EKS-ORN-00058

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00058

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	370.8	4.4E-111	37	303	267

Status

Unreviewed

Ensembl Protein

ENSONIP00000013928

UniProt Accession

I3JYI3;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK1

Gene Synonyms/Alias

VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000011064	ENSONIP00000013928	ENSONIT00000013938

Organism

Oreochromis niloticus

Functional Description

Protein Length

427

Protein Sequence
(FASTA)

MPPKAKAAGR GRAPAKRKLA EEFPPGEVLK DTMKKEWKLG APIGQGGFGV IYLAEENSAK 60

PVGADARYVI KVEPIDNGPL FCELAFYMRA AKPDLIQSWM KSKKLKNLGV PRYWGSGRHE 120

RGGQSYRFMV IDRLGTDLQK KFEECGRRFP RKLVLQLGLR LLDTLEYIHE HEYVHADVKA 180

SNLMLSHSDP NQVYLVDYGL AYRYAPEGRP KEYKEDPKKC HDGTIEFTSI DCHKGASVSR 240

RSDLEILSYC MVQWLCGRLP WEDKLQDPLY VRDSKIRSQE NITEFMAKCF SSQDKPDEIQ 300

RFMEEVKSLG YTAKPPYDKL RSILQAGLKT IGAKEDGKLE FTSVNGAASP PTKKMSKRKM 360

AADEAEVSEV DSNPVKKKRV TKKKEVNRPK KSPKKTPKSR KVPSSDPKSR LVEMGTQTSL 420

GLAQKST 427

Nucleotide Sequence
(FASTA)

ATGCCCCCTA AAGCCAAGGC GGCAGGCAGA GGCAGAGCCC CTGCCAAGAG GAAACTGGCA 60

GAGGAGTTTC CTCCTGGAGA AGTGCTGAAG GACACCATGA AGAAGGAATG GAAGCTGGGG 120

GCTCCGATCG GTCAAGGGGG CTTTGGTGTC ATATACTTGG CGGAGGAAAA TTCTGCAAAG 180

CCTGTGGGTG CTGATGCTCG CTATGTCATC AAAGTGGAGC CTATTGACAA TGGACCGCTT 240

TTCTGCGAGC TCGCATTTTA CATGAGAGCT GCCAAGCCGG ATCTCATTCA GAGTTGGATG 300

AAGTCCAAGA AGCTGAAAAA CCTGGGCGTG CCCCGGTACT GGGGCTCAGG TCGACATGAG 360

AGAGGGGGTC AAAGTTACAG GTTCATGGTC ATCGACAGAC TTGGCACAGA CCTGCAGAAG 420

AAATTTGAGG AATGTGGAAG GAGATTTCCC AGAAAGCTGG TCCTGCAGCT CGGCCTTCGA 480

CTGCTGGATA CTCTGGAGTA CATCCACGAG CACGAGTACG TGCACGCTGA TGTGAAGGCG 540

TCTAACCTCA TGTTGAGTCA CAGCGATCCT AACCAGGTTT ACTTAGTAGA TTATGGACTG 600

GCCTATAGGT ACGCACCTGA AGGTCGGCCC AAGGAGTACA AGGAAGACCC CAAGAAATGT 660

CACGATGGTA CCATCGAGTT CACAAGCATC GACTGCCACA AAGGAGCATC CGTGTCCAGG 720

CGCAGCGACC TGGAGATCCT GTCCTACTGC ATGGTTCAGT GGCTGTGTGG TCGGCTCCCC 780

TGGGAGGACA AGTTGCAGGA CCCGCTGTAC GTCAGAGACT CCAAGATCCG GAGTCAAGAA 840

AACATAACAG AGTTCATGGC CAAGTGTTTC TCCTCTCAAG ACAAACCAGA TGAGATACAG 900

CGGTTCATGG AGGAGGTGAA ATCTCTGGGC TACACAGCCA AACCACCCTA CGACAAGCTG 960

CGCTCTATCC TACAGGCTGG ACTGAAGACC ATCGGTGCTA AAGAGGACGG CAAGCTGGAG 1020

TTCACCTCTG TCAATGGAGC AGCGTCGCCT CCCACCAAGA AGATGAGCAA AAGAAAGATG 1080

GCAGCAGATG AAGCGGAGGT AAGCGAGGTG GATTCAAATC CCGTCAAGAA AAAGAGAGTC 1140

ACAAAGAAGA AAGAGGTAAA CAGACCGAAG AAAAGTCCCA AAAAGACTCC AAAATCCAGG 1200

AAGGTGCCCA GCAGTGACCC CAAATCCAGA CTTGTGGAAA TGGGAACCCA GACATCACTT 1260

GGACTCGCCC AGAAATCCAC CTGA 1284

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wklg +ig+ggfG+iyla  +++k ++ da++v+kvep +nGpLf el fy+raak++ i

Q: 37    WKLGAPIGQGGFGVIYLAeeNSAKPVGADARYVIKVEPIDNGPLFCELAFYMRAAKPDLI  96

         9*****************9999999***********************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         ++w+k kklk lg+P +++sG he +g++yRf+v++rlg+dLqk  e+ g+r+ +k vlq

Q: 97    QSWMKSKKLKNLGVPRYWGSGRHERGGQSYRFMVIDRLGTDLQKKFEECGRRFPRKLVLQ  156

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++rlld ley+He+eYvH+d+kA+nl+l++ +++qvyLvdyGlayry+peg+ keyked

Q: 157   LGLRLLDTLEYIHEHEYVHADVKASNLMLSHSDPNQVYLVDYGLAYRYAPEGRPKEYKED  216

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         ++++HdGt+efts+D HkG++ srRsDleiL+Yc+++Wl+g LPWe++l+dp +v+++k

Q: 217   PKKCHDGTIEFTSIDCHKGASVSRRSDLEILSYCMVQWLCGRLPWEDKLQDPLYVRDSKI  276

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         +  +++ e++ k++ ++ ++ e+++++

Q: 277   RSQENITEFMAKCFSSQDKPDEIQRFM  303

         ************************997

Domain Sequence
(FASTA)

WKLGAPIGQG GFGVIYLAEE NSAKPVGADA RYVIKVEPID NGPLFCELAF YMRAAKPDLI 60

QSWMKSKKLK NLGVPRYWGS GRHERGGQSY RFMVIDRLGT DLQKKFEECG RRFPRKLVLQ 120

LGLRLLDTLE YIHEHEYVHA DVKASNLMLS HSDPNQVYLV DYGLAYRYAP EGRPKEYKED 180

PKKCHDGTIE FTSIDCHKGA SVSRRSDLEI LSYCMVQWLC GRLPWEDKLQ DPLYVRDSKI 240

RSQENITEFM AKCFSSQDKP DEIQRFM 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>