EKS-ORN-00352

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00352

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	396.4	1.3E-118	665	981	317

Status

Unreviewed

Ensembl Protein

ENSONIP00000007961

UniProt Accession

I3JGH0;

Protein Name

Protein Synonyms/Alias

Gene Name

PRPF4B

Gene Synonyms/Alias

PRPF4B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000006312	ENSONIP00000007961	ENSONIT00000007966

Organism

Oreochromis niloticus

Functional Description

Protein Length

985

Protein Sequence
(FASTA)

FPFDFSQPNN LALKNRKQDL ESHERSGNED SGDISEEEEE DSSGKHKRKK HKHRSKHKKH 60

KHASDEDKDR KRKHRHKHRK HKRKEGSSPS AAVLFGSSTH RNPSLDDRAL LEDLEKQRAM 120

IKAELDSQLM EGKVQSGMGL ILQGYNSGSE EDGDARFRNG EPRQRGSSGK PISPRGGKSG 180

KSRRDSTEGS KSSSKRRSRS KSADKPAKES KQDKVTKSTK DTGVKDRGRG RSRSKDRKRS 240

HSTDRSKERR KSNSPSSFRA EQKVGRTDKR SSPQRDDRPN QERVSRRSRS PGRERPSRSD 300

ADRDKRPAKS PSKDTSLGKE NRSPHRRGAH SPARKRSASP RHRDARYPSA SASERTSKQS 360

HSPSRTRFSP QRRRSRSPEV RRRDAERQES PLRKRSRADV GPGRDRSRDN SPRSSSRRRM 420

SRSPLRRRSP SPRRRSRSSP RRRSRSPLRR RSGERDRYGR LRQYRRSTSR DRERRRRGRD 480

EDKFKGSLSE GMKVDQESSE EEVLEDFDGE EIDEEALIEQ RRQQRMAIVQ KYKIVNEDTN 540

QTSEPSSPQS STRSRSPSPD DILERVAADV KEYERENLNT FEASIKAKHN LIAQEKDGRS 600

NPKKPSAPDM FTESDDMFAA DFDSARMRAA GVGKDFKENP NLRDNWTDAE GYYRVNIGET 660

LDKRYDVYGY TGQGVFSNVI RARDTARAGQ EVAIKIIRNN ELMHKTGLKE LEFLKKLNDA 720

DPDDKFHCLR LFRHFYHKQH LCLVFEPLSM NLREVLKKYG KDVGLHIKAV RSYSQQLFLA 780

LKLLKRCNIL HADIKPDNIL VNESKTILKL CDFGSASHVA DNDITPYLVS RFYRAPEIII 840

GKPYDYGIDM WSVGCTLYEL YTGKILLPGS SNNHMLKLAM DLKGKMPNKM IRKGLFKDQH 900

FDQNLNFLYI EVDKVTEREK VTVMSTINPT KDLLADMIGG QRLPEDQRKK VMQLKDLLDG 960

TLMLDPAKRI SINQALQHPF IQEKI 985

Nucleotide Sequence
(FASTA)

