EPS-ORN-00043

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORN-00043

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	166.8	1.0E-48	721	967	247

Status

Unreviewed

Ensembl Protein

ENSONIP00000007413

UniProt Accession

I3JEX1;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000005888	ENSONIP00000007412	ENSONIT00000007417
ENSONIG00000005888	ENSONIP00000007413	ENSONIT00000007418

Organism

Oreochromis niloticus

Functional Description

Protein Length

1222

Protein Sequence
(FASTA)

STSTTVEELC AQKNGHALYV QLHGDLVRRL DPSERPLQMV YDYLASMGYA DPVRVQQEAA 60

NSDLSCLIRF YSERPVNADQ QERTLLKGVF SVRKGKTQLH KWAERQVILC GTCLIVASVK 120

DSLTGKMHIL PLVGGKVEEV KRRQHCLMFS SAGSQAQTYF VNFDTLADYQ RWHRQASKVV 180

SQTVSLVDLS CYSLEAVPEY LFYSQDITHL NLRHNFMSLQ GPGGLLNLPR FSQLKSLNLS 240

HNRLGVFPEC VCEILTLTEL NLSCNSLRAI PVQIGNLQSL QTLSLDGNHL SSLPEEMGGL 300

FQLNSLGLSF NSFSHVPAVL ERLSAVDKLA MAGNRVESLD LCTLVRMSHL KNIDLRLNGL 360

RWVKSENLEV VSQVTQLDLR DNCLESLDLS SVCNLETLHC QRNQLGTLTL SGFTLRMLHA 420

SSNRLTTVNI YPVPNQLTHM DLSQNLLEYL PDWVCDCRKI EMLDITRNLL SELPSRLCFC 480

INLSLRKLLT GCNRLQRVPE LLDHVPLEAL DLQHNMLAEL PESLFLKALN LKYLNVSANA 540

LESIPPSSQS EESLSTLQEL YLTGNNLSEN CGALLVGHQN LRILHIAYNQ LLSFPASKLS 600

KLELLEELNL SGNNLKTIPS TVSSCKRLHT LIAHSNHISV FPEILNLPEI KLVDLSCNEL 660

TEIQLPDSLP ASLQELDLTG NSSLMLEHKT LNLFSHITTL KLDQKSTTTA GDSLSASTPW 720

KHGYSEMSGQ RNKLCVSVLA VDHFRDSVEA CYGIFDGDRN EEVPRLLQCT MGDVLCEELQ 780

HSSVDSVYMC NTFLTSHRKL GMAGQKLGAS GLLCYIHRET SDPGASFSLT VANVGTCQAV 840

LCRNGQPVPL SKVYSLENCT EEMERVKVSK AIITEDNKVS GVTCCSRLLG CSYLSPWVLP 900

KPWVHTEPLC SQDEFLILGN RALFERVSYQ EAVCTVQAVR DPRAAAKKLC SLAQSYGCKD 960

NIGAVVVSLH IGEDSCTCEP PVTTTEPRGP APAPVPASVI PGPSDPATNL SSSSGIVTEF 1020

SSETSASEIG SEAGSTASDE HPSSGTVTRP ERRCSLHPAT TLCGIMVPGS GLFQQQPSST 1080

TFSSNQSDNG LDSDDEAPLE GVISNGSKLE VEVDIHCCAF QPSGKMRRQN SVVVSATNGC 1140

LLAVCGREIA DLKKSPSTSS LFGKKLSNGS VVAPEDSHNL IEVALEAPKK KSGYFTAPAQ 1200

QDPEDQLIVP PSLEQEVREQ LR 1222

Nucleotide Sequence
(FASTA)

