EKS-ORN-00424

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00424

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	324.5	6.3E-97	17	291	275

Status

Unreviewed

Ensembl Protein

ENSONIP00000007351

UniProt Accession

I3JER0;

Protein Name

Protein Synonyms/Alias

Gene Name

OXSR1 (1 of 2)

Gene Synonyms/Alias

OXSR1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000005836	ENSONIP00000007351	ENSONIT00000007356

Organism

Oreochromis niloticus

Functional Description

Protein Length

534

Protein Sequence
(FASTA)

MSEDLSSQPW SINKDDYELH EVIGSGATAV VQAAYCIPRK EKVAIKRINL EKCQTSMDEL 60

LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDVIKHIISR GEHKTGVLDE 120

ASIATVLRDV LEGLEYLHKN GQIHRDLKAG NILLGDDGSV QIADFGVSAF LATGGDITRN 180

KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL 240

QNDPPSLETG VTDKETVKKY GKSFRKMISL CLQKDPEKRP TSSELLKHKF FQKAKTHEYL 300

HEKLLQRAPT ITERSKRVRR VPGSSGRLHK TEDGEWEWSD DELDEESEEG KAAAAAIRSP 360

RVKEGSQNSE VFQTPEPLSS HLQPPAAGQA ELPQAAGQVP LQPTPATAQS TAQAASPTPG 420

VPAAAVPPQI SAASGDVQAP ISLVLRLRNS KKELNDIRFE FMPGRDTADG VSQELVSAGL 480

VDGRDLVIVA ANLQKIVDEP QTHKNVTFKL ASGIEGSEIP DDIKLMGFAQ LSIS 534

Nucleotide Sequence
(FASTA)

ATGTCGGAGG ACCTGAGCTC CCAACCCTGG TCCATCAACA AAGATGATTA CGAGCTACAC 60

GAGGTGATTG GGAGTGGGGC CACAGCTGTG GTTCAAGCAG CCTACTGTAT ACCACGCAAG 120

GAGAAGGTGG CCATTAAACG CATCAACCTG GAGAAGTGCC AGACCAGCAT GGACGAACTC 180

CTGAAAGAGA TTCAGGCCAT GAGTCAGTGC CACCACCCCA ACATTGTGTC TTACTACACC 240

TCCTTTGTGG TAAAGGATGA GCTGTGGCTG GTTATGAAGC TGCTCAGCGG CGGCTCAGTG 300

CTGGATGTGA TCAAGCATAT CATCTCACGA GGGGAGCACA AGACCGGCGT CCTGGATGAG 360

GCCAGCATAG CCACAGTGTT GAGAGATGTT CTTGAGGGCC TGGAGTACCT ACACAAGAAC 420

GGACAGATCC ACAGAGATCT TAAGGCTGGA AACATCCTCC TCGGGGATGA TGGTTCAGTG 480

CAGATTGCAG ACTTTGGCGT CAGTGCCTTT CTAGCCACGG GAGGTGACAT CACTCGAAAT 540

AAAGTGCGCA AGACTTTCGT GGGAACGCCG TGCTGGATGG CCCCAGAGGT CATGGAGCAG 600

GTGAGGGGTT ATGATTTCAA AGCAGATATT TGGAGTTTTG GGATCACGGC CATTGAGCTC 660

GCTACAGGAG CTGCACCTTA TCACAAATAC CCACCGATGA AGGTCTTAAT GCTGACGCTG 720

CAGAATGACC CTCCGAGTCT GGAGACCGGC GTCACAGATA AGGAGACGGT AAAGAAATAC 780

GGCAAATCCT TCAGGAAGAT GATCTCACTG TGTCTACAGA AAGACCCTGA GAAAAGGCCA 840

ACATCATCAG AGTTGTTGAA GCATAAATTC TTTCAGAAGG CAAAGACACA CGAGTATTTA 900

CACGAGAAGT TGCTTCAGAG GGCGCCGACA ATAACGGAGA GGTCAAAAAG GGTACGTCGA 960

GTGCCAGGCT CCAGCGGTCG GCTGCATAAA ACAGAGGACG GCGAATGGGA GTGGAGCGAC 1020

GACGAGCTCG ATGAAGAGAG CGAAGAAGGC AAAGCAGCTG CTGCAGCCAT ACGGTCACCA 1080

AGAGTGAAGG AGGGATCACA GAATTCAGAG GTTTTCCAGA CTCCTGAGCC TTTAAGTAGT 1140

CATCTCCAGC CTCCGGCCGC AGGTCAGGCT GAACTACCTC AGGCTGCAGG TCAAGTTCCG 1200

CTGCAGCCCA CACCAGCCAC CGCTCAATCT ACTGCCCAGG CTGCATCTCC CACACCAGGA 1260

GTACCTGCTG CTGCTGTTCC CCCTCAGATT TCAGCCGCCT CAGGGGATGT TCAGGCTCCC 1320

ATTAGTTTGG TATTAAGGTT AAGAAATTCA AAGAAGGAGC TAAATGACAT CCGCTTTGAG 1380

TTCATGCCAG GGAGAGACAC AGCAGATGGT GTGTCTCAGG AGCTGGTGTC AGCAGGCCTG 1440

GTGGACGGGA GGGACTTAGT AATAGTTGCT GCAAATTTGC AGAAAATAGT CGATGAACCT 1500

CAAACCCATA AAAATGTCAC TTTCAAACTG GCTTCTGGAA TTGAGGGATC TGAAATACCA 1560

GACGACATCA AGTTGATGGG CTTTGCTCAG CTCAGCATTA GTTAG 1605

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel e+ig+Ga++ v++a++++++e+vaik+inlek+ ++++el kei+++++++hpniv

Q: 17    YELHEVIGSGATAVVQAAYCIPRKEKVAIKRINLEKCqTSMDELLKEIQAMSQCHHPNIV  76

         899**********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E +ia++lr+vl++Ley

Q: 77    SYYTSFVVKDELWLVMKLLSGGSVLDVIKhiisrgEHKTGVLDEASIATVLRDVLEGLEY  136

         *****************************9**99999***********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niLl ++g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 137   LHKNGQIHRDLKAGNILLGDDGSVQIADFGVSAFLATggdiTRNKvRKTFVGTPCWMAPE  196

         ***********************************99999988899**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaDiws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 197   VMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGvtdke  255

         ***5.9********************************************9966666667

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f+++++ clqk+pekRp++sellkhkF+

Q: 256   tvKKYGKSFRKMISLCLQKDPEKRPTSSELLKHKFF  291

         7799*******************************7

Domain Sequence
(FASTA)

YELHEVIGSG ATAVVQAAYC IPRKEKVAIK RINLEKCQTS MDELLKEIQA MSQCHHPNIV 60

SYYTSFVVKD ELWLVMKLLS GGSVLDVIKH IISRGEHKTG VLDEASIATV LRDVLEGLEY 120

LHKNGQIHRD LKAGNILLGD DGSVQIADFG VSAFLATGGD ITRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADIWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPS LETGVTDKET 240

VKKYGKSFRK MISLCLQKDP EKRPTSSELL KHKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013