EKS-ORN-00080

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00080

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	387.8	3.6E-116	141	422	282

Status

Unreviewed

Ensembl Protein

ENSONIP00000015669

UniProt Accession

I3K3H5;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100697880

Gene Synonyms/Alias

LOC100697880;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000012440	ENSONIP00000015670	ENSONIT00000015684
ENSONIG00000012440	ENSONIP00000015669	ENSONIT00000015683

Organism

Oreochromis niloticus

Functional Description

Protein Length

494

Protein Sequence
(FASTA)

MDRMKIIKRR LSMSLRSARP VDDSLSELAE QMALDEASTA RDNGIVHENV KMGSDGESDQ 60

ASGTSSDEVQ SPVRVRMRNN HHRRISNEDI NKRLSLPADI RLPEGYLEKF AMNSPPFDKP 120

MSRRLRRASL SEIGFGKLET YIKLDKLGEG TYATVFKGRS KLTDNLVALK EIRLEHEEGA 180

PCTAIREVSL LKDLKHANIV TLHDIIHTDK CLTLVFEYLE KDLKQYMDDC GSIMSVHNVK 240

IFLFQLLRGL AYCHRRKVLH RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT 300

LWYRPPDVLL GSTEYSTPID MWGVGCIFYE MITGRPLFPG STVEDELHLI FRILGTPTEE 360

TWPGITTSEE FKTYNFPRYH AEPLVNHAPR IDSDGHDLLS KLLQFEAKKR ILAEDALRHA 420

YFKCLGEQVQ TLADTASIFS VKGIQLQKDP GKRSSVYPES SMANKLGSAP SQYFQREAAN 480

PRAQSHNLSS TSTG 494

Nucleotide Sequence
(FASTA)

ATGGACAGGA TGAAGATCAT CAAGCGGAGG CTGTCCATGT CTCTACGCAG CGCTCGGCCC 60

GTCGATGACT CTCTGTCCGA ACTTGCCGAA CAGATGGCCT TGGATGAGGC ATCCACAGCT 120

AGGGACAATG GCATTGTCCA TGAAAATGTG AAGATGGGTT CAGATGGGGA GAGTGACCAA 180

GCATCCGGGA CGTCCTCTGA TGAGGTTCAG AGTCCAGTGA GGGTCCGTAT GAGGAACAAT 240

CACCATCGGC GCATCTCTAA TGAGGACATA AACAAACGTT TGTCTCTCCC AGCTGATATC 300

AGGCTACCAG AGGGCTACTT GGAGAAGTTT GCCATGAACA GCCCGCCCTT TGACAAACCC 360

ATGAGCCGCA GGCTACGACG CGCATCATTG TCTGAGATCG GCTTTGGGAA ACTTGAAACC 420

TACATCAAAC TGGACAAACT AGGAGAGGGG ACCTATGCGA CAGTATTTAA GGGGCGAAGT 480

AAGTTAACAG ATAACTTGGT CGCCCTGAAA GAGATCCGCC TAGAGCACGA GGAGGGCGCG 540

CCCTGCACCG CTATCCGAGA AGTGTCTCTA CTGAAAGACT TGAAGCACGC CAATATTGTC 600

ACTCTCCATG ACATTATCCA CACTGACAAG TGCCTAACAC TCGTGTTTGA GTATCTGGAA 660

AAAGACCTGA AGCAATATAT GGACGACTGT GGGAGCATCA TGAGCGTTCA CAATGTTAAG 720

ATCTTCTTAT TTCAGCTTTT AAGAGGTCTG GCGTACTGCC ACAGGAGGAA GGTCCTCCAT 780

AGAGACCTGA AACCCCAGAA CCTGCTCATC AATGAAAAAG GAGAGCTCAA ACTGGCAGAC 840

TTTGGTTTGG CTCGAGCTAA GTCGGTACCT ACGAAGACCT ACTCAAATGA AGTTGTGACA 900

TTATGGTACC GACCACCAGA TGTGCTGCTG GGCTCCACTG AGTACTCTAC ACCCATTGAC 960

ATGTGGGGTG TGGGCTGCAT CTTCTATGAA ATGATCACAG GCAGACCTCT CTTCCCTGGA 1020

TCGACTGTGG AGGATGAGCT TCATCTCATA TTCCGCATCC TTGGTACTCC CACAGAAGAG 1080

ACTTGGCCTG GTATCACAAC CAGTGAAGAG TTTAAGACAT ACAATTTCCC CCGCTACCAC 1140

GCAGAACCCC TTGTGAACCA CGCACCCAGG ATAGACAGTG ATGGTCATGA CTTGCTCTCA 1200

AAGCTCTTAC AGTTTGAAGC AAAGAAGCGG ATATTGGCTG AGGATGCTCT CAGACACGCT 1260

TATTTCAAAT GTCTTGGAGA ACAGGTTCAG ACTCTGGCTG ATACTGCATC CATCTTCTCT 1320

GTAAAAGGCA TTCAGCTCCA GAAAGATCCA GGAAAGAGAT CCTCAGTCTA CCCAGAGTCA 1380

TCGATGGCCA ATAAGCTAGG CTCCGCACCC TCGCAGTACT TCCAGAGAGA GGCAGCCAAT 1440

CCCAGGGCTC AGAGTCACAA TCTCTCCTCT ACTTCCACTG GCTGA 1485

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 141   YIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  199

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k l+Lvfe+le+dLk++++++ +  +s ++vk +l+qll+glay+H++k

Q: 200   VTLHDIIH-TDKCLTLVFEYLEKDLKQYMDDCGS-IMSVHNVKIFLFQLLRGLAYCHRRK  257

         ********.99**********************9.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 258   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST  317

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

          +D+W+vgci+ e++t +plf+g++  d+l+ if++lgtp+e++wp++++ +e+k ++fp

Q: 318   PIDMWGVGCIFYEMITGRPLFPGSTVEDELHLIFRILGTPTEETWPGITTSEEFKtYNFP  377

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +++++ l ++ +++++++ dll+kll+++ kkRi a++al+h yf

Q: 378   RYHAEPLVNHAPRIDSDGHDLLSKLLQFEAKKRILAEDALRHAYF  422

         ********************************************9

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVFKGRS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTDK CLTLVFEYLE KDLKQYMDDC GSIMSVHNVK IFLFQLLRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSTEYSTPID 180

MWGVGCIFYE MITGRPLFPG STVEDELHLI FRILGTPTEE TWPGITTSEE FKTYNFPRYH 240

AEPLVNHAPR IDSDGHDLLS KLLQFEAKKR ILAEDALRHA YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013