EKS-OCP-00048

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00048

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/EGFR	453.6	1.4E-136	707	963	257

Status

Unreviewed

Ensembl Protein

ENSOPRP00000005278

Gene Name

ERBB3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000005724	ENSOPRP00000005278	ENSOPRT00000005749

Organism

Ochotona princeps

Protein Length

1338

Protein Sequence
(FASTA)

MRASSALQVL GVLLSLARGS DVGNSQAVCT GTLNGLSVTG DAENQYQTLY KLYNKCEVVM 60

GNLEIVLTGH NSDLSFLQWI REVTGYVLVA MNEFSTLPLP NLRVVRGTQF YDGKFAIFVM 120

LNYNTNSSHA LRQLRFTQLT EILSGGVYIE KNDKLCHMDT IDWRDIVRDP AAEIAVKDNG 180

RSCPPCHEAC KGRCWGPGPE DCQTLTKTIC APQCNGHCFG PDPNQCCHDE CAGGCSGPQD 240

TDCFACRHFN DSGACVPRCP QPLVYNKLTF QLESNPHTKY QYGGVCVVSC PHNFVVDQTS 300

CVRACPPDKM EVDKNGLKIC EPCGGLCPKA CEGTGSGSRF QTVDSSNIDG FVNCTKILGN 360

LDFLITGLNG DPWHKIPALD PEKLNVFGTV REITGYLNIQ SWPPHMHNFS VFSNLTTIGG 420

RSLYNRGFSL LIMKNLNVTS LGFRSLKEIS AGRIYISANR QLCYHHSLNW TRLLRGPADE 480

RLDIKHNRPR RECVAEGKVC DSLCSPGGCW GPGPGQCLSC RNYSRGGACV THCNFLNGEP 540

REFAHEGECF SCHQECQLME GAATCNGSGS DACAQCAHFR DGPHCVSSCP NGVLGAKGPI 600

YKYPDAHNEC RPCHENCTQG CKGPELQDCL GQPLVLISKT HLAMAVTVGL AAVFLILGGT 660

FLYWRGRRIQ NKRAMRRYLE RGESIEPLDP SEKANKVLAR IFKETELRKL KVLGAGVFGT 720

VHKGVWIPEG ESIKIPVCIK VIEDKSGRQS FQAVTDHMLA IGSLDHAHIV RLLGLCPGSS 780

LQLVTQYLPL GSLLDHVRQQ RESLGPQLLL NWGVQIAKGM YYLEEHGMVH RNLAARNVLL 840

KSPSQVQVAD FGVADLLPPD DKQLLHSEAK TPIKWMALES IHFGKYTHQS DVWSYGVTVW 900

ELMTFGAEPY AGLRLAEVPD LLEKGERLAQ PQICTIDVYM VMVKCWMIDE NIRPTFKELA 960

NEFTRMARDP PRYLVIKRES GPGLAQGAEP STLTDKELEE VELEPELDLD LDLEAEDDSL 1020

ATTLGSALNL PSGTLPRPRG SQSLLSPSSG YMPMNQSNLG EACQESAGCG ASDRCPRPVS 1080

LHPLPRTRLI SESSDGHVTG SEAEFPEKGS MCRSRSRSRS PRPRGDSAYH SQRHSLLTPV 1140

TPVAPPGLEE EDVNGYVMPD THPKGPPSSR EGTLSSVGLS SVLGTEEEDE DEEYEYMNRR 1200

RRPSSSRPPR PSSLEELGYE YMDVGSDLSA SLGSTQSCPL NPVPIVPAAG TTPDEDYEYM 1260

NRRRGGGPGG DYAAMEACPA AEQGYEEMRA FQGPGQQAPH VRYARLKTLR SLEATDSAFD 1320

NPDYWHSRLF PKANAQRT 1338

Nucleotide Sequence
(FASTA)

