EKS-ORN-00546

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00546

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	503.4	2.0E-151	158	415	258

Status

Unreviewed

Ensembl Protein

ENSONIP00000017842

UniProt Accession

I3K9P8;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000014195	ENSONIP00000017842	ENSONIT00000017857
ENSONIG00000014195	ENSONIP00000017843	ENSONIT00000017858

Organism

Oreochromis niloticus

Functional Description

Protein Length

453

Protein Sequence
(FASTA)

MLTGPKMEDQ PSFPSVSIPC HNEQRDKKKR YTVYKVIVNV GQQEWFVFRR YAEFDKLFNT 60

LRKQFPSMNL KIPAKRIFGD NFDPEFIKQR RAGLHEFIKK IVSHPQLSNH PDVRAFLLME 120

KMEQISDASE DEDEKNNSTS RNINLGPSAN PQAKPTDFDF LKVIGKGSFG KVFLAKRKHD 180

GKFYAVKILQ KKIILNRKEQ KHIMAERNVL LKNVKHPFLV GLHYSFQTKD KLYFVLDFIN 240

GGELFFHLQR ERTFPEPRAK FYIAEMASAL GYLHSLTIVY RDLKPENILL DHEGHIVLTD 300

FGLCKEGISQ KDTTTTFCGT PEYLAPEVLK KLPYDRTVDW WCLGSVLYEM LFGLPPFYSR 360

DTHEMYDNIL HKPLTRRPGA SNTAWSLLDG LLEKDGKRRL GYREDFIEIR RHSFFSSINW 420

DDLEQKKIPP PFTPLVVNIF SCNQNRLGIL HLF 453

Nucleotide Sequence
(FASTA)

ATGCTGACCG GCCCTAAGAT GGAGGACCAA CCCAGTTTTC CCAGTGTCAG CATCCCTTGC 60

CACAATGAGC AGAGGGACAA GAAAAAGCGC TACACGGTTT ACAAAGTGAT TGTCAATGTT 120

GGACAACAGG AATGGTTTGT CTTCAGGCGA TATGCAGAGT TTGATAAACT CTTTAACACA 180

TTGAGGAAAC AGTTTCCATC TATGAACTTG AAAATTCCAG CTAAAAGGAT ATTTGGGGAC 240

AACTTTGACC CGGAGTTCAT CAAGCAAAGA AGAGCCGGGT TACATGAGTT CATCAAAAAA 300

ATCGTCTCAC ATCCTCAGCT TTCCAACCAT CCAGATGTGA GGGCATTTTT ACTAATGGAA 360

AAAATGGAAC AAATATCAGA TGCCTCTGAA GATGAAGATG AAAAGAACAA CTCTACCTCC 420

AGAAACATCA ACCTGGGACC CTCTGCAAAT CCACAAGCCA AGCCCACAGA CTTTGACTTT 480

TTAAAAGTCA TAGGAAAAGG GAGTTTTGGG AAGGTTTTCC TCGCTAAACG AAAACACGAT 540

GGAAAGTTTT ATGCTGTCAA GATCTTACAA AAAAAGATCA TTCTCAACAG GAAAGAGCAA 600

AAACACATCA TGGCAGAACG CAACGTTTTG CTGAAGAACG TGAAACATCC CTTCCTAGTC 660

GGGCTTCATT ATTCCTTCCA GACTAAAGAC AAGTTGTACT TCGTGTTGGA TTTCATCAAT 720

GGAGGAGAAC TTTTCTTTCA TCTTCAAAGA GAAAGGACCT TTCCAGAGCC CAGAGCAAAG 780

TTCTACATTG CTGAAATGGC AAGTGCGCTG GGATACCTGC ATTCTCTCAC GATTGTTTAC 840

AGAGACTTAA AGCCAGAAAA TATCCTTCTT GACCACGAGG GGCATATCGT ACTCACAGAC 900

TTTGGATTGT GCAAGGAAGG CATTTCCCAG AAGGATACTA CCACTACATT TTGTGGAACA 960

CCTGAGTACT TAGCTCCAGA GGTCTTGAAG AAGCTGCCGT ATGATCGCAC AGTAGACTGG 1020

TGGTGTCTGG GCTCAGTGCT GTATGAAATG CTCTTTGGTC TACCACCTTT CTACAGCAGG 1080

GACACACACG AGATGTATGA CAACATCCTC CACAAGCCGC TAACCAGGCG TCCCGGTGCC 1140

TCCAACACAG CCTGGTCTCT CCTCGACGGG CTGCTGGAGA AAGATGGCAA GCGCAGACTG 1200

GGATACAGGG AAGACTTTAT TGAGATCAGA AGACACAGCT TCTTCTCTTC CATCAACTGG 1260

GATGACCTTG AGCAGAAGAA GATCCCTCCC CCTTTTACAC CACTTGTGGT AAATATTTTT 1320

TCCTGTAATC AAAACCGCCT GGGTATTTTA CACTTATTTT GA 1362

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkv+lakrk+d+kfyavk+lqkk+il++ke+khimaernvllknvkhp

Q: 158   FDFLKVIGKGSFGKVFLAKRKHDGKFYAVKILQKKIILNRKEQKHIMAERNVLLKNVKHP  217

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt++klyfvld++nggelffhlqrer+f+epra+fy ae+asalgylhsl

Q: 218   FLVGLHYSFQTKDKLYFVLDFINGGELFFHLQRERTFPEPRAKFYIAEMASALGYLHSLT  277

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenilld +gh+vltdfglcke+i ++dtt+tfcgtpeylapevl+k pydrt

Q: 278   IVYRDLKPENILLDHEGHIVLTDFGLCKEGISQKDTTTTFCGTPEYLAPEVLKKLPYDRT  337

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclg+vlyeml+glppfysrd+ emydnil+kpl  +pg s++a++ll++llekd k

Q: 338   VDWWCLGSVLYEMLFGLPPFYSRDTHEMYDNILHKPLTRRPGASNTAWSLLDGLLEKDGK  397

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg +edf+ei+ h ff

Q: 398   RRLGYREDFIEIRRHSFF  415

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVFLAKR KHDGKFYAVK ILQKKIILNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TKDKLYFVLD FINGGELFFH LQRERTFPEP RAKFYIAEMA SALGYLHSLT 120

IVYRDLKPEN ILLDHEGHIV LTDFGLCKEG ISQKDTTTTF CGTPEYLAPE VLKKLPYDRT 180

VDWWCLGSVL YEMLFGLPPF YSRDTHEMYD NILHKPLTRR PGASNTAWSL LDGLLEKDGK 240

RRLGYREDFI EIRRHSFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013