EPS-ORN-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORN-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	213.9	4.4E-63	84	366	283

Status

Unreviewed

Ensembl Protein

ENSONIP00000013159

UniProt Accession

I3JWB4;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D (1 of 2)

Gene Synonyms/Alias

PPM1D (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000010468	ENSONIP00000013159	ENSONIT00000013169

Organism

Oreochromis niloticus

Functional Description

Protein Length

530

Protein Sequence
(FASTA)

MENALLMRVS VFTDQGGRKY MEDVTEVIVE PEPGENEPTT DKTVESPQVL NASSELVQTE 60

DGGISVETPS PGDLSTPQVQ PNTPTCSRRS VAFFAVFDGH GGREAAQFAR DYLWEFMKKQ 120

RGFWSDCDRE VCSAIRKGFV ACHHAMWKKL PEWPKTLTGL PSTSGTTASV VVLRGNRMYV 180

AHVGDSAVVL GVQDDPSVPF IRAVEVTQDH KPELPKERER IEGLGGRNSV IKKSGVNRVV 240

WKRPRLSHNG PVRRSTVIDQ IPFLAVARAL AGDLWSYDFY SGEFVVSPEP DTSVVVLDPK 300

KHRYIILGSD GLWNMVPPQE AISMCQNNDE EMAPCGVSSA RQLVSHALLR WRQRMLRADN 360

TSAIVIALQE PGTCQDTLHH EEVLLDLAKV SQCPPTSISR ADTPLVQRLP EEDSPAATSL 420

ERRDGLSGSN SFYHMDLSDP FALTPLCSNS SPELPALSSA TDRTVGSRTP TRKRTIDVSS 480

SPSGLLAKKA RRRTAERPPL VQHNAEKKQK DSNNVSSILQ QHKSTTVCVC 530

Nucleotide Sequence
(FASTA)