ATGCGGGCCA GCTCGGCTCT GCAGGTGCTG GGCGTCCTTC TCAGTCTGGC CCGGGGCTCG 60

GACGTGGGCA ACTCGCAGGC AGTGTGTACT GGGACTCTGA ATGGACTGAG TGTGACCGGC 120

GATGCTGAGA ACCAATACCA GACACTGTAC AAGCTCTACA ACAAGTGCGA GGTGGTGATG 180

GGGAACCTGG AGATAGTGCT CACCGGCCAC AACTCTGATC TCTCCTTCCT GCAGTGGATC 240

CGAGAAGTGA CAGGCTATGT CCTCGTGGCC ATGAATGAGT TCTCTACGCT ACCGTTGCCC 300

AACCTTCGAG TGGTGCGTGG AACCCAGTTC TACGACGGGA AGTTTGCCAT CTTCGTCATG 360

TTGAACTACA ACACCAACTC CAGCCATGCT CTGCGCCAGC TCCGCTTCAC TCAGCTCACT 420

GAGATTCTGT CAGGGGGCGT TTATATCGAG AAGAATGATA AACTTTGTCA CATGGACACA 480

ATTGACTGGA GGGACATCGT GAGGGACCCA GCTGCTGAGA TAGCGGTGAA GGACAATGGC 540

AGAAGCTGTC CTCCCTGCCA TGAGGCCTGC AAGGGAAGAT GCTGGGGTCC TGGACCTGAA 600

GACTGCCAAA CATTGACCAA GACCATCTGT GCCCCTCAAT GTAATGGTCA CTGCTTTGGG 660

CCCGACCCTA ACCAGTGCTG CCATGATGAG TGTGCTGGGG GCTGTTCAGG CCCTCAGGAC 720

ACGGACTGCT TCGCCTGCAG ACACTTCAAT GACAGTGGAG CCTGTGTGCC CCGGTGTCCA 780

CAACCATTGG TCTACAATAA GCTGACTTTC CAGCTGGAGT CCAACCCTCA CACCAAGTAT 840

CAGTATGGAG GAGTTTGTGT AGTCAGCTGT CCCCATAACT TTGTGGTGGA TCAAACTTCC 900

TGCGTCAGGG CCTGTCCTCC TGACAAGATG GAAGTGGACA AAAATGGGCT CAAGATATGC 960

GAGCCTTGTG GGGGCCTGTG TCCCAAAGCC TGCGAGGGCA CGGGCTCTGG CAGTCGTTTC 1020

CAGACTGTTG ACTCGAGCAA CATCGATGGA TTTGTGAACT GCACCAAGAT CCTGGGCAAT 1080

CTGGATTTTC TCATCACCGG CCTCAATGGA GATCCATGGC ACAAGATCCC CGCACTGGAC 1140

CCAGAGAAGC TCAATGTCTT CGGAACAGTT AGGGAGATCA CGGGCTACCT GAACATCCAG 1200

TCGTGGCCTC CGCACATGCA CAACTTTAGT GTTTTCTCCA ACCTGACGAC CATTGGGGGC 1260

AGAAGCCTCT ACAACCGGGG CTTCTCATTA TTGATCATGA AGAACTTGAA CGTGACGTCT 1320

CTGGGTTTCC GATCTCTGAA GGAGATCAGT GCTGGGCGTA TCTATATAAG TGCCAATCGT 1380

CAGCTGTGCT ACCATCACTC TCTGAACTGG ACCAGGCTGC TGCGGGGGCC AGCAGATGAG 1440

AGGCTTGACA TCAAACACAA CCGGCCGCGT AGAGAGTGTG TGGCTGAGGG CAAAGTGTGT 1500

GACTCTCTGT GCTCCCCCGG GGGCTGCTGG GGTCCAGGCC CTGGTCAGTG TCTGTCCTGT 1560

CGAAACTACA GCCGAGGAGG TGCCTGCGTG ACCCACTGCA ACTTTCTGAA TGGGGAGCCT 1620

CGAGAGTTTG CCCACGAGGG TGAGTGCTTC TCCTGCCACC AGGAATGCCA GCTCATGGAG 1680

GGCGCTGCTA CGTGCAATGG CTCAGGCTCT GATGCTTGTG CCCAGTGTGC CCATTTCCGA 1740

GATGGGCCCC ACTGTGTGAG CAGCTGTCCC AACGGAGTGC TAGGTGCCAA GGGCCCCATC 1800

