGT ATGTGGCCAC TAGATGGTAC 540

CGGTCTCCGG AGCTCCTGCT CGGGGCTCCT TACGGGAAGG CGGTGGACAT GTGGTCAGTG 600

GGCTGCATCT TAGGAGAGCT GAGTGACGGG CAGCCGCTGT TCCCGGGAGA GAGCGAGATC 660

GACCAGCTCT TTACCATCCA GAAAGTGCTG GGACCCCTGC CACCAGAGCA GATGAAGCTC 720

TTCTATAACA ACCCTCGCTT CCACGGGCTG AGGTTTCCTA CTGTTAGTCA CCCTCAAACC 780

TTGGAGCGAA GATACCTGGG AATCATCGAC GCAGCCCTGC TCGACCTGCT GAAGAACATG 840

CTGCTCCTGA ACCCCACCGA GCGCTTTCTC ACAGAGCAGA GCCTGAACCA CCACGCCTTC 900

CAGACCCTGC GGATGGTAGA GCGGCCTGGG CCACCCACAC CCACACCTGT ACGCTCCTCT 960

AAGAGAAAAC CTCACCACGG AGACAACACT ACCCCCAGCA GGAGCCACGG GGGAAAGAGC 1020

TCAGGAAGCC ACCGCTCCAG CAGCAGAGAG TGCTCCAGCT TACCCCGACA TGAGGACCTC 1080

CACCCCAACA ATGACAGCTT TCTCAACGGC AACATGTCTG CAGCCATCAA CCTCAGCCCC 1140

ACACTGCATC CTAAGAACTA CCAGCCGCAG ATCTTCAACC ACTCCACTGC CTGCAGCATG 1200

GACCTGGCCA GCAGCAACCT GCCTCATCTG CTCAGCCCCG GTGAGACCAA GTCTAAGGGC 1260

GACTTTGAGA TGAACTTGGG GTCCAAGGTG TCAGATGGCC CAGGGGCGAA GTACCTCAAA 1320

TCCAACTTCC GCTCACAGCA GAACCGCCAC TCTTTTGTAG AAGGGAAGAC CAACACGCTT 1380

CAGTCAGGGG ACAAACACAG CCGACACAAC TACATGGAGG CCCACAGCTC CACGCCGTCC 1440

TCCTCTAAGT TTGCCTACCT GAACTTGTCC AAGAGCTATG GCACGCTTAG CGATGCCAAG 1500

TCAGTGGGGA ACTTAAATGA TGTGCATCTT TATGCAGATG AACCCACATC TCGCTATTTT 1560

CCTTCCAGCT GCCTCGACCT CACAGCTCCG GGCAGCCCAG CGGCCCGCCG AGTGGAGAGG 1620

CTGGGACCTG GCACAGGTGG CCGAGGAAGT ATGCGCTCAG AGAGAGAGAG CAACACTCTG 1680

GACTCCTCCT ACAGGCGCTC CTCCACCCGC CATAAAACTT CAGAGGAGTC TAAGTCACCG 1740

GACTCCCTGG ATCCTGGGGA GAGCGAAAGG AGCCATTCCC ATTCTCTGTC TGCCCCACAT 1800

GACCCTCTGT CTTATGGTCA GGGATACACT AGCCCCTTCT CCTCCCAGCA GAGGCCACAC 1860

CGCCACTCCA TGTACGTACG GAGGGATCAT CAGAGGACGC ACGGGGGAGA CGAGGGACTT 1920

TTGGTCGGGC AGGGAATACC CACCAGAGCC AGCAGCCTCC AGCTCCTGTC CCCACAGCTG 1980

CAGCACCGCA CGCTGCCTCG CCACTCTGGG GGCTCTTCCA GAGAAGAAGA CATGAGCAGG 2040

AACGAACAGG CACCCACTGA GGTCACCCAC AGCAGACCTC CAATAAGGGA CTCCACAAGG 2100

GACAACACCG CATCTTTTCA CACACAGCGG AAAAAAAGCG AGGTTGGCTT ATATCATGAC 2160

CAGCAAACAG AAGATGGGGG TTCTTCCAAA GAGAACCGCA ACATCTACAG CGAATCCATG 2220

CCAAGGCGGG TGGGCAGCTT CTACAGAGTC CCATCTCCCC GGCCAGACAA CTCCTTCCAC 2280

GACAGCCGGG GTCAGGGTCG GGGCTCGGGC TTGTCTGGGG ACGGCGGCAG TTTGGCGAAT 2340

CACTCCAAAC GACAGCCGGC TTTTGACCCC TGGACTGGCC CAGATACTGT AGTCTTGAAT 2400

GCCTCTGAGC CTTCCAAAGA AAAGGAGAAG CAGGGTTTCT TCAGAGCAAT AAAGAAGAAA 2460

AAGAAGAAAT CTCAGATGGT TTCCGGTGAA GGCGTGGATA CGGTCATCCA AAAGTCCTCC 2520

