EKS-ORN-00186

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00186

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	516.0	3.6E-155	90	383	294

Status

Unreviewed

Ensembl Protein

ENSONIP00000014967

UniProt Accession

I3K1H2;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000011890	ENSONIP00000014967	ENSONIT00000014979

Organism

Oreochromis niloticus

Functional Description

Protein Length

465

Protein Sequence
(FASTA)

MAMTGGTAAA LPMSNHTRER VTVAKLTLEN FYSTLLTQHE EREMRQKKLE KAMEEEGLPD 60

EEKVMRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLSEEAT QFYIAETVLA IDSIHQLGFI HRDIKPDNLL LDSRGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SERAKDLILR 360

FCTDAENRIG AVSVDEIKSH QFFELVDWEH IRERPAAISI EIKSIDDTSN FDDFPESDIL 420

QPETANATEP DFKSKDWVFL NYTYKRFEGL TQRGTIPTYM KAGKA 465

Nucleotide Sequence
(FASTA)

ATGGCCATGA CGGGAGGGAC TGCAGCTGCC CTTCCCATGA GCAACCACAC CCGAGAGAGG 60

GTGACAGTGG CCAAGCTGAC ACTGGAAAAT TTCTACAGCA CTCTGCTCAC CCAGCACGAG 120

GAGCGGGAGA TGAGGCAGAA AAAACTCGAG AAGGCCATGG AAGAAGAGGG TTTACCAGAT 180

GAGGAGAAAG TAATGCGGCG CTCTCAGCAT GCCCGGAAGG AGACCGAGTT TTTACGACTG 240

AAGAGGACGC GACTCGGTTT GGATGACTTT GAGTCCCTAA AGGTCATTGG ACGAGGTGCT 300

TTTGGAGAGG TGCGTTTGGT ACAGAAGAAA GACACAGGCC ACATTTATGC CATGAAGATT 360

TTAAGGAAAG CAGACATGCT GGAGAAAGAA CAGGTCGCTC ACATCCGGGC AGAGAGGGAT 420

ATTCTGGTGG AGGCGGATGG TGCCTGGGTG GTCAAGATGT TCTACAGCTT CCAGGACAAG 480

AGAAACCTCT ACCTCATTAT GGAGTTCCTG CCTGGAGGTG ACATGATGAC GCTGCTGATG 540

AAGAAGGACA CTCTGTCTGA AGAGGCCACT CAGTTCTACA TCGCAGAGAC AGTACTGGCC 600

ATTGACTCCA TCCACCAGCT GGGATTCATC CACAGAGACA TCAAACCGGA CAACCTGCTG 660

CTGGACTCCA GAGGACATGT GAAACTGTCA GATTTTGGCT TGTGTACTGG GCTGAAGAAG 720

GCTCATCGCA CAGAATTTTA CAGGAACCTG ACGCACAACC CACCCAGTGA TTTCTCCTTT 780

CAAAATATGA ACTCCAAGAG GAAAGCAGAG ACCTGGAAGA AGAACCGGAG ACAGCTGGCT 840

TATTCCACTG TGGGAACGCC AGACTACATC GCTCCTGAAG TGTTCATGCA GACGGGGTAC 900

AACAAACTGT GCGACTGGTG GTCTCTGGGT GTGATTATGT ATGAGATGCT CATCGGTTAT 960

CCACCCTTCT GCTCAGAGAC ACCACAGGAG ACGTACAGGA AGGTTATGAA CTGGAAGGAA 1020

ACGCTCGTCT TTCCACCTGA AGTTCCCATC TCAGAGAGAG CCAAAGACTT AATATTAAGG 1080

TTTTGCACAG ATGCAGAGAA CAGGATTGGC GCTGTGAGCG TGGACGAGAT CAAGAGCCAC 1140

CAGTTCTTTG AGTTGGTGGA TTGGGAGCAC ATCAGGGAGC GGCCAGCCGC CATCTCCATA 1200

GAAATCAAAA GTATTGATGA CACCTCTAAC TTTGACGACT TCCCTGAATC GGACATCCTT 1260

CAGCCAGAAA CAGCTAACGC AACGGAGCCT GACTTCAAAT CAAAGGACTG GGTGTTCCTC 1320

AACTACACCT ACAAACGCTT TGAGGGCCTG ACTCAGCGAG GGACCATCCC CACATACATG 1380

AAGGCAGGGA AGGCTTGA 1398

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEATQFYIAETVLAIDSIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d++Gh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDSRGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++dae+r+g+  vdeik+h+ff

Q: 330   ETYRKVMNWKETLVFPPEVPISERAKDLILRFCTDAENRIGAVSVDEIKSHQFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLSEEA TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSRGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISERAKDLIL RFCTDAENRI GAVSVDEIKS HQFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013