TTTCCTTTTG ACTTCAGTCA GCCAAATAAT TTAGCACTAA AAAACAGGAA GCAAGATCTG 60

GAAAGCCATG AACGAAGTGG AAATGAGGAC AGTGGCGACA TATCTGAAGA GGAGGAGGAG 120

GACAGTAGCG GTAAACACAA GCGGAAAAAA CACAAGCATC GCAGTAAGCA CAAAAAGCAC 180

AAACATGCCT CTGATGAGGA CAAGGACCGC AAACGCAAGC ATCGTCACAA ACATAGGAAA 240

CACAAACGCA AAGAGGGCTC CTCTCCCTCC GCCGCTGTCC TCTTTGGCTC CTCTACTCAT 300

AGAAATCCAA GTCTGGATGA CAGGGCCTTG CTGGAGGATT TGGAGAAACA GAGGGCCATG 360

ATCAAAGCTG AACTTGACAG CCAGTTGATG GAGGGAAAAG TTCAGTCTGG CATGGGTTTG 420

ATTCTTCAGG GGTATAACTC TGGATCTGAA GAGGATGGAG ATGCAAGGTT CAGAAATGGA 480

GAACCACGAC AAAGGGGCAG CTCAGGTAAA CCTATATCAC CCAGAGGAGG AAAAAGTGGC 540

AAATCTAGAC GGGACTCAAC AGAGGGCAGT AAGTCTAGCT CCAAACGCCG TAGTCGGAGT 600

AAGTCTGCAG ACAAGCCGGC CAAGGAGTCT AAGCAGGACA AGGTGACCAA AAGCACCAAG 660

GACACAGGTG TAAAAGACAG AGGGCGTGGA AGGAGCAGGT CAAAAGACAG GAAGCGTTCA 720

CACAGCACTG ATAGGTCCAA GGAGAGAAGG AAGTCCAACT CTCCTTCCAG CTTCAGGGCA 780

GAGCAGAAAG TCGGCCGCAC TGATAAACGG TCCTCTCCGC AGCGGGATGA TAGACCCAAC 840

CAGGAAAGAG TGAGCCGACG GTCCAGATCG CCTGGACGGG AACGGCCAAG TCGCTCAGAC 900

GCTGACCGGG ACAAACGGCC AGCCAAGTCA CCATCCAAGG ACACTTCTTT AGGAAAGGAA 960

AACCGTTCCC CTCATAGACG AGGGGCTCAC AGCCCTGCAA GGAAACGCAG CGCTTCCCCT 1020

CGCCATAGAG ATGCCCGCTA CCCTTCGGCT AGTGCCTCAG AAAGGACATC AAAACAGAGC 1080

CACTCTCCTT CCAGAACTAG GTTCTCGCCC CAGAGACGCC GTAGCCGCTC ACCAGAGGTC 1140

AGGAGGCGAG ATGCTGAGAG GCAGGAGTCA CCACTGAGGA AGCGCTCTCG GGCAGATGTT 1200

GGACCAGGCA GAGACCGATC GCGCGATAAC AGTCCGAGAT CATCGTCTCG CCGCAGGATG 1260

AGTCGCTCGC CTCTAAGACG ACGGTCCCCA TCGCCACGCC GCCGCTCCCG CTCCTCCCCC 1320

CGCAGACGGA GCAGGTCTCC ACTGAGACGG AGGTCTGGGG AGAGAGACCG ATATGGTCGA 1380

CTCCGACAGT ATCGACGCTC AACGTCCCGC GATCGGGAAA GAAGGCGACG CGGCAGAGAT 1440

GAAGACAAGT TTAAGGGAAG TCTCTCAGAG GGCATGAAAG TCGATCAGGA GTCCTCAGAG 1500

GAAGAAGTTT TGGAGGATTT TGATGGTGAG GAGATAGATG AAGAAGCTCT CATTGAGCAG 1560

CGCCGCCAAC AGCGTATGGC CATCGTCCAG AAGTACAAAA TCGTGAACGA GGACACCAAT 1620

CAGACATCGG AGCCCAGCAG CCCCCAGAGC AGCACGCGTA GCCGTTCGCC CTCACCCGAT 1680

GACATCTTGG AGCGAGTAGC CGCAGACGTG AAGGAGTACG AGCGTGAGAA TCTCAACACC 1740

TTCGAGGCCA GCATCAAAGC CAAGCACAAC CTCATCGCCC AGGAGAAAGA CGGTAGATCT 1800

AACCCGAAGA AGCCTTCAGC TCCAGACATG TTTACCGAGT CAGATGACAT GTTTGCTGCA 1860

GACTTTGACA GTGCCAGGAT GAGAGCAGCC GGTGTAGGAA AGGACTTCAA GGAGAACCCC 1920

AACCTCAGGG ACAACTGGAC TGATGCTGAG GGTTACTACC GAGTGAACAT CGGGGAGACG 1980

CTGGACAAAC GTTACGACGT GTATGGCTAC ACTGGACAAG GTGTGTTCAG CAATGTGATC 2040

AGAGCCAGAG ACACTGCCCG AGCCGGCCAG GAGGTGGCAA TCAAGATCAT CCGAAACAAC 2100

GAGCTCATGC ACAAGACTGG TTTAAAAGAG CTGGAATTCC TCAAGAAGCT GAATGACGCC 2160

GATCCCGATG ACAAGTTCCA CTGCCTGCGC CTTTTCAGGC ACTTTTACCA CAAGCAGCAT 2220

CTTTGTTTGG TGTTTGAGCC TCTAAGCATG AATTTGCGAG AGGTGTTGAA GAAGTACGGT 2280

AAAGATGTTG GGCTTCACAT CAAAGCTGTG CGTTCCTACA GCCAGCAGCT CTTCTTGGCT 2340

