EKS-OCP-00140

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00140

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	566.9	1.1E-170	139	493	355

Status

Unreviewed

Ensembl Protein

ENSOPRP00000009917

Gene Name

PINK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000010836	ENSOPRP00000009917	ENSOPRT00000010854

Organism

Ochotona princeps

Protein Length

563

Protein Sequence
(FASTA)

MVRQALRGLQ LRALLLRFAT KPGPAYSGRP GPVPWGRLRP GRAAPGLQPR RVGWRLPDRY 60

RFFRQVAGLA LQQFMMRAGG AGPGGRAVFL AFLGLLIEEQ AESRRAHACE IQAIFTQKSK 120

LGADPLDGRR WQGFRLEEYL IGQSIGKGCS AAVYEATVAA LHVNLEVAEG TRLPGRGTDL 180

TKAGTTKVPG PGAPHFPLAI KMMWNISAGS SSEAIFRTMS QELVPASRVA LAGEYGAVVH 240

RKTKGSPKQL APHPNIIRVF RAFTSSVPLL PGALVDYPDM LPPRLHPQGL GHGRTLFLVM 300

KNYPCTLRQY LRETPSPRLA MLMTLQLLEG VAHLVQQGIA HRDLKSDNVL VELDADGCPW 360

LVITDFGCCL ADERVGLRLP FPSWYVDRGG NGCLMAPEVS TAHPGPRTVI DYSKADAWAV 420

GAIAYEIFGL ANPFYGQGRA RLESRSYLET QLPALPRSVP PDARQLLRSL LQREPYKRPS 480

ARVAANVLHL SLWGEHLLAL KNLELDKMVG WLLQQSAVAL LTNRLAERSC VETKMKMLFL 540

ANLECDALCQ AALLLRAWRA APG 563

Nucleotide Sequence
(FASTA)

