EKS-OCP-00045

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00045

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	337.2	5.4E-101	6	295	290

Status

Unreviewed

Ensembl Protein

ENSOPRP00000006069

Gene Name

CDK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000006631	ENSOPRP00000006069	ENSOPRT00000006626

Organism

Ochotona princeps

Protein Length

304

Protein Sequence
(FASTA)

MAVSRYEPVA EIGVGAYGTV YKARDPLSGH FVALKSLRVP SEATPGGGLP ISTVREVALL 60

RRLEAFEHPN VVRLMDVCAT SRTDREIRVT LVFEHVEQDL RAYLNKAPPP GLPVETIKDL 120

MRQFLRGLDF LHSNCIIHRD LKPENILVTN SGTVKLADFG LARIYSYQMA LTPVVVTLWY 180

RAPEVLLQSA YATPVDLWSV GCIFAEMFRR KPLFCGNSEP DQLSKIFDLI GLPPEEDWPR 240

EVSLPRSAFS PQGPRPVQSV VPELEESGAQ LLLEMLTFSP HKRISACKAL QHSYLRKEED 300

NDPE 304

Nucleotide Sequence
(FASTA)

ATGGCTGTCT CTCGATATGA GCCGGTGGCC GAAATTGGCG TGGGGGCCTA TGGGACCGTG 60

TACAAGGCCC GGGATCCTCT CAGTGGCCAC TTTGTGGCCC TGAAGAGCCT GCGTGTCCCC 120

AGTGAAGCGA CGCCGGGAGG GGGCCTTCCC ATCAGCACTG TTCGGGAGGT GGCTTTACTG 180

AGGAGGCTGG AGGCTTTTGA GCATCCCAAT GTTGTCCGGC TGATGGACGT CTGTGCCACC 240

TCTCGAACTG ACCGGGAGAT CAGGGTGACC CTAGTGTTTG AGCACGTGGA GCAGGACTTA 300

AGGGCGTACC TGAATAAGGC ACCTCCACCG GGCTTGCCAG TAGAGACCAT CAAGGATCTG 360

ATGCGGCAGT TTCTGAGAGG CCTGGACTTC CTCCACTCCA ACTGCATCAT TCACCGAGAC 420

TTGAAGCCTG AGAACATCCT GGTGACAAAC AGCGGCACCG TCAAGCTGGC TGACTTTGGC 480

CTGGCCCGAA TCTACAGCTA CCAGATGGCA CTGACACCTG TGGTGGTGAC ACTCTGGTAC 540

CGTGCTCCTG AGGTTCTCCT GCAGTCTGCT TATGCCACGC CTGTGGACCT GTGGAGCGTC 600

GGCTGTATCT TCGCAGAGAT GTTTCGGCGA AAGCCCCTCT TCTGTGGAAA CTCTGAACCT 660

GACCAGTTAA GCAAGATTTT TGACCTGATT GGATTGCCCC CAGAAGAGGA CTGGCCCCGA 720

GAGGTGTCCC TTCCCCGAAG TGCCTTTTCC CCACAAGGGC CCCGCCCGGT GCAGTCAGTG 780

GTGCCTGAGC TGGAGGAGTC CGGAGCACAA CTGCTACTGG AGATGCTGAC TTTCAGCCCA 840

CACAAGCGAA TCTCGGCCTG CAAAGCCCTA CAGCACTCTT ACCTCCGTAA GGAAGAGGAC 900

AACGACCCAG AGTGA 915

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekeke...gvpitalrEisllkel..  55

         ye +++ig G+yg+vyka+d  +g++vAlK++r+ +e +   g+pi+++rE++ll++l

Q: 6     YEPVAEIGVGAYGTVYKARDPLSGHFVALKSLRVPSEATpggGLPISTVREVALLRRLea  65

         88899*******************************996677***************988

S: 56    .khknivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqll  110

          +h+n+v+L++v+a     ++ +++Lvfe++eqdL  +l+k +  +l+ e++k l++q+l

Q: 66    fEHPNVVRLMDVCAtsrtDREIRVTLVFEHVEQDLRAYLNKAPPPGLPVETIKDLMRQFL  125

         89************887444479*************************************

S: 111   eglaylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPe  170

         +gl++lHsn i+HRDlKp+N+L++++g++klaDfGlar +s ++  +t++vvTlwYraPe

Q: 126   RGLDFLHSNCIIHRDLKPENILVTNSGTVKLADFGLARIYSYQMA-LTPVVVTLWYRAPE  184

         ******************************************999.**************

S: 171   lLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsk  230

         +Ll++  Y t vD+Wsvgci+ae+++rkplf g+se dql++if+l+g p e++wp+  +

Q: 185   VLLQS-AYATPVDLWSVGCIFAEMFRRKPLFCGNSEPDQLSKIFDLIGLPPEEDWPREVS  243

         ***88.5*****************************************************

S: 231   lpeykksfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         lp+    f+++ ++ ++++v++l+e++ +ll ++l+++p+kRisa +alqh+y+

Q: 244   LPRSA--FSPQGPRPVQSVVPELEESGAQLLLEMLTFSPHKRISACKALQHSYL  295

         ***65..9999*****************************************96

Domain Sequence
(FASTA)

YEPVAEIGVG AYGTVYKARD PLSGHFVALK SLRVPSEATP GGGLPISTVR EVALLRRLEA 60

FEHPNVVRLM DVCATSRTDR EIRVTLVFEH VEQDLRAYLN KAPPPGLPVE TIKDLMRQFL 120

RGLDFLHSNC IIHRDLKPEN ILVTNSGTVK LADFGLARIY SYQMALTPVV VTLWYRAPEV 180

LLQSAYATPV DLWSVGCIFA EMFRRKPLFC GNSEPDQLSK IFDLIGLPPE EDWPREVSLP 240

RSAFSPQGPR PVQSVVPELE ESGAQLLLEM LTFSPHKRIS ACKALQHSYL 290

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>