AGGTCTTCGA GTCACCAGAG CAACCGCCAC AGGTCACGTG ACAAGAGCAG AGACCGGGAC 2580

CAAGACCGAG ACAGGGACAA GGACTGGCCG CCTGAGAAAC TGTCCGATTC CCACTCTTCG 2640

AGCCAACCGC TGAAGTCGCT GCGCAAGCTC CTGCACCTTT CCTCCTCATC CTCCAACCAG 2700

ACCGCATCTT CTGACATGCG CTACCAGCCG CTGCCTAATT CAGCCTCTGC TCAAGGTGGT 2760

TTCACCGAGA GCCGGGGTCA CTCAGGGGTC AGCACGCCCC AGCTCAAGGC CCGACAGTCA 2820

GCGTACCCGC TGCCTGGACA GCTGGATTCC GGCTGGCACA CGTCCGCCCT GGGCCGCCCC 2880

GAGGGCAACC CCTACCCGGA GCAAATGAGC ATCAAAGGAG GCCAGAACGG GCACGGCTTC 2940

GGACGCCCGT CCAGATCTCG TATGCCAAAT CTCAACGACC TGAAAGAGAC AGCTCTGTGA 3000

Domain Profile

S: 14    vvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenlvnllevfrrkkkl  73

         ++lk + kdt++ivaikkf++se+++evk+++lre+k+l++lk+en+v+l+e+frr+ kl

Q: 29    LILKTKMKDTNEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKL  88

         689*********************************************************

S: 74    ylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknniihrdikpenilisk  133

         ylvfeyv+k++l+ le+ pnGv++e+ +++++q++kai++chk++i+hrdikpen+lis

Q: 89    YLVFEYVEKNMLELLEELPNGVPSEKARSYIFQLIKAIHWCHKHDIVHRDIKPENLLISS  148

         ************************************************************

S: 134   sgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGksvdvwaiGcllael  192

         ++v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGk+vd+w++Gc+l el

Q: 149   DDVLKLCDFGFARNLSeGTDANYTEYVATRWYRSPELLLG-APYGKAVDMWSVGCILGEL  207

         ***************978899*******************.9******************

S: 193   ltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpevedleslekkyp.  251

         ++G+plfpg+s++dql++i+k+lG+l p+++k+f++n++f+G+++p+v+++++le++y

Q: 208   SDGQPLFPGESEIDQLFTIQKVLGPLPPEQMKLFYNNPRFHGLRFPTVSHPQTLERRYLg  267

         **********************************************************97

S: 252   klnevlldllkkclkldpaerlsceellkheyf  284

          ++ +lldllk++l l+p+er+++e+ l+h+ f

Q: 268   IIDAALLDLLKNMLLLNPTERFLTEQSLNHHAF  300

         88999*************************987

Domain Sequence
(FASTA)

LILKTKMKDT NEIVAIKKFK DSEENEEVKE TTLRELKMLR TLKQENIVEL KEAFRRRGKL 60

YLVFEYVEKN MLELLEELPN GVPSEKARSY IFQLIKAIHW CHKHDIVHRD IKPENLLISS 120

DDVLKLCDFG FARNLSEGTD ANYTEYVATR WYRSPELLLG APYGKAVDMW SVGCILGELS 180

DGQPLFPGES EIDQLFTIQK VLGPLPPEQM KLFYNNPRFH GLRFPTVSHP QTLERRYLGI 240

IDAALLDLLK NMLLLNPTER FLTEQSLNHH AF 272

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>