EKS-ORN-00374

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00374

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	389.3	1.1E-116	563	824	262

Status

Unreviewed

Ensembl Protein

ENSONIP00000004111

UniProt Accession

I3J5H1;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000003276	ENSONIP00000004111	ENSONIT00000004112

Organism

Oreochromis niloticus

Functional Description

Protein Length

953

Protein Sequence
(FASTA)

SRNSLQGITI NPPPPCGGPD TVGGVRSVTL PESLLFVSTL DGSLHAVSKQ TGDIKWTLRE 60

DPIIQVPVYL TEPGFLPDPN DGSLYVLGGK HKEGLMKLPF TIPELVQAAP CRSSDGILYT 120

GKKQDVWFVV DPETGEKQTS LTTSTSDSIC PNSPLLYIGR TEYVVTMFDT KTQELRWNAT 180

YNDYSAPPYD EKQDYKMAHL VSSGDGLVVT VDRESGDVLW SQNYGSPVIG VYLYSGDSLR 240

HAPHLSLAME TLRFLTFSSV GNQADAHSTL KWSYQFVKEQ ATAQTQLVPT LYVGKLDSHL 300

YASTSLVHHG VSLVPRGLTL ARLDGPLTAE VTVRERGECE ITPSTDVRYP PGSINSQKNH 360

WLLIGHHELP PVAHTTMLRD FPTTLQHSGE AVIPPRSSPS PVSQFQTLAG RHSDAKATQG 420

GADGKTSGQG QRSATVLPLY VTQDRLTLAV MTLLLGGWLA FMFTYPIQLK AQRQLEEAFE 480

SRLQRMQTNT QAQTLVSSDP PPSTDANISS DPLPASTEPP PSPHSRSNSS SISNTSHGDK 540

KGKNGHKPTA GNSEEVHVGK ISFSPSEVLG HGSAGTFVFR GKFDDRLVAV KRILPECFEV 600

AEREVQLLRE SDTHPNVIRY FCTERDRLFT YIAIELCTAT LQQYVEDPSS FPELSPITLL 660

EQTMCELTFL PSFIRLVHRD LKPRNILLSG PSALGRVRAL ISDFGLCKKI PDGRSSFSLR 720

SGIPGTEGWI APEVLRDNPE NKPTTAVDVF SAGCVFYYVI SRGQHPFGDA LRRQVNILSG 780

EYSLSHFMED LHDDVIAQDL IEQMISAEVE SRPSTACVLK HPFFWSPEKQ LLFFQDVSDR 840

IEKEPADSPI VVRLETAGRL VVRTNWRMHI SVPLQTDLRR FRTYKGNSVR DLLRAMRNKK 900

HHYHELPPEV QETLGELPEG FVGYFTSRFP RLLMHTHAAL QICAHERLFH PYY 953

Nucleotide Sequence
(FASTA)