ATGGAAAACG CATTACTGAT GCGAGTGAGT GTTTTTACCG ATCAAGGAGG CAGGAAATAC 60

ATGGAAGATG TGACCGAGGT CATAGTAGAG CCTGAGCCGG GAGAAAATGA GCCGACGACG 120

GATAAAACCG TGGAGTCCCC GCAGGTTTTA AACGCATCCA GTGAACTCGT ACAAACAGAA 180

GACGGGGGTA TATCGGTAGA AACGCCGTCA CCAGGAGATC TGAGCACGCC GCAAGTTCAG 240

CCGAACACCC CGACTTGTTC CCGCCGTTCC GTAGCATTCT TCGCCGTTTT TGATGGTCAC 300

GGGGGTCGCG AGGCTGCGCA GTTTGCGCGA GACTATCTTT GGGAGTTCAT GAAGAAACAG 360

CGGGGGTTCT GGTCAGACTG TGACCGGGAG GTCTGCTCTG CCATACGCAA AGGATTTGTA 420

GCATGCCACC ATGCTATGTG GAAGAAACTG CCTGAATGGC CAAAGACACT TACAGGCCTT 480

CCTAGTACAT CAGGTACCAC AGCCAGTGTA GTGGTCCTCC GAGGAAACCG CATGTATGTG 540

GCCCATGTTG GGGACTCTGC AGTGGTTCTA GGTGTCCAGG ATGACCCTTC AGTCCCATTC 600

ATCAGAGCCG TGGAAGTCAC GCAGGACCAT AAACCAGAAC TTCCCAAAGA GAGGGAGCGT 660

ATTGAAGGTC TAGGAGGAAG GAACAGCGTG ATCAAGAAGT CTGGGGTGAA TCGGGTGGTG 720

TGGAAGAGGC CAAGACTCAG CCACAATGGT CCAGTCCGTC GTAGTACTGT GATTGACCAG 780

ATACCATTCT TGGCAGTAGC TCGAGCTTTA GCAGGCGATC TATGGAGTTA TGACTTCTAC 840

AGTGGAGAGT TTGTGGTTTC TCCAGAGCCT GACACTAGCG TGGTGGTTCT TGACCCTAAA 900

AAACATCGCT ACATCATCCT GGGCAGCGAT GGTCTGTGGA ATATGGTTCC TCCTCAAGAG 960

GCCATCTCCA TGTGTCAGAA TAATGACGAG GAAATGGCAC CATGTGGGGT CTCGAGTGCC 1020

AGGCAGCTGG TCAGTCATGC TTTGCTGCGG TGGCGCCAGC GGATGTTGCG TGCAGACAAT 1080

ACAAGCGCCA TAGTAATTGC CCTACAAGAG CCTGGGACCT GCCAGGATAC CCTGCACCAT 1140

GAGGAAGTGC TGCTCGACCT AGCCAAGGTG TCTCAGTGCC CCCCCACCTC CATATCCCGC 1200

GCAGACACTC CTCTTGTTCA GCGACTTCCA GAGGAGGACT CTCCTGCGGC CACATCGTTG 1260

GAGCGACGAG ATGGGCTATC GGGAAGCAAC AGCTTTTATC ACATGGATCT ATCTGACCCC 1320

TTTGCTCTGA CTCCGCTGTG TTCAAACAGC AGCCCTGAGC TGCCCGCCCT GTCCAGTGCA 1380

ACGGACAGGA CAGTTGGCAG CAGGACACCC ACCAGAAAAA GAACTATTGA CGTGTCATCA 1440

AGCCCATCAG GCCTGCTGGC AAAGAAAGCC CGGCGCAGGA CTGCCGAAAG ACCGCCACTG 1500

GTGCAACACA ACGCAGAGAA GAAACAGAAA GACTCCAATA ATGTGTCCTC CATTCTCCAG 1560

CAGCATAAAA GTACCACAGT GTGTGTGTGC TAA 1593

Domain Profile

S: 28    spekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkvkkalakaFlstd  87

         ++++++ +aff+v+DGhgg+e+a+f+++ l+e+++++  + ++ +r+v++a++k+F +++

Q: 84    PTCSRRSVAFFAVFDGHGGREAAQFARDYLWEFMKKQRGFWSDCDREVCSAIRKGFVACH  143

         5567777*****************************************************

S: 88    eel.....kvleeksldidksGstavvalikdsklyvanvGdSravLcrngk.......a  135

          ++     +++++ +  +++sG+ta+v++++++ +yva+vGdS +vL+ +++       a

Q: 144   HAMwkklpEWPKTLTGLPSTSGTTASVVVLRGNRMYVAHVGDSAVVLGVQDDpsvpfirA  203

         *************************************************88768999999

S: 136   velssdHkpsredEleRieeag..gsvilkdga.Rv.....................lGv  171

         ve+++dHkp+ ++E+eRie  g   svi+k+g+ Rv                     +++

Q: 204   VEVTQDHKPELPKERERIEGLGgrNSVIKKSGVnRVvwkrprlshngpvrrstvidqIPF  263

         **********************6668**********************************

S: 172   LavsRal.Gdlylk......pyvtpePevtshrltsede.fliLasDGlwdvvsneeavs  223

         Lav+Ral Gdl+++      ++v+peP+++++ l+++++ ++iL+sDGlw++v+++ea+s

Q: 264   LAVARALaGDLWSYdfysgeFVVSPEPDTSVVVLDPKKHrYIILGSDGLWNMVPPQEAIS  323

         ******98999999**********************************************

S: 224   lvrdvlekkeae.qeaakkLvklalargsk.....dnvsaivv  260

         ++++  e+ +++  + a +Lv +al r+++     dn+saiv+

Q: 324   MCQNNDEEMAPCgVSSARQLVSHALLRWRQrmlraDNTSAIVI  366

         ****9995555515788899999999999888888******97

Domain Sequence
(FASTA)

PTCSRRSVAF FAVFDGHGGR EAAQFARDYL WEFMKKQRGF WSDCDREVCS AIRKGFVACH 60

HAMWKKLPEW PKTLTGLPST SGTTASVVVL RGNRMYVAHV GDSAVVLGVQ DDPSVPFIRA 120

VEVTQDHKPE LPKERERIEG LGGRNSVIKK SGVNRVVWKR PRLSHNGPVR RSTVIDQIPF 180

LAVARALAGD LWSYDFYSGE FVVSPEPDTS VVVLDPKKHR YIILGSDGLW NMVPPQEAIS 240

MCQNNDEEMA PCGVSSARQL VSHALLRWRQ RMLRADNTSA IVI 283

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>