TACAAGTATC CTGATGCTCA CAATGAATGC CGGCCCTGCC ACGAGAACTG CACGCAGGGG 1860

TGTAAGGGAC CAGAACTACA AGACTGTTTA GGCCAACCTC TGGTGCTGAT CAGCAAAACC 1920

CATCTGGCAA TGGCTGTGAC AGTAGGATTG GCAGCGGTCT TCCTGATCCT GGGGGGCACT 1980

TTTCTCTACT GGCGTGGGCG CCGAATTCAG AATAAAAGGG CTATGAGGCG CTACCTGGAA 2040

CGTGGAGAGA GCATAGAGCC TCTGGATCCC AGTGAGAAGG CTAACAAAGT CTTGGCCAGA 2100

ATCTTCAAAG AGACAGAGCT GAGGAAGCTC AAGGTGCTTG GTGCTGGCGT CTTTGGAACT 2160

GTGCACAAAG GCGTATGGAT CCCTGAGGGT GAGTCCATCA AGATTCCAGT CTGCATTAAA 2220

GTCATCGAGG ACAAGAGTGG ACGGCAAAGT TTTCAAGCTG TGACAGATCA CATGCTGGCC 2280

ATCGGCAGCC TGGACCATGC CCACATCGTC CGGCTGCTAG GATTGTGCCC GGGGTCATCT 2340

CTGCAGCTTG TCACTCAGTA CTTGCCTCTG GGCTCCCTAC TGGATCACGT GAGGCAGCAG 2400

AGGGAGTCGC TGGGCCCACA GCTGCTGCTC AATTGGGGAG TGCAGATTGC CAAGGGCATG 2460

TACTATCTTG AGGAACATGG GATGGTGCAT AGAAACCTGG CTGCCCGCAA TGTGCTACTC 2520

AAGTCACCCA GTCAGGTTCA GGTGGCAGAT TTCGGGGTGG CAGACCTGCT GCCCCCAGAT 2580

GACAAGCAAC TTCTCCACAG TGAAGCCAAG ACACCAATTA AGTGGATGGC TCTTGAGAGC 2640

ATCCACTTTG GGAAATACAC ACACCAGAGT GATGTCTGGA GCTATGGTGT AACTGTTTGG 2700

GAGCTGATGA CATTTGGTGC AGAGCCCTAT GCAGGGCTGC GGTTAGCGGA AGTACCAGAC 2760

CTGCTGGAGA AGGGGGAACG GTTGGCACAG CCCCAGATCT GCACCATTGA TGTCTACATG 2820

GTCATGGTCA AGTGTTGGAT GATTGATGAG AATATTCGTC CCACCTTTAA AGAACTGGCC 2880

AATGAGTTCA CCAGGATGGC CCGAGACCCA CCACGGTATC TGGTGATAAA GAGGGAGAGC 2940

GGGCCTGGAC TAGCCCAAGG GGCAGAGCCC TCCACTCTGA CAGACAAGGA ACTGGAGGAA 3000

GTGGAGCTGG AGCCAGAATT GGACCTGGAC CTGGACTTGG AGGCCGAAGA CGACAGCCTA 3060

GCAACCACTC TAGGCTCTGC TCTCAACCTG CCATCTGGAA CACTCCCTCG ACCCCGTGGG 3120

AGCCAGAGCC TCTTGAGTCC ATCATCTGGA TACATGCCCA TGAACCAGAG TAATCTCGGA 3180

GAGGCCTGCC AGGAGTCTGC AGGCTGTGGT GCTAGTGACC GGTGCCCCCG TCCAGTTTCT 3240

CTACACCCAC TGCCACGGAC TCGCCTGATC TCAGAATCTT CGGACGGTCA CGTGACAGGC 3300

TCTGAGGCCG AGTTCCCGGA GAAGGGGTCG ATGTGTCGGA GCCGGAGCCG GAGCCGCAGC 3360

CCCCGGCCCC GGGGAGACAG TGCCTACCAT TCCCAGCGCC ACAGCCTGCT CACGCCTGTC 3420

ACACCTGTGG CCCCACCGGG ACTAGAGGAA GAGGATGTCA ATGGTTATGT CATGCCAGAT 3480

ACACACCCCA AAGGTCCGCC TTCTTCCCGG GAAGGTACTC TTTCTTCAGT GGGTCTCAGT 3540

TCTGTCCTGG GTACTGAAGA GGAAGATGAA GATGAGGAGT ATGAATACAT GAATCGGCGG 3600

CGAAGGCCCA GCTCATCCCG TCCTCCTCGG CCCAGTTCCC TTGAGGAGCT GGGCTATGAG 3660

