EKS-ORN-00579

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00579

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	447.4	2.5E-134	25	309	285

Status

Unreviewed

Ensembl Protein

ENSONIP00000024356

UniProt Accession

I3KTA9;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK14 (1 of 2)

Gene Synonyms/Alias

MAPK14 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000019351	ENSONIP00000024356	ENSONIT00000024377
ENSONIG00000019351	ENSONIP00000024355	ENSONIT00000024376

Organism

Oreochromis niloticus

Functional Description

Protein Length

361

Protein Sequence
(FASTA)

MSQKERPTFY RQELNKTVWE VPERYQNLSP VGSGAYGSVC SAFDVKTNLK VAVKKLSRPF 60

QSIIHAKRTY RELRLLKHMK HENVIGLLDV FTPATSLEEF NDVYLVTHLM GADLNNIVKC 120

QKLTDDHVQF LIYQILRGLK YIHSADIIHR DLKPSNLAVN EDCELKILDF GLARHTDDEM 180

TGYVATRWYR APEIMLNWMH YNMTVDIWSV GCIMAELLTG RTLFPGTDHI NQLQQIMRLT 240

GTPPASLISR MPSHEARNYI NSLPQMPKRN FADVFIGANP LAVDLLEKML VLDTDKRITA 300

SEALAHPYFA QYHDPDDEPE AEPYDQSFES RELEIEEWKT LTYEEVISFV PPSFDEDDME 360

S 361

Nucleotide Sequence
(FASTA)

ATGTCGCAGA AGGAGAGACC CACGTTTTAC CGACAGGAGC TCAACAAAAC CGTGTGGGAA 60

GTCCCGGAGC GCTACCAGAA CTTATCTCCT GTCGGTTCCG GTGCTTACGG ATCCGTGTGC 120

TCGGCGTTTG ATGTGAAGAC GAACCTGAAG GTAGCAGTGA AGAAGTTGTC CAGACCTTTC 180

CAGTCCATCA TCCATGCAAA GAGAACCTAC AGAGAGCTGC GGCTGCTCAA ACACATGAAG 240

CATGAAAATG TGATCGGCCT TTTAGATGTT TTCACACCAG CGACAAGCTT AGAGGAATTT 300

AACGATGTGT ACTTGGTGAC ACACCTAATG GGGGCAGACC TCAACAACAT CGTGAAGTGT 360

CAGAAGCTCA CGGATGACCA CGTCCAGTTC CTCATATACC AGATCCTCAG AGGCTTAAAG 420

TACATCCACT CTGCAGATAT CATCCACAGA GATTTGAAGC CCAGTAATCT GGCTGTGAAT 480

GAAGACTGTG AGCTTAAGAT CCTGGACTTT GGTTTGGCAC GGCACACGGA TGATGAAATG 540

ACAGGATACG TAGCCACACG GTGGTACCGC GCCCCGGAGA TCATGCTCAA CTGGATGCAC 600

TACAACATGA CCGTGGATAT CTGGTCGGTG GGCTGCATCA TGGCTGAACT ACTTACAGGA 660

CGGACGCTCT TCCCTGGCAC AGACCATATA AACCAGCTGC AGCAGATAAT GCGCCTGACA 720

GGGACGCCCC CAGCCTCCCT AATAAGCAGG ATGCCCAGCC ACGAGGCGAG GAACTATATC 780

AACTCACTTC CCCAGATGCC AAAGAGAAAC TTTGCTGACG TGTTTATTGG TGCCAACCCT 840

CTTGCGGTGG ATTTGCTGGA GAAAATGTTG GTGCTGGATA CAGACAAGCG GATCACAGCA 900

TCTGAGGCTC TGGCCCACCC TTACTTTGCC CAGTATCACG ATCCAGATGA CGAGCCTGAA 960

GCAGAGCCTT ACGACCAGAG CTTTGAAAGC CGTGAGCTGG AAATTGAGGA ATGGAAAACC 1020

TTAACCTACG AAGAGGTCAT CAGCTTCGTG CCACCATCTT TCGACGAAGA CGACATGGAA 1080

TCTTGA 1086

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y++l+p+g+Gayg v+sa+d +t+ +va+kklsrpfq+ ++akrt+REl+llk++kheN+

Q: 25    YQNLSPVGSGAYGSVCSAFDVKTNLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENV  84

         899*********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i lldvftp+++lee++dvYlvt+lm++dL++++k qkl+d+h+++l+yqilrglky+Hs

Q: 85    IGLLDVFTPATSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHS  144

         ************************************************************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKPsNl+vnedcelkildFGlar++d+e    +t+yvatrwYraPei+l++++

Q: 145   ADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE----MTGYVATRWYRAPEIMLNWMH  200

         **********************************9....*********************

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         y+ +vDiWsvGCI+aElltg++lfpg+d+i+ql++i++++gtp ++ ++++ s+earnyi

Q: 201   YNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYI  260

         ************************************************************

S: 241   kslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         +slp+++k++f+++f  a++ a+dLlek+Lvld+dkRi+++eaL+hpY+

Q: 261   NSLPQMPKRNFADVFIGANPLAVDLLEKMLVLDTDKRITASEALAHPYF  309

         ************************************************6

Domain Sequence
(FASTA)

YQNLSPVGSG AYGSVCSAFD VKTNLKVAVK KLSRPFQSII HAKRTYRELR LLKHMKHENV 60

IGLLDVFTPA TSLEEFNDVY LVTHLMGADL NNIVKCQKLT DDHVQFLIYQ ILRGLKYIHS 120

ADIIHRDLKP SNLAVNEDCE LKILDFGLAR HTDDEMTGYV ATRWYRAPEI MLNWMHYNMT 180

VDIWSVGCIM AELLTGRTLF PGTDHINQLQ QIMRLTGTPP ASLISRMPSH EARNYINSLP 240

QMPKRNFADV FIGANPLAVD LLEKMLVLDT DKRITASEAL AHPYF 285

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>