CTCAAGCTGC TCAAACGATG CAACATTCTC CACGCCGACA TCAAGCCAGA TAATATCCTG 2400

GTGAACGAGT CAAAGACCAT CCTGAAGCTG TGTGACTTTG GTTCGGCATC ACATGTTGCT 2460

GACAATGACA TCACACCATA TCTGGTCAGC AGATTTTACA GGGCTCCAGA AATTATCATA 2520

GGAAAGCCGT ACGACTATGG CATCGACATG TGGTCCGTCG GCTGCACTCT GTACGAGCTT 2580

TACACGGGCA AAATCCTGCT TCCCGGATCT TCCAACAATC ACATGCTCAA GCTAGCTATG 2640

GACCTCAAGG GCAAGATGCC CAACAAGATG ATCCGTAAAG GATTGTTCAA AGACCAGCAC 2700

TTCGATCAGA ATTTGAACTT CTTGTACATT GAAGTAGACA AAGTGACTGA AAGGGAGAAG 2760

GTGACAGTGA TGAGCACCAT CAACCCCACC AAAGACCTGC TGGCAGACAT GATAGGAGGC 2820

CAGCGGCTGC CCGAGGACCA GAGGAAGAAG GTAATGCAGC TGAAGGACCT GCTGGATGGA 2880

ACGCTGATGC TGGACCCTGC CAAGCGCATC AGTATCAACC AGGCTCTGCA GCACCCCTTT 2940

ATCCAGGAGA AGATCTGA 2958

Domain Profile

S: 1     yevlevigkGsfgqVvkaldk.ktkeivaikiiknkkrfarqaqeEveiLeklnkkdkee  59

         y+v+ ++g+G+f++V++a+d+ ++ ++vaikii+n++ +++++ +E+e+L+kln++d+++

Q: 665   YDVYGYTGQGVFSNVIRARDTaRAGQEVAIKIIRNNELMHKTGLKELEFLKKLNDADPDD  724

         99******************97899***********************************

S: 60    kynvvrllelfvfrnhlclvfellsqnLyellkknkfs.glslklvrklaqqilkaLklL  118

         k++++rl+++f++++hlclvfe ls+nL+e+lkk++++ gl++k+vr+++qq++ aLklL

Q: 725   KFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDvGLHIKAVRSYSQQLFLALKLL  784

         ************************************999*********************

S: 119   kelkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglk  178

         k+++i+HaD+KP+Nil++e+k+  +k++DFGs+s+v++++i++y++srfYraPEii+g++

Q: 785   KRCNILHADIKPDNILVNESKTI-LKLCDFGSASHVADNDITPYLVSRFYRAPEIIIGKP  843

         *********************99.************************************

S: 179   ydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftk  238

         yd+ iDmWS+Gc+l+El+tGk+L+pG++++++l+l ++++g++p+k+++k+  ++++f++

Q: 844   YDYGIDMWSVGCTLYELYTGKILLPGSSNNHMLKLAMDLKGKMPNKMIRKGLFKDQHFDQ  903

         ************************************************************

S: 239   keapkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedkl.fkdllkrmle  297

         + ++ yi ++k+++r+k++v+++++ +k+  a++   ++ +++++++ + +kdll+  l+

Q: 904   NLNFLYIEVDKVTEREKVTVMSTINPTKDLLADMIGGQRLPEDQRKKVMqLKDLLDGTLM  963

         *********************************************99999**********

S: 298   ldpakRitpkealkhpfv  315

         ldpakRi++++al+hpf+

Q: 964   LDPAKRISINQALQHPFI  981

         *****************7

Domain Sequence
(FASTA)

YDVYGYTGQG VFSNVIRARD TARAGQEVAI KIIRNNELMH KTGLKELEFL KKLNDADPDD 60

KFHCLRLFRH FYHKQHLCLV FEPLSMNLRE VLKKYGKDVG LHIKAVRSYS QQLFLALKLL 120

KRCNILHADI KPDNILVNES KTILKLCDFG SASHVADNDI TPYLVSRFYR APEIIIGKPY 180

DYGIDMWSVG CTLYELYTGK ILLPGSSNNH MLKLAMDLKG KMPNKMIRKG LFKDQHFDQN 240

LNFLYIEVDK VTEREKVTVM STINPTKDLL ADMIGGQRLP EDQRKKVMQL KDLLDGTLML 300

DPAKRISINQ ALQHPFI 317

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>