EKS-ORN-00428

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00428

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	316.7	1.5E-94	28	281	254

Status

Unreviewed

Ensembl Protein

ENSONIP00000007020

UniProt Accession

I3JDS9;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK1 (1 of 2)

Gene Synonyms/Alias

TAOK1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000005582	ENSONIP00000007019	ENSONIT00000007024
ENSONIG00000005582	ENSONIP00000007020	ENSONIT00000007025

Organism

Oreochromis niloticus

Functional Description

Protein Length

1016

Protein Sequence
(FASTA)

MPSSVRAGSL KDPEVAELFF KEDPEKLFSD LREIGHGSFG AVYFARDVRT NEVVAIKKMS 60

YSGKQSNEKW QDIIKEVKFL QRIRHPNSIE YKGCYLREHT AWLVMEYCLG SASDLLEVHK 120

KPLQEVEIAA ITHGALQGLA YLHSHNMIHR DVKAGNILLT EPGQVKLADF GSASIASPAN 180

SFVGTPYWMA PEVILAMDEG QYDGKVDVWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

ESPTLQSSEW SEDFRNFIDS CLQKIPQDRP HSDDMLGHEF LQRERPDSVL MDLIQRTKDA 300

VRELDNLQYR KMKKILLQEA HNGPTSEAQD GDEDLEPGGG RTGTVNSVGS NQSIPSMSIS 360

ASSQSSSVNS LNEAAQDSRS ELDLMEGDHT VMSNSSVIHL KPEEEESLSL EQAATSEPTE 420

PQPTPAQAPR KHYRNREHFA TIRTASLVTR EMQEHEQDSE LREQMSGYKR MRRQHQKHLM 480

ALENKLKGEM DEHRLRLDKE LESQRNNFTQ EMEKLLKKHQ AALEKDLKTF ANDEKKFQQH 540

IQVQQKKELS SFLESQKREY KLRKEQLKEE LSENQSTPKK EKQEWLSKQK ENIQHFQAEE 600

EANLLRRQRQ YLELECRRFK RRILIARHNV EQDLAREELN KRQTQKDLEH AMLLRHHESM 660

QELEFRHLAT IQKARAELIR TQHQTELTNQ LEYNKRRERE LRRKHVMEVR QQPKSLKSKE 720

LQIKKQFQET CKTQTRQYKA LRNHLLETTP KSDHKAVLKR LKEEQTRKLA ILAEQYDHSI 780

NEMLSTQALR LDEAQEGECQ VLRMQLQQEL ELLNAYQSKI KMQTDAQHDK ERRELEQRVS 840

LRRALLEQKI EEEMLSLQNE RLERIRSLLE RQAREIEAFD SESMRLGFSN MVLTNLAPDS 900

QGGWGGGGGG GGGQGAQGGG HWPGGGGGGS HHSHHQGGSS SQQSWGHPML AGGPPPWSLH 960

HPGGGSQRGS QGGAGGVRNS PQAMRRTSSG GRSEQGMSRS ASITSQISNG SHLSYT 1016

Nucleotide Sequence
(FASTA)

