EKS-ORN-00076

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00076

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	417.1	4.1E-125	4	287	284

Status

Unreviewed

Ensembl Protein

ENSONIP00000011521

UniProt Accession

I3JRM7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK1

Gene Synonyms/Alias

CDK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000009163	ENSONIP00000011521	ENSONIT00000011530

Organism

Oreochromis niloticus

Functional Description

Protein Length

303

Protein Sequence
(FASTA)

MEDYLKIEKI GEGTYGVVYK GKHKATGQIV AMKKIRLESE EEGVPSTAVR EVSLLQELKH 60

PNVVRLLDVL MQESRLYLIF EFLSMDLKKY LDSIPSGQYM DSMLVKSYLY QILEGIYFCH 120

CRRVLHRDLK PQNLLIDNKG VIKLADFGLA RAFGVPVRVY THEVVTLWYR APEVLLGSPR 180

YSTPVDVWST GTIFAELATK KPLFHGDSEI DQLFRIFRTL GTPNNDVWPD VESLPDYKNT 240

FPKWKAGNLS SMVKNLDKNG LDLLAKMLTY NPPKRISARE AMTHPYFDDL DKSTLPAANI 300

NKI 303

Nucleotide Sequence
(FASTA)

ATGGAAGACT ACCTGAAAAT AGAGAAAATC GGAGAAGGTA CATATGGGGT TGTGTATAAA 60

GGTAAGCACA AGGCAACGGG GCAAATTGTG GCTATGAAGA AGATCCGTCT AGAGAGCGAG 120

GAGGAGGGCG TTCCCAGCAC AGCTGTCAGA GAGGTTTCTC TGCTCCAGGA GCTGAAACAT 180

CCCAATGTTG TACGACTCCT AGATGTCCTA ATGCAAGAAT CTCGTCTCTA CCTCATCTTC 240

GAGTTCCTGT CCATGGACCT GAAGAAATAC TTGGACTCCA TCCCCTCGGG CCAGTACATG 300

GACTCTATGT TGGTCAAGAG CTACCTTTAC CAGATATTGG AGGGCATCTA CTTCTGTCAC 360

TGTCGCCGAG TGCTCCATCG TGACCTGAAA CCACAGAATC TGCTGATTGA CAACAAGGGC 420

GTTATCAAAC TGGCAGACTT TGGTTTGGCT AGAGCCTTTG GTGTTCCTGT CAGGGTCTAC 480

ACCCATGAGG TTGTCACTCT TTGGTACCGG GCCCCAGAGG TCCTGCTAGG GTCACCCCGA 540

TATTCCACCC CCGTTGATGT TTGGAGCACT GGGACAATCT TTGCTGAACT TGCTACTAAG 600

AAGCCTCTGT TTCATGGAGA CTCTGAGATA GACCAGCTCT TCAGGATTTT CAGGACGCTG 660

GGAACCCCAA ACAATGATGT GTGGCCTGAT GTTGAGAGTC TGCCAGACTA CAAAAACACT 720

TTTCCCAAAT GGAAAGCTGG CAACCTGTCA TCCATGGTGA AAAACCTGGA TAAGAATGGC 780

CTGGACCTCC TGGCGAAAAT GCTGACCTAC AATCCCCCCA AACGGATCTC TGCCCGTGAG 840

GCCATGACGC ACCCTTACTT TGACGACTTG GACAAATCCA CCCTGCCAGC TGCCAACATC 900

AACAAAATCT AA 912

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y k+ekigeGtyg+vyk+k+k tg++vA+Kkirle+e+egvp+ta+rE+sll+elkh+n+

Q: 4     YLKIEKIGEGTYGVVYKGKHKATGQIVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV  63

         779*********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkk.klsleevkslllqlleglaylHsn  119

         v+Ll+v++ ++++lyL+fefl++dLkk+l++ ++  ++++  vks+l+q+leg+ ++H +

Q: 64    VRLLDVLM-QESRLYLIFEFLSMDLKKYLDSIPSGqYMDSMLVKSYLYQILEGIYFCHCR  122

         ********.99********************9876589999*******************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         ++lHRDlKpqNlLi+++g++klaDfGlaraf++p++ yt+evvTlwYraPe+Llg+ +Ys

Q: 123   RVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYS  182

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfp  239

         t vD+Ws g i+ael+t+kplf+g+seidql+rif++lgtp+++vwp+v++lp+yk++fp

Q: 183   TPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFP  242

         ************************************************************

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k+ +l+++vk+l++++ldll k+l+++p kRisa+ea++h+yf

Q: 243   KWKAGNLSSMVKNLDKNGLDLLAKMLTYNPPKRISAREAMTHPYF  287

         ********************************************9

Domain Sequence
(FASTA)

YLKIEKIGEG TYGVVYKGKH KATGQIVAMK KIRLESEEEG VPSTAVREVS LLQELKHPNV 60

VRLLDVLMQE SRLYLIFEFL SMDLKKYLDS IPSGQYMDSM LVKSYLYQIL EGIYFCHCRR 120

VLHRDLKPQN LLIDNKGVIK LADFGLARAF GVPVRVYTHE VVTLWYRAPE VLLGSPRYST 180

PVDVWSTGTI FAELATKKPL FHGDSEIDQL FRIFRTLGTP NNDVWPDVES LPDYKNTFPK 240

WKAGNLSSMV KNLDKNGLDL LAKMLTYNPP KRISAREAMT HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013