EKS-ORN-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORN-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	485.8	4.3E-146	24	291	268

Status

Unreviewed

Ensembl Protein

ENSONIP00000025128

UniProt Accession

I3KVI2;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSONIG00000019951	ENSONIP00000025128	ENSONIT00000025149

Organism

Oreochromis niloticus

Functional Description

Protein Length

390

Protein Sequence
(FASTA)

MTKDIVVGDE LPDWVGAKEF YQKYDPKEVI GRGVSSVVRR CVHRHTGQEL AVKIIEITAE 60

KMTIQQLEEV KISTLKEIQV LNMVKEHPSI ITLIDSYESA TFIFLVFDLM RRGELFDYLT 120

EKVTLSEKET RSMMRALLEA VQYLHSLNIV HRDLKPENIL LDDYGHIKLS DFGFSVQLQP 180

GEKLRELCGT PGYLAPEILK CSMDEMHPGY GKEVDLWACG VILFTLLAGS PPFWHRKQML 240

MLRMIMEGRY QFSSPEWDDR SDTVKDLISR LLVVDPANRL TAEQALAHCF FRQYQREDVR 300

LFSPRKTFRV LIVSVLACIR MYSRYRRVRP LTREVLARDP YSIRGVRKLI DGCAFRIYGH 360

WVKKGEQQNR AALFQNTAKI MLLELEEFET 390

Nucleotide Sequence
(FASTA)

ATGACCAAAG ACATCGTTGT TGGGGACGAA TTACCAGACT GGGTGGGGGC CAAGGAGTTT 60

TATCAGAAGT ATGATCCTAA AGAGGTGATT GGCAGGGGTG TGAGCAGTGT GGTGCGCAGG 120

TGTGTGCACA GACACACGGG CCAGGAGCTG GCGGTGAAGA TTATCGAGAT CACAGCTGAG 180

AAGATGACAA TCCAGCAGTT GGAGGAGGTG AAAATCTCCA CGCTGAAAGA GATCCAAGTG 240

CTCAACATGG TGAAGGAACA CCCCTCCATC ATCACCCTCA TTGATTCCTA TGAGTCTGCT 300

ACATTCATAT TTTTGGTGTT TGACCTCATG AGACGTGGAG AGCTGTTTGA CTACCTCACA 360

GAAAAAGTTA CCCTAAGTGA GAAGGAAACC AGGAGCATGA TGCGAGCTCT GCTGGAGGCC 420

GTGCAATACC TTCATTCCCT CAACATCGTA CACCGGGATC TGAAACCGGA GAACATTCTC 480

CTGGACGATT ATGGCCATAT CAAACTCTCT GACTTTGGTT TTTCCGTGCA GCTACAACCT 540

GGGGAGAAGC TTCGAGAGCT CTGTGGGACA CCTGGTTATT TGGCGCCCGA AATACTAAAG 600

TGTTCCATGG ATGAAATGCA CCCAGGCTAC GGCAAGGAGG TCGATCTCTG GGCCTGTGGA 660

GTCATCCTCT TCACCTTACT AGCCGGCTCG CCTCCGTTCT GGCACCGTAA GCAGATGCTG 720

ATGCTGAGGA TGATAATGGA GGGTCGCTAT CAGTTCAGTT CCCCAGAGTG GGACGACCGG 780

TCTGACACTG TGAAGGATCT GATATCCAGG CTGCTGGTGG TGGACCCAGC TAACCGTCTC 840

ACTGCTGAGC AAGCCTTGGC GCATTGCTTC TTCAGGCAGT ACCAGCGGGA GGATGTGAGG 900

CTCTTCAGCC CCAGAAAGAC GTTTAGGGTT CTGATAGTGA GCGTGCTCGC CTGCATCAGG 960

ATGTACAGCC GCTACCGCAG GGTGCGGCCG CTAACGCGGG AGGTGCTGGC GAGGGATCCT 1020

TACTCCATCC GCGGCGTGCG CAAGCTCATC GACGGCTGCG CTTTCCGGAT CTACGGGCAC 1080

TGGGTCAAGA AAGGGGAGCA GCAGAACCGA GCAGCCCTCT TTCAGAACAC TGCTAAGATC 1140

ATGCTGCTAG AGCTGGAGGA GTTTGAAACA TAA 1173

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pke++GrGvssvvrrc++++tgqe avkii+++aek++ ++++e++ +tlke+++l+

Q: 24    YDPKEVIGRGVSSVVRRCVHRHTGQELAVKIIEITAEKMTIQQLEEVKISTLKEIQVLNM  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v  hpsii+l+d+yes +f+flvfdlm++Gelfdyltekvtlseketr++mralleav+y

Q: 84    VKEHPSIITLIDSYESATFIFLVFDLMRRGELFDYLTEKVTLSEKETRSMMRALLEAVQY  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh+ nivhrdlkpenilldd  +iklsdfGfs+ql++GeklrelcGtpgylapeilkcsm

Q: 144   LHSLNIVHRDLKPENILLDDYGHIKLSDFGFSVQLQPGEKLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de +pGy+kevdlwa+Gvil+tllaGsppfwhrkq+lmlr+imeG+yqf+spewdd+s++

Q: 204   DEMHPGYGKEVDLWACGVILFTLLAGSPPFWHRKQMLMLRMIMEGRYQFSSPEWDDRSDT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+llvvdp +rltae+alah ff

Q: 264   VKDLISRLLVVDPANRLTAEQALAHCFF  291

         **************************98

Domain Sequence
(FASTA)

YDPKEVIGRG VSSVVRRCVH RHTGQELAVK IIEITAEKMT IQQLEEVKIS TLKEIQVLNM 60

VKEHPSIITL IDSYESATFI FLVFDLMRRG ELFDYLTEKV TLSEKETRSM MRALLEAVQY 120

LHSLNIVHRD LKPENILLDD YGHIKLSDFG FSVQLQPGEK LRELCGTPGY LAPEILKCSM 180

DEMHPGYGKE VDLWACGVIL FTLLAGSPPF WHRKQMLMLR MIMEGRYQFS SPEWDDRSDT 240

VKDLISRLLV VDPANRLTAE QALAHCFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013