ATGCCCTCCT CCGTAAGGGC AGGGAGCCTC AAGGATCCGG AGGTGGCTGA GCTTTTCTTC 60

AAAGAAGATC CAGAGAAGCT TTTCTCCGAC CTCCGAGAGA TTGGCCATGG CAGCTTTGGC 120

GCCGTCTACT TTGCTCGGGA TGTGCGCACA AACGAGGTGG TGGCAATTAA AAAGATGTCC 180

TACAGTGGCA AACAGTCTAA TGAGAAATGG CAGGACATCA TAAAGGAGGT GAAGTTCCTC 240

CAAAGGATCC GGCACCCCAA CAGTATAGAA TATAAAGGAT GTTACCTCCG CGAGCACACA 300

GCATGGCTGG TGATGGAGTA CTGTCTTGGC TCGGCCTCTG ACCTGCTAGA AGTTCATAAA 360

AAACCTTTAC AAGAAGTTGA GATTGCTGCC ATCACACATG GTGCTCTGCA GGGGCTGGCC 420

TACCTTCATT CCCATAATAT GATCCACAGG GATGTGAAAG CTGGCAACAT CCTGCTGACT 480

GAGCCTGGCC AAGTCAAACT GGCAGATTTT GGCTCTGCCT CCATTGCCTC ACCTGCCAAC 540

TCTTTTGTGG GAACGCCATA TTGGATGGCC CCAGAGGTGA TTCTAGCTAT GGATGAAGGC 600

CAGTATGATG GAAAGGTGGA CGTCTGGTCC TTAGGGATTA CCTGTATAGA ATTAGCGGAG 660

AGGAAGCCTC CCTTGTTTAA CATGAATGCA ATGAGTGCCT TATACCACAT AGCGCAGAAT 720

GAGAGCCCCA CACTGCAGTC CAGTGAATGG TCAGAAGATT TTAGAAACTT TATCGATTCT 780

TGCCTTCAGA AAATCCCCCA GGACCGACCG CACTCTGACG ACATGTTAGG TCACGAGTTT 840

CTGCAACGTG AGCGTCCAGA CTCTGTGCTG ATGGACCTCA TTCAGAGAAC CAAGGATGCC 900

GTACGAGAGC TGGATAACCT GCAGTACCGA AAGATGAAGA AGATCCTCCT TCAGGAGGCC 960

CACAATGGGC CCACTTCAGA AGCCCAGGAT GGAGACGAGG ACCTGGAGCC TGGTGGAGGT 1020

CGGACAGGAA CGGTGAACAG CGTTGGCAGT AATCAGTCCA TCCCCAGCAT GTCTATCAGC 1080

GCTAGCTCCC AGAGCAGCTC TGTCAACAGC CTGAATGAAG CAGCTCAGGA CAGCCGCAGT 1140

GAGCTGGACC TAATGGAAGG AGATCACACA GTCATGTCCA ACAGCTCCGT CATACACCTC 1200

AAACCGGAGG AAGAAGAGAG TCTCTCTTTG GAACAAGCAG CCACCAGTGA GCCCACTGAG 1260

CCCCAGCCAA CACCAGCTCA GGCCCCGAGG AAGCACTACC GCAACAGAGA GCACTTTGCC 1320

ACTATACGCA CAGCATCACT TGTGACACGT GAGATGCAAG AACACGAGCA GGACTCGGAG 1380

CTGAGGGAGC AGATGTCAGG ATACAAACGC ATGAGGCGGC AACATCAGAA GCACCTAATG 1440

GCCCTGGAGA ACAAGCTGAA AGGGGAAATG GATGAGCACA GGCTGAGGCT GGACAAAGAG 1500

CTGGAGAGTC AGAGGAACAA CTTCACCCAG GAGATGGAGA AGCTGCTTAA AAAACACCAA 1560

GCGGCCCTGG AAAAAGACCT GAAGACGTTT GCCAACGATG AGAAGAAGTT CCAGCAGCAC 1620

ATTCAGGTTC AGCAGAAGAA GGAGCTCAGC AGCTTCTTGG AGTCACAAAA GCGGGAGTAT 1680

AAACTACGCA AAGAGCAGCT CAAAGAGGAG CTGAGTGAGA ACCAGTCAAC TCCCAAGAAA 1740

GAGAAGCAGG AGTGGCTCTC CAAGCAGAAA GAGAACATCC AACACTTCCA GGCTGAGGAG 1800

GAGGCTAACC TGCTGAGGAG ACAGAGGCAG TATCTGGAGC TGGAGTGTAG GCGGTTCAAA 1860

CGCAGGATCC TCATCGCCAG ACACAATGTG GAGCAGGACC TGGCCAGAGA GGAGTTGAAC 1920

AAACGTCAAA CGCAGAAGGA TCTGGAGCAT GCGATGCTGC TGAGGCATCA CGAGTCCATG 1980

CAGGAGCTGG AGTTCAGGCA TCTGGCAACA ATCCAGAAAG CCCGGGCAGA GCTGATACGC 2040

ACCCAGCACC AGACAGAGCT CACAAACCAG CTGGAGTACA ATAAGAGGAG GGAGAGGGAG 2100

CTGAGGCGCA AGCATGTCAT GGAGGTCCGG CAGCAGCCCA AAAGCCTCAA GTCTAAGGAG 2160

CTTCAGATTA AGAAGCAGTT TCAGGAGACC TGCAAAACGC AGACTCGGCA GTATAAGGCC 2220

