EKS-OCP-00072

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-OCP-00072

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Tec	471.0	5.8E-142	362	611	250

Status

Unreviewed

Ensembl Protein

ENSOPRP00000011696

Gene Name

ITK

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOPRG00000012795	ENSOPRP00000011696	ENSOPRT00000012806

Organism

Ochotona princeps

Protein Length

620

Protein Sequence
(FASTA)

MNNFILLEEQ IKKSQQKRRT SPSNFKVRFF VLTKSSLAYF EDRNGKKRTL KGSIELSRIK 60

CVEIVKSDIS IPCHYKYPFQ VVHDNYLLYV FAPDRESRQR WVLALKEETR NNNNLVSKYH 120

PNFWMDGRWR CCSQLEKLAV GCAQYDPTKN ASKKPLPPTP EDNRRSLREA EETLVIALYD 180

YQTNDPQELA LQRNEEYYLL DSSEIHWWRV QDRNGHEGYV PSSYLVEKSP NNLETHEWYN 240

KSISRDKAEK LLLDTGKEGA FMVRDSRTPG TYTVSVFTKA VVSENNPCIK HYHIKETNDN 300

PKRYYVAEKY VFDSIPQLIK YHQHNGGGLV TRLRHPVSSW RQKAPVTAGL RYGKWVIDPS 360

ELTFVQEIGS GQFGLVHLGY WLNKHKVAIK TIREGAMSEE DFIEEAEVMM KLSHPKLVQL 420

YGVCLEQAPI CLVFEFMEHG CLSDYLRNKR GLFAAETLLG MCLDVCEGMA YLEEECFIHR 480

DLAARNCLVG ENQVIKVSDF GMTRFVLDDQ YTSSTGTKFP VKWASPEVFS FSRYSSKSDV 540

WSFGVLMWEV FSEGKIPYEN RSNSEVVEDI STGFRLYKPR LASSNIYQIM NHCWKERPED 600

RPPFSRLRGQ LSEIAESGLQ 620

Nucleotide Sequence
(FASTA)

