EKS-ORN-00267

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00267

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	461.7	8.6E-139	4	289	286

Status

Unreviewed

Ensembl Protein

ENSONIP00000014679

UniProt Accession

I3K0N4;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000011659	ENSONIP00000014679	ENSONIT00000014691

Organism

Oreochromis niloticus

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

MERYESLGPV GEGSYGTVLK CRHRDTGRLV AIKKFMDSDD DKTVKKIAHR EIKLLRQLRH 60

DNLVNLLEVW KRRRRWYLVF EFVDRTLLDD LQQNPSGLEM NTCRQYLYQI LRAASFCHQQ 120

NIIHRDIKPE NILISQEGVV KLCDFGFART VASTSEGSLL TDYVATRWYR APELLVGDIK 180

YGKPVDVWAL GCVLLEMLTG QPLFPGDSDL DQIYQIIRCF GNLTSHHQEL FYRNPVFSGV 240

TLPECSDRVT LQQRFPTITP ISLDLAQECL EIDPERRAQC SELLEHPLFT QDSFHIRFLD 300

ELNSKIQKDH RENSTFPKIT KNPRKNERDE KNCRGKDKKQ PEDMDEKVNK EKMEKVKG 358

Nucleotide Sequence
(FASTA)

ATGGAGCGTT ATGAATCTCT GGGTCCAGTT GGGGAGGGCA GTTACGGCAC GGTGCTTAAG 60

TGCCGTCATC GTGATACTGG TCGCCTTGTC GCCATCAAGA AATTCATGGA CTCTGATGAT 120

GACAAGACGG TGAAGAAGAT CGCCCACAGG GAGATCAAGC TACTCAGGCA ACTGCGACAC 180

GACAACCTTG TGAACCTCCT AGAAGTGTGG AAGCGCCGCC GCCGCTGGTA TCTGGTATTT 240

GAGTTTGTGG ACCGGACACT TCTTGATGAT CTGCAGCAAA ACCCAAGCGG GCTGGAGATG 300

AACACATGCC GACAGTACCT GTACCAGATC CTAAGGGCTG CGTCCTTCTG CCATCAGCAA 360

AATATCATCC ACCGTGACAT CAAACCAGAG AACATCCTCA TCTCTCAGGA GGGCGTGGTT 420

AAGCTGTGTG ATTTTGGCTT TGCCCGCACC GTTGCATCGA CCAGTGAGGG CAGCCTCCTC 480

ACTGACTATG TGGCCACTCG ATGGTACAGA GCCCCCGAAC TGCTGGTGGG AGACATTAAG 540

TATGGCAAAC CTGTAGATGT GTGGGCTTTG GGGTGTGTAT TATTAGAGAT GTTAACAGGT 600

CAGCCTCTGT TTCCTGGAGA CTCAGACCTT GACCAAATAT ATCAGATCAT CCGGTGCTTT 660

GGTAACCTCA CAAGTCATCA CCAGGAGCTG TTCTACAGAA ATCCTGTATT TTCTGGAGTT 720

ACACTGCCCG AATGTTCGGA CAGAGTCACT CTCCAGCAGC GTTTCCCTAC AATCACACCT 780

ATTAGCCTGG ATCTGGCACA GGAGTGTCTA GAGATAGATC CAGAAAGACG GGCTCAGTGT 840

TCGGAGCTGT TAGAGCATCC ACTGTTTACA CAAGACTCCT TCCACATCAG ATTTTTGGAC 900

GAGCTAAATT CTAAGATCCA AAAAGACCAC AGAGAGAACT CTACCTTTCC CAAAATAACC 960

AAAAACCCAA GAAAGAATGA AAGGGATGAG AAAAACTGTA GAGGCAAGGA CAAGAAACAA 1020

CCTGAAGACA TGGATGAAAA AGTCAACAAG GAAAAGATGG AGAAAGTAAA GGGA 1074

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+vlkcr++dtg++vaikkf++s+ddk+vkkia reikll+ql+h+nl

Q: 4     YESLGPVGEGSYGTVLKCRHRDTGRLVAIKKFMDSDDDKTVKKIAHREIKLLRQLRHDNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev++r++++ylvfe+vd+t+ld+l+++p G+e ++ +++lyqil+a +fch++nii

Q: 64    VNLLEVWKRRRRWYLVFEFVDRTLLDDLQQNPSGLEMNTCRQYLYQILRAASFCHQQNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla..apgdvytdyvatrwyrapellvgdtkyGk  178

         hrdikpenilis++gvvklcdfGfar++a  ++g   tdyvatrwyrapellvgd+kyGk

Q: 124   HRDIKPENILISQEGVVKLCDFGFARTVAstSEGSLLTDYVATRWYRAPELLVGDIKYGK  183

         ****************************944567799***********************

S: 179   svdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklp  238

         +vdvwa+Gc+l e+ltG+plfpg+sd+dq+y+i++++G+l+++hq++f++n+vf+Gv+lp

Q: 184   PVDVWALGCVLLEMLTGQPLFPGDSDLDQIYQIIRCFGNLTSHHQELFYRNPVFSGVTLP  243

         ************************************************************

S: 239   evedleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e +d+ +l++++p+++++ ldl+++cl++dp++r +c+ell+h++f

Q: 244   ECSDRVTLQQRFPTITPISLDLAQECLEIDPERRAQCSELLEHPLF  289

         *******************************************998

Domain Sequence
(FASTA)

YESLGPVGEG SYGTVLKCRH RDTGRLVAIK KFMDSDDDKT VKKIAHREIK LLRQLRHDNL 60

VNLLEVWKRR RRWYLVFEFV DRTLLDDLQQ NPSGLEMNTC RQYLYQILRA ASFCHQQNII 120

HRDIKPENIL ISQEGVVKLC DFGFARTVAS TSEGSLLTDY VATRWYRAPE LLVGDIKYGK 180

PVDVWALGCV LLEMLTGQPL FPGDSDLDQI YQIIRCFGNL TSHHQELFYR NPVFSGVTLP 240

ECSDRVTLQQ RFPTITPISL DLAQECLEID PERRAQCSEL LEHPLF 286

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013