TCCACCAGTA CCACGGTGGA GGAGCTGTGT GCTCAGAAGA ACGGACACGC ACTTTACGTT 60

CAACTGCACG GAGACCTAGT GAGGAGGCTG GATCCCTCTG AGCGTCCGCT CCAGATGGTG 120

TATGACTACT TGGCGTCGAT GGGCTATGCA GACCCTGTAC GAGTGCAGCA AGAAGCCGCC 180

AACTCAGACC TCAGCTGTTT GATCCGTTTC TACAGTGAGC GTCCAGTGAA TGCGGACCAG 240

CAGGAGCGGA CCTTGCTGAA AGGCGTGTTC AGCGTCAGGA AGGGCAAGAC TCAGCTGCAC 300

AAGTGGGCCG AGCGGCAGGT CATTCTCTGT GGCACCTGTT TGATCGTGGC CTCTGTGAAA 360

GACAGCCTCA CCGGGAAGAT GCACATCCTG CCCCTGGTGG GGGGAAAGGT GGAGGAGGTG 420

AAGCGGAGGC AGCACTGTCT GATGTTCAGC TCAGCCGGAT CTCAGGCTCA GACATACTTT 480

GTCAACTTTG ACACACTTGC AGACTATCAG CGATGGCACC GGCAGGCGTC AAAAGTGGTG 540

TCTCAGACGG TAAGCCTAGT GGACTTGTCC TGCTACAGTC TGGAAGCAGT GCCTGAATAT 600

CTGTTTTACA GTCAGGACAT TACCCATCTC AACTTGCGAC ACAACTTCAT GAGCCTGCAG 660

GGACCTGGAG GCCTGCTCAA CCTCCCCAGG TTTTCTCAGC TGAAGAGCCT GAACTTATCT 720

CATAACCGTC TGGGTGTGTT CCCCGAGTGT GTGTGCGAGA TCCTCACCCT AACTGAACTC 780

AACCTCTCCT GTAACAGTCT CCGCGCCATC CCTGTACAGA TAGGCAACCT TCAAAGCCTG 840

CAGACGCTGT CTTTGGATGG AAACCACCTC AGCTCCCTGC CTGAAGAGAT GGGTGGCCTG 900

TTTCAGCTCA ACAGCCTGGG GCTTTCCTTC AACAGCTTCT CTCACGTCCC TGCTGTGCTG 960

GAGAGATTGA GTGCAGTTGA CAAGCTGGCT ATGGCTGGGA ACAGAGTGGA GAGTCTGGAT 1020

TTGTGCACTC TGGTCAGAAT GAGCCACCTG AAAAACATTG ACCTCCGGCT GAATGGATTG 1080

CGGTGGGTGA AAAGTGAGAA TCTAGAGGTA GTGAGCCAGG TGACCCAGCT GGACTTGCGA 1140

GACAACTGCT TAGAATCGCT AGACCTCAGC TCTGTGTGCA ACCTGGAGAC TCTGCACTGC 1200

CAACGCAACC AGCTGGGGAC ACTCACACTC AGCGGTTTCA CACTGCGCAT GCTTCATGCC 1260

AGCAGCAACC GCCTTACAAC AGTCAACATC TATCCAGTCC CTAACCAGCT GACGCACATG 1320

GACCTATCAC AGAACCTCTT GGAGTATCTT CCAGACTGGG TGTGTGACTG CAGAAAAATT 1380

GAGATGCTGG ACATTACACG TAACCTCCTG TCGGAGCTTC CTTCCAGGTT ATGTTTTTGC 1440

ATAAACTTGA GTTTGAGGAA GCTGCTGACG GGGTGCAACC GCTTGCAAAG AGTGCCTGAA 1500

CTCCTTGACC ATGTCCCTCT GGAAGCCCTG GACCTCCAGC ACAACATGCT AGCTGAGCTT 1560

CCAGAGAGTC TGTTTCTGAA GGCCTTAAAC CTGAAATACT TAAACGTGTC AGCCAATGCC 1620

TTGGAAAGCA TTCCGCCGAG CAGCCAATCA GAGGAGAGCC TCAGCACACT CCAGGAGCTC 1680

TACCTGACGG GGAACAACCT GAGCGAGAAC TGCGGCGCTC TGCTGGTCGG ACACCAGAAC 1740

CTGCGGATCC TCCACATTGC CTACAACCAG TTACTCTCAT TCCCTGCCAG TAAGCTAAGT 1800

AAGCTGGAAC TGCTGGAGGA GCTAAATTTA AGCGGCAACA ATCTAAAAAC AATACCCTCC 1860

ACTGTGTCCA GCTGTAAGAG ACTGCACACC CTCATAGCAC ACTCGAACCA CATCAGCGTC 1920

TTCCCAGAGA TCCTCAACCT CCCCGAGATC AAGCTTGTCG ATCTAAGCTG CAATGAGCTC 1980

ACTGAGATCC AGCTGCCCGA TTCCCTGCCT GCCTCTTTAC AAGAGCTGGA CCTGACAGGC 2040

AACAGCAGCC TGATGCTGGA ACACAAAACC CTCAATCTCT TCAGCCACAT CACCACCCTG 2100

AAATTAGACC AGAAATCCAC CACAACAGCA GGAGACTCTC TGAGCGCCTC CACTCCTTGG 2160

AAGCATGGCT ACTCTGAAAT GAGCGGGCAA AGGAACAAGT TGTGTGTGTC TGTGCTGGCT 2220

GTAGACCACT TCAGAGACAG CGTGGAAGCA TGCTATGGTA TCTTTGACGG AGACCGCAAC 2280

GAGGAAGTGC CTCGCCTGTT GCAGTGCACT ATGGGAGACG TGCTGTGCGA GGAGCTGCAG 2340

CACTCCAGTG TTGACAGTGT GTATATGTGC AACACTTTCC TCACCTCACA CAGGAAACTT 2400

GGTATGGCTG GTCAGAAGCT GGGTGCATCT GGCCTGCTGT GTTATATCCA CCGTGAGACT 2460

