EKS-OCP-00046

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00046

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	331.4	3.3E-99	23	334	312

Status

Unreviewed

Ensembl Protein

ENSOPRP00000001395

Gene Name

CDK8

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000001510	ENSOPRP00000001395	ENSOPRT00000001513

Organism

Ochotona princeps

Protein Length

463

Protein Sequence
(FASTA)

IDYDFNIKIS NERERVEDLF LYKSGKIGRG TLGRVFTKRE EKKDDKDYAL KQIEGTGISM 60

SACREIALLR ELKHPNVISL QKVFLSHADR KVWLLFDYAE HDLWHIIKFH RASKANKKPV 120

QLPRGMVKSL LYQILDGIHY LHANWVLHRD LKPANILVMG EGPERGRVKI ADMGFARLFN 180

SPLKPLADLD PVVVTFWYRA PELLLGARHY TKAIDIWAIG CIFAELLTSE PIFHCRQEDI 240

KTSNPYHHDQ LDRIFNVMGF PADKDWEDIK KMPEHSTLMK DFRRNTYTNC SLIKYMEKHK 300

VKPDSKAFHL LQKLLTMDPI KRITSEQAMQ DPYFLEDPLP TSDVFAGCQI PYPKREFLTE 360

EEPDDKGDKK NQQQQQGNNH TNGTGHPGNQ ESSHTQGPPL KKVRVVPPTT TSGGLIMTSD 420

YQRSNPHAAY PNPGPSTSQP QSSMGYSATS QQPPQYSHQT HRY 463

Nucleotide Sequence
(FASTA)

ATAGACTATG ACTTTAATAT AAAGATAAGC AACGAGCGGG AGCGGGTCGA GGACCTTTTT 60

TTATACAAGA GCGGCAAAAT AGGTCGAGGC ACTCTCGGTC GCGTCTTCAC CAAGAGAGAA 120

GAAAAGAAGG ATGATAAAGA CTACGCTTTA AAACAAATAG AAGGAACTGG GATCTCTATG 180

TCAGCATGCA GAGAAATAGC GTTACTTCGA GAGTTAAAGC ATCCGAATGT CATCTCTCTT 240

CAAAAGGTGT TTTTGTCTCA TGCTGATAGG AAAGTATGGC TTCTGTTTGA CTATGCCGAA 300

CATGATCTCT GGCATATAAT CAAGTTTCAC AGAGCTTCAA AAGCAAACAA GAAGCCAGTT 360

CAATTACCTC GGGGAATGGT GAAGTCACTG TTATATCAGA TCCTAGATGG CATTCATTAC 420

CTGCATGCTA ACTGGGTGTT GCACAGGGAT TTGAAACCTG CTAATATTTT AGTTATGGGT 480

GAAGGTCCTG AGCGAGGAAG AGTAAAAATT GCTGATATGG GCTTTGCCCG TTTATTTAAT 540

TCACCTTTGA AGCCTTTAGC AGATTTGGAT CCAGTGGTTG TAACATTCTG GTATCGTGCC 600

CCAGAACTGC TTCTTGGAGC AAGACATTAT ACCAAAGCTA TTGATATTTG GGCTATAGGG 660

TGTATATTTG CAGAACTACT AACGTCAGAA CCAATATTTC ACTGTCGACA AGAGGACATC 720

AAAACTAGTA ACCCTTACCA CCATGACCAG CTGGACAGAA TATTCAATGT AATGGGATTC 780

CCTGCAGATA AAGATTGGGA AGATATAAAA AAGATGCCTG AACATTCAAC ATTAATGAAA 840

GATTTCAGAA GAAATACGTA TACCAACTGC AGCCTTATCA AGTATATGGA GAAACATAAA 900

GTTAAACCAG ATAGTAAAGC ATTCCACTTG CTTCAAAAAT TGCTTACTAT GGACCCAATA 960

AAGCGAATTA CCTCAGAACA GGCTATGCAG GATCCCTATT TTCTGGAAGA CCCACTTCCT 1020

ACATCAGATG TTTTTGCTGG TTGTCAAATC CCTTACCCCA AACGAGAATT TTTAACAGAA 1080

GAAGAACCTG ATGACAAAGG CGACAAAAAG AACCAGCAGC AGCAGCAGGG CAATAACCAC 1140

ACCAACGGAA CGGGCCACCC AGGGAACCAG GAGAGCAGTC ACACACAGGG ACCCCCTCTG 1200

AAAAAAGTGA GAGTTGTTCC TCCTACCACT ACCTCAGGCG GACTCATCAT GACCTCAGAC 1260

TATCAGCGTT CCAATCCACA TGCTGCCTAT CCCAACCCTG GACCAAGCAC ATCACAGCCC 1320

CAGAGCAGCA TGGGGTACTC AGCTACCTCC CAGCAGCCTC CACAGTACTC ACATCAGACA 1380

CATCGGTACT GA 1392

Domain Profile

S: 3     klekigeGtygkvykakd.ketgevvAlKkirlekekegvpitalrEisllkelkhkniv  61

         k  kig+Gt g v+  ++ k++++ +AlK+i    e +g++++a+rEi+ll+elkh+n++

Q: 23    KSGKIGRGTLGRVFTKREeKKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVI  78

         5679*********988875888899******....999**********************

S: 62    kLlevva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqllegl  113

         +L++v+  ++++k++L+f+++e+dL++++k ++++       +l++ +vksll+q+l+g+

Q: 79    SLQKVFLsHADRKVWLLFDYAEHDLWHIIKFHRASkankkpvQLPRGMVKSLLYQILDGI  138

         ******94555*********************9999999999******************

S: 114   aylHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwY  166

         +ylH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wY

Q: 139   HYLHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWY  198

         *********************9988889*************99999665699********

S: 167   raPelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkll  217

         raPelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++

Q: 199   RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpyhHDQLDRIFNVM  258

         ************************************************************

S: 218   gtpsekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllald  268

         g p +k+w++++k+pe++   k+f++++++  +l ++++k k    +ka++ll+kll++d

Q: 259   GFPADKDWEDIKKMPEHStlmKDFRRNTYTncSLIKYMEKHKvkpdSKAFHLLQKLLTMD  318

         *****************96644777777764455666644333354679***********

S: 269   pkkRisakealqhkyf  284

         p kRi++++a+q++yf

Q: 319   PIKRITSEQAMQDPYF  334

         ***************9

Domain Sequence
(FASTA)

KSGKIGRGTL GRVFTKREEK KDDKDYALKQ IEGTGISMSA CREIALLREL KHPNVISLQK 60

VFLSHADRKV WLLFDYAEHD LWHIIKFHRA SKANKKPVQL PRGMVKSLLY QILDGIHYLH 120

ANWVLHRDLK PANILVMGEG PERGRVKIAD MGFARLFNSP LKPLADLDPV VVTFWYRAPE 180

LLLGARHYTK AIDIWAIGCI FAELLTSEPI FHCRQEDIKT SNPYHHDQLD RIFNVMGFPA 240

DKDWEDIKKM PEHSTLMKDF RRNTYTNCSL IKYMEKHKVK PDSKAFHLLQ KLLTMDPIKR 300

ITSEQAMQDP YF 312

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>