EKS-ORN-00084

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00084

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	372.6	1.5E-111	40	337	298

Status

Unreviewed

Ensembl Protein

ENSONIP00000015861

UniProt Accession

I3K416;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK9

Gene Synonyms/Alias

CDK9;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000012601	ENSONIP00000015861	ENSONIT00000015876

Organism

Oreochromis niloticus

Functional Description

Protein Length

393

Protein Sequence
(FASTA)

MQRDKTSNAT GAEKPDREAA IMSKYYDGVE FPFCDEFSKY EKMAKIGQGT FGEVFKAKHR 60

QTGKKVALKK VLMENEKEGF PITALREIKI LQLLKHENVV NLIEICRTKA TQFNRYKGSI 120

YLVFDFCEHD LAGLLSNANV KFTLAEIKKV MQMLLNGLYY IHRNKILHRD MKAANVLITR 180

DGVLKLADFG LARAFSLAKN SQGNRYTNRV VTLWYRPPEL LLGERDYGPP IDLWGAGCIM 240

AEMWTRSPIM QGNTEQHQLT LISQLCGSIT AEVWPGVDKK YELYQKMELP KGQKRKVKDR 300

LKAYVKDPYA LDLIDKLLVL DPAQRIDSDD ALNHDFFWSD PMPSDLKNML STHNTSMFEY 360

LAPPRRRGHM PQQQPNQNRN PATTSQTEFD RVF 393

Nucleotide Sequence
(FASTA)

ATGCAGCGGG ACAAGACAAG CAACGCCACC GGGGCTGAAA AGCCCGATCG GGAGGCCGCC 60

ATCATGTCGA AGTACTACGA CGGAGTGGAG TTCCCTTTCT GTGACGAGTT CTCCAAGTAC 120

GAGAAAATGG CCAAGATCGG ACAAGGAACC TTTGGGGAGG TGTTCAAAGC GAAGCACCGA 180

CAGACAGGGA AGAAAGTTGC ACTGAAGAAA GTGCTGATGG AAAACGAGAA AGAAGGGTTC 240

CCAATCACAG CTCTGAGAGA GATCAAAATC CTTCAACTGC TCAAGCACGA GAACGTTGTC 300

AATCTGATCG AGATCTGCAG GACCAAAGCC ACTCAGTTTA ACAGGTACAA AGGCAGCATC 360

TACTTGGTGT TTGACTTCTG TGAGCATGAC CTGGCTGGGC TGCTGAGCAA TGCCAACGTG 420

AAGTTCACGC TGGCAGAGAT CAAGAAGGTG ATGCAGATGC TGCTCAATGG GCTGTACTAC 480

ATCCACAGGA ACAAGATCCT TCACAGAGAC ATGAAGGCAG CTAATGTGCT CATAACCAGA 540

GACGGCGTCC TGAAGCTGGC TGACTTTGGT TTGGCTCGAG CCTTCAGCCT GGCCAAGAAC 600

AGCCAGGGGA ACCGCTACAC TAACCGCGTG GTGACGCTGT GGTACCGACC TCCAGAGCTG 660

CTGTTGGGTG AGCGAGACTA CGGGCCTCCA ATCGACCTGT GGGGGGCTGG CTGCATCATG 720

GCCGAGATGT GGACACGGAG TCCGATCATG CAGGGGAACA CGGAGCAGCA CCAGCTGACC 780

CTCATCAGCC AGCTCTGCGG CTCCATCACG GCAGAGGTGT GGCCCGGTGT AGACAAGAAG 840

TATGAGCTGT ACCAGAAGAT GGAGCTGCCC AAAGGTCAGA AGAGGAAAGT GAAGGACCGC 900

CTCAAAGCTT ACGTCAAAGA CCCGTATGCC CTGGACCTCA TTGACAAGCT GCTGGTCCTG 960

GACCCGGCAC AGCGAATCGA CAGTGACGAC GCCCTCAACC ACGACTTCTT CTGGTCAGAC 1020

CCGATGCCGT CAGACCTCAA GAACATGCTC TCCACCCACA ACACGTCCAT GTTTGAGTAC 1080

CTGGCCCCAC CTCGGCGGAG AGGACACATG CCCCAGCAGC AGCCTAATCA GAACCGGAAC 1140

CCGGCCACCA CGAGCCAGAC AGAGTTCGAC CGCGTGTTTT AA 1182

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yek++kig+Gt+g+v+kak+++tg++vAlKk+ +e+ekeg+pitalrEi++l+ lkh+n+

Q: 40    YEKMAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENV  99

         99**********************************************************

S: 61    vkLlevva.......kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         v+L+e++        + k ++yLvf+f+e+dL+ ll++ +  k++l+e+k+++++ll+gl

Q: 100   VNLIEICRtkatqfnRYKGSIYLVFDFCEHDLAGLLSNANV-KFTLAEIKKVMQMLLNGL  158

         ********99999977889**********************.******************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlaraf....ssplktytkevvTlwYraP  169

          y+H+nkilHRD+K++N+Li+++g+lklaDfGlaraf    +s+ ++yt++vvTlwYr+P

Q: 159   YYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFslakNSQGNRYTNRVVTLWYRPP  218

         *************************************7665555558*************

S: 170   elLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevs  229

         elLlg+++Y+  +D+W++gci+ae++tr+p++qg++e++ql+ i++l+g+++ +vwp+v

Q: 219   ELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITAEVWPGVD  278

         **********************************************************97

S: 230   k.lpeyk.ksfpkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

         k ++ y+ +++pk +k+k+k+++k++ ++  aldl++kll ldp++Ri++++al+h++f

Q: 279   KkYELYQkMELPKGQKRKVKDRLKAYVKDpyALDLIDKLLVLDPAQRIDSDDALNHDFF  337

         526777789999*9999******988766579*************************98

Domain Sequence
(FASTA)

YEKMAKIGQG TFGEVFKAKH RQTGKKVALK KVLMENEKEG FPITALREIK ILQLLKHENV 60

VNLIEICRTK ATQFNRYKGS IYLVFDFCEH DLAGLLSNAN VKFTLAEIKK VMQMLLNGLY 120

YIHRNKILHR DMKAANVLIT RDGVLKLADF GLARAFSLAK NSQGNRYTNR VVTLWYRPPE 180

LLLGERDYGP PIDLWGAGCI MAEMWTRSPI MQGNTEQHQL TLISQLCGSI TAEVWPGVDK 240

KYELYQKMEL PKGQKRKVKD RLKAYVKDPY ALDLIDKLLV LDPAQRIDSD DALNHDFF 298

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013