AGCAGAAACT CACTGCAGGG CATTACAATC AACCCCCCAC CCCCCTGTGG TGGACCTGAC 60

ACAGTTGGTG GGGTCAGATC AGTCACCCTT CCAGAGTCCC TCCTGTTTGT CTCCACTCTG 120

GACGGTAGTC TGCATGCTGT CTCCAAACAG ACAGGAGATA TTAAGTGGAC CTTAAGAGAA 180

GACCCCATTA TTCAAGTTCC TGTCTACCTC ACAGAACCAG GTTTCCTCCC AGACCCCAAT 240

GATGGCAGTT TATATGTACT CGGTGGAAAG CACAAGGAAG GTTTGATGAA GCTGCCTTTT 300

ACCATCCCTG AGCTGGTGCA GGCAGCTCCC TGCAGGAGCT CTGATGGGAT ACTCTATACA 360

GGTAAAAAGC AGGATGTGTG GTTTGTGGTG GATCCTGAAA CCGGTGAAAA GCAAACCAGT 420

TTAACAACCT CCACCTCCGA CTCCATCTGT CCCAACAGTC CTTTGCTCTA CATTGGACGC 480

ACAGAATATG TTGTTACCAT GTTTGATACG AAGACGCAAG AGCTGCGATG GAACGCCACG 540

TACAACGATT ACTCTGCTCC GCCTTACGAC GAGAAGCAAG ACTACAAAAT GGCCCATCTT 600

GTTTCCAGTG GTGATGGTCT TGTTGTGACA GTTGACAGAG AGTCAGGTGA CGTCCTATGG 660

AGTCAGAACT ATGGGTCACC AGTGATCGGC GTCTACCTGT ACTCTGGAGA CTCGCTGAGA 720

CACGCCCCCC ACCTGTCCCT TGCAATGGAA ACACTGCGTT TTCTCACATT CTCATCTGTT 780

GGGAACCAGG CAGATGCACA CTCCACTTTG AAGTGGAGCT ATCAGTTTGT GAAGGAGCAA 840

GCCACTGCAC AGACTCAGCT TGTGCCCACT CTCTATGTGG GAAAGCTGGA CTCCCACCTC 900

TACGCCTCGA CTTCTCTTGT CCACCACGGA GTCTCATTAG TGCCTCGGGG ACTGACCCTG 960

GCACGGCTCG ACGGTCCACT GACGGCTGAG GTGACGGTCA GAGAGAGAGG GGAGTGTGAG 1020

ATCACACCAT CCACCGATGT GCGCTATCCT CCGGGGAGCA TAAACAGCCA GAAAAACCAC 1080

TGGCTACTTA TAGGTCACCA TGAGCTCCCT CCAGTAGCCC ACACGACCAT GTTGAGAGAT 1140

TTTCCCACCA CCCTGCAGCA TTCTGGTGAG GCGGTCATCC CCCCTCGATC TTCTCCCTCC 1200

CCTGTTTCTC AGTTTCAAAC ATTAGCTGGC AGACATAGTG ACGCTAAGGC TACCCAAGGA 1260

GGAGCTGATG GGAAGACATC AGGACAGGGT CAGAGGTCAG CCACCGTGCT GCCTCTCTAT 1320

GTGACTCAGG ACCGTCTGAC TCTGGCTGTC ATGACTCTGC TGCTGGGAGG ATGGCTCGCC 1380

TTCATGTTCA CATATCCCAT CCAGTTGAAA GCTCAAAGAC AGCTGGAGGA GGCCTTTGAG 1440

TCTCGTCTCC AGCGCATGCA GACAAATACG CAGGCACAAA CCTTGGTTTC TTCGGACCCA 1500

CCTCCTTCTA CTGATGCAAA CATCTCAAGC GACCCGTTAC CTGCATCTAC AGAACCTCCA 1560

CCTAGTCCTC ACAGTCGCAG CAACAGCAGC AGCATCAGCA ACACCTCACA TGGAGATAAA 1620

AAAGGCAAGA ATGGACACAA ACCCACAGCA GGAAACAGTG AGGAGGTGCA CGTGGGTAAA 1680

ATCTCCTTCA GTCCCTCTGA GGTGCTCGGA CACGGCTCTG CAGGAACTTT TGTCTTCAGG 1740

GGTAAATTTG ACGACCGCCT CGTTGCTGTG AAGCGAATTC TGCCAGAGTG TTTCGAGGTG 1800

GCAGAGCGAG AGGTGCAGCT CCTCCGAGAG TCCGACACTC ACCCCAACGT CATCCGATAC 1860

TTCTGCACAG AGCGAGACCG CCTCTTCACC TACATCGCCA TCGAGTTGTG CACCGCAACT 1920

CTGCAACAGT ATGTGGAAGA TCCGTCCTCC TTTCCTGAGC TGAGTCCTAT AACTCTGCTG 1980

GAACAGACCA TGTGTGAACT TACATTTCTT CCATCCTTTA TCCGTCTAGT CCATCGTGAC 2040

CTGAAGCCTA GAAACATCCT GCTTTCTGGG CCGAGCGCAC TGGGTCGGGT CCGAGCTCTC 2100

ATCTCGGATT TTGGGCTGTG TAAGAAGATT CCCGATGGTC GGAGCAGCTT CTCTTTGCGG 2160

