EPS-OCP-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-OCP-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	211.4	1.5E-62	649	894	246

Status

Unreviewed

Ensembl Protein

ENSOPRP00000007833

Gene Name

PHLPP1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000008548	ENSOPRP00000007833	ENSOPRT00000008559

Organism

Ochotona princeps

Protein Length

917

Protein Sequence
(FASTA)

KPHSTSSSER IQLSGMYNVR KGKMQLPVNR WTRRQVILCG TCLIVSSVKD SLTGKMHVLP 60

LIGGKVEEVK KHQHCLAFSS SGPQSQTYYI CFDTFTEYLR WLRQVSKVAS QRISSVDLSC 120

CSLEHLPANL FYSQDLTHLN LKQNFLRQNP GLPSTRGLSE LQRFTKLKSL NLSNNHLGDF 180

PLAVCNIPTL AELNVSCNAL RAVPAAVGAM HNLQTFLLDG NFLQSLPAEL ENMHQLSYLG 240

LSFNEFIDIP EVLEKLAAVD KLCMSGNCLE TLRLQALRRM PHIKHVDLRL NIIQKIIADG 300

VDFLQHITQL DLRDNKLHEL DAMIFNNIEV LHCERNQLAT LNICGYFLKA LYASSNELVQ 360

LDVYPVPNYL SYMDVSRNHL ENVPEWVCES RKLEVLDIGH NHICELPARL FCNSSLRKLL 420

AGHNQLARLP ERLERTSVEV LDVQHNQLLE LPPNLLMKAD SLRFLNASAN KLESLPPATL 480

CEETNSILQE LYLTNNNLTD KCVPLLTGHP HLKILHMAYN RLQSFPASKM AKLEELEEID 540

ISGNKLKAIP TTILNCRRMH TVIAHSNCIE VFPEVMQLPE VKCVDLSCNE LNEVTLPENL 600

PPKLQELDLT GNPRLVLDHK TLELLNNIRC FKIDQPSAGD ASGAPAVWSH GYTEASGVKN 660

KLCVAALSVN NFCDNREALY GVFDGDRNVE VPYLLQCTMS DILAEELQKT KNEEEYMVNT 720

FIVMQRKLGT AGQKLGGSAV LCHIKHDPVD PGGSFTLTSA NVGKCQTVLC RNGKPLPLSA 780

SYVMSCEEEL KRIKQHKAIV TEDGKVNGVT ESTRILGYTF LHPSVVPRPH VQSVLLTPQD 840

EFFILGSKGL WDSLSIQEAV EAVRNVPDAL AAAKKLCHVA QSYGCHDSIS AVVVQLSGAE 900

DSFCCCELDA SGSVRPP 917

Nucleotide Sequence
(FASTA)

