EKS-OCP-00083

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00083

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	604.5	5.0E-182	600	958	359

Status

Unreviewed

Ensembl Protein

ENSOPRP00000007561

Gene Name

PDGFRB

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000008257	ENSOPRP00000007561	ENSOPRT00000008265

Organism

Ochotona princeps

Protein Length

1104

Protein Sequence
(FASTA)

MWLPAVMPAP GLKGQSLLLS LLLLLGLQAS QGLVIIPPGP ELVLNISSTF TLTCSGSAPV 60

VWERMSQEPW QEVTVDEDGT FSSMLTLVNV TGVDTGEYFC TYNGSQGLDP SERKRLYVFV 120

PDPTMSFLPT EPEELFIFLT EVTETTIPCR VTDPRLVVTL HEKKEDVPLP IPYDHQRGFS 180

GTFEDKTYVC KTTVGGREVD SDAYYVYSLQ VSSINVSVNA VQTVVRQGEN ITIMCIVTGN 240

EVVNFEWRYP RQESGRLVEP VTDFLFDVPS HIRSILHIPN AETGDSGTYV CNVSESVNDH 300

RDEKAINVTV VESGYVRLLG ELGALQFADL HRSRTLQVVF EAYPPPTVLW FKDNRTLGDS 360

SAGEIALSTR NVSETRYVSE LTLVRVKVAE AGKYTMRAFH EDAEAQLSFQ LQVNVPVRVL 420

ELSESHPASG EQVVRCRGRG MPQPNVTWFT CRDLKRCPSE LPPTPLGNRS EDESQLETNV 480

TYWVEEQEFE VVSTLRLRQV DQPLSVRCML RNLRDYDSKE VTVVPHSLPF KVVVISAILA 540

LVVLTIVSLI ILIMIWQKKP RYEIRWKVIE SVSSDGHEYI YVDPMQLPYD YKWELPRDQL 600

VLGRTLGSGA FGQVVEATAH GLSHSQATMK VAVKMLKSTA RSSEKQALMS ELKIMSHLGP 660

HLNVVNLLGA CTKGGPIYII TEYCRYGDLV DYLHRNKHTF LQHHSDKRRP PSAELYSNAL 720

PIGLRLPSHV SLTGESDGGY MDMSKDESVD YVPMLDMKGD VKYADIESSN YMAPYDNYVP 780

SAPERTYRAT LINESPVLSY TDLVGFSYQV ANGMEFLASK NCVHRDLAAR NVLICEGKLV 840

KICDFGLARD IMRDSNYISK GSTFLPLKWM APESIFNSLY TTLSDVWSFG ILLWEIFTLG 900

GTPYPELPMN EQFYNAIKRG YRMAQPAHAS DEIYEIMQKC WEEKFEIRPP FSQLVLLLER 960

LLGEGYKKKY QQVDEEFLRS DHPAILRSQA RLPGFHGLRS PLDTSSVLYT AVQPNESDND 1020

YIIPLPDTEV ADEGPLEGSP SLASSTLNEV NTSSTISCDS PLEPQEEAEA EPQLESCVES 1080

EPKVEQLLDS GCFGMQAEVE DSFL 1104

Nucleotide Sequence
(FASTA)