TCTGGAATAC CAGGAACTGA AGGGTGGATA GCTCCTGAAG TGCTGCGAGA TAACCCTGAA 2220

AATAAACCGA CAACAGCCGT GGATGTGTTT TCAGCAGGCT GCGTGTTTTA CTATGTAATC 2280

AGCAGGGGGC AGCACCCCTT TGGCGATGCA CTGAGAAGAC AGGTCAACAT CCTGTCAGGA 2340

GAGTATTCGC TCTCACACTT TATGGAGGAT TTACATGATG ATGTCATAGC ACAGGATCTG 2400

ATAGAGCAGA TGATCAGTGC TGAGGTGGAG TCACGCCCTT CCACCGCCTG CGTGCTCAAA 2460

CATCCGTTCT TCTGGAGCCC CGAGAAGCAG CTGCTATTTT TCCAGGATGT GAGTGACCGC 2520

ATAGAGAAGG AGCCTGCAGA CAGTCCAATT GTAGTCAGAT TAGAAACTGC AGGAAGATTA 2580

GTCGTCCGAA CCAACTGGAG GATGCACATC TCCGTGCCTC TGCAGACAGA CTTGAGGCGG 2640

TTCAGGACCT ATAAAGGAAA CTCTGTGAGA GACCTGCTGA GAGCCATGAG GAATAAGAAG 2700

CATCACTACC ACGAGCTCCC ACCAGAGGTG CAGGAGACTC TTGGTGAGCT GCCCGAAGGC 2760

TTCGTCGGGT ACTTCACATC ACGGTTTCCA CGGTTACTGA TGCACACACA CGCTGCTCTG 2820

CAAATCTGTG CCCATGAAAG ACTGTTTCAC CCTTACTAC 2859

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         fsp++vlG+G+ Gt+vfrG+f++r vavkr+l+e++++a+rev+llresd+hpnviryfc

Q: 563   FSPSEVLGHGSAGTFVFRGKFDDRLVAVKRILPECFEVAEREVQLLRESDTHPNVIRYFC  622

         789*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhs.lkivhrd  119

         te+dr f yia+elc+a+lq+yved++     el pi+ll+q++  l+ l s +++vhrd

Q: 623   TERDRLFTYIAIELCTATLQQYVEDPSSF--PELSPITLLEQTMCELTFLPSfIRLVHRD  680

         ************************99765..79*****************99469*****

S: 120   lkpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltk  179

         lkp+nil+s p+a g++r+lisdfGlckk++ G+ssfs rsg++GteGwiape+l++ ++

Q: 681   LKPRNILLSGPSALGRVRALISDFGLCKKIPDGRSSFSLRSGIPGTEGWIAPEVLRDNPE  740

         ************************************************************

S: 180   erltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedl  239

         +++t+avd+fs+Gcvfyyv+s+G+hpfGd l+rq nilsge+sl+++ e+ +++via+dl

Q: 741   NKPTTAVDVFSAGCVFYYVISRGQHPFGDALRRQVNILSGEYSLSHFMEDLHDDVIAQDL  800

         ************************************************************

S: 240   iskmidkdplkrpsakkvlkhplf  263

         i++mi+ +  +rps+ +vlkhp+f

Q: 801   IEQMISAEVESRPSTACVLKHPFF  824

         ***********************9

Domain Sequence
(FASTA)

FSPSEVLGHG SAGTFVFRGK FDDRLVAVKR ILPECFEVAE REVQLLRESD THPNVIRYFC 60

TERDRLFTYI AIELCTATLQ QYVEDPSSFP ELSPITLLEQ TMCELTFLPS FIRLVHRDLK 120

PRNILLSGPS ALGRVRALIS DFGLCKKIPD GRSSFSLRSG IPGTEGWIAP EVLRDNPENK 180

PTTAVDVFSA GCVFYYVISR GQHPFGDALR RQVNILSGEY SLSHFMEDLH DDVIAQDLIE 240

QMISAEVESR PSTACVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Canis familiaris"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mustela putorius furo"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013