EKS-ORN-00301

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00301

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	419.2	8.0E-126	67	328	262

Status

Unreviewed

Ensembl Protein

ENSONIP00000023959

UniProt Accession

I3KS63;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000019029	ENSONIP00000023959	ENSONIT00000023980

Organism

Oreochromis niloticus

Functional Description

Protein Length

417

Protein Sequence
(FASTA)

CLSQGQEEAD TSDEDQAKEE QSVNPITAQH GTATNSDSNL GSGLTDLQPP AYFKLEFRRN 60

AVTDDYKITS QVLGLGINGK VLECYCKKTG EKCALKILYD TPKARREVEL HWRASGGPHI 120

VRILSLYENM HHGKKCLLIV MECMEGGELF SRIQARGDQA FTEREVSEIM HDIGMAIEYL 180

HHMDIAHRDV KPENLLYTTK ESNATLKLTD FGFAKEMTLH NSLQTPCYTP YYVAPEVLGP 240

EKYDKSCDMW SLGVIMYILL CGFPPFYSNT SQAISPGMKQ RIRLGQYEFP NPEWADVSEE 300

AKQLIIQLLK TDPSERMTIG QFMNHPWISQ SMVVPQTPLY TSQVLTEDKE LWEDVKEEMT 360

SALATMRVDY DQVKIKDLDT SNNPLLKRRK RPVPPGADGV EEADRGDGDG SGVCNSQ 417

Nucleotide Sequence
(FASTA)

TGTTTGAGCC AAGGCCAAGA AGAGGCAGAT ACCAGTGATG AGGACCAGGC AAAGGAGGAG 60

CAGTCGGTAA ATCCTATTAC CGCGCAGCAC GGGACAGCGA CCAACAGCGA CTCCAACTTG 120

GGCAGCGGCC TGACTGACCT CCAGCCACCT GCTTACTTCA AACTGGAGTT CAGGAGAAAC 180

GCGGTGACCG ATGACTACAA AATAACATCT CAGGTCCTTG GCCTGGGAAT CAATGGCAAA 240

GTACTGGAGT GTTACTGCAA GAAAACAGGA GAGAAATGTG CGCTCAAGAT TCTCTACGAC 300

ACTCCCAAAG CCCGACGGGA GGTCGAGCTG CACTGGCGAG CGTCCGGAGG TCCCCACATC 360

GTACGGATAC TCAGCCTCTA TGAGAACATG CACCATGGGA AGAAATGTCT CCTCATTGTT 420

ATGGAATGCA TGGAGGGAGG GGAACTGTTC AGTCGCATTC AGGCCAGAGG GGACCAGGCT 480

TTCACAGAGA GAGAGGTGTC GGAGATCATG CATGACATTG GCATGGCCAT AGAATACCTC 540

CACCACATGG ACATTGCTCA CAGAGATGTA AAGCCTGAAA ACTTGCTCTA CACAACTAAA 600

GAGAGCAACG CTACTCTAAA GCTGACTGAC TTTGGCTTTG CTAAGGAGAT GACGCTGCAC 660

AACTCCCTGC AAACTCCGTG TTACACTCCG TATTATGTTG CGCCAGAAGT GCTTGGGCCA 720

GAGAAATACG ACAAATCATG TGACATGTGG TCTTTGGGTG TAATCATGTA CATCCTACTC 780

TGTGGGTTTC CTCCATTCTA CTCAAACACA AGCCAGGCCA TCTCTCCAGG CATGAAACAG 840

AGGATCAGGT TGGGCCAATA TGAGTTTCCG AACCCAGAGT GGGCAGACGT TTCTGAGGAA 900

GCCAAACAGC TCATCATTCA GTTACTGAAG ACAGACCCCA GCGAGAGGAT GACGATTGGA 960

CAGTTCATGA ACCATCCTTG GATTAGTCAA TCCATGGTGG TCCCTCAAAC ACCTTTGTAC 1020

ACCTCTCAGG TTTTGACAGA GGACAAGGAA CTATGGGAAG ATGTAAAGGA GGAAATGACC 1080

AGTGCCCTGG CCACGATGCG CGTCGACTAC GACCAGGTGA AGATCAAAGA CTTGGATACA 1140

TCCAACAACC CTCTGCTGAA GAGACGCAAG AGGCCCGTTC CTCCGGGAGC TGACGGCGTA 1200

GAGGAAGCTG ACAGAGGGGA TGGAGATGGA TCAGGAGTGT GTAACAGTCA G 1251

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         k+t++vlG Gi+gkvlec+ kktgek+alkil+d++k+rrevelh++asg ++iv+++ +

Q: 67    KITSQVLGLGINGKVLECYCKKTGEKCALKILYDTPKARREVELHWRASGGPHIVRILSL  126

         5799********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++k+ll+v+e++eGGel+sriq r  +afte+e+se+++di++a+++lh+++ia

Q: 127   YENMHHGKKCLLIVMECMEGGELFSRIQARgdQAFTEREVSEIMHDIGMAIEYLHHMDIA  186

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy++ke+na++kl+Dfg+ake++ +++l+tpc+t++yvaPevl++ek

Q: 187   HRDVKPENLLYTTKESNATLKLTDFGFAKEMTLHNSLQTPCYTPYYVAPEVLGPEK----  242

         ********************************************************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++++ais+++k+ri+ g+yefP++eW++vseea

Q: 243   -YDKSCDMWSLGVIMYILLCGFPPFYSNTSQAISPGMKQRIRLGQYEFPNPEWADVSEEA  301

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+li +lLk+dp+er+ti +++nhpw+

Q: 302   KQLIIQLLKTDPSERMTIGQFMNHPWI  328

         **************************8

Domain Sequence
(FASTA)

KITSQVLGLG INGKVLECYC KKTGEKCALK ILYDTPKARR EVELHWRASG GPHIVRILSL 60

YENMHHGKKC LLIVMECMEG GELFSRIQAR GDQAFTEREV SEIMHDIGMA IEYLHHMDIA 120

HRDVKPENLL YTTKESNATL KLTDFGFAKE MTLHNSLQTP CYTPYYVAPE VLGPEKYDKS 180

CDMWSLGVIM YILLCGFPPF YSNTSQAISP GMKQRIRLGQ YEFPNPEWAD VSEEAKQLII 240

QLLKTDPSER MTIGQFMNHP WI 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013