TACATGGACG TGGGTTCAGA CCTTAGTGCC TCTCTGGGCA GCACACAGAG CTGTCCGCTC 3720

AACCCTGTGC CCATTGTGCC CGCTGCTGGC ACGACTCCGG ATGAGGACTA CGAGTATATG 3780

AATCGACGAC GTGGAGGTGG GCCAGGGGGG GATTATGCAG CTATGGAGGC CTGCCCAGCA 3840

GCTGAGCAAG GGTACGAAGA GATGAGAGCT TTCCAGGGAC CTGGTCAGCA GGCCCCCCAC 3900

GTCCGTTATG CCCGCCTGAA AACACTCCGA AGTCTAGAGG CCACCGACTC CGCCTTTGAT 3960

AACCCTGATT ACTGGCATAG CAGGCTCTTC CCCAAGGCCA ATGCCCAGAG AACCTAG 4017

Domain Profile

S: 1     lkklkvlGsGafGtvykGiwipegenvkipvaikvleektgkkankelldealvlasldh  60

         l+klkvlG+G+fGtv+kG+wipege++kipv+ikv+e+k+g++++++++d++l+++sldh

Q: 707   LRKLKVLGAGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDH  766

         69**********************************************************

S: 61    anlvrllglclsstlqlvtqllplGclldyvrehkdklGsqellnwcvqiakGmsyleek  120

         a++vrllglc  s+lqlvtq+lplG+lld+vr+++++lG+q llnw+vqiakGm+ylee+

Q: 767   AHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQQRESLGPQLLLNWGVQIAKGMYYLEEH  826

         ************************************************************

S: 121   rlvhrdlaarnvlvkspnhvkitdfGlaklleadekelkaeggkvpikwlalesilkrky  180

          +vhr+laarnvl+ksp++v+++dfG+a+ll  d+k+l ++++k+pikw+alesi++ ky

Q: 827   GMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKY  886

         ************************************************************

S: 181   thqsdvwsyGvtvwelltfGakpydgipakeipdllekGerlaqppictidvymvlvkcw  240

         thqsdvwsyGvtvwel+tfGa+py+g++++e+pdllekGerlaqp+ictidvymv+vkcw

Q: 887   THQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCW  946

         ************************************************************

S: 241   midaesrpkfkelaeef  257

         mid+++rp+fkela+ef

Q: 947   MIDENIRPTFKELANEF  963

         ****************9

Domain Sequence
(FASTA)

LRKLKVLGAG VFGTVHKGVW IPEGESIKIP VCIKVIEDKS GRQSFQAVTD HMLAIGSLDH 60

AHIVRLLGLC PGSSLQLVTQ YLPLGSLLDH VRQQRESLGP QLLLNWGVQI AKGMYYLEEH 120

GMVHRNLAAR NVLLKSPSQV QVADFGVADL LPPDDKQLLH SEAKTPIKWM ALESIHFGKY 180

THQSDVWSYG VTVWELMTFG AEPYAGLRLA EVPDLLEKGE RLAQPQICTI DVYMVMVKCW 240

MIDENIRPTF KELANEF 257

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>