EPS-ORN-00038

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORN-00038

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	203.7	5.6E-60	148	401	254

Status

Unreviewed

Ensembl Protein

ENSONIP00000021880

UniProt Accession

I3KL85;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000017353	ENSONIP00000021880	ENSONIT00000021899

Organism

Oreochromis niloticus

Functional Description

Protein Length

625

Protein Sequence
(FASTA)

MAGSAAEEKT FRRFLELFIR EMRMPLQEGD PLPTRPLSDL VSEDEVEGEC LDLCLQHLYK 60

YNCPCSLAAA LARATADSLL QTDLSIHHLN KTVEDGADPL PRGSTETYIQ MESVKLARLV 120

FNRLFETCCL WLKELPFRRR PQPYYETSIH AIKNMRRKME DKHVIIPDFN TLFNIQDQEE 180

QAFFAVFDGH GGVDAAIYAA NHLHVNLVRQ ESFSQDPSEA LCRAFKVTDE RFVKKASREN 240

LRCGTTGVVT FLRGRTLYVA WLGDSQVILV RRGQVVELMK PHKPDREDEK QRIEALGGCV 300

IWFGTWRVNG SLSVSRAIGD SEHKPYICGD ADHGVFPLDG SEDYLILACD GFWDTVNPDE 360

AVRVVSDHLQ ENTGDTTMVA HKLVASARDA GSSDNITVIV VFLRDPRSPP PTSTEEEEEG 420

VVEGEVADEE EVAEVEEEEQ EEEEEEDEAV RVERDGGEGG SNADNGGKSR GGWPLQQCSA 480

PADLGYEDRT DSFTDRTSLS LLGPALEGRI SLTRGSFGVS PDLFAASHIF RERALRRRSC 540

VPFQESSISS FTDPLWPHTA MLLGQAVRRS RKLGYGSRRW GRRLPSRSRE LLGLLPSGPL 600

LPHMQRYSNR KSGVAVPQLP HDATI 625

Nucleotide Sequence
(FASTA)

