EKS-ORN-00319

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00319

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.2	3.3E-101	26	278	253

Status

Unreviewed

Ensembl Protein

ENSONIP00000014173

UniProt Accession

I3JZ78;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000011261	ENSONIP00000014173	ENSONIT00000014183

Organism

Oreochromis niloticus

Functional Description

Protein Length

580

Protein Sequence
(FASTA)

TPQQGHCGKM ATEKAKHEGR VKIGHYILGD TLGVGTFGKV KVGQHELTKH QVAVKILNRQ 60

KIRSLDVVGK IRREIQNLKL FRHPHIIKLY QVISTPTDIF MVMEYVSGGE LFDYICKNGK 120

LDEKESRRLF QQIISAVDYC HRHMVVHRDL KPENVLLDAQ MNAKIADFGL SNMMSDGEFL 180

RTSCGSPNYA APEVISGRLY AGPEVDIWSS GVILYALLCG TLPFDDDHVP TLFKKICDGI 240

FFTPQYLNPA VISLLKHMLQ VDPMKRATIK EIREDEWFKK DLPKYLFPED PSYSNNMIDD 300

EALKEVCEKF ECTEEEVLAC IYSRNHQDPL AVAYHLIIDN RRIMSEAKDF YLASSPPDSF 360

LDDQHLTSSG AAIVKPHPER VPFLVAETPP RSIRHTLDEL NPQKSKHQGV RRAKWHLGIR 420

SQSRPNDIMT EVCRAMKQLD YEWKVVNPYY LRVRRKNPVT GMLAKMSLQL YTVDSRTYLL 480

DFRSIDDDML ETKSGSATPL RSGSVGNYRT AIKNDVDGAE LPGTPSTVHP TKTGEGSLTS 540

SLTSSIDSTG GGDNATVPRP GSHTIEFFEM CANLIKLLAR 580

Nucleotide Sequence
(FASTA)

ACCCCGCAGC AAGGCCATTG CGGGAAGATG GCGACGGAAA AAGCGAAGCA TGAAGGAAGA 60

GTGAAAATTG GACATTACAT TCTTGGAGAC ACTCTCGGAG TGGGGACGTT TGGGAAGGTT 120

AAAGTGGGCC AACATGAGCT GACCAAGCAT CAAGTGGCAG TGAAGATCTT GAACAGACAG 180

AAGATCCGCA GTTTGGACGT GGTGGGAAAG ATTCGCCGGG AGATCCAGAA CCTCAAGCTT 240

TTCAGGCACC CTCACATAAT TAAACTGTAT CAGGTTATCA GCACCCCTAC AGATATCTTC 300

ATGGTGATGG AGTATGTCTC AGGGGGAGAG CTCTTTGACT ACATCTGCAA AAATGGAAAG 360

TTGGATGAAA AGGAGAGTCG ACGACTGTTC CAGCAGATCA TTTCAGCAGT AGACTACTGC 420

CACAGACACA TGGTGGTACA TCGAGACCTT AAGCCAGAAA ATGTGCTGCT TGATGCGCAA 480

ATGAATGCTA AGATTGCAGA CTTTGGTTTG TCAAACATGA TGTCAGATGG AGAGTTCCTT 540

AGAACAAGCT GTGGTTCTCC AAACTATGCT GCTCCTGAGG TCATCTCAGG AAGGTTATAT 600

GCTGGACCAG AGGTGGATAT TTGGAGTAGT GGGGTGATTC TCTACGCCTT GTTGTGTGGA 660

ACACTTCCCT TTGATGATGA TCATGTGCCA ACACTTTTTA AGAAGATCTG TGATGGGATC 720

TTCTTCACCC CACAGTATCT GAACCCTGCA GTAATAAGCT TACTGAAACA CATGTTGCAG 780

GTGGACCCGA TGAAAAGAGC CACAATCAAA GAGATCCGAG AGGACGAGTG GTTCAAAAAA 840

GATCTGCCGA AGTACTTGTT CCCTGAGGAC CCCTCCTACA GCAACAACAT GATCGACGAC 900

GAGGCCCTGA AGGAAGTTTG TGAGAAGTTT GAGTGCACAG AGGAGGAGGT CCTTGCCTGC 960

ATATACAGTC GCAACCATCA GGATCCATTG GCTGTCGCCT ACCATCTCAT CATTGACAAT 1020

CGTCGCATCA TGAGCGAAGC CAAGGATTTC TACTTGGCAT CTAGCCCTCC TGACTCTTTT 1080

CTAGATGACC AACACCTGAC TTCATCAGGT GCAGCGATAG TCAAGCCTCA CCCTGAGCGT 1140

GTACCTTTTC TCGTGGCGGA GACTCCTCCC AGGAGTATCC GTCACACACT GGATGAACTG 1200

AACCCTCAGA AGTCCAAGCA CCAGGGTGTT AGGAGAGCCA AGTGGCACCT GGGTATACGC 1260

AGTCAAAGTA GACCAAATGA TATCATGACG GAGGTGTGCC GTGCAATGAA ACAGCTGGAT 1320

TATGAGTGGA AGGTTGTGAA TCCATATTAT CTGCGTGTGA GAAGGAAGAA TCCTGTTACT 1380

GGGATGCTTG CCAAGATGAG CCTTCAACTG TACACAGTGG ACAGCAGAAC CTACCTCCTT 1440

GACTTCCGTA GCATAGACGA TGATATGTTG GAGACAAAAT CTGGAAGTGC TACCCCTCTG 1500

CGCTCTGGCT CTGTGGGCAA CTACCGGACC GCTATTAAGA ACGATGTAGA TGGAGCAGAG 1560

CTTCCAGGTA CACCTAGTAC TGTGCACCCC ACCAAGACTG GAGAAGGCTC TTTGACGTCA 1620

TCGTTGACCT CATCCATCGA TTCCACAGGA GGCGGGGACA ATGCAACTGT CCCTCGACCA 1680

GGAAGCCACA CCATCGAGTT CTTTGAGATG TGTGCAAATC TTATTAAACT ACTTGCACGA 1740

TAG 1743

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ +h++tk++vavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 26    YILGDTLGVGTFGKVKVGQHELTKHQVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  85

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++sav+Y+h++ +

Q: 86    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISAVDYCHRHMV  145

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 146   VHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  205

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l++ ++sLl+++L+vdp k

Q: 206   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPAVISLLKHMLQVDPMK  265

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati+ei+++ew+

Q: 266   RATIKEIREDEWF  278

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGQH ELTKHQVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDAQMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFFTPQ YLNPAVISLL KHMLQVDPMK 240

RATIKEIRED EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013