ATGAACAACT TCATCCTTCT GGAAGAACAG ATCAAGAAAT CCCAACAGAA GAGGAGAACT 60

TCCCCTTCAA ACTTTAAAGT CCGTTTCTTT GTCCTGACCA AAAGCAGCCT GGCATACTTT 120

GAGGATCGTA ATGGGAAAAA GCGCACGTTG AAGGGATCCA TTGAACTCTC CCGAATCAAA 180

TGTGTCGAGA TTGTGAAGAG TGACATTAGC ATCCCATGCC ATTATAAATA CCCGTTTCAG 240

GTTGTACATG ACAACTACCT CCTGTATGTG TTTGCTCCAG ACCGTGAGAG CCGACAGCGC 300

TGGGTGCTAG CCCTTAAAGA AGAAACGAGG AATAATAACA ATTTGGTGTC CAAATATCAC 360

CCTAACTTCT GGATGGACGG GAGGTGGAGA TGCTGTTCTC AGCTGGAGAA ACTTGCAGTG 420

GGCTGTGCCC AGTATGATCC AACCAAAAAC GCCTCGAAGA AGCCTCTTCC TCCTACTCCC 480

GAGGACAACA GGAGGTCACT TCGGGAAGCT GAGGAAACCC TGGTCATTGC CCTATATGAC 540

TACCAAACAA ATGACCCTCA GGAGCTTGCA TTGCAGCGGA ACGAGGAGTA TTACCTGCTG 600

GACAGTTCCG AGATTCACTG GTGGAGAGTT CAGGACAGGA ATGGGCATGA AGGATATGTA 660

CCAAGCAGTT ATCTGGTGGA AAAATCTCCA AATAACCTGG AAACTCATGA GTGGTACAAC 720

AAGAGCATCA GCCGAGACAA AGCTGAAAAG CTCCTTTTAG ACACGGGCAA AGAAGGAGCC 780

TTCATGGTCC GAGATTCCAG GACTCCAGGC ACCTACACTG TGTCTGTCTT CACTAAGGCT 840

GTTGTAAGTG AGAACAACCC CTGTATAAAG CATTATCATA TCAAAGAAAC TAACGACAAC 900

CCCAAGCGAT ACTATGTGGC TGAAAAGTAC GTGTTTGACT CCATCCCGCA GCTCATCAAG 960

TACCACCAAC ACAATGGAGG AGGTCTGGTC ACACGACTCC GCCATCCAGT TTCTTCTTGG 1020

AGACAAAAAG CCCCAGTCAC AGCAGGGCTG CGATATGGGA AATGGGTGAT TGATCCGTCA 1080

GAGCTCACTT TTGTGCAGGA GATTGGCAGT GGGCAGTTTG GGTTAGTGCA TCTTGGCTAC 1140

TGGCTCAACA AGCACAAGGT GGCCATCAAA ACCATTCGGG AGGGAGCTAT GTCGGAAGAA 1200

GACTTCATAG AGGAAGCTGA AGTCATGATG AAACTCTCCC ACCCCAAACT GGTCCAGCTC 1260

TACGGAGTGT GCCTGGAGCA AGCACCCATC TGCCTGGTGT TTGAGTTCAT GGAGCACGGC 1320

TGCCTGTCAG ATTACCTGCG CAACAAGCGG GGGCTCTTTG CTGCGGAGAC CCTGCTGGGC 1380

ATGTGCCTGG ATGTGTGTGA GGGCATGGCC TACCTGGAAG AGGAATGTTT CATCCACAGG 1440

GACCTGGCTG CCCGAAACTG TTTGGTGGGA GAAAACCAAG TCATCAAGGT GTCGGACTTC 1500

GGGATGACAA GGTTTGTCCT CGATGATCAA TACACGAGTT CCACAGGCAC CAAGTTCCCA 1560

GTGAAGTGGG CCTCTCCAGA AGTCTTCTCC TTCAGTCGCT ACAGCAGCAA GTCAGATGTG 1620

TGGTCCTTTG GTGTGCTCAT GTGGGAAGTC TTCAGTGAAG GCAAAATCCC ATACGAGAAC 1680

CGGAGCAACT CGGAGGTGGT AGAGGACATC AGCACCGGAT TTCGGTTGTA CAAGCCCCGT 1740

CTGGCCTCCT CCAACATCTA CCAGATCATG AACCATTGCT GGAAAGAGAG ACCAGAAGAC 1800

CGGCCACCAT TCTCGAGGCT AAGGGGTCAG CTGTCTGAAA TCGCAGAATC AGGACTTCAG 1860

Domain Profile

S: 1     ltllkelgsgqfgvvklgkwrakidvaikaikegamseedfieeakvmmklshpklvqly  60

         lt+++e+gsgqfg+v+lg+w +k++vaik+i+egamseedfieea+vmmklshpklvqly

Q: 362   LTFVQEIGSGQFGLVHLGYWLNKHKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLY  421

         79**********************************************************

S: 61    gvclkqkpiyivteylengcllnylrekkkklekelllemckdvcegmeylerksfihrd  120

         gvcl+q+pi++v+e++e+gcl++ylr+k++ +++e+ll mc dvcegm+yle+++fihrd

Q: 422   GVCLEQAPICLVFEFMEHGCLSDYLRNKRGLFAAETLLGMCLDVCEGMAYLEEECFIHRD  481

         ************************************************************

S: 121   laarnclvdeelvvkvsdfglaryvlddqyvssvgakfpvkwsppevlsyskyssksdvw  180

         laarnclv+e++v+kvsdfg++r+vlddqy+ss+g+kfpvkw++pev+s+s+yssksdvw

Q: 482   LAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVW  541

         ************************************************************

S: 181   afgvlmwevfsegklpyekksnsevvekvsrglrlyrpklaskkvyevmkscwkekpeer  240

         +fgvlmwevfsegk+pye++snsevve++s+g+rly+p+las+++y++m++cwke+pe+r

Q: 542   SFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASSNIYQIMNHCWKERPEDR  601

         ************************************************************

S: 241   ptfkellsal  250

         p f++l  +l

Q: 602   PPFSRLRGQL  611

         ****997776

Domain Sequence
(FASTA)

LTFVQEIGSG QFGLVHLGYW LNKHKVAIKT IREGAMSEED FIEEAEVMMK LSHPKLVQLY 60

GVCLEQAPIC LVFEFMEHGC LSDYLRNKRG LFAAETLLGM CLDVCEGMAY LEEECFIHRD 120

LAARNCLVGE NQVIKVSDFG MTRFVLDDQY TSSTGTKFPV KWASPEVFSF SRYSSKSDVW 180

SFGVLMWEVF SEGKIPYENR SNSEVVEDIS TGFRLYKPRL ASSNIYQIMN HCWKERPEDR 240

PPFSRLRGQL 250

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>