ATGGCCGGCT CTGCAGCAGA GGAGAAAACC TTCCGACGGT TCTTGGAGCT CTTTATTCGG 60

GAGATGAGGA TGCCTCTGCA GGAGGGCGAC CCGCTGCCGA CGCGCCCCTT GTCGGACCTG 120

GTGTCTGAGG ACGAAGTGGA GGGGGAATGC CTCGACTTGT GTCTCCAGCA CCTCTACAAA 180

TATAACTGCC CATGCTCCCT GGCTGCCGCC TTGGCCAGAG CCACAGCAGA CAGCCTCCTG 240

CAGACTGACC TCTCCATTCA CCACCTCAAT AAGACTGTAG AAGATGGAGC TGACCCATTA 300

CCACGTGGTT CAACGGAAAC ATACATACAG ATGGAGTCTG TGAAGCTGGC CCGGCTGGTG 360

TTTAATAGAC TGTTTGAGAC GTGCTGCCTC TGGCTGAAGG AGCTCCCCTT CCGCCGCCGT 420

CCACAACCAT ATTATGAGAC GTCCATCCAC GCCATCAAGA ACATGAGGCG CAAGATGGAG 480

GACAAGCACG TCATCATCCC TGACTTCAAC ACACTCTTCA ATATTCAGGA TCAGGAAGAG 540

CAGGCTTTCT TTGCTGTGTT TGACGGTCAC GGAGGTGTGG ATGCTGCCAT TTATGCAGCC 600

AATCACCTTC ACGTGAACTT AGTCCGGCAG GAATCCTTCA GCCAGGACCC CAGCGAGGCG 660

CTCTGCAGAG CCTTCAAAGT CACCGACGAA CGCTTCGTGA AGAAGGCCTC GCGAGAGAAC 720

CTACGTTGTG GCACAACAGG CGTGGTGACG TTCCTGCGGG GCCGGACGTT GTACGTGGCC 780

TGGCTTGGAG ACTCCCAGGT CATTCTGGTC AGGAGAGGGC AGGTGGTGGA GCTGATGAAA 840

CCACATAAAC CAGACAGAGA GGATGAGAAG CAGAGGATCG AGGCTCTCGG AGGTTGTGTG 900

ATCTGGTTCG GCACGTGGAG GGTCAATGGC AGCCTGTCTG TATCCAGAGC GATAGGTGAC 960

TCGGAGCACA AACCCTACAT CTGTGGTGAT GCAGACCATG GCGTCTTCCC ATTGGATGGT 1020

TCAGAAGACT ACCTGATTCT GGCCTGCGAT GGCTTCTGGG ACACGGTGAA TCCAGATGAG 1080

GCGGTGCGCG TGGTCAGTGA TCATCTCCAG GAGAACACTG GGGACACCAC CATGGTAGCT 1140

CACAAGCTGG TGGCCTCAGC CCGGGATGCG GGCTCTAGCG ATAATATCAC TGTCATAGTG 1200

GTCTTCTTGC GGGACCCGCG CTCGCCGCCA CCCACCAGCA CCGAGGAGGA GGAGGAGGGT 1260

GTGGTGGAGG GAGAGGTGGC GGACGAGGAG GAGGTAGCAG AGGTGGAGGA GGAGGAGCAA 1320

GAAGAGGAGG AGGAGGAAGA TGAAGCGGTC AGGGTAGAGC GTGACGGCGG AGAGGGAGGA 1380

AGCAATGCGG ACAATGGGGG GAAGAGCCGT GGAGGCTGGC CCCTGCAGCA GTGCTCAGCG 1440

CCCGCCGACC TTGGCTATGA AGACCGAACT GACTCGTTCA CGGACAGAAC TAGCCTCAGC 1500

CTGCTGGGGC CGGCGCTGGA GGGCCGCATC TCGCTGACCC GTGGCTCTTT CGGCGTTAGC 1560

CCCGACCTCT TCGCTGCCTC TCACATCTTC CGAGAACGCG CACTGAGGCG CAGGTCCTGT 1620

GTCCCTTTTC AGGAGTCCAG CATCTCTAGC TTCACGGACC CACTGTGGCC CCACACAGCC 1680

ATGCTGTTAG GCCAGGCAGT GAGGCGAAGC CGCAAGCTCG GTTATGGTAG TCGCCGGTGG 1740

GGGCGGAGGT TGCCAAGCAG ATCCAGGGAG CTGCTAGGCC TGTTACCATC TGGCCCCCTG 1800

CTGCCCCACA TGCAGCGCTA CTCCAACCGG AAATCCGGAG TGGCAGTGCC TCAACTGCCC 1860

CATGATGCCA CCATCTGA 1878

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++ + p+f    + +d+   aff+v+DGhgg ++a +++++lh  l

Q: 148   SIHAIKNMRRKMEDKHVIIPDFNTLFNIQDQeeQAFFAVFDGHGGVDAAIYAANHLHVNL  207

         567899***************9876655554558**************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++ +     +++ ++al +aF+ tde++  ++++s ++ ++G+t vv  +++ +lyva

Q: 208   VRQES----FSQDPSEALCRAFKVTDERF--VKKASRENLRCGTTGVVTFLRGRTLYVAW  261

         ***77....6788888999**********..8888889999*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         +GdS+++L r g++vel + Hkp+redE++Rie+ gg vi   g  Rv+G+L vsRa+Gd

Q: 262   LGDSQVILVRRGQVVELMKPHKPDREDEKQRIEALGGCVIWF-GTwRVNGSLSVSRAIGD  320

         ****************************************66.777**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  +++l+ ++++liLa+DG wd+v++ eav++v d+l+ ++ +++ +a

Q: 321   SEHKPYICGDADHGVFPLDGSEDYLILACDGFWDTVNPDEAVRVVSDHLQeNTGDTTMVA  380

         ************************************************9955668899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 381   HKLVASARDAGSSDNITVIVV  401

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVIIP DFNTLFNIQD QEEQAFFAVF DGHGGVDAAI YAANHLHVNL 60

VRQESFSQDP SEALCRAFKV TDERFVKKAS RENLRCGTTG VVTFLRGRTL YVAWLGDSQV 120

ILVRRGQVVE LMKPHKPDRE DEKQRIEALG GCVIWFGTWR VNGSLSVSRA IGDSEHKPYI 180

CGDADHGVFP LDGSEDYLIL ACDGFWDTVN PDEAVRVVSD HLQENTGDTT MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>