EKS-ORN-00361

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00361

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	436.0	7.8E-131	222	509	288

Status

Unreviewed

Ensembl Protein

ENSONIP00000020247

UniProt Accession

I3KGK2;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000016072	ENSONIP00000020247	ENSONIT00000020264

Organism

Oreochromis niloticus

Functional Description

Protein Length

520

Protein Sequence
(FASTA)

LFVSCPAAGQ NPDHVLQGTG VKPEARRPGD GPTIAPEDLP RSLSCYCSGH CPDDAINNTC 60

QTNGQCFAII EQDEHGEVQL TSGCMKYEGS HFQCKDSPNA QTRRTIECCN TDLCNRDLQP 120

TLPPLAPTGN VEHSCRRSPH WLAFLISMTV CCCTLICVTV VYYYSHFCLY DRQRYHKNHK 180

DQEHDVFIRE GESLRDLIHQ SQSSGSGSGL PLLVQRTIAK QIQMVRQIGK GRYGEVWLGR 240

WRGEKVAVKV FFTREEASWF RETEIYQTVL MRHENILGFI AADIKGTGAF TQLFLITDYH 300

ENGSLYDFLK LTTLDTQALL RLAYSAACGL CHLHTEIYGT QGKPAIAHRD LKSKNILIKK 360

NGSCCIADLG LAVKFNSDTN EVDIPLSTRV GTRRYMAPEV LDESLNKNHF QAYIMADMYS 420

FGLIVWEMTR RCVTGGIVED YQLPYYDMVP SDPSYEDMLE VVCVKGLRPT VSNRWNSDEC 480

LRAMLKLMSE CWAHNPASRL TILRVKKTLA KMVESQDIKI 520

Nucleotide Sequence
(FASTA)

CTGTTTGTTT CGTGTCCAGC TGCAGGTCAG AACCCGGACC ACGTCCTGCA GGGGACGGGG 60

GTGAAACCCG AGGCCCGGCG CCCTGGCGAC GGTCCCACCA TCGCACCCGA GGACCTCCCT 120

CGATCCCTCA GCTGCTACTG CTCGGGTCAC TGCCCCGACG ACGCCATCAA CAACACCTGC 180

CAGACGAATG GTCAGTGCTT CGCCATCATC GAGCAGGACG AGCACGGAGA GGTGCAGCTC 240

ACCTCCGGCT GCATGAAGTA TGAAGGCTCT CACTTCCAGT GCAAGGACTC CCCCAACGCT 300

CAGACCAGGA GGACCATCGA GTGCTGCAAC ACAGACTTGT GCAACAGAGA CCTGCAGCCC 360

ACGCTGCCCC CGCTGGCCCC CACCGGTAAC GTGGAACACA GTTGCAGGCG AAGCCCCCAC 420

TGGCTGGCCT TCCTGATCTC CATGACGGTC TGCTGTTGCA CGCTGATCTG CGTCACCGTG 480

GTTTACTACT ACAGTCATTT TTGTCTGTAC GACCGGCAGC GGTATCATAA GAACCATAAG 540

GACCAGGAGC ATGATGTCTT CATCCGGGAG GGCGAGTCGC TCAGAGACCT CATTCATCAG 600

TCTCAGAGCT CAGGCAGCGG CTCAGGGCTC CCTCTGCTGG TGCAGCGGAC CATCGCCAAG 660

CAGATCCAGA TGGTGCGTCA GATCGGAAAA GGGCGGTACG GCGAGGTGTG GCTGGGCCGC 720

TGGAGGGGCG AGAAGGTCGC CGTCAAAGTC TTCTTCACCC GAGAGGAAGC CAGCTGGTTC 780

AGGGAGACGG AGATCTACCA AACGGTCCTG ATGAGGCATG AGAACATCCT CGGCTTCATC 840

GCGGCGGACA TTAAGGGCAC GGGCGCCTTC ACACAGCTCT TCCTCATCAC CGACTACCAC 900

GAGAACGGCT CGCTGTACGA CTTCCTGAAG CTGACCACGC TGGACACGCA GGCGCTGCTG 960

CGGCTCGCCT ACTCGGCCGC CTGCGGCCTC TGCCACCTGC ACACGGAGAT CTACGGCACG 1020

CAGGGCAAGC CGGCCATCGC CCACCGCGAC CTGAAGAGCA AGAACATCCT GATCAAGAAG 1080

AACGGCTCCT GCTGCATCGC CGACCTCGGC CTCGCCGTCA AGTTCAACAG TGACACGAAC 1140

GAGGTGGACA TCCCCCTGAG CACCCGGGTG GGGACGAGAC GCTACATGGC CCCTGAGGTC 1200

CTCGACGAGA GCCTCAACAA GAACCACTTC CAGGCCTACA TCATGGCCGA CATGTACAGC 1260

TTCGGACTCA TCGTCTGGGA GATGACCCGA CGCTGTGTCA CCGGGGGTAT CGTGGAGGAC 1320

TACCAGCTGC CGTACTATGA CATGGTGCCC TCTGACCCCT CCTATGAGGA CATGCTGGAG 1380

GTGGTGTGTG TTAAGGGCCT GCGGCCGACG GTGTCTAACC GCTGGAACAG CGACGAGTGC 1440

CTCCGGGCCA TGCTGAAGCT GATGTCAGAG TGCTGGGCTC ATAACCCCGC CTCCCGCCTC 1500

ACCATCCTCA GAGTGAAGAA GACGCTCGCC AAGATGGTGG AGTCCCAGGA CATCAAGATC 1560

TGA 1563

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw +++rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 222   IQMVRQIGKGRYGEVWLGRWRGEKVAVKVFFTREEASWFRETEIYQTVLMRHENILGFIA  281

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++  t+l+l+t+yhe+gsL+d+Lk +tld++ llrla+s+a+Gl+hLH+ei gt+

Q: 282   ADIKGTGAFTQLFLITDYHENGSLYDFLKLTTLDTQALLRLAYSAACGLCHLHTEIYGTQ  341

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskNil+kk+++cciaDlGLa+k++++++e+d+  +++vGt+RYmaPE

Q: 342   G--KPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLSTRVGTRRYMAPE  399

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+a+ +aD+Ys+gL++WE+++Rc + +++ve+y+lp++++v+sdPs+e+m

Q: 400   VLDESLNKNHFQAYIMADMYSFGLIVWEMTRRCVT-GGIVEDYQLPYYDMVPSDPSYEDM  458

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

          evv++k lrP+++++w+++e+l+++ kl++ecW+++p++Rlt lrvkk+l

Q: 459   LEVVCVKGLRPTVSNRWNSDECLRAMLKLMSECWAHNPASRLTILRVKKTL  509

         *************************************************97

Domain Sequence
(FASTA)

IQMVRQIGKG RYGEVWLGRW RGEKVAVKVF FTREEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGAFT QLFLITDYHE NGSLYDFLKL TTLDTQALLR LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GSCCIADLGL AVKFNSDTNE VDIPLSTRVG TRRYMAPEVL 180

DESLNKNHFQ AYIMADMYSF GLIVWEMTRR CVTGGIVEDY QLPYYDMVPS DPSYEDMLEV 240

VCVKGLRPTV SNRWNSDECL RAMLKLMSEC WAHNPASRLT ILRVKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013