TCAGATCCAG GAGCATCCTT TAGCCTTACT GTGGCCAATG TGGGTACCTG CCAAGCCGTG 2520

CTGTGCCGAA ATGGACAACC TGTACCTCTC TCTAAGGTTT ACAGTTTGGA GAACTGCACT 2580

GAGGAAATGG AGCGGGTTAA AGTCAGTAAA GCCATTATTA CAGAGGATAA CAAAGTGAGT 2640

GGAGTGACAT GCTGCTCTCG CCTGTTGGGC TGCTCTTATC TGTCTCCCTG GGTGCTTCCA 2700

AAGCCCTGGG TGCACACTGA GCCGCTTTGT TCCCAGGATG AGTTCTTGAT CCTGGGGAAT 2760

CGAGCCCTGT TTGAGCGAGT TTCCTACCAG GAGGCTGTGT GCACCGTGCA GGCTGTCCGG 2820

GATCCCCGTG CTGCTGCTAA GAAGTTGTGT TCACTTGCCC AAAGTTACGG TTGCAAGGAC 2880

AACATCGGAG CTGTCGTGGT GTCCCTGCAC ATTGGTGAGG ACAGCTGCAC ATGTGAGCCG 2940

CCGGTCACCA CCACCGAGCC ACGGGGCCCT GCTCCTGCTC CCGTTCCTGC GTCTGTGATC 3000

CCGGGCCCTA GCGACCCAGC CACCAACCTC TCCTCCAGCA GTGGCATTGT CACTGAGTTC 3060

AGCAGTGAGA CGTCAGCTTC AGAGATCGGC AGCGAAGCGG GGTCCACCGC TTCAGATGAA 3120

CACCCATCCT CTGGCACTGT GACCCGCCCA GAGAGACGCT GTAGCCTACA CCCCGCTACC 3180

ACACTGTGCG GCATCATGGT GCCAGGCTCA GGTCTATTCC AGCAGCAGCC GTCCAGCACC 3240

ACATTCTCAA GTAACCAGTC GGACAATGGC TTGGACAGTG ATGATGAAGC TCCACTCGAG 3300

GGTGTCATCT CCAATGGTAG CAAATTAGAA GTGGAAGTAG ACATTCACTG TTGTGCTTTT 3360

CAGCCCAGTG GTAAAATGCG CAGACAGAAC AGCGTGGTGG TTTCTGCTAC AAACGGCTGC 3420

CTGCTTGCTG TATGTGGGAG AGAGATTGCT GACCTTAAGA AATCTCCCTC CACATCCAGC 3480

CTGTTTGGGA AGAAGTTGTC CAATGGTTCT GTGGTAGCCC CTGAAGACAG TCACAACCTA 3540

ATTGAGGTTG CCCTAGAGGC TCCCAAGAAA AAGTCTGGCT ATTTCACAGC TCCAGCACAG 3600

CAGGACCCAG AGGACCAGCT GATTGTGCCT CCTAGTCTGG AGCAGGAAGT CAGGGAGCAG 3660

CTACGA 3666

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++++g+rn+++ +v ++++f +s e+      +g++DG++++ev + +++++ ++l

Q: 721   KHGYSEMSGQRNKLCVSVLAVDHFRDSVEA-----CYGIFDGDRNEEVPRLLQCTMGDVL  775

         799**********************99885.....8************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          eel+    ++   + ++ ++Fl+ +++l       ++ +k G++ ++++i  +

Q: 776   CEELQ----HSSVDSVYMCNTFLTSHRKL------GMAGQKLGASGLLCYIHREtsdpga  825

         ***99....56666678************......89***************88899999

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcrng++v+ls+ ++ ++  +E+eR++  ++ +++++  +v Gv+

Q: 826   sfSLTVANVGTCQAVLCRNGQPVPLSKVYSLENCtEEMERVKVSKAIITEDN--KVSGVT  883

         9*****************************987549*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         ++sR lG+ yl+p+v p+P v+  +l s+defliL+   l++ vs +eav  v+ v +

Q: 884   CCSRLLGCSYLSPWVLPKPWVHTEPLCSQDEFLILGNRALFERVSYQEAVCTVQAVRD--  941

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +++aakkL+ la+++g+kdn+ a+vv

Q: 942   --PRAAAKKLCSLAQSYGCKDNIGAVVV  967

         ..***********************997

Domain Sequence
(FASTA)

KHGYSEMSGQ RNKLCVSVLA VDHFRDSVEA CYGIFDGDRN EEVPRLLQCT MGDVLCEELQ 60

HSSVDSVYMC NTFLTSHRKL GMAGQKLGAS GLLCYIHRET SDPGASFSLT VANVGTCQAV 120

LCRNGQPVPL SKVYSLENCT EEMERVKVSK AIITEDNKVS GVTCCSRLLG CSYLSPWVLP 180

KPWVHTEPLC SQDEFLILGN RALFERVSYQ EAVCTVQAVR DPRAAAKKLC SLAQSYGCKD 240

NIGAVVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>