EKS-ORN-00616

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00616

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	369.5	1.2E-110	33	287	255

Status

Unreviewed

Ensembl Protein

ENSONIP00000009210

UniProt Accession

I3JK16;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000007301	ENSONIP00000009210	ENSONIT00000009215
ENSONIG00000007301	ENSONIP00000009211	ENSONIT00000009216

Organism

Oreochromis niloticus

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

SSAIIMPTSR PGSEPVEFWV DGSRRDGTVE EFYTLSSELG RGATSIVYRC EEKQTQKPYA 60

VKVLKKTIDK KIVRTEIGVL LRLSHPNIIQ LKEIFETDTD IALVLELVTG GELFDRIVER 120

GYYSERDAAH VIKQILEAVA YLHENGVVHR DLKPENLLYA DLSLDAPLKI ADFGLSKIID 180

DQVTMKTVCG TPGYCAPEIL RGNAYGPEVD MWSVGVILYI LLCGFEPFFD PRGDQYMYSR 240

ILNCDYEFVS PWWDEVSLNA KDLVSKLIVL DPHKRLSVRE ALQHPWVLGK AARFSHMDTT 300

QRKLQEFNAR RKLKAAMKAV VATSRMHEGS RRRTDSCDIP GSGASRQSSM QQDPPPESAC 360

STQKDKE 367

Nucleotide Sequence
(FASTA)

AGTTCTGCTA TCATCATGCC GACGTCCCGG CCTGGTTCGG AGCCAGTGGA GTTCTGGGTG 60

GACGGATCAA GGCGGGACGG GACGGTGGAG GAATTCTACA CCCTGAGCTC GGAGCTGGGC 120

AGAGGAGCGA CTTCCATTGT GTATCGCTGT GAGGAGAAAC AGACCCAGAA ACCCTACGCC 180

GTCAAAGTCC TCAAGAAAAC GATTGACAAG AAAATTGTTC GCACCGAAAT CGGCGTTCTG 240

CTGCGTCTTT CTCACCCAAA CATTATCCAG CTGAAGGAGA TCTTTGAGAC AGACACAGAC 300

ATTGCTCTGG TGCTGGAGTT GGTGACTGGA GGAGAGCTCT TTGACCGGAT TGTGGAACGT 360

GGTTACTACA GTGAGAGAGA TGCCGCTCAT GTCATCAAAC AGATACTGGA GGCTGTGGCG 420

TATTTACATG AGAACGGTGT TGTGCATCGT GACCTTAAAC CAGAGAATCT GCTGTACGCC 480

GACCTGTCTC TGGATGCTCC ACTGAAGATA GCTGACTTTG GTCTTTCGAA AATCATAGAT 540

GACCAGGTGA CCATGAAGAC AGTCTGCGGT ACTCCAGGGT ATTGCGCTCC AGAGATCCTG 600

CGGGGAAATG CCTACGGCCC TGAGGTGGAC ATGTGGTCGG TGGGCGTGAT CCTCTACATC 660

CTACTCTGTG GGTTTGAGCC CTTCTTCGAC CCAAGAGGGG ATCAGTACAT GTATAGTCGT 720

ATCCTCAACT GTGACTATGA GTTTGTTTCT CCGTGGTGGG ATGAGGTCTC TCTCAATGCT 780

AAGGATCTGG TCAGTAAGCT GATTGTCCTC GACCCTCACA AGCGCCTCAG TGTCCGGGAG 840

GCCCTGCAGC ACCCCTGGGT GTTGGGTAAA GCTGCCCGGT TCTCTCATAT GGATACCACC 900

CAGAGGAAAC TACAGGAGTT CAACGCTCGA CGCAAACTTA AGGCGGCCAT GAAAGCTGTC 960

GTGGCCACAA GTCGGATGCA TGAAGGTTCG CGGCGTCGCA CAGACAGCTG TGACATTCCA 1020

GGTTCAGGGG CTTCCAGGCA GAGCAGCATG CAGCAGGACC CGCCTCCTGA GTCTGCATGC 1080

TCCACCCAAA AAGACAAAGA G 1101

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y+l+++lG+Ga+s v++++ek+tqk++a+kv+kk+    +++ v++ei vl +l+hpni+

Q: 33    YTLSSELGRGATSIVYRCEEKQTQKPYAVKVLKKTI---DKKIVRTEIGVLLRLSHPNII  89

         8899****************************9998...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e+++ + lvlelvtGGelfdrive+g+y+e+da++vikq+leav+ylhe+g+vh

Q: 90    QLKEIFETDTDIALVLELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVH  149

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++ + d+++kiadfGlsk+ +++  +kt+cGt+gy+ape+l+ ++y+ +v

Q: 150   RDLKPENLLYADLSLDAPLKIADFGLSKIIDDQvTMKTVCGTPGYCAPEILRGNAYGPEV  209

         ****************************88888689************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+Gvi+yillcG++pf+d + +++  ++il+++yef sP+Wde+s +akd++ kl+

Q: 210   DMWSVGVILYILLCGFEPFFDPRGDQYmYSRILNCDYEFVSPWWDEVSLNAKDLVSKLIV  269

         *********************998886379******************************

S: 239   ldpekrytieqaledpWi  256

         ldp+kr+ +++al++pW+

Q: 270   LDPHKRLSVREALQHPWV  287

         *****************7

Domain Sequence
(FASTA)

YTLSSELGRG ATSIVYRCEE KQTQKPYAVK VLKKTIDKKI VRTEIGVLLR LSHPNIIQLK 60

EIFETDTDIA LVLELVTGGE LFDRIVERGY YSERDAAHVI KQILEAVAYL HENGVVHRDL 120

KPENLLYADL SLDAPLKIAD FGLSKIIDDQ VTMKTVCGTP GYCAPEILRG NAYGPEVDMW 180

SVGVILYILL CGFEPFFDPR GDQYMYSRIL NCDYEFVSPW WDEVSLNAKD LVSKLIVLDP 240

HKRLSVREAL QHPWV 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013