EPS-ORN-00078

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORN-00078

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	247.0	1.9E-73	192	366	175

Status

Unreviewed

Ensembl Protein

ENSONIP00000005989

UniProt Accession

I3JAU9;

Protein Name

Protein Synonyms/Alias

Gene Name

TPTE

Gene Synonyms/Alias

TPTE;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000004760	ENSONIP00000005989	ENSONIT00000005993

Organism

Oreochromis niloticus

Functional Description

Protein Length

512

Protein Sequence
(FASTA)

MSSVYFNPGS DSSVNGNITK MENAKVEIDD GKEESALPDT LYYNLRKKIA PFVMSFGFRL 60

FGVILIIVDF VLVIVDLSLP AKSRDAGNAL EAVSLTISFF FLADVLLRVY VEGFKVYFSS 120

KLNIIDACVV IVTLAVTMVY TFSDLSGTSL IPRVVTFLRF LRIIILVRVF RLAAQKKELE 180

KVTRRMISEN KRRYQKDGFD LDLTYVTDRV IAMSFPSSGK QAFYRNPIRE VARFLDTKHE 240

GHYKVYNLCS EKGYDPQFFH YRVERVFIDD HNVPSLEDML KYTASVREWM SADPQNIIAI 300

HCKGGKGRTG TMVCTWLIDS DQFESAQDSL EYFGERRTDK SQSSKFQGVE TPSQSRYVGY 360

YEIMKNKLNR QLPPPKSLRI KSIRIHSIAG VGKGNGSDFK VKIVVRKELV FECVCAKQEN 420

CTVFPDVGNN AAVISLQNGP VVEGDVKVMF ESSAGLPKGY EDVPFYFWFN TSFIEDNKLF 480

LPREELDNPH KPKTWDLYKE DFGVTMYFSE SE 512

Nucleotide Sequence
(FASTA)

ATGTCCTCTG TGTACTTTAA CCCAGGCTCA GACTCAAGTG TAAATGGAAA CATTACAAAG 60

ATGGAGAATG CTAAAGTAGA GATTGACGAT GGAAAGGAGG AGAGTGCACT ACCAGACACA 120

CTGTACTACA ATCTTCGGAA AAAAATAGCC CCGTTTGTCA TGTCCTTTGG CTTTCGTTTA 180

TTTGGAGTAA TACTGATCAT AGTGGACTTT GTGCTGGTGA TTGTGGATCT CTCACTGCCA 240

GCCAAGAGTA GAGATGCTGG AAATGCGTTA GAGGCTGTGT CCCTCACCAT CTCTTTCTTC 300

TTCCTTGCCG ATGTCCTCCT GCGTGTCTAT GTGGAGGGTT TCAAAGTGTA CTTCAGCTCC 360

AAGCTGAACA TCATAGACGC CTGCGTGGTG ATAGTCACAC TGGCGGTCAC CATGGTCTAC 420

ACCTTCTCTG ACCTGTCAGG TACCAGCCTT ATCCCCAGGG TTGTGACATT TCTCCGCTTC 480

TTGAGAATAA TAATCCTCGT GAGGGTTTTC AGATTGGCTG CTCAGAAGAA AGAGCTGGAG 540

AAAGTCACCA GGAGGATGAT TTCTGAAAAC AAGCGGCGTT ATCAGAAGGA TGGATTTGAC 600

CTTGATCTTA CCTATGTCAC AGACCGTGTC ATCGCCATGT CTTTCCCCTC CTCTGGGAAG 660

CAGGCCTTCT ATAGGAATCC AATCAGGGAA GTGGCAAGGT TTCTAGACAC TAAACATGAA 720

GGCCATTATA AAGTTTACAA TCTTTGCAGT GAGAAAGGCT ACGACCCCCA GTTCTTCCAC 780

TACAGGGTTG AACGGGTGTT TATTGATGAC CACAATGTCC CCTCCTTGGA GGACATGCTC 840

AAATACACAG CGAGCGTGAG AGAGTGGATG TCTGCTGATC CTCAAAACAT CATTGCGATC 900

CACTGTAAAG GAGGGAAAGG ACGCACTGGT ACTATGGTGT GTACCTGGCT TATTGACAGT 960

GACCAGTTTG AGAGTGCACA GGACAGTCTG GAGTATTTTG GCGAGCGGAG GACGGACAAA 1020

AGTCAGAGCT CCAAGTTTCA GGGGGTGGAG ACTCCCTCTC AGAGCCGGTA CGTGGGGTAC 1080

TATGAGATCA TGAAGAATAA GCTCAACAGA CAATTACCTC CACCGAAAAG CCTCAGGATT 1140

AAAAGCATCC GTATCCACTC CATAGCAGGC GTTGGTAAAG GTAACGGTAG CGATTTCAAG 1200

GTCAAGATAG TTGTGAGAAA AGAGCTGGTG TTTGAGTGTG TGTGCGCCAA GCAGGAGAAC 1260

TGCACGGTGT TTCCTGATGT GGGTAATAAC GCAGCAGTCA TCAGCCTGCA GAATGGGCCT 1320

GTGGTTGAAG GAGACGTGAA GGTCATGTTT GAATCGAGTG CAGGCCTCCC GAAAGGATAT 1380

GAAGATGTTC CATTCTACTT CTGGTTCAAT ACATCCTTCA TAGAAGATAA CAAGTTGTTT 1440

TTACCCAGGG AAGAGCTGGA TAACCCACAC AAACCAAAGA CCTGGGACCT GTACAAGGAA 1500

GACTTTGGTG TCACTATGTA CTTCTCAGAA TCTGAATAA 1539

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+++dgfdldltyvt+r+ia+sfP+++++ +yrn++rev+r+ld kh+++yk+ynlcse

Q: 192   RRYQKDGFDLDLTYVTDRVIAMSFPSSGKQAFYRNPIREVARFLDTKHEGHYKVYNLCSE  251

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         + yd++ ++ +v+++ i+d+n+P+le +  ++  + eW+s+d++n++++hckggkgr+G+

Q: 252   KGYDPQFFHYRVERVFIDDHNVPSLEDMLKYTASVREWMSADPQNIIAIHCKGGKGRTGT  311

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllk  172

         +vc++l+ s+ + +a+++l++fgerr    ++ k++gv++Psq ryv y+  +++

Q: 312   MVCTWLIDSDQFESAQDSLEYFGERRtdkSQSSKFQGVETPSQSRYVGYYEIMKN  366

         **************************6555789*****************98775

Domain Sequence
(FASTA)

RRYQKDGFDL DLTYVTDRVI AMSFPSSGKQ AFYRNPIREV ARFLDTKHEG HYKVYNLCSE 60

KGYDPQFFHY RVERVFIDDH NVPSLEDMLK YTASVREWMS ADPQNIIAIH CKGGKGRTGT 120

MVCTWLIDSD QFESAQDSLE YFGERRTDKS QSSKFQGVET PSQSRYVGYY EIMKN 175

Keyword

Complete proteome; Ion transport; Ionic channel; Membrane; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013