AAGCCTCACA GTACCAGTAG CTCTGAACGG ATTCAACTCT CAGGAATGTA TAATGTCCGG 60

AAAGGCAAAA TGCAGCTTCC GGTGAACCGG TGGACAAGAC GCCAAGTCAT CCTGTGTGGG 120

ACCTGCTTGA TAGTGTCGTC TGTGAAAGAC AGCCTAACCG GAAAGATGCA TGTTCTTCCA 180

CTTATAGGTG GAAAAGTTGA AGAAGTGAAA AAGCACCAGC ACTGTTTAGC ATTTAGCTCC 240

TCTGGACCCC AAAGCCAGAC TTACTACATC TGCTTTGATA CTTTCACAGA GTACTTACGG 300

TGGCTGCGGC AAGTCTCCAA GGTTGCATCC CAGCGCATTA GCTCTGTGGA CCTCTCGTGC 360

TGTAGCTTAG AACACCTGCC TGCCAACCTC TTCTACAGCC AGGACCTCAC TCATCTCAAT 420

TTAAAACAAA ACTTCCTAAG GCAAAACCCA GGTCTTCCAT CTACCAGGGG GCTCAGCGAA 480

CTACAAAGGT TCACCAAGTT GAAGAGTCTT AACCTTTCCA ATAATCATTT AGGAGACTTC 540

CCATTAGCAG TCTGCAATAT TCCAACCTTG GCAGAGCTGA ATGTGTCCTG CAATGCCCTG 600

CGAGCAGTCC CAGCAGCCGT CGGAGCTATG CACAACTTGC AGACATTTTT GTTGGATGGA 660

AACTTTCTCC AGTCCCTTCC TGCTGAATTG GAAAACATGC ACCAGCTTAG TTATCTTGGT 720

CTCTCCTTCA ATGAGTTTAT TGACATTCCA GAGGTATTGG AGAAGCTGGC TGCTGTGGAT 780

AAACTGTGTA TGTCTGGAAA CTGTCTGGAG ACCCTGAGGC TACAGGCTTT AAGAAGAATG 840

CCTCACATTA AGCATGTGGA TCTCAGATTG AACATAATTC AGAAGATAAT AGCAGATGGA 900

GTGGACTTTC TACAGCATAT TACTCAGCTT GACCTCCGAG ACAATAAGCT GCATGAGCTA 960

GATGCCATGA TTTTCAACAA CATTGAAGTT TTGCACTGTG AAAGGAATCA GTTGGCGACA 1020

TTAAACATTT GTGGCTATTT CCTGAAAGCA CTGTATGCCT CTTCTAATGA ACTCGTGCAG 1080

CTTGATGTTT ACCCAGTTCC AAATTATCTC TCCTACATGG ATGTTTCAAG GAACCACTTA 1140

GAAAATGTGC CTGAGTGGGT ATGTGAAAGC CGAAAGCTGG AAGTTTTGGA TATTGGCCAT 1200

AATCACATTT GTGAGCTTCC TGCCCGTTTA TTTTGTAACA GCAGTCTCCG GAAACTACTG 1260

GCAGGACACA ACCAATTGGC AAGGCTGCCT GAAAGACTTG AGAGAACCTC AGTGGAGGTC 1320

TTGGATGTGC AGCATAACCA GCTCCTGGAG TTGCCGCCGA ACCTTCTCAT GAAGGCCGAC 1380

AGCCTGAGAT TCCTGAATGC ATCTGCCAAC AAACTGGAAA GCCTTCCTCC AGCTACACTT 1440

TGTGAAGAGA CAAACAGTAT CTTGCAAGAG TTGTACTTGA CAAATAACAA CCTCACAGAC 1500

AAATGTGTGC CCTTGTTAAC AGGGCACCCC CATCTGAAGA TCCTTCACAT GGCCTATAAT 1560

AGACTCCAGA GTTTTCCAGC AAGTAAAATG GCAAAACTGG AGGAACTTGA AGAAATTGAT 1620

ATCAGTGGGA ATAAATTGAA AGCAATTCCA ACAACTATCC TGAATTGCCG GCGCATGCAC 1680

ACTGTGATTG CTCACTCCAA TTGCATCGAA GTCTTCCCTG AAGTCATGCA GCTTCCAGAA 1740

GTCAAGTGCG TGGACCTGAG CTGTAATGAG CTAAATGAAG TGACTTTACC AGAAAACCTG 1800

CCTCCCAAGC TGCAAGAACT GGACCTGACC GGAAACCCGC GCCTTGTCCT GGACCACAAG 1860

ACCCTGGAGC TGCTGAATAA CATCCGCTGT TTCAAGATTG ACCAGCCTTC GGCAGGAGAT 1920

GCATCTGGAG CCCCAGCCGT GTGGAGTCAT GGCTACACTG AGGCATCAGG GGTGAAAAAC 1980

AAGTTGTGTG TGGCAGCTCT GTCCGTGAAT AACTTCTGCG ACAACCGGGA GGCCCTGTAT 2040

GGTGTGTTTG ATGGAGACCG GAATGTGGAG GTGCCCTACC TTCTCCAGTG TACCATGAGT 2100

GACATTTTGG CTGAAGAGCT GCAGAAAACA AAAAATGAAG AAGAATACAT GGTCAATACA 2160

TTCATTGTTA TGCAGAGGAA ACTTGGAACT GCTGGGCAGA AGCTTGGAGG GTCTGCTGTC 2220

CTCTGCCACA TCAAACATGA CCCTGTGGAC CCAGGAGGCT CCTTCACCTT GACCTCTGCC 2280

AATGTGGGCA AGTGCCAAAC TGTGCTCTGT CGCAACGGGA AGCCGCTGCC ACTGTCTGCG 2340

TCGTATGTCA TGAGCTGTGA AGAAGAGCTG AAGAGGATTA AACAGCACAA GGCCATTGTC 2400

ACTGAGGACG GCAAGGTGAA CGGTGTGACT GAGTCCACAC GCATCCTGGG CTACACCTTC 2460

CTCCACCCCA GCGTGGTGCC CCGGCCCCAT GTGCAGTCCG TGCTCCTGAC GCCCCAGGAC 2520

GAGTTCTTCA TCCTGGGCAG CAAGGGCTTG TGGGACAGCC TGTCCATCCA GGAGGCCGTG 2580

GAAGCCGTGC GCAATGTGCC TGATGCCCTG GCTGCTGCCA AGAAACTGTG CCACGTGGCC 2640

CAGAGCTACG GCTGCCACGA CAGCATCAGT GCGGTGGTAG TGCAGCTCAG CGGCGCTGAG 2700

GACAGCTTCT GCTGCTGCGA GCTCGATGCC AGTGGGAGCG TGCGGCCACC C 2751

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 649   SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  703

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 704   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpvdpgg  753

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls  + +s+e+El+Ri+++++ v+++   +v+Gv++

Q: 754   sfTLTSANVGKCQTVLCRNGKPLPLSASYVMSCEEELKRIKQHKAIVTEDG--KVNGVTE  811

         *99**********************************************99..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s+ lt++def+iL+s+Glwd +s +eav++vr+v +

Q: 812   STRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIQEAVEAVRNVPD---  868

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL+++a+++g++d++sa+vv

Q: 869   -ALAAAKKLCHVAQSYGCHDSISAVVV  894

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP VDPGGSFTLT SANVGKCQTV 120

LCRNGKPLPL SASYVMSCEE ELKRIKQHKA IVTEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVLLTP QDEFFILGSK GLWDSLSIQE AVEAVRNVPD ALAAAKKLCH VAQSYGCHDS 240

ISAVVV 246

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>