ATGTGGCTTC CGGCTGTGAT GCCAGCTCCG GGGCTCAAAG GCCAGTCGCT GCTGCTGTCC 60

CTGCTATTAC TGCTGGGACT TCAGGCCTCC CAGGGCTTGG TCATCATTCC TCCAGGGCCG 120

GAGCTGGTCC TTAACATCTC CAGCACCTTC ACGCTGACCT GCTCGGGTTC CGCTCCAGTG 180

GTGTGGGAAC GTATGTCCCA GGAGCCCTGG CAGGAAGTGA CTGTGGATGA GGACGGCACC 240

TTCTCCAGCA TGCTGACCCT GGTCAACGTC ACTGGGGTGG ACACGGGCGA GTACTTCTGC 300

ACTTACAATG GCTCCCAGGG GCTAGACCCC AGCGAGCGGA AGCGGCTCTA CGTCTTTGTG 360

CCAGATCCCA CCATGAGCTT CCTCCCCACG GAACCCGAGG AGCTGTTCAT TTTCCTCACA 420

GAGGTGACCG AGACCACCAT TCCGTGCCGA GTGACGGACC CACGGCTTGT GGTGACGCTG 480

CACGAGAAGA AGGAGGACGT CCCACTGCCC ATCCCCTATG ACCACCAGCG TGGCTTCTCA 540

GGCACCTTTG AGGACAAGAC CTACGTCTGC AAGACCACCG TCGGGGGCAG GGAAGTGGAC 600

TCGGATGCCT ACTATGTTTA CAGCCTGCAG GTGTCATCCA TAAATGTCTC GGTGAATGCG 660

GTGCAGACTG TGGTCCGCCA GGGTGAGAAC ATCACCATCA TGTGCATTGT GACCGGCAAC 720

GAGGTGGTTA ACTTTGAGTG GCGGTACCCC CGCCAGGAGA GTGGGCGGCT AGTGGAGCCA 780

GTGACTGACT TCCTGTTTGA TGTACCCTCC CACATCCGCT CCATTCTGCA CATCCCCAAT 840

GCTGAGACGG GCGACTCGGG CACCTACGTG TGCAACGTAT CAGAGAGCGT GAACGACCAC 900

CGGGATGAAA AGGCCATCAA TGTCACTGTG GTTGAGAGTG GCTATGTGCG GCTGCTGGGA 960

GAGCTGGGCG CGCTGCAATT CGCTGACCTG CACCGGAGCC GTACACTGCA GGTGGTATTC 1020

GAGGCCTACC CTCCGCCCAC TGTCCTGTGG TTCAAGGACA ACCGCACCCT GGGCGACTCC 1080

AGTGCCGGCG AGATTGCCCT ATCCACACGC AATGTGTCGG AGACCCGGTA TGTGTCAGAG 1140

CTGACACTGG TGCGGGTGAA GGTGGCAGAG GCCGGCAAAT ACACCATGCG TGCTTTCCAC 1200

GAGGACGCCG AGGCCCAGCT CTCCTTCCAA CTGCAGGTCA ATGTCCCTGT GCGTGTGCTG 1260

GAGCTGAGTG AGAGCCATCC CGCCAGTGGG GAGCAGGTAG TCCGCTGTCG CGGCCGAGGC 1320

ATGCCTCAGC CAAACGTTAC CTGGTTCACC TGCAGAGACC TCAAAAGGTG CCCCTCTGAG 1380

CTGCCGCCCA CACCGCTGGG AAACCGCTCA GAGGATGAGA GCCAGCTGGA GACCAACGTG 1440

ACGTACTGGG TGGAAGAGCA GGAGTTTGAG GTGGTGAGCA CGCTGCGCCT GCGCCAGGTG 1500

GACCAGCCCC TGTCTGTGCG CTGCATGCTG CGCAATCTGA GGGACTATGA CAGCAAGGAG 1560

GTCACCGTGG TGCCACACTC TCTGCCCTTC AAAGTGGTGG TGATCTCGGC CATCCTGGCC 1620

TTGGTGGTGC TCACGATCGT CTCCCTCATC ATCCTCATCA TGATCTGGCA GAAGAAGCCA 1680

CGCTACGAGA TCCGGTGGAA AGTGATTGAG TCTGTGAGCT CTGATGGCCA CGAGTACATC 1740

TATGTGGATC CCATGCAGCT GCCCTATGAC TACAAGTGGG AGCTGCCGAG GGACCAGCTT 1800

GTGCTTGGAC GCACCCTCGG CTCTGGGGCC TTCGGGCAGG TCGTGGAAGC CACGGCTCAC 1860

GGCCTGAGTC ATTCGCAGGC CACCATGAAG GTGGCCGTGA AGATGCTGAA ATCCACAGCC 1920

CGGAGCAGTG AAAAGCAAGC CCTCATGTCG GAGCTGAAGA TCATGAGTCA CCTTGGGCCT 1980

CACCTGAATG TGGTCAACCT GCTGGGGGCC TGCACCAAAG GAGGCCCCAT CTACATCATC 2040

ACCGAGTACT GCCGCTACGG CGACCTGGTG GACTACCTGC ACCGGAACAA GCACACTTTC 2100

CTGCAGCACC ACTCCGACAA GCGCCGCCCG CCCAGCGCCG AGCTCTACAG CAATGCCCTG 2160

CCCATTGGCC TGCGCCTGCC CAGTCATGTG TCGTTGACGG GTGAGAGTGA CGGTGGCTAC 2220

ATGGACATGA GTAAGGATGA GTCGGTGGAC TACGTGCCCA TGCTGGACAT GAAAGGAGAC 2280

GTCAAATACG CAGACATCGA ATCTTCCAAC TACATGGCCC CTTATGATAA CTACGTCCCC 2340

TCTGCCCCCG AGAGGACCTA CCGGGCAACT TTGATCAATG AGTCCCCTGT GCTCAGCTAC 2400

ACGGACCTCG TGGGCTTCAG CTACCAGGTG GCCAATGGCA TGGAGTTCCT GGCCTCTAAG 2460

AATTGCGTCC ACCGAGACCT GGCAGCCAGG AACGTGCTCA TCTGTGAGGG CAAGCTAGTC 2520

AAGATCTGTG ACTTTGGCCT GGCTCGAGAC ATCATGCGGG ACTCGAACTA CATCTCCAAA 2580