ATGGTGCGAC AGGCGCTGCG GGGCCTGCAG CTGCGCGCGC TGCTCCTACG CTTCGCGACC 60

AAGCCTGGCC CGGCCTATAG CGGGCGGCCC GGCCCGGTGC CGTGGGGCCG CCTGCGCCCG 120

GGCCGGGCCG CACCCGGCCT GCAGCCGCGC AGGGTCGGGT GGAGGCTTCC CGACCGCTAC 180

CGCTTCTTCC GCCAGGTAGC AGGACTGGCG CTGCAGCAGT TCATGATGCG AGCCGGCGGC 240

GCGGGTCCTG GCGGCCGGGC CGTCTTTCTG GCCTTCCTGG GCCTGCTCAT TGAGGAGCAG 300

GCGGAGAGCC GCCGAGCGCA CGCCTGTGAG ATCCAGGCCA TTTTCACCCA GAAAAGCAAG 360

CTGGGAGCTG ACCCCCTGGA TGGCAGGCGC TGGCAGGGCT TCCGGCTGGA GGAGTACCTG 420

ATCGGGCAGT CCATTGGCAA GGGCTGCAGC GCTGCTGTGT ACGAAGCCAC CGTGGCTGCG 480

TTGCATGTGA ACCTGGAGGT GGCAGAAGGC ACCAGGCTTC CCGGGAGAGG CACGGACCTC 540

ACTAAAGCAG GAACGACCAA GGTGCCCGGC CCTGGGGCCC CCCACTTTCC CTTGGCCATC 600

AAGATGATGT GGAACATCTC GGCGGGCTCT TCCAGCGAGG CCATCTTCAG GACTATGAGC 660

CAGGAGCTCG TTCCAGCCAG CCGTGTGGCC CTGGCCGGGG AGTACGGAGC CGTTGTTCAT 720

AGAAAGACCA AGGGGAGCCC CAAGCAGCTG GCCCCTCACC CCAACATCAT CCGCGTTTTC 780

CGCGCCTTCA CCTCGTCTGT GCCGCTGCTG CCAGGGGCCC TGGTGGACTA CCCTGATATG 840

CTGCCCCCTC GCCTCCACCC TCAGGGCCTG GGCCATGGCC GCACGCTGTT CCTCGTGATG 900

AAAAACTACC CCTGCACCCT GCGTCAGTAC CTGCGCGAGA CCCCCAGCCC CCGCCTGGCC 960

ATGCTGATGA CCCTGCAGTT GCTGGAGGGC GTGGCTCACC TGGTGCAGCA GGGCATCGCG 1020

CACAGAGACC TGAAGTCGGA CAACGTTCTC GTGGAGCTGG ACGCAGATGG CTGTCCCTGG 1080

CTGGTGATCA CCGATTTTGG CTGCTGCCTG GCTGATGAAC GCGTTGGCCT GCGACTGCCT 1140

TTCCCCAGCT GGTACGTGGA TCGGGGCGGC AACGGCTGTC TGATGGCCCC GGAGGTGTCC 1200

ACGGCCCATC CGGGCCCCAG GACAGTGATT GACTACAGCA AGGCCGACGC CTGGGCCGTG 1260

GGAGCCATTG CCTATGAGAT CTTCGGGCTT GCCAATCCCT TTTACGGCCA GGGCAGGGCC 1320

CGCCTTGAGA GCCGCAGTTA CCTGGAGACC CAGCTGCCTG CCCTCCCTCG GTCGGTGCCT 1380

CCGGATGCCA GACAGCTCTT GAGGTCCCTG CTCCAGCGAG AGCCCTACAA GAGGCCATCT 1440

GCCCGAGTCG CTGCAAACGT GCTGCATTTA AGCCTCTGGG GGGAGCATCT TCTAGCCCTG 1500

AAGAACCTGG AGCTGGACAA GATGGTGGGC TGGCTTCTTC AGCAGTCAGC TGTCGCCCTG 1560

CTGACCAACA GGCTTGCAGA GAGGAGCTGC GTGGAGACAA AGATGAAGAT GCTGTTTCTG 1620

GCCAACCTGG AGTGTGACGC ACTGTGCCAG GCAGCCCTGC TACTGCGTGC ATGGCGGGCG 1680

GCCCCGGGG 1689

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgllgkevtvvlaeidqesavaakkfpl  60

         ylig+++gkgc+aavyeat+a+l+ +le+a+ + l g++++ + a++ ++  ++a++fpl

Q: 139   YLIGQSIGKGCSAAVYEATVAALHVNLEVAEGTRLPGRGTDLTKAGTTKVPGPGAPHFPL  198

         99**********************************************************

S: 61    aiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPnivr  112

         aik+m+ni+a+sssea++++msqelvpasrval+geygav        pk+la+hPni+r

Q: 199   AIKMMWNISAGSSSEAIFRTMSQELVPASRVALAGEYGAVvhrktkgsPKQLAPHPNIIR  258

         ************************************************************

S: 113   vlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrst  172

         v+raf++sv+llP+al+dyPd+lp+rl+p+glg+g+tl+lvmk+y++tlr+yl  +++s+

Q: 259   VFRAFTSSVPLLPGALVDYPDMLPPRLHPQGLGHGRTLFLVMKNYPCTLRQYLR-ETPSP  317

         *****************************************************7.589**

S: 173   rlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdgl  232

         rla+l+++qlle+v hlv++g+ahrdlksdn+lveld d++P+lvi+dfGCclad+ +gl

Q: 318   RLAMLMTLQLLEGVAHLVQQGIAHRDLKSDNVLVELDADGCPWLVITDFGCCLADERVGL  377

         ************************************************************

S: 233   rlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyge  292

         rlp+ s++vd+GGn++lmaPe+sta+pGp++vi+y+kad+WavGa+ayeifgl+nPfyg+

Q: 378   RLPFPSWYVDRGGNGCLMAPEVSTAHPGPRTVIDYSKADAWAVGAIAYEIFGLANPFYGQ  437

         ************************************************************

S: 293   gkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

         g+a les+sy e+qlPalp svpp++rql+++ll+re+ kr+sa++aanvl+lsl+

Q: 438   GRARLESRSYLETQLPALPRSVPPDARQLLRSLLQREPYKRPSARVAANVLHLSLW  493

         *******************************************************9

Domain Sequence
(FASTA)

YLIGQSIGKG CSAAVYEATV AALHVNLEVA EGTRLPGRGT DLTKAGTTKV PGPGAPHFPL 60

AIKMMWNISA GSSSEAIFRT MSQELVPASR VALAGEYGAV VHRKTKGSPK QLAPHPNIIR 120

VFRAFTSSVP LLPGALVDYP DMLPPRLHPQ GLGHGRTLFL VMKNYPCTLR QYLRETPSPR 180

LAMLMTLQLL EGVAHLVQQG IAHRDLKSDN VLVELDADGC PWLVITDFGC CLADERVGLR 240

LPFPSWYVDR GGNGCLMAPE VSTAHPGPRT VIDYSKADAW AVGAIAYEIF GLANPFYGQG 300

RARLESRSYL ETQLPALPRS VPPDARQLLR SLLQREPYKR PSARVAANVL HLSLW 355

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>