CTCAGGAACC ATCTGCTCGA GACCACACCC AAGTCCGACC ACAAGGCTGT CCTAAAGAGG 2280

CTGAAGGAGG AGCAGACTAG GAAGCTGGCC ATCCTCGCCG AGCAGTATGA TCACTCCATC 2340

AATGAAATGC TCTCCACACA GGCTCTGCGG TTGGATGAAG CTCAGGAGGG GGAGTGTCAG 2400

GTGCTGAGGA TGCAGCTGCA GCAGGAGCTT GAGCTGCTCA ATGCATACCA GAGCAAAATC 2460

AAGATGCAGA CAGACGCACA GCACGACAAG GAGAGAAGGG AGCTGGAGCA GAGGGTGTCT 2520

CTGCGGCGGG CTCTGCTGGA GCAGAAAATC GAGGAGGAGA TGCTTTCCCT GCAAAACGAG 2580

CGTCTGGAGC GAATCCGCTC ACTGCTGGAG CGCCAGGCCC GAGAGATCGA GGCTTTTGAC 2640

TCGGAGTCCA TGCGACTGGG CTTCAGCAAC ATGGTGCTCA CTAACCTGGC TCCCGATTCT 2700

CAGGGAGGCT GGGGTGGAGG AGGAGGAGGA GGAGGAGGCC AGGGGGCTCA GGGGGGGGGC 2760

CACTGGCCGG GAGGAGGTGG AGGAGGCAGT CACCATAGTC ATCACCAGGG GGGCTCCAGC 2820

TCACAGCAGT CCTGGGGTCA CCCTATGCTG GCTGGGGGCC CACCACCCTG GAGCCTCCAC 2880

CACCCTGGTG GGGGCAGTCA GAGGGGTAGC CAAGGAGGTG CGGGAGGGGT GAGGAACAGC 2940

CCACAGGCTA TGAGGAGGAC GTCATCAGGG GGGAGGAGTG AACAGGGCAT GAGCAGGAGC 3000

GCCAGCATCA CCTCTCAGAT CTCCAATGGA TCCCACCTGT CATACACCTA A 3051

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpn  57

         ++ l+eig+G++g+vy ar+++t+e+vaikk++++ +   ek+++++ke+++l++++hpn

Q: 28    FSDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKqsnEKWQDIIKEVKFLQRIRHPN  87

         67899*****************************988899********************

S: 58    iveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHsk  117

          +ey +++l+e++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+

Q: 88    SIEYKGCYLREHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSH  145

         *********************7.********.****************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekg  176

         ++iHrd+ka+niLlte g+VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +

Q: 146   NMIHRDVKAGNILLTEPGQVKLADFGSASIASP----ANSFVGTPYWMAPEVILAMdEGQ  201

         **************************9988887....69**************9887999

S: 177   YdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvek  236

         Yd k+D+wslGIt+ielae++pP++++++++al++i++ne+p+l+s+ ++s+ f++f+++

Q: 202   YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSS-EWSEDFRNFIDS  260

         ********************************************777.************

S: 237   clqknpekRpsasellkhkFl  257

         clqk p++Rp ++++l h+Fl

Q: 261   CLQKIPQDRPHSDDMLGHEFL  281

         ********************7

Domain Sequence
(FASTA)

FSDLREIGHG SFGAVYFARD VRTNEVVAIK KMSYSGKQSN EKWQDIIKEV KFLQRIRHPN 60

SIEYKGCYLR EHTAWLVMEY CLGSASDLLE VHKKPLQEVE IAAITHGALQ GLAYLHSHNM 120

IHRDVKAGNI LLTEPGQVKL ADFGSASIAS PANSFVGTPY WMAPEVILAM DEGQYDGKVD 180

VWSLGITCIE LAERKPPLFN MNAMSALYHI AQNESPTLQS SEWSEDFRNF IDSCLQKIPQ 240

DRPHSDDMLG HEFL 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013