GGCAGCACCT TCCTGCCTCT GAAATGGATG GCCCCAGAGA GCATCTTCAA CAGCCTCTAC 2640

ACCACGCTGA GTGACGTGTG GTCCTTTGGG ATCCTCCTCT GGGAGATCTT CACCCTGGGT 2700

GGCACGCCGT ACCCAGAACT GCCGATGAAC GAACAGTTCT ACAACGCCAT CAAGCGGGGC 2760

TACCGTATGG CCCAGCCTGC ACATGCCTCT GATGAGATCT ATGAGATCAT GCAGAAGTGC 2820

TGGGAAGAGA AGTTTGAGAT CCGGCCCCCT TTCTCCCAGC TGGTGCTGCT TCTCGAGAGA 2880

CTGCTGGGCG AGGGTTACAA AAAGAAGTAC CAGCAAGTGG ATGAGGAGTT TCTTAGGAGC 2940

GACCACCCAG CTATCCTCAG GTCTCAGGCT CGCTTGCCTG GGTTCCATGG CCTTCGGTCC 3000

CCCCTGGACA CCAGCTCTGT CCTCTACACG GCTGTGCAGC CCAACGAGAG TGACAACGAC 3060

TACATCATCC CCCTGCCAGA CACCGAGGTT GCTGATGAGG GTCCCCTGGA GGGCTCCCCC 3120

AGTCTTGCCA GCTCCACCCT GAATGAAGTC AACACATCTT CTACCATCTC CTGCGACAGC 3180

CCCCTGGAGC CCCAAGAAGA AGCAGAGGCT GAGCCACAGC TGGAGTCCTG CGTGGAGTCT 3240

GAGCCCAAAG TGGAACAGCT GCTGGATTCT GGCTGCTTCG GGATGCAGGC TGAAGTGGAG 3300

GACAGCTTCC TGTAG 3315

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         l+lG++lGsGafG+vveata+Gls+s+a++kvavkmlkstarssek+almselki+shlG

Q: 600   LVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLG  659

         78**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeeldska  120

         +h+n+vnllGactkgGpiy+iteyc+yGdl++yl+r++++fl+++++k++++++el+s+a

Q: 660   PHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNA  719

         ************************************************************

S: 121   lladkslrsksslssesseeyvdlkkd................vsdvssskadklasekk  164

         l+ +  l s++sl+ es++ y+d++kd                ++d++ss++++++++++

Q: 720   LPIGLRLPSHVSLTGESDGGYMDMSKDesvdyvpmldmkgdvkYADIESSNYMAPYDNYV  779

         ************************************************************

S: 165   ksalerevkaaleeedsevleledllsfsyqvakGmeflaskncvhrdlaarnvllteGk  224

          sa er+++a+l++e s vl+++dl+ fsyqva+Gmeflaskncvhrdlaarnvl++eGk

Q: 780   PSAPERTYRATLINE-SPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGK  838

         **************9.9*******************************************

S: 225   vvkicdfGlardimkdsnyvvkGnarlpvkwmapesifdslytvksdvwsyGillweifs  284

         +vkicdfGlardim+dsny++kG+++lp+kwmapesif+slyt+ sdvws+Gillweif+

Q: 839   LVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFT  898

         ************************************************************

S: 285   lGstpypgllvdskfyklikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlvell  344

         lG+tpyp+l+++++fy++ik+Gyrmaqpa+a++eiyeimqkcwe+++e rp+f+qlv ll

Q: 899   LGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLL  958

         ********************************************************9986

Domain Sequence
(FASTA)

LVLGRTLGSG AFGQVVEATA HGLSHSQATM KVAVKMLKST ARSSEKQALM SELKIMSHLG 60

PHLNVVNLLG ACTKGGPIYI ITEYCRYGDL VDYLHRNKHT FLQHHSDKRR PPSAELYSNA 120

LPIGLRLPSH VSLTGESDGG YMDMSKDESV DYVPMLDMKG DVKYADIESS NYMAPYDNYV 180

PSAPERTYRA TLINESPVLS YTDLVGFSYQ VANGMEFLAS KNCVHRDLAA RNVLICEGKL 240

VKICDFGLAR DIMRDSNYIS KGSTFLPLKW MAPESIFNSL YTTLSDVWSF GILLWEIFTL 300

GGTPYPELPM NEQFYNAIKR GYRMAQPAHA SDEIYEIMQK CWEEKFEIRP PFSQLVLLL 359

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>